AU2001264680B2 - Cannabinoid drugs - Google Patents

Cannabinoid drugs Download PDF

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Publication number
AU2001264680B2
AU2001264680B2 AU2001264680A AU2001264680A AU2001264680B2 AU 2001264680 B2 AU2001264680 B2 AU 2001264680B2 AU 2001264680 A AU2001264680 A AU 2001264680A AU 2001264680 A AU2001264680 A AU 2001264680A AU 2001264680 B2 AU2001264680 B2 AU 2001264680B2
Authority
AU
Australia
Prior art keywords
cells
thc
compound
mammal
cell proliferation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2001264680A
Other languages
English (en)
Other versions
AU2001264680A1 (en
Inventor
Sumner Burstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indevus Pharmaceuticals Inc
Original Assignee
Indevus Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indevus Pharmaceuticals Inc filed Critical Indevus Pharmaceuticals Inc
Publication of AU2001264680A1 publication Critical patent/AU2001264680A1/en
Assigned to ZURIER, ROBERT, MANHATTAN PHARMACEUTICALS, INC., RECHT, LAWRENCE reassignment ZURIER, ROBERT Amend patent request/document other than specification (104) Assignors: ATLANTIC TECHNOLOGY VENTURES, INC., RECHT, LAWRENCE, ZURIER, ROBERT
Application granted granted Critical
Publication of AU2001264680B2 publication Critical patent/AU2001264680B2/en
Assigned to ZURIER, ROBERT, INDEVUS PHARMACEUTICALS, INC., RECHT, LAWRENCE reassignment ZURIER, ROBERT Request for Assignment Assignors: Manhatten Pharmaceuticals, Inc, RECHT, LAWRENCE, ZURIER, ROBERT
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)
AU2001264680A 2000-05-17 2001-05-17 Cannabinoid drugs Ceased AU2001264680B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20493500P 2000-05-17 2000-05-17
US60/204,935 2000-05-17
PCT/US2001/016150 WO2001087297A1 (en) 2000-05-17 2001-05-17 Cannabinoid drugs

Publications (2)

Publication Number Publication Date
AU2001264680A1 AU2001264680A1 (en) 2002-02-14
AU2001264680B2 true AU2001264680B2 (en) 2006-09-14

Family

ID=22760084

Family Applications (5)

Application Number Title Priority Date Filing Date
AU2001264680A Ceased AU2001264680B2 (en) 2000-05-17 2001-05-17 Cannabinoid drugs
AU2001263217A Abandoned AU2001263217A1 (en) 2000-05-17 2001-05-17 Methods for decreasing cell proliferation based on (3r, 4r)delta8-tetrahydrocannabinol-11-oic acids
AU2001261695A Ceased AU2001261695B2 (en) 2000-05-17 2001-05-17 Methods for decreasing cell proliferation based on (3r, 4r)-delta8-tetrahydrocannabinol-11-oic acids
AU6169501A Pending AU6169501A (en) 2000-05-17 2001-05-17 Methods for decreasing cell proliferation based on (3r, 4r)-delta8-tetrahydrocannabinol-11-oic acids
AU6468001A Pending AU6468001A (en) 2000-05-17 2001-05-17 Cannabinoid drugs

Family Applications After (4)

Application Number Title Priority Date Filing Date
AU2001263217A Abandoned AU2001263217A1 (en) 2000-05-17 2001-05-17 Methods for decreasing cell proliferation based on (3r, 4r)delta8-tetrahydrocannabinol-11-oic acids
AU2001261695A Ceased AU2001261695B2 (en) 2000-05-17 2001-05-17 Methods for decreasing cell proliferation based on (3r, 4r)-delta8-tetrahydrocannabinol-11-oic acids
AU6169501A Pending AU6169501A (en) 2000-05-17 2001-05-17 Methods for decreasing cell proliferation based on (3r, 4r)-delta8-tetrahydrocannabinol-11-oic acids
AU6468001A Pending AU6468001A (en) 2000-05-17 2001-05-17 Cannabinoid drugs

Country Status (13)

Country Link
US (2) US6448288B1 (enExample)
EP (2) EP1307186A4 (enExample)
JP (2) JP2003533479A (enExample)
CN (2) CN1273123C (enExample)
AT (1) ATE406156T1 (enExample)
AU (5) AU2001264680B2 (enExample)
CA (2) CA2408961A1 (enExample)
DE (1) DE60135557D1 (enExample)
HU (2) HUP0700039A2 (enExample)
IL (3) IL152892A0 (enExample)
NZ (2) NZ523029A (enExample)
RU (2) RU2273476C2 (enExample)
WO (3) WO2001087296A1 (enExample)

Families Citing this family (33)

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WO2003075917A1 (en) 2002-03-08 2003-09-18 Signal Pharmaceuticals, Inc. Combination therapy for treating, preventing or managing proliferative disorders and cancers
WO2004103410A1 (en) 2002-06-06 2004-12-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods compositions and articles of manufacture for modulating bone growth
AU2003303376A1 (en) * 2002-12-19 2004-07-22 University Of Massachusetts Cannabinoid analogs as peroxisome proliferator activated nuclear receptor gamma activators
ATE496901T1 (de) * 2003-05-20 2011-02-15 Univ Tennessee Res Foundation Cannabinoidderivate, verfahren zu deren herstellung und deren verwendung
US20050070718A1 (en) 2003-09-30 2005-03-31 Abbott Gmbh & Co. Kg Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
US8580842B2 (en) 2003-09-30 2013-11-12 Abbott Gmbh & Co. Kg Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
GB2418612A (en) * 2004-10-01 2006-04-05 Gw Pharma Ltd Inhibition of tumour cell migration with cannabinoids
WO2006065792A2 (en) * 2004-12-13 2006-06-22 Indevus Pharmaceuticals, Inc. Treatment of interstitial cystitis using cannabinoid analogs
US20060128794A1 (en) 2004-12-13 2006-06-15 Indevus Pharmaceuticals, Inc. Treatment of interstitial cystitis using (6aR,10aR)-delta8-tetrahydrocannabinol-11-OIC acids
US20070037873A1 (en) * 2005-08-08 2007-02-15 Zurier Robert B Airway remodeling treatments
US7597910B2 (en) * 2005-08-20 2009-10-06 Slgm Medical Research Institute Compositions and methods for treating prostate disorders
CN101316832A (zh) 2005-09-29 2008-12-03 Amr科技公司 δ-9-四氢大麻酚的生成方法
US20070093519A1 (en) * 2005-10-20 2007-04-26 Indevus Pharmaceuticals, Inc. Anti-emetic uses of cannabinoid analogs
US20070099988A1 (en) * 2005-10-31 2007-05-03 Indevus Pharmaceuticals, Inc. Anti-emetic uses of (3r, 4r)-delta8-tetrahydrocannabinol-11-oic acids
US8486979B2 (en) 2006-12-12 2013-07-16 Abbvie Inc. 1,2,4 oxadiazole compounds and methods of use thereof
US20080167286A1 (en) 2006-12-12 2008-07-10 Abbott Laboratories Pharmaceutical compositions and their methods of use
UY30846A1 (es) 2006-12-30 2008-07-31 Abbott Gmbh & Amp Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos
US7781650B2 (en) * 2007-04-30 2010-08-24 Monsanto Technology Llc Plants and seeds of corn variety CV202909
WO2008144475A1 (en) 2007-05-17 2008-11-27 California Pacific Medical Center Methods and compositions for treating cancer
WO2010009775A1 (de) 2007-12-07 2010-01-28 Abbott Gmbh & Co. Kg Carbamat-substituierte oxindol-derivate und ihre verwendung zur behandlung von vasopressin-abhängigen erkrankungen
JP5701607B2 (ja) 2007-12-07 2015-04-15 アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー アミドメチル置換オキシインドール誘導体およびバソプレッシン依存性疾患の治療へのこれらの使用
US9023854B2 (en) 2007-12-07 2015-05-05 AbbVie Deutschland GmbH & Co. KG 5-halogen-substituted oxindole derivatives and use thereof for treating vasopressin-dependent diseases
JP5645217B2 (ja) 2007-12-07 2014-12-24 アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー 5,6−二置換オキシンドール誘導体およびバソプレッシン依存性疾患を治療するためのこれらの使用
GB2471987B (en) 2008-06-04 2012-02-22 Gw Pharma Ltd Anti-tumoural effects of cannabinoid combinations
EP2435080A2 (en) 2009-05-29 2012-04-04 Abbott Laboratories Pharmaceutical compositions for the treatment of pain
GB2478595B (en) 2010-03-12 2018-04-04 Gw Pharma Ltd Phytocannabinoids in the treatment of glioma
GB2487712B (en) 2011-01-04 2015-10-28 Otsuka Pharma Co Ltd Use of the phytocannabinoid cannabidiol (CBD) in combination with a standard anti-epileptic drug (SAED) in the treatment of epilepsy
GB2514054A (en) 2011-09-29 2014-11-12 Gw Pharma Ltd A pharmaceutical composition comprising the phytocannabinoids cannabidivarin (CBDV) and cannabidiol (CBD)
GB2516814B (en) 2013-06-19 2016-08-31 Otsuka Pharma Co Ltd Use of phytocannabinoids for increasing radiosensitivity in the treatment of cancer
MA49772A (fr) 2017-08-04 2021-04-21 Merck Sharp & Dohme Agonistes benzo[b]thiophène de sting pour le traitement du cancer
WO2019027857A1 (en) 2017-08-04 2019-02-07 Merck Sharp & Dohme Corp. COMBINATIONS OF PD-1 ANTAGONISTS AND STING BENZO [B] THIOPHENIC AGONISTS FOR THE TREATMENT OF CANCER
CN111233814A (zh) * 2020-03-02 2020-06-05 福建省中科生物股份有限公司 一种萜酚类化合物zkyy-057及其制备方法和应用
US12029718B2 (en) 2021-11-09 2024-07-09 Cct Sciences, Llc Process for production of essentially pure delta-9-tetrahydrocannabinol

