AU2002257177B2 - Methods and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry - Google Patents

Methods and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry Download PDF

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Publication number
AU2002257177B2
AU2002257177B2 AU2002257177A AU2002257177A AU2002257177B2 AU 2002257177 B2 AU2002257177 B2 AU 2002257177B2 AU 2002257177 A AU2002257177 A AU 2002257177A AU 2002257177 A AU2002257177 A AU 2002257177A AU 2002257177 B2 AU2002257177 B2 AU 2002257177B2
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AU
Australia
Prior art keywords
electrodes
ions
ion
filter
flow path
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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AU2002257177A
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English (en)
Other versions
AU2002257177A1 (en
Inventor
Gary A. Eiceman
Evgeny Krylov
Raanan A. Miller
Erkinjon G. Nazarov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Charles Stark Draper Laboratory Inc
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Charles Stark Draper Laboratory Inc
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Filing date
Publication date
Priority claimed from US10/123,030 external-priority patent/US6690004B2/en
Application filed by Charles Stark Draper Laboratory Inc filed Critical Charles Stark Draper Laboratory Inc
Publication of AU2002257177A1 publication Critical patent/AU2002257177A1/en
Application granted granted Critical
Publication of AU2002257177B2 publication Critical patent/AU2002257177B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165—Electrospray ionisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Plasma & Fusion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
AU2002257177A 2001-04-17 2002-04-17 Methods and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry Ceased AU2002257177B2 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US83649501A 2001-04-17 2001-04-17
US09/836,495 2001-04-17
US4097402A 2002-01-07 2002-01-07
US10/040,974 2002-01-07
US10/123,030 2002-04-12
US10/123,030 US6690004B2 (en) 1999-07-21 2002-04-12 Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
PCT/US2002/012210 WO2002083276A1 (en) 2001-04-17 2002-04-17 Methods and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry

Publications (2)

Publication Number Publication Date
AU2002257177A1 AU2002257177A1 (en) 2003-04-17
AU2002257177B2 true AU2002257177B2 (en) 2004-11-25

Family

ID=27365820

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002257177A Ceased AU2002257177B2 (en) 2001-04-17 2002-04-17 Methods and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry

Country Status (7)

Country Link
EP (1) EP1387724A4 (ja)
JP (1) JP4063676B2 (ja)
CN (1) CN1585666A (ja)
AU (1) AU2002257177B2 (ja)
CA (1) CA2444257A1 (ja)
IL (1) IL158386A0 (ja)
WO (1) WO2002083276A1 (ja)

