CN1585666A - 用于电喷雾增强的高电场非对称离子淌度光谱测定仪的方法和装置 - Google Patents

用于电喷雾增强的高电场非对称离子淌度光谱测定仪的方法和装置 Download PDF

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Publication number
CN1585666A
CN1585666A CN02812130.9A CN02812130A CN1585666A CN 1585666 A CN1585666 A CN 1585666A CN 02812130 A CN02812130 A CN 02812130A CN 1585666 A CN1585666 A CN 1585666A
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China
Prior art keywords
ion
electrode
filter
flow path
electric field
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CN02812130.9A
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English (en)
Chinese (zh)
Inventor
拉安安·A·米勒
欧金琼·G·纳泽罗
加里·A·埃斯曼
埃吉尼·克里洛维
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Charles Stark Draper Laboratory Inc
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Charles Stark Draper Laboratory Inc
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Priority claimed from US10/123,030 external-priority patent/US6690004B2/en
Application filed by Charles Stark Draper Laboratory Inc filed Critical Charles Stark Draper Laboratory Inc
Publication of CN1585666A publication Critical patent/CN1585666A/zh
Pending legal-status Critical Current

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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165—Electrospray ionisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Plasma & Fusion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
CN02812130.9A 2001-04-17 2002-04-17 用于电喷雾增强的高电场非对称离子淌度光谱测定仪的方法和装置 Pending CN1585666A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US83649501A 2001-04-17 2001-04-17
US09/836,495 2001-04-17
US4097402A 2002-01-07 2002-01-07
US10/040,974 2002-01-07
US10/123,030 US6690004B2 (en) 1999-07-21 2002-04-12 Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
US10/123,030 2002-04-12

Publications (1)

Publication Number Publication Date
CN1585666A true CN1585666A (zh) 2005-02-23

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ID=27365820

Family Applications (1)

Application Number Title Priority Date Filing Date
CN02812130.9A Pending CN1585666A (zh) 2001-04-17 2002-04-17 用于电喷雾增强的高电场非对称离子淌度光谱测定仪的方法和装置

Country Status (7)

Country Link
EP (1) EP1387724A4 (ja)
JP (1) JP4063676B2 (ja)
CN (1) CN1585666A (ja)
AU (1) AU2002257177B2 (ja)
CA (1) CA2444257A1 (ja)
IL (1) IL158386A0 (ja)
WO (1) WO2002083276A1 (ja)

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CN101082594B (zh) * 2007-07-06 2010-12-15 清华大学 物质成分测定装置
CN102237249A (zh) * 2010-04-30 2011-11-09 安捷伦科技有限公司 适于在大气压下操作的离子源的质谱仪用输入端口
CN102478545A (zh) * 2010-11-30 2012-05-30 中国科学院大连化学物理研究所 一种平板式差分式离子迁移谱
CN102479664A (zh) * 2010-11-30 2012-05-30 中国科学院大连化学物理研究所 一种平板式离子迁移谱
CN102636553A (zh) * 2012-03-23 2012-08-15 哈尔滨工业大学（威海） 纸基电喷雾离子迁移谱分析方法
CN101738417B (zh) * 2009-12-08 2012-09-05 清华大学 基于冷场电子检测生化物质的芯片及检测方法
CN102683151A (zh) * 2012-05-15 2012-09-19 中国科学院合肥物质科学研究院 一种选择控制反应离子的化学电离质谱仪
CN102723254A (zh) * 2012-06-20 2012-10-10 清华大学 平板型高场非对称波形离子迁移谱仪的聚焦装置及方法
CN103163206A (zh) * 2011-12-19 2013-06-19 中国科学院大连化学物理研究所 一种复合电离源差分式离子迁移谱
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CN105122051A (zh) * 2013-04-15 2015-12-02 株式会社日立高新技术 分析系统
CN105308715A (zh) * 2013-06-20 2016-02-03 赫尔辛基大学 用于对样品气体流的粒子离子化的方法和装置
CN105874331A (zh) * 2013-12-31 2016-08-17 Dh科技发展私人贸易有限公司 使用高效离子导向器的真空dms
CN106168614A (zh) * 2015-05-22 2016-11-30 株式会社岛津制作所 放电离子化检测器
CN106885838A (zh) * 2007-02-05 2017-06-23 卓漂仪谱公司 离子迁移谱仪与方法
CN107357835A (zh) * 2017-06-22 2017-11-17 电子科技大学 一种基于主题模型和遗忘规律的兴趣预测挖掘方法及系统
CN108603860A (zh) * 2016-03-04 2018-09-28 株式会社日立高新技术 具备离子迁移率分离部的分析装置
CN108760637A (zh) * 2018-07-13 2018-11-06 金华职业技术学院 一种研究分子光异构化的装置
CN109270155A (zh) * 2011-12-28 2019-01-25 英国质谱有限公司 用于液相样品的快速蒸发电离的系统和方法
CN110006985A (zh) * 2018-01-04 2019-07-12 株式会社理光 离子检测装置及其制造方法、faims系统
CN106687808B (zh) * 2014-07-07 2019-08-20 纳米技术分析责任有限公司 用于分析时变气流的便携式电子系统
CN110596401A (zh) * 2019-09-11 2019-12-20 宁波盘福生物科技有限公司 用于蛋白质检测的高场不对称波形离子淌度装置及方法

