AR010333A1 - Una muteina ob, una secuencia de adn, un vector de expresion una celula hospedadora procariota o de mamifero, un baculovirus recombinante, una celulahospedadora, un metodo para la produccion de una muteina ob, una composicion farmaceutica, el uso de una proteina ob para la preparacion de una composi - Google Patents
Una muteina ob, una secuencia de adn, un vector de expresion una celula hospedadora procariota o de mamifero, un baculovirus recombinante, una celulahospedadora, un metodo para la produccion de una muteina ob, una composicion farmaceutica, el uso de una proteina ob para la preparacion de una composiInfo
- Publication number
- AR010333A1 AR010333A1 ARP970105715A AR010333A1 AR 010333 A1 AR010333 A1 AR 010333A1 AR P970105715 A ARP970105715 A AR P970105715A AR 010333 A1 AR010333 A1 AR 010333A1
- Authority
- AR
- Argentina
- Prior art keywords
- mutein
- pharmaceutical composition
- cell
- production
- dna sequence
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Obesity (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Child & Adolescent Psychology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Una muteína ob que comprende actividad normal de union a receptor en un ensayo de competicion y que es incapaz de trasnducir senales biologicas, unasecuencia de ADN, un vector de expresion, una célula hospedadora porcariota o de mamífero, un baculovirus recombinante, una célula hospedadora, un metodopara la produccion de una muteína ob, una composicion farmacéutica, el uso de una proteína ob para la preparacion de una composicion farmacéutica,anticuerpos poli y monoclonales.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96119606 | 1996-12-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR010333A1 true AR010333A1 (es) | 2000-06-07 |
Family
ID=8223476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970105715 AR010333A1 (es) | 1996-12-06 | 1997-12-04 | Una muteina ob, una secuencia de adn, un vector de expresion una celula hospedadora procariota o de mamifero, un baculovirus recombinante, una celulahospedadora, un metodo para la produccion de una muteina ob, una composicion farmaceutica, el uso de una proteina ob para la preparacion de una composi |
Country Status (8)
| Country | Link |
|---|---|
| AR (1) | AR010333A1 (es) |
| AU (1) | AU5654998A (es) |
| CO (1) | CO4930295A1 (es) |
| HR (1) | HRP970654A2 (es) |
| MA (1) | MA24411A1 (es) |
| PE (1) | PE20399A1 (es) |
| WO (1) | WO1998024896A2 (es) |
| ZA (1) | ZA9710832B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6777388B1 (en) | 1998-08-21 | 2004-08-17 | Clf Medical Technology Acceleration Program, Inc. | Leptin-related peptides |
| US7208572B2 (en) | 1998-08-21 | 2007-04-24 | Albany Medical College | Leptin-related peptides |
| US6420339B1 (en) * | 1998-10-14 | 2002-07-16 | Amgen Inc. | Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility |
| US8227408B2 (en) | 2005-09-07 | 2012-07-24 | Neurotez, Inc. | Leptin as an anti-amyloidogenic biologic and methods for delaying the onset and reducing Alzheimer's disease-like pathology |
| KR20110028457A (ko) | 2008-05-21 | 2011-03-18 | 뉴로테즈 인코포레이티드 | 신경섬유 매듭과 연관된 신경변성 장애를 치료하는 방법 |
| CA2742600A1 (en) | 2008-11-04 | 2010-05-14 | Nikolaos Tezapsidis | Leptin compositions and methods for treating progressive cognitive function disorders resulting from accumulation of neurofibrillary tangles and amlyoid beta |
| PT2621519T (pt) | 2010-09-28 | 2017-10-04 | Aegerion Pharmaceuticals Inc | Polipéptido de fusão de leptina-abd com duração de ação melhorada |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1259923A (en) * | 1983-08-17 | 1989-09-26 | Roger Aston | Physiologically active compositions |
| US6309853B1 (en) * | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| EP0725079A1 (en) * | 1995-01-31 | 1996-08-07 | Eli Lilly And Company | Anti-obesity proteins |
| GB9509164D0 (en) * | 1995-05-05 | 1995-06-28 | Smithkline Beecham Plc | Novel compounds |
-
1997
- 1997-11-22 AU AU56549/98A patent/AU5654998A/en not_active Abandoned
- 1997-11-22 WO PCT/EP1997/006541 patent/WO1998024896A2/en active Application Filing
- 1997-12-01 MA MA24881A patent/MA24411A1/fr unknown
- 1997-12-02 PE PE00108697A patent/PE20399A1/es not_active Application Discontinuation
- 1997-12-02 ZA ZA9710832A patent/ZA9710832B/xx unknown
- 1997-12-03 HR HRP970654 patent/HRP970654A2/hr not_active Application Discontinuation
- 1997-12-04 CO CO97071061A patent/CO4930295A1/es unknown
- 1997-12-04 AR ARP970105715 patent/AR010333A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP970654A2 (en) | 1998-10-31 |
| CO4930295A1 (es) | 2000-06-27 |
| WO1998024896A2 (en) | 1998-06-11 |
| PE20399A1 (es) | 1999-03-05 |
| WO1998024896A3 (en) | 1998-10-01 |
| MA24411A1 (fr) | 1998-07-01 |
| AU5654998A (en) | 1998-06-29 |
| ZA9710832B (en) | 1998-06-08 |
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