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US7005632B2 (en) 2002-04-12 2006-02-28 Sionex Corporation Method and apparatus for control of mobility-based ion species identification
US7098449B1 (en) 1999-07-21 2006-08-29 The Charles Stark Draper Laboratory, Inc. Spectrometer chip assembly
US7129482B2 (en) 1999-07-21 2006-10-31 Sionex Corporation Explosives detection using differential ion mobility spectrometry
US7091481B2 (en) 2001-08-08 2006-08-15 Sionex Corporation Method and apparatus for plasma generation
US6727496B2 (en) 2001-08-14 2004-04-27 Sionex Corporation Pancake spectrometer
US6787765B2 (en) * 2002-02-08 2004-09-07 Ionalytics Corporation FAIMS with non-destructive detection of selectively transmitted ions
US7122794B1 (en) 2002-02-21 2006-10-17 Sionex Corporation Systems and methods for ion mobility control
AU2003298597A1 (en) 2002-10-12 2004-05-25 Sionex Corporation NOx MONITOR USING DIFFERENTIAL MOBILITY SPECTROMETRY
WO2004114347A2 (en) * 2003-06-20 2004-12-29 Brigham Young University Single device for ion mobility and ion trap mass spectrometry
WO2005028973A2 (en) 2003-09-17 2005-03-31 Sionex Corporation Solid-state flow generator and related systems, applications, and methods
CA2547389A1 (en) 2003-11-25 2005-06-09 Sionex Corporation Mobility based apparatus and methods using dispersion characteristics, sample fragmentation, and/or pressure control to improve analysis of a sample
US7456394B2 (en) * 2004-02-02 2008-11-25 Sionex Corporation Compact sample analysis systems and related methods of using combined chromatography and mobility spectrometry techniques
US6967326B2 (en) * 2004-02-27 2005-11-22 Lucent Technologies Inc. Mass spectrometers on wafer-substrates
GB0503010D0 (en) * 2005-02-14 2005-03-16 Micromass Ltd Mass spectrometer
US8440968B2 (en) 2005-02-14 2013-05-14 Micromass Uk Limited Ion-mobility analyser
WO2006103465A2 (en) * 2005-04-01 2006-10-05 Micromass Uk Limited Mass spectrometer
US8581178B2 (en) 2005-05-24 2013-11-12 Dh Technologies Development Pte. Ltd. Combined mass and differential mobility spectrometry and associated methods, systems, and devices
US7977627B2 (en) * 2006-01-10 2011-07-12 Smith Detection-Watford Limited Ion selection apparatus and method
EP2126960B1 (en) * 2007-02-01 2019-03-13 DH Technologies Development Pte. Ltd. Differential mobility spectrometer pre-filter assembly for a mass spectrometer
WO2008097962A2 (en) * 2007-02-05 2008-08-14 Excellims Corporation Methods and apparatus of ion mobility spectrometer
GB0708391D0 (en) * 2007-05-01 2007-06-06 Smiths Detection Watford Ltd Detection and spectrometers
US7863562B2 (en) * 2007-06-22 2011-01-04 Shimadzu Corporation Method and apparatus for digital differential ion mobility separation
CN101082594B (zh) * 2007-07-06 2010-12-15 清华大学 物质成分测定装置
CN101738417B (zh) * 2009-12-08 2012-09-05 清华大学 基于冷场电子检测生化物质的芯片及检测方法
US8389930B2 (en) * 2010-04-30 2013-03-05 Agilent Technologies, Inc. Input port for mass spectrometers that is adapted for use with ion sources that operate at atmospheric pressure
CN102479664A (zh) * 2010-11-30 2012-05-30 中国科学院大连化学物理研究所 一种平板式离子迁移谱
CN102478545A (zh) * 2010-11-30 2012-05-30 中国科学院大连化学物理研究所 一种平板式差分式离子迁移谱
EP2786400B1 (en) 2011-11-29 2017-01-18 Dh Technologies Development Pte. Ltd. METHODS of MASS ANALYSIS USING DIFFERENTIAL MOBILITY SPECTROMETERS
CN103163206A (zh) * 2011-12-19 2013-06-19 中国科学院大连化学物理研究所 一种复合电离源差分式离子迁移谱
JP6346567B2 (ja) * 2011-12-28 2018-06-20 マイクロマス・ユーケー・リミテッド 液相試料の急速蒸発イオン化を行うためのシステムおよび方法
CN102636553B (zh) * 2012-03-23 2014-05-28 哈尔滨工业大学（威海） 纸基电喷雾离子迁移谱分析方法
CN102683151B (zh) * 2012-05-15 2015-01-28 中国科学院合肥物质科学研究院 一种选择控制反应离子的化学电离质谱仪
CN102723254B (zh) * 2012-06-20 2015-07-22 清华大学 平板型高场非对称波形离子迁移谱仪的聚焦装置及方法
JP5997650B2 (ja) * 2013-04-15 2016-09-28 株式会社日立ハイテクノロジーズ 分析システム
FI124792B (fi) 2013-06-20 2015-01-30 Helsingin Yliopisto Menetelmä ja laite näytekaasuvirtauksen partikkelien ionisoimiseksi
JP6492090B2 (ja) * 2013-12-31 2019-03-27 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 高効率イオンガイドを用いる真空ｄｍｓ
EP3167270B1 (en) 2014-07-07 2024-03-13 Nanotech Analysis S.R.L. Portable electronic system for the analysis of time-variable gaseous flows
JP6350391B2 (ja) * 2015-05-22 2018-07-04 株式会社島津製作所 放電イオン化検出器
JP6456863B2 (ja) * 2016-03-04 2019-01-23 株式会社日立ハイテクノロジーズ イオン移動度分離部を備える分析装置
JP6926544B2 (ja) * 2016-08-05 2021-08-25 株式会社リコー 洗浄用空気作成装置及び計測システム
CN107357835B (zh) * 2017-06-22 2020-11-03 电子科技大学 一种基于主题模型和遗忘规律的兴趣预测挖掘方法及系统
GB2566326A (en) * 2017-09-11 2019-03-13 Owlstone Inc Ion mobility filter
CN109884157B (zh) * 2017-12-06 2021-06-15 中国科学院大连化学物理研究所 一种新型正负离子快速切换的离子探测器
JP7102733B2 (ja) 2018-01-04 2022-07-20 株式会社リコー イオン検出装置及び電界非対称波形イオン移動度分光分析システム
CN108760637B (zh) * 2018-07-13 2023-11-21 金华职业技术学院 一种研究分子光异构化的装置
CN110596401B (zh) * 2019-09-11 2024-05-14 宁波盘福生物科技有限公司 用于蛋白质检测的高场不对称波形离子淌度装置及方法

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US6066848A (en) * 1998-06-09 2000-05-23 Combichem, Inc. Parallel fluid electrospray mass spectrometer
WO2001008455A1 (en) * 1999-07-21 2001-02-01 Exatec, Llc. Method of promoting uniform process conditions in pecvd reactor for batch production of glazing panels

Also Published As

Publication number Publication date
JP2004529467A (ja) 2004-09-24
IL158386A0 (en) 2004-05-12
CN1585666A (zh) 2005-02-23
WO2002083276A1 (en) 2002-10-24
JP4063676B2 (ja) 2008-03-19
EP1387724A4 (en) 2006-03-15
EP1387724A1 (en) 2004-02-11
CA2444257A1 (en) 2002-10-24

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MK14 Patent ceased section 143(a) (annual fees not paid) or expired