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US6690004B2 (en) 1999-07-21 2004-02-10 The Charles Stark Draper Laboratory, Inc. Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
US7098449B1 (en) 1999-07-21 2006-08-29 The Charles Stark Draper Laboratory, Inc. Spectrometer chip assembly
US7129482B2 (en) 1999-07-21 2006-10-31 Sionex Corporation Explosives detection using differential ion mobility spectrometry
US7057168B2 (en) 1999-07-21 2006-06-06 Sionex Corporation Systems for differential ion mobility analysis
US6806463B2 (en) 1999-07-21 2004-10-19 The Charles Stark Draper Laboratory, Inc. Micromachined field asymmetric ion mobility filter and detection system
US7148477B2 (en) 1999-07-21 2006-12-12 Sionex Corporation System for trajectory-based ion species identification
US7091481B2 (en) 2001-08-08 2006-08-15 Sionex Corporation Method and apparatus for plasma generation
US6727496B2 (en) 2001-08-14 2004-04-27 Sionex Corporation Pancake spectrometer
US6998608B2 (en) * 2002-02-08 2006-02-14 Ionalytics Corporation FAIMS with non-destructive detection of selectively transmitted ions
US7122794B1 (en) 2002-02-21 2006-10-17 Sionex Corporation Systems and methods for ion mobility control
AU2003298597A1 (en) 2002-10-12 2004-05-25 Sionex Corporation NOx MONITOR USING DIFFERENTIAL MOBILITY SPECTROMETRY
WO2004114347A2 (en) * 2003-06-20 2004-12-29 Brigham Young University Single device for ion mobility and ion trap mass spectrometry
US7223970B2 (en) 2003-09-17 2007-05-29 Sionex Corporation Solid-state gas flow generator and related systems, applications, and methods
US7227134B2 (en) 2003-11-25 2007-06-05 Sionex Corporation Mobility based apparatus and methods using dispersion characteristics, sample fragmentation, and/or pressure control to improve analysis of a sample
WO2005074584A2 (en) * 2004-02-02 2005-08-18 Sionex Corporation Compact sample analysis systems and related methods using combined chromatography and mobility spectrometry techniques
US6967326B2 (en) * 2004-02-27 2005-11-22 Lucent Technologies Inc. Mass spectrometers on wafer-substrates
US8440968B2 (en) 2005-02-14 2013-05-14 Micromass Uk Limited Ion-mobility analyser
GB0503010D0 (en) * 2005-02-14 2005-03-16 Micromass Ltd Mass spectrometer
JP5219274B2 (ja) * 2005-04-01 2013-06-26 マイクロマス ユーケー リミテッド 質量分析計
WO2006127974A1 (en) * 2005-05-24 2006-11-30 Sionex Corporation Combined mass and differential mobility spectrometry
PL1971855T3 (pl) * 2006-01-10 2018-10-31 Smiths Detection-Watford Limited Urządzenie i sposób selekcji jonów
US8217344B2 (en) * 2007-02-01 2012-07-10 Dh Technologies Development Pte. Ltd. Differential mobility spectrometer pre-filter assembly for a mass spectrometer
US7863562B2 (en) * 2007-06-22 2011-01-04 Shimadzu Corporation Method and apparatus for digital differential ion mobility separation
WO2013080004A1 (en) * 2011-11-29 2013-06-06 Dh Technologies Development Pte. Ltd. Differential mobility spectrometer and methods thereof
JP6926544B2 (ja) * 2016-08-05 2021-08-25 株式会社リコー 洗浄用空気作成装置及び計測システム
GB2566326A (en) * 2017-09-11 2019-03-13 Owlstone Inc Ion mobility filter
CN109884157B (zh) * 2017-12-06 2021-06-15 中国科学院大连化学物理研究所 一种新型正负离子快速切换的离子探测器
GB202304891D0 (en) * 2023-03-31 2023-05-17 Univ Liverpool Apparatus and method

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CN106885838A (zh) * 2007-02-05 2017-06-23 卓漂仪谱公司 离子迁移谱仪与方法
CN101680857B (zh) * 2007-05-01 2015-06-10 史密斯探测-沃特福特有限公司 包括用于滤波的间隔电极的离子迁移率光谱仪
CN101082594B (zh) * 2007-07-06 2010-12-15 清华大学 物质成分测定装置
CN101738417B (zh) * 2009-12-08 2012-09-05 清华大学 基于冷场电子检测生化物质的芯片及检测方法
CN102237249A (zh) * 2010-04-30 2011-11-09 安捷伦科技有限公司 适于在大气压下操作的离子源的质谱仪用输入端口
CN102237249B (zh) * 2010-04-30 2016-08-17 安捷伦科技有限公司 适于在大气压下操作的离子源的质谱仪用输入端口
CN102478545A (zh) * 2010-11-30 2012-05-30 中国科学院大连化学物理研究所 一种平板式差分式离子迁移谱
CN102479664A (zh) * 2010-11-30 2012-05-30 中国科学院大连化学物理研究所 一种平板式离子迁移谱
CN103163206A (zh) * 2011-12-19 2013-06-19 中国科学院大连化学物理研究所 一种复合电离源差分式离子迁移谱
CN109270155A (zh) * 2011-12-28 2019-01-25 英国质谱有限公司 用于液相样品的快速蒸发电离的系统和方法
CN109270155B (zh) * 2011-12-28 2021-09-10 英国质谱有限公司 用于液相样品的快速蒸发电离的系统和方法
CN102636553B (zh) * 2012-03-23 2014-05-28 哈尔滨工业大学（威海） 纸基电喷雾离子迁移谱分析方法
CN102636553A (zh) * 2012-03-23 2012-08-15 哈尔滨工业大学（威海） 纸基电喷雾离子迁移谱分析方法
CN102683151A (zh) * 2012-05-15 2012-09-19 中国科学院合肥物质科学研究院 一种选择控制反应离子的化学电离质谱仪
CN102723254A (zh) * 2012-06-20 2012-10-10 清华大学 平板型高场非对称波形离子迁移谱仪的聚焦装置及方法
CN105122051A (zh) * 2013-04-15 2015-12-02 株式会社日立高新技术 分析系统
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US9916972B2 (en) 2013-06-20 2018-03-13 University Of Helsinki Method and device for ionizing particles of a sample gas flow
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US10697944B2 (en) 2014-07-07 2020-06-30 Nanotech Analysis S.R.L. Portable electronic system for the analysis of time-variable gaseous flows
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CN106168614A (zh) * 2015-05-22 2016-11-30 株式会社岛津制作所 放电离子化检测器
CN106168614B (zh) * 2015-05-22 2017-12-19 株式会社岛津制作所 放电离子化检测器
CN108603860A (zh) * 2016-03-04 2018-09-28 株式会社日立高新技术 具备离子迁移率分离部的分析装置
CN108603860B (zh) * 2016-03-04 2020-12-15 株式会社日立高新技术 具备离子迁移率分离部的分析装置
CN107357835B (zh) * 2017-06-22 2020-11-03 电子科技大学 一种基于主题模型和遗忘规律的兴趣预测挖掘方法及系统
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Publication number Publication date
CA2444257A1 (en) 2002-10-24
EP1387724A1 (en) 2004-02-11
JP2004529467A (ja) 2004-09-24
JP4063676B2 (ja) 2008-03-19
IL158386A0 (en) 2004-05-12
AU2002257177B2 (en) 2004-11-25
EP1387724A4 (en) 2006-03-15
WO2002083276A1 (en) 2002-10-24

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