AU2001274276B2 - Therapeutic combinations of fatty acids - Google Patents

Therapeutic combinations of fatty acids Download PDF

Info

Publication number
AU2001274276B2
AU2001274276B2 AU2001274276A AU2001274276A AU2001274276B2 AU 2001274276 B2 AU2001274276 B2 AU 2001274276B2 AU 2001274276 A AU2001274276 A AU 2001274276A AU 2001274276 A AU2001274276 A AU 2001274276A AU 2001274276 B2 AU2001274276 B2 AU 2001274276B2
Authority
AU
Australia
Prior art keywords
epa
precursor
use according
disease
fatty acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2001274276A
Other languages
English (en)
Other versions
AU2001274276A1 (en
Inventor
David Frederick Horrobin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laxdale Ltd
Original Assignee
Laxdale Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laxdale Ltd filed Critical Laxdale Ltd
Publication of AU2001274276A1 publication Critical patent/AU2001274276A1/en
Application granted granted Critical
Publication of AU2001274276B2 publication Critical patent/AU2001274276B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001274276A 2000-06-29 2001-06-20 Therapeutic combinations of fatty acids Ceased AU2001274276B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0016045.7 2000-06-29
GBGB0016045.7A GB0016045D0 (en) 2000-06-29 2000-06-29 Therapeutic combinations of fatty acids
PCT/GB2001/002717 WO2002002105A1 (en) 2000-06-29 2001-06-20 Therapeutic combinations of fatty acids

Publications (2)

Publication Number Publication Date
AU2001274276A1 AU2001274276A1 (en) 2002-04-11
AU2001274276B2 true AU2001274276B2 (en) 2006-03-30

Family

ID=9894724

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001274276A Ceased AU2001274276B2 (en) 2000-06-29 2001-06-20 Therapeutic combinations of fatty acids
AU7427601A Pending AU7427601A (en) 2000-06-29 2001-06-20 Therapeutic combinations of fatty acids

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU7427601A Pending AU7427601A (en) 2000-06-29 2001-06-20 Therapeutic combinations of fatty acids

Country Status (32)