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5A (en) * 1836-08-10 Thomas Blanchard Machine for mortising solid wooden shells of ships' tackle-blocks
US4327028A (en) * 1978-08-17 1982-04-27 Calcol, Inc. Composition of matter
ZA885929B (en) * 1987-08-25 1989-04-26 Oxi Gene Inc Agents for use in tumor or cancer cell killing therapy
US4973603A (en) * 1988-06-16 1990-11-27 Sumner Burstein Platelet activating factor antagonist and methods of use therefor
US4880030A (en) * 1988-07-25 1989-11-14 Terry Paul E Safety flow control fluid shutoff device
US5635530A (en) * 1991-09-12 1997-06-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem (3S,4S)-delta-6-tetrahydrocannabinol-7-oic acids and derivatives thereof, processors for their preparation and pharmaceutical compositions containing them
US5538993A (en) * 1991-09-12 1996-07-23 Yissum Research Development Company Certain tetrahydrocannabinol-7-oic acid derivatives
US5338753A (en) 1992-07-14 1994-08-16 Sumner H. Burstein (3R,4R)-Δ6 -tetrahydrocannabinol-7-oic acids useful as antiinflammatory agents and analgesics
US6162829A (en) * 1997-10-17 2000-12-19 Atlantic Pharmaceuticals, Inc. (3R,4R)-Δ8 -tetrahydrocannabinol-11-oic acids useful as antiinflammatory agents and analgesics
ES1045342Y (es) * 2000-02-11 2001-02-16 Alvarez Manuel Couto Expositor giratorio para postales, fotos y similares.

Also Published As

Publication number Publication date
DE60135557D1 (de) 2008-10-09
WO2001087295A8 (en) 2003-04-10
WO2001087296A1 (en) 2001-11-22
AU2001261695B2 (en) 2005-06-16
EP1307186A1 (en) 2003-05-07
WO2001087297A1 (en) 2001-11-22
RU2273476C2 (ru) 2006-04-10
IL152891A0 (en) 2003-06-24
CN1227007C (zh) 2005-11-16
ATE406156T1 (de) 2008-09-15
EP1307186A4 (en) 2005-10-19
EP1307188A1 (en) 2003-05-07
US6914072B2 (en) 2005-07-05
US6448288B1 (en) 2002-09-10
NZ523029A (en) 2004-11-26
WO2001087295A1 (en) 2001-11-22
US20040225011A1 (en) 2004-11-11
AU6468001A (en) 2001-11-26
CA2408961A1 (en) 2001-11-22
NZ523028A (en) 2004-09-24
HUP0700038A2 (en) 2007-05-02
CA2409005A1 (en) 2001-11-22
AU2001263217A1 (en) 2001-11-26
US20020022653A1 (en) 2002-02-21
CN1273123C (zh) 2006-09-06
IL152892A0 (en) 2003-06-24
HUP0700039A2 (en) 2007-05-02
AU6169501A (en) 2001-11-26
IL152892A (en) 2010-06-30
JP2003533478A (ja) 2003-11-11
EP1307188B1 (en) 2008-08-27
EP1307188A4 (en) 2005-07-06
JP2003533479A (ja) 2003-11-11
CN1452485A (zh) 2003-10-29
RU2272620C2 (ru) 2006-03-27
CN1447685A (zh) 2003-10-08

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Legal Events

Date Code Title Description
TC Change of applicant's name (sec. 104)

Owner name: RECHT, LAWRENCE; ZURIER, ROBERT; MANHATTAN PHARMAC

Free format text: FORMER NAME: ZURIER, ROBERT; ATLANTIC TECHNOLOGY VENTURES, INC.; RECHT, LAWRENCE

PC1 Assignment before grant (sect. 113)

Owner name: RECHT, LAWRENCE; ZURIER, ROBERT; INDEVUS PHARMACEU

Free format text: FORMER APPLICANT(S): MANHATTEN PHARMACEUTICALS, INC; RECHT, LAWRENCE; ZURIER, ROBERT

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired