CN1585666A - 用于电喷雾增强的高电场非对称离子淌度光谱测定仪的方法和装置 - Google Patents

用于电喷雾增强的高电场非对称离子淌度光谱测定仪的方法和装置 Download PDF

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Publication number
CN1585666A
CN1585666A CN02812130.9A CN02812130A CN1585666A CN 1585666 A CN1585666 A CN 1585666A CN 02812130 A CN02812130 A CN 02812130A CN 1585666 A CN1585666 A CN 1585666A
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China
Prior art keywords
ion
electrode
filter
flow path
electric field
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English (en)
Chinese (zh)
Inventor
拉安安·A·米勒
欧金琼·G·纳泽罗
加里·A·埃斯曼
埃吉尼·克里洛维
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Charles Stark Draper Laboratory Inc
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Charles Stark Draper Laboratory Inc
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Priority claimed from US10/123,030 external-priority patent/US6690004B2/en
Application filed by Charles Stark Draper Laboratory Inc filed Critical Charles Stark Draper Laboratory Inc
Publication of CN1585666A publication Critical patent/CN1585666A/zh
Pending legal-status Critical Current

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    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/10Ion sources; Ion guns
    • H01J49/16Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165Electrospray ionisation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622Ion mobility spectrometry
    • G01N27/624Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Plasma & Fusion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
CN02812130.9A 2001-04-17 2002-04-17 用于电喷雾增强的高电场非对称离子淌度光谱测定仪的方法和装置 Pending CN1585666A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US83649501A 2001-04-17 2001-04-17
US09/836,495 2001-04-17
US4097402A 2002-01-07 2002-01-07
US10/040,974 2002-01-07
US10/123,030 US6690004B2 (en) 1999-07-21 2002-04-12 Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
US10/123,030 2002-04-12

Publications (1)

Publication Number Publication Date
CN1585666A true CN1585666A (zh) 2005-02-23

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Application Number Title Priority Date Filing Date
CN02812130.9A Pending CN1585666A (zh) 2001-04-17 2002-04-17 用于电喷雾增强的高电场非对称离子淌度光谱测定仪的方法和装置

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EP (1) EP1387724A4 (ja)
JP (1) JP4063676B2 (ja)
CN (1) CN1585666A (ja)
AU (1) AU2002257177B2 (ja)
CA (1) CA2444257A1 (ja)
IL (1) IL158386A0 (ja)
WO (1) WO2002083276A1 (ja)

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CN101082594B (zh) * 2007-07-06 2010-12-15 清华大学 物质成分测定装置
CN102237249A (zh) * 2010-04-30 2011-11-09 安捷伦科技有限公司 适于在大气压下操作的离子源的质谱仪用输入端口
CN102478545A (zh) * 2010-11-30 2012-05-30 中国科学院大连化学物理研究所 一种平板式差分式离子迁移谱
CN102479664A (zh) * 2010-11-30 2012-05-30 中国科学院大连化学物理研究所 一种平板式离子迁移谱
CN102636553A (zh) * 2012-03-23 2012-08-15 哈尔滨工业大学(威海) 纸基电喷雾离子迁移谱分析方法
CN101738417B (zh) * 2009-12-08 2012-09-05 清华大学 基于冷场电子检测生化物质的芯片及检测方法
CN102683151A (zh) * 2012-05-15 2012-09-19 中国科学院合肥物质科学研究院 一种选择控制反应离子的化学电离质谱仪
CN102723254A (zh) * 2012-06-20 2012-10-10 清华大学 平板型高场非对称波形离子迁移谱仪的聚焦装置及方法
CN103163206A (zh) * 2011-12-19 2013-06-19 中国科学院大连化学物理研究所 一种复合电离源差分式离子迁移谱
CN101680857B (zh) * 2007-05-01 2015-06-10 史密斯探测-沃特福特有限公司 包括用于滤波的间隔电极的离子迁移率光谱仪
CN105122051A (zh) * 2013-04-15 2015-12-02 株式会社日立高新技术 分析系统
CN105308715A (zh) * 2013-06-20 2016-02-03 赫尔辛基大学 用于对样品气体流的粒子离子化的方法和装置
CN105874331A (zh) * 2013-12-31 2016-08-17 Dh科技发展私人贸易有限公司 使用高效离子导向器的真空dms
CN106168614A (zh) * 2015-05-22 2016-11-30 株式会社岛津制作所 放电离子化检测器
CN106885838A (zh) * 2007-02-05 2017-06-23 卓漂仪谱公司 离子迁移谱仪与方法
CN107357835A (zh) * 2017-06-22 2017-11-17 电子科技大学 一种基于主题模型和遗忘规律的兴趣预测挖掘方法及系统
CN108603860A (zh) * 2016-03-04 2018-09-28 株式会社日立高新技术 具备离子迁移率分离部的分析装置
CN108760637A (zh) * 2018-07-13 2018-11-06 金华职业技术学院 一种研究分子光异构化的装置
CN109270155A (zh) * 2011-12-28 2019-01-25 英国质谱有限公司 用于液相样品的快速蒸发电离的系统和方法
CN110006985A (zh) * 2018-01-04 2019-07-12 株式会社理光 离子检测装置及其制造方法、faims系统
CN106687808B (zh) * 2014-07-07 2019-08-20 纳米技术分析责任有限公司 用于分析时变气流的便携式电子系统
CN110596401A (zh) * 2019-09-11 2019-12-20 宁波盘福生物科技有限公司 用于蛋白质检测的高场不对称波形离子淌度装置及方法

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US6690004B2 (en) 1999-07-21 2004-02-10 The Charles Stark Draper Laboratory, Inc. Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
US7098449B1 (en) 1999-07-21 2006-08-29 The Charles Stark Draper Laboratory, Inc. Spectrometer chip assembly
US7129482B2 (en) 1999-07-21 2006-10-31 Sionex Corporation Explosives detection using differential ion mobility spectrometry
US7057168B2 (en) 1999-07-21 2006-06-06 Sionex Corporation Systems for differential ion mobility analysis
US6806463B2 (en) 1999-07-21 2004-10-19 The Charles Stark Draper Laboratory, Inc. Micromachined field asymmetric ion mobility filter and detection system
US7148477B2 (en) 1999-07-21 2006-12-12 Sionex Corporation System for trajectory-based ion species identification
US7091481B2 (en) 2001-08-08 2006-08-15 Sionex Corporation Method and apparatus for plasma generation
US6727496B2 (en) 2001-08-14 2004-04-27 Sionex Corporation Pancake spectrometer
US6998608B2 (en) * 2002-02-08 2006-02-14 Ionalytics Corporation FAIMS with non-destructive detection of selectively transmitted ions
US7122794B1 (en) 2002-02-21 2006-10-17 Sionex Corporation Systems and methods for ion mobility control
AU2003298597A1 (en) 2002-10-12 2004-05-25 Sionex Corporation NOx MONITOR USING DIFFERENTIAL MOBILITY SPECTROMETRY
WO2004114347A2 (en) * 2003-06-20 2004-12-29 Brigham Young University Single device for ion mobility and ion trap mass spectrometry
US7223970B2 (en) 2003-09-17 2007-05-29 Sionex Corporation Solid-state gas flow generator and related systems, applications, and methods
US7227134B2 (en) 2003-11-25 2007-06-05 Sionex Corporation Mobility based apparatus and methods using dispersion characteristics, sample fragmentation, and/or pressure control to improve analysis of a sample
WO2005074584A2 (en) * 2004-02-02 2005-08-18 Sionex Corporation Compact sample analysis systems and related methods using combined chromatography and mobility spectrometry techniques
US6967326B2 (en) * 2004-02-27 2005-11-22 Lucent Technologies Inc. Mass spectrometers on wafer-substrates
US8440968B2 (en) 2005-02-14 2013-05-14 Micromass Uk Limited Ion-mobility analyser
GB0503010D0 (en) * 2005-02-14 2005-03-16 Micromass Ltd Mass spectrometer
JP5219274B2 (ja) * 2005-04-01 2013-06-26 マイクロマス ユーケー リミテッド 質量分析計
WO2006127974A1 (en) * 2005-05-24 2006-11-30 Sionex Corporation Combined mass and differential mobility spectrometry
PL1971855T3 (pl) * 2006-01-10 2018-10-31 Smiths Detection-Watford Limited Urządzenie i sposób selekcji jonów
US8217344B2 (en) * 2007-02-01 2012-07-10 Dh Technologies Development Pte. Ltd. Differential mobility spectrometer pre-filter assembly for a mass spectrometer
US7863562B2 (en) * 2007-06-22 2011-01-04 Shimadzu Corporation Method and apparatus for digital differential ion mobility separation
WO2013080004A1 (en) * 2011-11-29 2013-06-06 Dh Technologies Development Pte. Ltd. Differential mobility spectrometer and methods thereof
JP6926544B2 (ja) * 2016-08-05 2021-08-25 株式会社リコー 洗浄用空気作成装置及び計測システム
GB2566326A (en) * 2017-09-11 2019-03-13 Owlstone Inc Ion mobility filter
CN109884157B (zh) * 2017-12-06 2021-06-15 中国科学院大连化学物理研究所 一种新型正负离子快速切换的离子探测器
GB202304891D0 (en) * 2023-03-31 2023-05-17 Univ Liverpool Apparatus and method