Country Link
US (1) US6479544B1 (enExample)
EP (1) EP1296670B1 (enExample)
JP (1) JP2004501969A (enExample)
KR (1) KR20030016306A (enExample)
CN (1) CN100469363C (enExample)
AT (1) ATE315388T1 (enExample)
AU (2) AU2001274276B2 (enExample)
BR (1) BR0112073A (enExample)
CA (1) CA2411368C (enExample)
CZ (1) CZ20024173A3 (enExample)
DE (1) DE60116625T2 (enExample)
DK (1) DK1296670T3 (enExample)
EE (1) EE05148B1 (enExample)
ES (1) ES2256250T3 (enExample)
GB (1) GB0016045D0 (enExample)
HR (1) HRP20030035A2 (enExample)
HU (1) HUP0301107A2 (enExample)
IL (1) IL153458A0 (enExample)
IS (1) IS2226B (enExample)
MX (1) MXPA02012689A (enExample)
MY (1) MY117830A (enExample)
NO (1) NO329868B1 (enExample)
NZ (1) NZ522916A (enExample)
PL (1) PL359185A1 (enExample)
PT (1) PT1296670E (enExample)
RU (1) RU2276975C2 (enExample)
SK (1) SK287209B6 (enExample)
TW (1) TWI285549B (enExample)
UA (1) UA76108C2 (enExample)
WO (1) WO2002002105A1 (enExample)
YU (1) YU99602A (enExample)
ZA (1) ZA200300198B (enExample)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9901809D0 (en) 1999-01-27 1999-03-17 Scarista Limited Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes
DE10006836B4 (de) * 2000-04-18 2005-03-24 Bitec Gmbh Verwendung von Omega-3-Fettsäuren und/oder Verbindungen von Omega-3-Fettsäuren
ITMI20010129A1 (it) 2001-01-25 2002-07-25 Pharmacia & Upjohn Spa Acidi grassi essenziali nella terapia di insufficienza cardiaca e scompenso cardiaco
JP2003048831A (ja) * 2001-08-02 2003-02-21 Suntory Ltd 脳機能の低下に起因する症状あるいは疾患の予防又は改善作用を有する組成物
BR0314710A (pt) 2002-09-27 2005-07-26 Martek Biosciences Corp Terapia profilática com ácido decosahexenóico para pacientes com inflamação subclìnica
DE10254584A1 (de) * 2002-11-22 2004-06-09 HORST HEIRLER PROJEKTE für Ernährung, Medizin, Ökologie Verwendung von mittelkettigen Triglyceriden (MCT) zur ernährungsphysiologischen Optimierung des Fettsäurenspektrums in einem diätetischen Lebensmittel für Diabetiker
GB0311081D0 (en) 2003-05-14 2003-06-18 Btg Internat Limted Treatment of neurodegenerative conditions
FR2856304B1 (fr) * 2003-06-20 2006-03-03 Natural Product Consulting Composition pour la prevention des infections du systeme urinaire
AU2004266480B2 (en) 2003-08-18 2011-03-03 Btg International Limited Treatment of neurodegenerative conditions
US7875291B1 (en) 2003-09-05 2011-01-25 Glu-Pro, Inc. Composition for managing diabetes, obesity, and hyperlipidemia and associated methods
JP4522075B2 (ja) * 2003-10-29 2010-08-11 サントリーホールディングス株式会社 血管の老化に起因する症状あるいは疾患の予防又は改善作用を有する組成物
US20050249823A1 (en) * 2003-11-04 2005-11-10 Murphy Tanya K Methods for the prevention or amelioration of neuropsychiatric and related diseases
WO2005046668A1 (ja) * 2003-11-14 2005-05-26 Mochida Pharmaceutical Co., Ltd. 言語障害予防・治療剤
EP1543735B1 (en) * 2003-12-20 2015-10-07 Nestec S.A. Nutritional composition for wound healing
EP1713463A4 (en) * 2004-01-19 2009-03-18 Martek Biosciences Corp REELIN DYSFUNCTION OR DICTION AND ASSOCIATED TECHNIQUES
EP1629850B2 (en) 2004-08-24 2013-05-22 N.V. Nutricia Nutritional composition comprising indigestible transgalactooligosaccharides and digestible galactose saccharides
JP4993852B2 (ja) 2004-09-17 2012-08-08 サントリーホールディングス株式会社 ストレスに起因する行動異常を伴う症状あるいは疾患の予防又は改善作用を有する組成物
JP2006083136A (ja) * 2004-09-17 2006-03-30 Suntory Ltd ストレスに起因する脳機能の低下およびそれに伴う症状あるいは疾患の予防又は改善作用を有する組成物
US8431165B2 (en) * 2004-12-13 2013-04-30 Swing Aerobics Licensing, Inc. Medicament for treatment of cancer and other diseases
US8092839B2 (en) * 2004-12-13 2012-01-10 Swing Aerobics Licensing, Inc. Medicament for treatment of cancer and other diseases
US20060135610A1 (en) * 2004-12-22 2006-06-22 Bortz Jonathan D Cardiovascular compositions
GB2421909A (en) * 2004-12-23 2006-07-12 Laxdale Ltd Pharmaceutical compositions comprising EPA and methods of use
WO2006077495A1 (en) * 2005-01-24 2006-07-27 Pronova Biocare As Use of a fatty acid composition containing dha for the production of a medical product or a food stuff for the treatment of amyloidos-rerelated diseases
US9006287B2 (en) 2005-02-14 2015-04-14 Suntory Holdings Limited Composition comprising dihomo-γ-linolenic acid (DGLA) as active ingredient
GB0504362D0 (en) 2005-03-02 2005-04-06 Btg Int Ltd Cytokine modulators
JP5967855B2 (ja) * 2005-06-30 2016-08-10 サントリーホールディングス株式会社 日中活動量の低下および/又はうつ症状の改善作用を有する組成物
BRPI0619598A2 (pt) * 2005-12-09 2011-10-11 Drugtech Corp composição de emulsão intravenosa de ácido graxo essencial e métodos de administração da mesma
GB0607946D0 (en) * 2006-04-21 2006-05-31 Minster Res The Ltd Mono and combination therapy
GB0607949D0 (en) * 2006-04-21 2006-05-31 Minster Res The Ltd Mono and combination therapy
KR101578498B1 (ko) * 2006-12-28 2015-12-18 산토리 홀딩스 가부시키가이샤 신경 재생제
WO2009009040A2 (en) * 2007-07-06 2009-01-15 Baum Seth J Fatty acid compositions and methods of use
US8343753B2 (en) * 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
EP3187182B1 (en) 2008-09-02 2021-03-03 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and nicotinic acid and methods of using same
