AU2002250262B9 - Methods, kits and compositions of combination oligomers - Google Patents

Methods, kits and compositions of combination oligomers Download PDF

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Publication number
AU2002250262B9
AU2002250262B9 AU2002250262A AU2002250262A AU2002250262B9 AU 2002250262 B9 AU2002250262 B9 AU 2002250262B9 AU 2002250262 A AU2002250262 A AU 2002250262A AU 2002250262 A AU2002250262 A AU 2002250262A AU 2002250262 B9 AU2002250262 B9 AU 2002250262B9
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AU
Australia
Prior art keywords
oligomer
combination
linker
amino acid
gly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002250262A
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English (en)
Other versions
AU2002250262B2 (en
AU2002250262A1 (en
Inventor
James M. Coull
Theresa M. Creasey
Mark J. Fiandaca
Jens J. Hyldig-Nielsen
Mark D. Kristjanson
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Boston Probes Inc
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Boston Probes Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Probes Inc filed Critical Boston Probes Inc
Publication of AU2002250262A1 publication Critical patent/AU2002250262A1/en
Publication of AU2002250262B2 publication Critical patent/AU2002250262B2/en
Application granted granted Critical
Publication of AU2002250262B9 publication Critical patent/AU2002250262B9/en
Priority to AU2007200335A priority Critical patent/AU2007200335B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B20/00Methods specially adapted for identifying library members
    • C40B20/04Identifying library members by means of a tag, label, or other readable or detectable entity associated with the library members, e.g. decoding processes
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/06Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11Compounds covalently bound to a solid support
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Sealing Material Composition (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Electric Connection Of Electric Components To Printed Circuits (AREA)
  • Prostheses (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
AU2002250262A 2001-03-09 2002-03-09 Methods, kits and compositions of combination oligomers Ceased AU2002250262B9 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2007200335A AU2007200335B2 (en) 2001-03-09 2007-01-25 Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27454701P 2001-03-09 2001-03-09
US60/274,547 2001-03-09
PCT/US2002/007050 WO2002072865A2 (en) 2001-03-09 2002-03-09 Methods, kits and compositions of combination oligomers

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2007200335A Division AU2007200335B2 (en) 2001-03-09 2007-01-25 Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation

Publications (3)

Publication Number Publication Date
AU2002250262A1 AU2002250262A1 (en) 2003-03-20
AU2002250262B2 AU2002250262B2 (en) 2006-10-26
AU2002250262B9 true AU2002250262B9 (en) 2006-11-30

Family

ID=23048654

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002250262A Ceased AU2002250262B9 (en) 2001-03-09 2002-03-09 Methods, kits and compositions of combination oligomers

Country Status (9)

Country Link
US (9) US7256275B2 (enExample)
EP (2) EP1412517B1 (enExample)
JP (2) JP4408628B2 (enExample)
AT (2) ATE496139T1 (enExample)
AU (1) AU2002250262B9 (enExample)
CA (1) CA2439750A1 (enExample)
DE (2) DE60216468T2 (enExample)
DK (1) DK1412517T3 (enExample)
WO (1) WO2002072865A2 (enExample)

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EP1575990B1 (en) 2002-09-08 2009-11-18 Applera Corporation Solid phase bound PNA-dimers and their synthesis
WO2004074447A2 (en) * 2003-02-18 2004-09-02 Applera Corporation Compositions and methods for multiplex analysis of polynucleotides
EP1674581A1 (en) * 2004-12-21 2006-06-28 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Twin probes, a tool for the detection of SNPs
US7892737B2 (en) * 2005-06-30 2011-02-22 Life Technologies Corporation Compositions, kits and methods pertaining to stability modulation of PNA oligomer/nucleic acid complexes
GB2433591A (en) * 2005-12-20 2007-06-27 Sharp Kk Method for functionalising a hydrophobic substrate
GB2433505A (en) * 2005-12-20 2007-06-27 Sharp Kk Capture agents for binding a ligand
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US9677123B2 (en) * 2006-03-15 2017-06-13 Siemens Healthcare Diagnostics Inc. Degenerate nucleobase analogs
CN101421420B (zh) * 2006-08-08 2015-03-11 爱科来株式会社 突变的检测方法及用于该方法的试剂盒
WO2008039367A1 (en) * 2006-09-22 2008-04-03 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Synthesis of trans-tert-butyl-2-aminocyclopentylcarbamate
GB0718255D0 (en) * 2007-09-19 2007-10-31 Univ Edinburgh Nucleobase characterisation
WO2010031002A1 (en) * 2008-09-14 2010-03-18 Incitor, Llc Nanoscale molecule synthesis
EP2553123B1 (en) * 2010-03-26 2016-08-24 Integrated DNA Technologies, Inc. Methods for enhancing nucleic acid hybridization
US9506057B2 (en) 2010-03-26 2016-11-29 Integrated Dna Technologies, Inc. Modifications for antisense compounds
EP2614149B1 (en) 2010-09-07 2015-04-08 Integrated Dna Technologies, Inc. Modifications for antisense compounds
EP2691543B1 (en) * 2011-03-29 2017-11-01 Seegene, Inc. Detection of target nucleic acid sequence by pto cleavage and extension-dependent cleavage
WO2013103146A1 (ja) * 2012-01-07 2013-07-11 株式会社ボナック アミノ酸骨格を有する一本鎖核酸分子
CA2864523C (en) * 2012-03-05 2019-02-05 Seegene, Inc. Detection of nucleotide variation on target nucleic acid sequence by pto cleavage and extension assay
CN109810977A (zh) 2012-05-26 2019-05-28 株式会社博纳克 具有递送功能的基因表达调控用单链核酸分子
WO2014021680A1 (ko) * 2012-08-02 2014-02-06 (주)바이오니아 신규 아조화합물, 이의 이용 및 이의제조방법
GB201316644D0 (en) * 2013-09-19 2013-11-06 Kymab Ltd Expression vector production & High-Throughput cell screening
US10612020B2 (en) 2013-12-26 2020-04-07 Tokyo Medical University Artificial mimic miRNA for controlling gene expression, and use of same
WO2015099187A1 (ja) 2013-12-27 2015-07-02 株式会社ボナック 遺伝子発現制御のための人工マッチ型miRNAおよびその用途
US11027023B2 (en) 2014-12-27 2021-06-08 Bonac Corporation Natural type miRNA for controlling gene expression, and use of same
US11142769B2 (en) 2015-03-27 2021-10-12 Bonac Corporation Single-stranded nucleic acid molecule having delivery function and gene expression regulating ability
EP3416976A2 (en) 2016-02-16 2018-12-26 Yale University Compositions for enhancing targeted gene editing and methods of use thereof
US20200113821A1 (en) 2017-04-04 2020-04-16 Yale University Compositions and methods for in utero delivery
KR102403904B1 (ko) * 2019-12-24 2022-06-02 주식회사 시선바이오머티리얼스 용액공정상 pna 올리고머의 제조방법
CN116438456A (zh) * 2020-09-11 2023-07-14 格里姆普斯生物股份有限公司 用于疾病检测/诊断、分期、监测和治疗的离体蛋白酶活性检测
CN113322523B (zh) * 2021-06-17 2024-03-19 翌圣生物科技(上海)股份有限公司 Rna快速建库方法及其应用

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Also Published As

Publication number Publication date
US7605253B2 (en) 2009-10-20
EP1412517A2 (en) 2004-04-28
US20080085837A1 (en) 2008-04-10
CA2439750A1 (en) 2002-09-19
AU2002250262B2 (en) 2006-10-26
EP1748078B1 (en) 2011-01-19
WO2002072865A2 (en) 2002-09-19
US20070105145A1 (en) 2007-05-10
EP1412517B1 (en) 2006-11-29
US20080269074A1 (en) 2008-10-30
DE60216468T2 (de) 2007-09-27
WO2002072865A3 (en) 2003-11-27
DE60239020D1 (de) 2011-03-03
US7256275B2 (en) 2007-08-14
US20030077608A1 (en) 2003-04-24
EP1748078A2 (en) 2007-01-31
EP1748078A3 (en) 2007-02-28
US20080220987A1 (en) 2008-09-11
US20080125332A1 (en) 2008-05-29
JP2004524032A (ja) 2004-08-12
US7851155B2 (en) 2010-12-14
EP1412517A4 (en) 2004-07-07
US20080206747A1 (en) 2008-08-28
JP4408628B2 (ja) 2010-02-03
US7674585B2 (en) 2010-03-09
US7638279B2 (en) 2009-12-29
US7745126B2 (en) 2010-06-29
DE60216468D1 (de) 2007-01-11
DK1412517T3 (da) 2007-03-05
ATE346950T1 (de) 2006-12-15
US7884053B2 (en) 2011-02-08
US20090163381A1 (en) 2009-06-25
US7566420B1 (en) 2009-07-28
JP2007209346A (ja) 2007-08-23
ATE496139T1 (de) 2011-02-15

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