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CN106885838A (zh) * 2007-02-05 2017-06-23 卓漂仪谱公司 离子迁移谱仪与方法
CN101680857B (zh) * 2007-05-01 2015-06-10 史密斯探测-沃特福特有限公司 包括用于滤波的间隔电极的离子迁移率光谱仪
CN101082594B (zh) * 2007-07-06 2010-12-15 清华大学 物质成分测定装置
CN101738417B (zh) * 2009-12-08 2012-09-05 清华大学 基于冷场电子检测生化物质的芯片及检测方法
CN102237249A (zh) * 2010-04-30 2011-11-09 安捷伦科技有限公司 适于在大气压下操作的离子源的质谱仪用输入端口
CN102237249B (zh) * 2010-04-30 2016-08-17 安捷伦科技有限公司 适于在大气压下操作的离子源的质谱仪用输入端口
CN102478545A (zh) * 2010-11-30 2012-05-30 中国科学院大连化学物理研究所 一种平板式差分式离子迁移谱
CN102479664A (zh) * 2010-11-30 2012-05-30 中国科学院大连化学物理研究所 一种平板式离子迁移谱
CN103163206A (zh) * 2011-12-19 2013-06-19 中国科学院大连化学物理研究所 一种复合电离源差分式离子迁移谱
CN109270155A (zh) * 2011-12-28 2019-01-25 英国质谱有限公司 用于液相样品的快速蒸发电离的系统和方法
CN109270155B (zh) * 2011-12-28 2021-09-10 英国质谱有限公司 用于液相样品的快速蒸发电离的系统和方法
CN102636553B (zh) * 2012-03-23 2014-05-28 哈尔滨工业大学(威海) 纸基电喷雾离子迁移谱分析方法
CN102636553A (zh) * 2012-03-23 2012-08-15 哈尔滨工业大学(威海) 纸基电喷雾离子迁移谱分析方法
CN102683151A (zh) * 2012-05-15 2012-09-19 中国科学院合肥物质科学研究院 一种选择控制反应离子的化学电离质谱仪
CN102723254A (zh) * 2012-06-20 2012-10-10 清华大学 平板型高场非对称波形离子迁移谱仪的聚焦装置及方法
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US9916972B2 (en) 2013-06-20 2018-03-13 University Of Helsinki Method and device for ionizing particles of a sample gas flow
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US10697944B2 (en) 2014-07-07 2020-06-30 Nanotech Analysis S.R.L. Portable electronic system for the analysis of time-variable gaseous flows
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CN106168614A (zh) * 2015-05-22 2016-11-30 株式会社岛津制作所 放电离子化检测器
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CN108603860A (zh) * 2016-03-04 2018-09-28 株式会社日立高新技术 具备离子迁移率分离部的分析装置
CN108603860B (zh) * 2016-03-04 2020-12-15 株式会社日立高新技术 具备离子迁移率分离部的分析装置
CN107357835B (zh) * 2017-06-22 2020-11-03 电子科技大学 一种基于主题模型和遗忘规律的兴趣预测挖掘方法及系统
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Publication number Publication date
CA2444257A1 (en) 2002-10-24
EP1387724A1 (en) 2004-02-11
JP2004529467A (ja) 2004-09-24
JP4063676B2 (ja) 2008-03-19
IL158386A0 (en) 2004-05-12
AU2002257177B2 (en) 2004-11-25
EP1387724A4 (en) 2006-03-15
WO2002083276A1 (en) 2002-10-24

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