EP2395991B1 (en) 2009-02-10 2013-05-29 Amarin Pharmaceuticals Ireland Limited Use of eicosapentaenoic acid ethyl ester for treating hypertriglyceridemia
AU2010241571B2 (en) 2009-04-29 2014-06-26 Amarin Pharmaceuticals Ireland Limited Stable pharmaceutical composition and methods of using same
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
CN102413825A (zh) 2009-04-29 2012-04-11 阿马里纳股份公司 含有epa和心血管剂的药物组合物以及使用其的方法
WO2010147994A1 (en) 2009-06-15 2010-12-23 Amarin Pharma, Inc. Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy
AU2010298222B2 (en) 2009-09-23 2017-01-05 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same
US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
NZ778131A (en) 2010-11-29 2023-03-31 Amarin Pharmaceuticals Ie Ltd Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
US10383839B2 (en) 2011-06-30 2019-08-20 Johnson & Johnson Vision Care, Inc. Esters for treatment of ocular inflammatory conditions
US8293790B2 (en) 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
US11291643B2 (en) 2011-11-07 2022-04-05 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
EP2775837A4 (en) 2011-11-07 2015-10-28 Amarin Pharmaceuticals Ie Ltd METHODS OF TREATING HYPERTRIGLYCERIDEMIA
SG11201403805WA (en) 2012-01-06 2014-08-28 Omthera Pharmaceuticals Inc Dpa-enriched compositions of omega-3 polyunsaturated fatty acids in free acid form
AU2013207368A1 (en) 2012-01-06 2014-07-24 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering levels of high-sensitivity (hs-CRP) in a subject
TW201347754A (zh) 2012-05-07 2013-12-01 Omthera Pharmaceuticals Inc 史他汀及ω-3脂肪酸之組合物
EP2861227A4 (en) 2012-06-17 2016-01-27 Matinas Biopharma Inc OMEGA-3 PENTAIC ACID COMPOSITIONS AND METHODS OF USE
LT3363433T (lt) 2012-06-29 2021-02-25 Amarin Pharmaceuticals Ireland Limited Širdies ir kraujagyslių sistemos sutrikimų rizikos sumažinimo būdas subjektui, gydomam statinais, panaudojant eikozapentaeno rūgšties etilo esterį
WO2014074552A2 (en) 2012-11-06 2014-05-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising ldl-c levels in a subject on concomitant statin therapy
WO2014089501A1 (en) 2012-12-06 2014-06-12 Matinas Biopharma, Inc. Omega-3 pentaenoic acid compositions and methods of use
US9629820B2 (en) 2012-12-24 2017-04-25 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
US10123986B2 (en) 2012-12-24 2018-11-13 Qualitas Health, Ltd. Eicosapentaenoic acid (EPA) formulations
US20140187633A1 (en) 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
US9814733B2 (en) 2012-12-31 2017-11-14 A,arin Pharmaceuticals Ireland Limited Compositions comprising EPA and obeticholic acid and methods of use thereof
US9452151B2 (en) 2013-02-06 2016-09-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
US20140221676A1 (en) * 2013-02-06 2014-08-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating and/or preventing cardiovascular disease
US9624492B2 (en) 2013-02-13 2017-04-18 Amarin Pharmaceuticals Ireland Limited Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
US9662307B2 (en) 2013-02-19 2017-05-30 The Regents Of The University Of Colorado Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
US9283201B2 (en) 2013-03-14 2016-03-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US20140271841A1 (en) 2013-03-15 2014-09-18 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
US10966968B2 (en) 2013-06-06 2021-04-06 Amarin Pharmaceuticals Ireland Limited Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US20150065572A1 (en) * 2013-09-04 2015-03-05 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing prostate cancer
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
MX372759B (es) 2013-11-05 2020-06-29 Hills Pet Nutrition Inc Composiciones para usarse en mejorar la función renal.
ES2875965T3 (es) 2013-12-04 2021-11-11 Nippon Suisan Kaisha Ltd Aceite microbiano que contiene ácido dihomo-gamma-linolénico y biomasa microbiana que contiene ácido dihomo-gamma-linolénico
AU2015270418B2 (en) 2014-06-04 2020-08-06 Ds Biopharma Limited Pharmaceutical compositions comprising DGLA and use of same
US10561631B2 (en) 2014-06-11 2020-02-18 Amarin Pharmaceuticals Ireland Limited Methods of reducing RLP-C
US10172818B2 (en) 2014-06-16 2019-01-08 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
US10406130B2 (en) 2016-03-15 2019-09-10 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
US10966951B2 (en) 2017-05-19 2021-04-06 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject having reduced kidney function
US11058661B2 (en) 2018-03-02 2021-07-13 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
MA50490A (fr) 2018-09-24 2020-09-02 Amarin Pharmaceuticals Ie Ltd Procédés de réduction du risque d'événements cardiovasculaires chez un sujet
JP2022554020A (ja) 2019-11-12 2022-12-27 アマリン ファーマシューティカルズ アイルランド リミテッド 心房細動および/または心房粗動を患う対象における心血管イベントのリスクを低減する方法
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases
KR20220010415A (ko) * 2020-07-17 2022-01-25 대봉엘에스 주식회사 불포화 지방산을 특정 함량으로 포함하는 유지 조성물 및 이의 용도
AU2022263358A1 (en) 2021-04-21 2023-11-30 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of heart failure

