AU2001290524A1 - Soluble zcytor 11 cytokine receptors - Google Patents

Soluble zcytor 11 cytokine receptors

Info

Publication number
AU2001290524A1
AU2001290524A1 AU2001290524A AU9052401A AU2001290524A1 AU 2001290524 A1 AU2001290524 A1 AU 2001290524A1 AU 2001290524 A AU2001290524 A AU 2001290524A AU 9052401 A AU9052401 A AU 9052401A AU 2001290524 A1 AU2001290524 A1 AU 2001290524A1
Authority
AU
Australia
Prior art keywords
cytokine receptors
receptor
antagonist
seq
soluble zcytor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001290524A
Other languages
English (en)
Inventor
Wayne R. Kindsvogel
Stavros Topouzis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of AU2001290524A1 publication Critical patent/AU2001290524A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
AU2001290524A 2000-08-08 2001-08-08 Soluble zcytor 11 cytokine receptors Abandoned AU2001290524A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22382700P 2000-08-08 2000-08-08
US60/223,827 2000-08-08
US25087600P 2000-12-01 2000-12-01
US60/250,876 2000-12-01
PCT/US2001/024838 WO2002012345A2 (en) 2000-08-08 2001-08-08 Soluble zcytor 11 cytokine receptors

Publications (1)

Publication Number Publication Date
AU2001290524A1 true AU2001290524A1 (en) 2002-02-18

Family

ID=26918167

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001290524A Abandoned AU2001290524A1 (en) 2000-08-08 2001-08-08 Soluble zcytor 11 cytokine receptors

Country Status (9)

Country Link
US (5) US7045498B2 (de)
EP (2) EP1337636B1 (de)
JP (1) JP5015404B2 (de)
AT (2) ATE342980T1 (de)
AU (1) AU2001290524A1 (de)
CA (1) CA2418950A1 (de)
DE (1) DE60123998T2 (de)
ES (1) ES2381650T3 (de)
WO (1) WO2002012345A2 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965704A (en) * 1997-08-05 1999-10-12 Zymogenetics, Inc. Class two cytokine receptor-11
US6610286B2 (en) 1999-12-23 2003-08-26 Zymogenetics, Inc. Method for treating inflammation using soluble receptors to interleukin-20
AU2001290524A1 (en) * 2000-08-08 2002-02-18 Zymogenetics Inc. Soluble zcytor 11 cytokine receptors
ATE333888T1 (de) 2000-09-15 2006-08-15 Zymogenetics Inc Verwendung eines polypeptids, welches die extrazelluläre domäne von il-20ra und il-20rb enthält, zur behandlung von entzündungen
US7094570B2 (en) 2003-03-11 2006-08-22 Ludwig Institute For Cancer Research Isolated nucleic acid molecules which encode a soluble IL-TIF/IL-22 receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
US7268223B2 (en) 2000-09-22 2007-09-11 Wyeth Isolated nucleic acid molecules which encode a soluble IL-TIF receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
AU2002249948B2 (en) 2001-01-12 2007-08-23 Genetics Institute, Llc Type 2 cytokine receptor and nucleic acids encoding same
AU2002357283B2 (en) 2001-12-17 2007-08-16 Zymogenetics, Inc. Method for treating cervical cancer
EP1575513A4 (de) * 2002-08-16 2007-04-04 Wyeth Corp Zusammensetzungen und verfahren zur behandlung von mit rage zusammenhängenden erkrankungen
JP2007525437A (ja) * 2003-03-24 2007-09-06 ザイモジェネティクス, インコーポレイテッド 抗il−20抗体および結合パートナーならびに炎症において用いる方法
CN1798768B (zh) * 2003-03-24 2013-05-08 津莫吉尼蒂克斯公司 抗il-22ra抗体和结合伴侣及其应用
WO2005052001A2 (en) 2003-11-21 2005-06-09 Zymogenetics, Inc. Anti-il-20 receptor antibodies and binding partners and methods of using in inflammation
AU2005299809B2 (en) 2004-10-22 2010-12-02 Zymogenetics, Inc. Anti-IL-22RA antibodies and binding partners and methods of using in inflammation
WO2006058024A2 (en) * 2004-11-22 2006-06-01 Smith Henry J Cellular receptors used in the treatment of inflammatory disease
JP2008532931A (ja) 2005-02-08 2008-08-21 ザイモジェネティクス, インコーポレイテッド 抗il−20、抗il−22および抗il−22ra抗体ならびに結合パートナー、ならびに炎症における使用法
EP3683230A1 (de) 2005-05-12 2020-07-22 ZymoGenetics, Inc. Zusammensetzungen und verfahren zur modulation von immunsystemreaktionen
US7180469B2 (en) * 2005-06-29 2007-02-20 Cushcraft Corporation System and method for providing antenna radiation pattern control
JP5368301B2 (ja) 2006-06-22 2013-12-18 ノボ・ノルデイスク・エー/エス 可溶性ヘテロ二量体レセプター及びその使用
KR101361355B1 (ko) 2007-06-14 2014-02-12 갈락티카 파마슈티칼스, 인크. Rage 융합 단백질
US9238878B2 (en) 2009-02-17 2016-01-19 Redwood Bioscience, Inc. Aldehyde-tagged protein-based drug carriers and methods of use
CN107496917B (zh) 2010-02-26 2021-06-11 诺沃—诺迪斯克有限公司 包含稳定抗体的组合物
WO2011147921A1 (en) 2010-05-28 2011-12-01 Novo Nordisk A/S Stable multi-dose compositions comprising an antibody and a preservative
AU2012205301B2 (en) 2011-01-14 2017-01-05 Redwood Bioscience, Inc. Aldehyde-tagged immunoglobulin polypeptides and method of use thereof
CN109071634A (zh) 2016-04-26 2018-12-21 R.P.谢勒技术有限责任公司 抗体偶联物及其制备和使用方法
JP7439372B2 (ja) * 2018-06-21 2024-02-28 シャタック ラボ,インコーポレイテッド ヘテロ二量体タンパク質及びその使用
CN117425674A (zh) * 2021-03-02 2024-01-19 丹娜法伯癌症研究院 治疗红细胞疾患的方法

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3654090A (en) * 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies
WO1989004838A1 (en) * 1987-11-25 1989-06-01 Immunex Corporation Interleukin-1 receptors
US4847325A (en) * 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
US5567584A (en) * 1988-01-22 1996-10-22 Zymogenetics, Inc. Methods of using biologically active dimerized polypeptide fusions to detect PDGF
US5116964A (en) * 1989-02-23 1992-05-26 Genentech, Inc. Hybrid immunoglobulins
US5436155A (en) * 1991-12-31 1995-07-25 Arch Development Corporation Isolated DNA encoding a somatostatin receptor
US5789192A (en) 1992-12-10 1998-08-04 Schering Corporation Mammalian receptors for interleukin-10 (IL-10)
CA2258721C (en) * 1996-07-12 2014-09-09 Genentech, Inc. Chimeric heteromultimer adhesins
US5843697A (en) * 1996-07-17 1998-12-01 University Of Medicine And Dentistry Of New Jersey Cells expressing IL-10 receptor and the CRFB4 gene product, an IL-10 receptor accessory protein
US5985614A (en) * 1996-08-30 1999-11-16 Human Genome Sciences, Inc. Polynucleotides encoding interleukin-19
US5945511A (en) * 1997-02-20 1999-08-31 Zymogenetics, Inc. Class II cytokine receptor
JP2001510035A (ja) 1997-07-16 2001-07-31 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド インターロイキン−20
US6486301B1 (en) 1997-07-16 2002-11-26 Human Genome Sciences, Inc. Interleukin-20
US5965704A (en) * 1997-08-05 1999-10-12 Zymogenetics, Inc. Class two cytokine receptor-11
US6020163A (en) * 1997-08-06 2000-02-01 Zymogenetics, Inc. Lipocalin homolog
BR9814904A (pt) 1997-11-26 2000-10-03 Zymogenetics Inc Polinucleotìdeo isolado que codifica um polipeptìdeo, polipeptìdeo isolado, e, anticorpo.
US6576743B1 (en) * 1997-11-26 2003-06-10 Zymogenetics, Inc. Mammalian cytokine-like polypeptide-10
IL137178A0 (en) 1998-01-23 2001-07-24 Immunex Corp Il-18 receptors
CA2323236A1 (en) 1998-03-09 1999-09-16 Schering Corporation Human receptor proteins; related reagents and methods
NZ507435A (en) 1998-03-10 2003-12-19 Genentech Inc Novel polypeptides and nucleic acids with homology to cornichon
US6982320B2 (en) 1998-03-19 2006-01-03 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
AU5203199A (en) 1998-05-26 1999-12-13 Procter & Gamble Company, The Chimeric molecules comprising an extracellular ligand binding domain of a receptor and an ige fc or constant region, and their use in an assay system
DE69911793T2 (de) * 1998-07-28 2004-08-12 Micromet Ag Heterominikörper
CA2339043A1 (en) 1998-09-01 2000-03-09 Genentech, Inc. Further pro polypeptides and sequences thereof
US6472179B2 (en) * 1998-09-25 2002-10-29 Regeneron Pharmaceuticals, Inc. Receptor based antagonists and methods of making and using
BR9914777A (pt) 1998-10-26 2001-07-03 Ludwig Inst Cancer Res Moléculas isoladas de ácido nucléico que codificam os fatores induzìveis por células t (tifs), as proteìnas codificadas e os usos das mesmas
US6274710B1 (en) * 1998-10-26 2001-08-14 Ludwig Institute For Cancer Research Antibodies which specifically bind T Cell inducible factors (TIFs)
EP1141008A1 (de) * 1998-12-31 2001-10-10 Millennium Pharmaceuticals, Inc. Cytokinin klasse ii rezeptor-ähnliche proteine und für diese kodierende nukleinsäuren
DK1177312T3 (da) 1999-04-28 2008-02-25 Genetics Inst Llc Humane GIL-19/AE289-proteiner og polynukleotider kodende derfor
CA2373231A1 (en) 1999-05-19 2000-11-23 Incyte Genomics, Inc. Extracellular signaling molecules
AU5047600A (en) 1999-05-27 2000-12-18 Schering Corporation Mammalian interleukin-10 homologs: il-d110 and il-d210
EP1208195A2 (de) 1999-06-15 2002-05-29 Genentech Inc. Ausgeschiedene und transmembran-polypeptide und dafür kodierende nukleinsäure
AU2883700A (en) 1999-06-23 2001-01-09 Genentech Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
DK1860188T3 (da) 1999-07-07 2011-06-27 Zymogenetics Inc Human cytokin-receptor
AU7573000A (en) * 1999-09-01 2001-03-26 Genentech Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
MXPA02005058A (es) 1999-11-18 2002-11-07 Schering Corp Proteinas de mamiferos receptoras, reactivos y metodos relacionados.
EP1234035B1 (de) * 1999-12-03 2010-02-24 ZymoGenetics, Inc. Menschliches zytokinrezeptor
DK1246846T3 (da) 1999-12-23 2008-12-08 Zymogenetics Inc Oplöselig interleukin-20-receptor
JP2003524415A (ja) 1999-12-23 2003-08-19 ザイモジェネティクス,インコーポレイティド サイトカインzcyto18
US6610286B2 (en) * 1999-12-23 2003-08-26 Zymogenetics, Inc. Method for treating inflammation using soluble receptors to interleukin-20
EP2295078A3 (de) 1999-12-23 2011-03-23 ZymoGenetics, L.L.C. Verfahren zur Behandlung von Entzündungen
NZ523122A (en) 2000-06-22 2004-06-25 Smithkline Beecham Corp Polypeptides and polynucleotides and methods of identifying agonists and antagonists in relation to treatment of diseases
AU2001290524A1 (en) * 2000-08-08 2002-02-18 Zymogenetics Inc. Soluble zcytor 11 cytokine receptors
EP2298789B1 (de) 2000-09-08 2012-03-14 Schering Corporation Gene von Säugetiere, und damit verbundene Reagentien, Methoden
ATE333888T1 (de) * 2000-09-15 2006-08-15 Zymogenetics Inc Verwendung eines polypeptids, welches die extrazelluläre domäne von il-20ra und il-20rb enthält, zur behandlung von entzündungen
US7268223B2 (en) 2000-09-22 2007-09-11 Wyeth Isolated nucleic acid molecules which encode a soluble IL-TIF receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
US20030022827A1 (en) * 2000-09-25 2003-01-30 Bertram Weiss Three new members of the cytokine receptor family class 2
AU2002249948B2 (en) 2001-01-12 2007-08-23 Genetics Institute, Llc Type 2 cytokine receptor and nucleic acids encoding same
WO2002058724A2 (en) 2001-01-26 2002-08-01 Eli Lilly And Company Use of lp82 to treat body weight disorders
JP2005510451A (ja) 2001-02-23 2005-04-21 ジェネティクス インスティテュート,エルエルシー 炎症性障害を治療するための組成物及び方法
CN1503677A (zh) 2001-02-28 2004-06-09 用lp82治疗造血障碍
US6875845B2 (en) * 2001-03-02 2005-04-05 Zymogenetics, Inc. Mouse cytokine receptor
AU2002245652A1 (en) 2001-03-09 2002-09-24 Zymogenetics, Inc. Soluble heterodimeric cytokine receptor
US20040086908A1 (en) * 2002-03-07 2004-05-06 Chandrasekher Yasmin A. Soluble heterodimeric cytokine receptor
AU2002252460A1 (en) 2001-03-27 2002-10-08 Zymogenetics, Inc. Human cytokine receptor
US20040204351A1 (en) 2001-10-22 2004-10-14 Rowlinson Scott William Soluble proteins that inhibit cytokine signal transduction pathways
DE10154579A1 (de) 2001-11-07 2003-05-28 Medigene Ag Topikale Verwendung von Cytokinen und Chemokinen zur Behandlung von viralen oder mykotischen Hauterkrankungen oder Tumorerkrankungen
AU2002357283B2 (en) 2001-12-17 2007-08-16 Zymogenetics, Inc. Method for treating cervical cancer
US20040236075A1 (en) * 2002-07-24 2004-11-25 Laure Dumoutier Novel glass II cytokine receptors, and uses thereof
JP2007525437A (ja) 2003-03-24 2007-09-06 ザイモジェネティクス, インコーポレイテッド 抗il−20抗体および結合パートナーならびに炎症において用いる方法
WO2005052001A2 (en) * 2003-11-21 2005-06-09 Zymogenetics, Inc. Anti-il-20 receptor antibodies and binding partners and methods of using in inflammation
AU2005299809B2 (en) * 2004-10-22 2010-12-02 Zymogenetics, Inc. Anti-IL-22RA antibodies and binding partners and methods of using in inflammation

Also Published As

Publication number Publication date
EP2177616B1 (de) 2012-02-29
CA2418950A1 (en) 2002-02-14
DE60123998T2 (de) 2007-09-06
US7045498B2 (en) 2006-05-16
US20030157096A1 (en) 2003-08-21
WO2002012345A2 (en) 2002-02-14
EP1337636A2 (de) 2003-08-27
ATE547525T1 (de) 2012-03-15
JP5015404B2 (ja) 2012-08-29
US8287866B2 (en) 2012-10-16
EP2177616A1 (de) 2010-04-21
DE60123998D1 (de) 2006-11-30
WO2002012345A3 (en) 2003-06-12
US20060068471A1 (en) 2006-03-30
ES2381650T3 (es) 2012-05-30
US20110081344A1 (en) 2011-04-07
US20130028894A1 (en) 2013-01-31
JP2004505641A (ja) 2004-02-26
EP1337636B1 (de) 2006-10-18
ATE342980T1 (de) 2006-11-15
US20100047168A1 (en) 2010-02-25

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