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US551680A (en) * 1895-12-17 Water-tube steam-generator
US4977187A (en) * 1988-06-10 1990-12-11 Efamol Holdings Plc Treating schizophrenia with essential fatty acid compositions
US5198468A (en) * 1987-06-24 1993-03-30 Efamol Holdings Plc Essential fatty acid composition
US5252333A (en) * 1987-04-27 1993-10-12 Scotia Holdings Plc Lithium salt-containing pharmaceutical compositions
EP0711503A2 (en) * 1994-11-14 1996-05-15 Scotia Holdings Plc Milk fortified with GLA and/or DGLA
EP0713653A1 (en) * 1994-11-23 1996-05-29 Scotia Holdings Plc Fortified fruit juice
US5583159A (en) * 1993-01-26 1996-12-10 Scotia Holdings Plc Treatment of internal radiation damage

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526902A (en) * 1983-10-24 1985-07-02 Century Laboratories, Inc. Combined fatty acid composition for treatment or prophylaxis of thrombo-embolic conditions
JPS60132916A (ja) * 1983-12-21 1985-07-16 Nisshin Oil Mills Ltd:The 血栓症予防食品または医薬品
GB8714772D0 (en) * 1987-06-24 1987-07-29 Efamol Ltd Essential fatty acid compositions
US5260067A (en) * 1988-11-16 1993-11-09 Xu Zheng Cytotropic heterogeneous molecular lipids (CHML) and process for preparing the same
JPH04169524A (ja) * 1990-11-01 1992-06-17 Nissei Marine Kogyo Kk 血清脂質改善作用を有する組成物
US5658767A (en) * 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
GB9125602D0 (en) * 1991-12-02 1992-01-29 Efamol Holdings Method of preventing reocclusion of arteries
JPH05163142A (ja) * 1991-12-17 1993-06-29 Tokiwa Yakuhin Kogyo Kk 肝障害の予防または治療用アラキドン酸含有組成物
US5223285A (en) * 1992-03-31 1993-06-29 Abbott Laboratories Nutritional product for pulmonary patients
GB9217781D0 (en) * 1992-08-21 1992-10-07 Efamol Holdings Fatty acid treatment
US5516801A (en) * 1992-08-21 1996-05-14 Scotia Holdings Plc Fatty acid treatment for ectopic calcium deposition
GB9218064D0 (en) * 1992-08-25 1992-10-14 Efamol Holdings Method for the safe intravenous administration of fatty acids
GB9224809D0 (en) * 1992-11-26 1993-01-13 Scotia Holdings Plc Schizophrenia
GB9301629D0 (en) 1993-01-27 1993-03-17 Scotia Holdings Plc Formulations containing unsaturated fatty acids
JPH06271464A (ja) * 1993-03-19 1994-09-27 Tokiwa Yakuhin Kogyo Kk 消化器系障害の予防または治療用アラキドン酸含有組成物
CA2119000A1 (en) * 1993-03-19 1994-09-20 David Frederick Horrobin Formulation for use in smokers
AUPM906594A0 (en) * 1994-10-26 1994-11-17 Peptide Technology Limited Synthetic polyunsaturated fatty acid analogues
GB9617847D0 (en) * 1996-08-27 1996-10-09 Scotia Holdings Plc Fatty acid treatment
PT1039892E (pt) * 1997-02-21 2004-09-30 Abbott Lab Utilizacao de acidos gordos polinsaturados para reducao da incidencia de enterocolite necrotizante
US5993221A (en) * 1997-05-01 1999-11-30 Beth Israel Deaconess Medical Center, Inc. Dietary formulation comprising arachidonic acid and methods of use
CN1212867A (zh) * 1997-09-29 1999-04-07 宋凤亭 防治心脑血管疾病的组合物
DE19757414A1 (de) * 1997-12-23 1999-07-01 Nutricia Nv Fettmischung
AU775421B2 (en) 1998-10-15 2004-07-29 Dsm Ip Assets B.V. Pufa supplements
SE9900941D0 (sv) * 1998-12-23 1999-03-16 Nomet Management Serv Bv Novel retinoic acid derivatives and their use
GB9901809D0 (en) 1999-01-27 1999-03-17 Scarista Limited Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US551680A (en) * 1895-12-17 Water-tube steam-generator
US5252333A (en) * 1987-04-27 1993-10-12 Scotia Holdings Plc Lithium salt-containing pharmaceutical compositions
US5198468A (en) * 1987-06-24 1993-03-30 Efamol Holdings Plc Essential fatty acid composition
US4977187A (en) * 1988-06-10 1990-12-11 Efamol Holdings Plc Treating schizophrenia with essential fatty acid compositions
US5583159A (en) * 1993-01-26 1996-12-10 Scotia Holdings Plc Treatment of internal radiation damage
EP0711503A2 (en) * 1994-11-14 1996-05-15 Scotia Holdings Plc Milk fortified with GLA and/or DGLA
EP0713653A1 (en) * 1994-11-23 1996-05-29 Scotia Holdings Plc Fortified fruit juice

Also Published As

Publication number Publication date
CA2411368C (en) 2009-11-17
RU2276975C2 (ru) 2006-05-27
NO20026093L (no) 2002-12-18
NO20026093D0 (no) 2002-12-18
CN1438884A (zh) 2003-08-27
HK1050486A1 (en) 2003-06-27
ZA200300198B (en) 2004-01-26
EP1296670A1 (en) 2003-04-02
DE60116625T2 (de) 2006-12-14
HUP0301107A2 (hu) 2003-08-28
EE05148B1 (et) 2009-04-15
DE60116625D1 (de) 2006-04-06
MXPA02012689A (es) 2004-04-20
IL153458A0 (en) 2003-07-06
IS6644A (is) 2002-11-29
MY117830A (en) 2004-08-30
TWI285549B (en) 2007-08-21
AU7427601A (en) 2002-01-14
HRP20030035A2 (en) 2003-04-30
CZ20024173A3 (cs) 2003-05-14
ES2256250T3 (es) 2006-07-16
WO2002002105A1 (en) 2002-01-10
PL359185A1 (en) 2004-08-23
YU99602A (sh) 2006-05-25
IS2226B (is) 2007-04-15
ATE315388T1 (de) 2006-02-15
SK18162002A3 (sk) 2003-08-05
EE200200718A (et) 2004-08-16
CA2411368A1 (en) 2002-01-10
NO329868B1 (no) 2011-01-17
SK287209B6 (sk) 2010-03-08
NZ522916A (en) 2004-03-26
CN100469363C (zh) 2009-03-18
US6479544B1 (en) 2002-11-12
PT1296670E (pt) 2006-05-31
UA76108C2 (en) 2006-07-17
KR20030016306A (ko) 2003-02-26
BR0112073A (pt) 2003-05-20
JP2004501969A (ja) 2004-01-22
GB0016045D0 (en) 2000-08-23
EP1296670B1 (en) 2006-01-11
DK1296670T3 (da) 2006-05-08

Similar Documents

Publication Publication Date Title
AU2001274276B2 (en) Therapeutic combinations of fatty acids
AU2001274276A1 (en) Therapeutic combinations of fatty acids
JP2796838B2 (ja) 精神分裂症および/または関連した晩発性運動障害の治療のための薬剤を製造する方法
US7195914B2 (en) Composition and method for treatment of hypertriglyceridemia
JP2005535733A (ja) ドライアイ、マイボーム腺炎及び口内乾燥症の治療用epa及びdha富化オメガ−3補給剤
AU2001286576A1 (en) Composition and method for treatment of hypertriglyceridemia
SK14502003A3 (en) Coenzyme Q and eicosapentaenoic acid
JPH11209279A (ja) 体重減少および肥満処置の方法
WO1998048788A1 (en) Treatment of depression and anxiety using docosahexaenoic acid or natural antioxidants
US6228367B1 (en) Food supplement formulation
HK1050486B (en) Therapeutic combinations of fatty acids
JPH11343236A (ja) 多価不飽和脂肪酸を含有する医薬組成物および健康食品
JP2002234838A (ja) 体重減少および肥満処置の方法

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired