ATE406156T1 - Ajulemische säure zur krebsbehandlung - Google Patents
Ajulemische säure zur krebsbehandlungInfo
- Publication number
- ATE406156T1 ATE406156T1 AT01939128T AT01939128T ATE406156T1 AT E406156 T1 ATE406156 T1 AT E406156T1 AT 01939128 T AT01939128 T AT 01939128T AT 01939128 T AT01939128 T AT 01939128T AT E406156 T1 ATE406156 T1 AT E406156T1
- Authority
- AT
- Austria
- Prior art keywords
- cancer treatment
- ajulemic acid
- ajulemic
- acid
- tetrahydrocannabinol
- Prior art date
Links
- YCHYFHOSGQABSW-RTBURBONSA-N (6ar,10ar)-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene-9-carboxylic acid Chemical compound C1C(C(O)=O)=CC[C@H]2C(C)(C)OC3=CC(C(C)(C)CCCCCC)=CC(O)=C3[C@@H]21 YCHYFHOSGQABSW-RTBURBONSA-N 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 229930003827 cannabinoid Natural products 0.000 abstract 1
- 239000003557 cannabinoid Substances 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- -1 compounds (derivatives of tetrahydrocannabinol Chemical class 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20493500P | 2000-05-17 | 2000-05-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE406156T1 true ATE406156T1 (de) | 2008-09-15 |
Family
ID=22760084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01939128T ATE406156T1 (de) | 2000-05-17 | 2001-05-17 | Ajulemische säure zur krebsbehandlung |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6448288B1 (enExample) |
| EP (2) | EP1307186A4 (enExample) |
| JP (2) | JP2003533479A (enExample) |
| CN (2) | CN1273123C (enExample) |
| AT (1) | ATE406156T1 (enExample) |
| AU (5) | AU2001264680B2 (enExample) |
| CA (2) | CA2408961A1 (enExample) |
| DE (1) | DE60135557D1 (enExample) |
| HU (2) | HUP0700039A2 (enExample) |
| IL (3) | IL152892A0 (enExample) |
| NZ (2) | NZ523029A (enExample) |
| RU (2) | RU2273476C2 (enExample) |
| WO (3) | WO2001087296A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003075917A1 (en) | 2002-03-08 | 2003-09-18 | Signal Pharmaceuticals, Inc. | Combination therapy for treating, preventing or managing proliferative disorders and cancers |
| WO2004103410A1 (en) | 2002-06-06 | 2004-12-02 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Methods compositions and articles of manufacture for modulating bone growth |
| AU2003303376A1 (en) * | 2002-12-19 | 2004-07-22 | University Of Massachusetts | Cannabinoid analogs as peroxisome proliferator activated nuclear receptor gamma activators |
| ATE496901T1 (de) * | 2003-05-20 | 2011-02-15 | Univ Tennessee Res Foundation | Cannabinoidderivate, verfahren zu deren herstellung und deren verwendung |
| US20050070718A1 (en) | 2003-09-30 | 2005-03-31 | Abbott Gmbh & Co. Kg | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them |
| US8580842B2 (en) | 2003-09-30 | 2013-11-12 | Abbott Gmbh & Co. Kg | Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them |
| GB2418612A (en) * | 2004-10-01 | 2006-04-05 | Gw Pharma Ltd | Inhibition of tumour cell migration with cannabinoids |
| WO2006065792A2 (en) * | 2004-12-13 | 2006-06-22 | Indevus Pharmaceuticals, Inc. | Treatment of interstitial cystitis using cannabinoid analogs |
| US20060128794A1 (en) | 2004-12-13 | 2006-06-15 | Indevus Pharmaceuticals, Inc. | Treatment of interstitial cystitis using (6aR,10aR)-delta8-tetrahydrocannabinol-11-OIC acids |
| US20070037873A1 (en) * | 2005-08-08 | 2007-02-15 | Zurier Robert B | Airway remodeling treatments |
| US7597910B2 (en) * | 2005-08-20 | 2009-10-06 | Slgm Medical Research Institute | Compositions and methods for treating prostate disorders |
| CN101316832A (zh) | 2005-09-29 | 2008-12-03 | Amr科技公司 | δ-9-四氢大麻酚的生成方法 |
| US20070093519A1 (en) * | 2005-10-20 | 2007-04-26 | Indevus Pharmaceuticals, Inc. | Anti-emetic uses of cannabinoid analogs |
| US20070099988A1 (en) * | 2005-10-31 | 2007-05-03 | Indevus Pharmaceuticals, Inc. | Anti-emetic uses of (3r, 4r)-delta8-tetrahydrocannabinol-11-oic acids |
| US8486979B2 (en) | 2006-12-12 | 2013-07-16 | Abbvie Inc. | 1,2,4 oxadiazole compounds and methods of use thereof |
| US20080167286A1 (en) | 2006-12-12 | 2008-07-10 | Abbott Laboratories | Pharmaceutical compositions and their methods of use |
| UY30846A1 (es) | 2006-12-30 | 2008-07-31 | Abbott Gmbh & Amp | Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos |
| US7781650B2 (en) * | 2007-04-30 | 2010-08-24 | Monsanto Technology Llc | Plants and seeds of corn variety CV202909 |
| WO2008144475A1 (en) | 2007-05-17 | 2008-11-27 | California Pacific Medical Center | Methods and compositions for treating cancer |
| WO2010009775A1 (de) | 2007-12-07 | 2010-01-28 | Abbott Gmbh & Co. Kg | Carbamat-substituierte oxindol-derivate und ihre verwendung zur behandlung von vasopressin-abhängigen erkrankungen |
| JP5701607B2 (ja) | 2007-12-07 | 2015-04-15 | アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー | アミドメチル置換オキシインドール誘導体およびバソプレッシン依存性疾患の治療へのこれらの使用 |
| US9023854B2 (en) | 2007-12-07 | 2015-05-05 | AbbVie Deutschland GmbH & Co. KG | 5-halogen-substituted oxindole derivatives and use thereof for treating vasopressin-dependent diseases |
| JP5645217B2 (ja) | 2007-12-07 | 2014-12-24 | アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー | 5,6−二置換オキシンドール誘導体およびバソプレッシン依存性疾患を治療するためのこれらの使用 |
| GB2471987B (en) | 2008-06-04 | 2012-02-22 | Gw Pharma Ltd | Anti-tumoural effects of cannabinoid combinations |
| EP2435080A2 (en) | 2009-05-29 | 2012-04-04 | Abbott Laboratories | Pharmaceutical compositions for the treatment of pain |
| GB2478595B (en) | 2010-03-12 | 2018-04-04 | Gw Pharma Ltd | Phytocannabinoids in the treatment of glioma |
| GB2487712B (en) | 2011-01-04 | 2015-10-28 | Otsuka Pharma Co Ltd | Use of the phytocannabinoid cannabidiol (CBD) in combination with a standard anti-epileptic drug (SAED) in the treatment of epilepsy |
| GB2514054A (en) | 2011-09-29 | 2014-11-12 | Gw Pharma Ltd | A pharmaceutical composition comprising the phytocannabinoids cannabidivarin (CBDV) and cannabidiol (CBD) |
| GB2516814B (en) | 2013-06-19 | 2016-08-31 | Otsuka Pharma Co Ltd | Use of phytocannabinoids for increasing radiosensitivity in the treatment of cancer |
| MA49772A (fr) | 2017-08-04 | 2021-04-21 | Merck Sharp & Dohme | Agonistes benzo[b]thiophène de sting pour le traitement du cancer |
| WO2019027857A1 (en) | 2017-08-04 | 2019-02-07 | Merck Sharp & Dohme Corp. | COMBINATIONS OF PD-1 ANTAGONISTS AND STING BENZO [B] THIOPHENIC AGONISTS FOR THE TREATMENT OF CANCER |
| CN111233814A (zh) * | 2020-03-02 | 2020-06-05 | 福建省中科生物股份有限公司 | 一种萜酚类化合物zkyy-057及其制备方法和应用 |
| US12029718B2 (en) | 2021-11-09 | 2024-07-09 | Cct Sciences, Llc | Process for production of essentially pure delta-9-tetrahydrocannabinol |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5A (en) * | 1836-08-10 | Thomas Blanchard | Machine for mortising solid wooden shells of ships' tackle-blocks | |
| US4327028A (en) * | 1978-08-17 | 1982-04-27 | Calcol, Inc. | Composition of matter |
| ZA885929B (en) * | 1987-08-25 | 1989-04-26 | Oxi Gene Inc | Agents for use in tumor or cancer cell killing therapy |
| US4973603A (en) * | 1988-06-16 | 1990-11-27 | Sumner Burstein | Platelet activating factor antagonist and methods of use therefor |
| US4880030A (en) * | 1988-07-25 | 1989-11-14 | Terry Paul E | Safety flow control fluid shutoff device |
| US5635530A (en) * | 1991-09-12 | 1997-06-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | (3S,4S)-delta-6-tetrahydrocannabinol-7-oic acids and derivatives thereof, processors for their preparation and pharmaceutical compositions containing them |
| US5538993A (en) * | 1991-09-12 | 1996-07-23 | Yissum Research Development Company | Certain tetrahydrocannabinol-7-oic acid derivatives |
| US5338753A (en) | 1992-07-14 | 1994-08-16 | Sumner H. Burstein | (3R,4R)-Δ6 -tetrahydrocannabinol-7-oic acids useful as antiinflammatory agents and analgesics |
| US6162829A (en) * | 1997-10-17 | 2000-12-19 | Atlantic Pharmaceuticals, Inc. | (3R,4R)-Δ8 -tetrahydrocannabinol-11-oic acids useful as antiinflammatory agents and analgesics |
| ES1045342Y (es) * | 2000-02-11 | 2001-02-16 | Alvarez Manuel Couto | Expositor giratorio para postales, fotos y similares. |
-
2001
- 2001-05-08 US US09/851,122 patent/US6448288B1/en not_active Expired - Lifetime
- 2001-05-17 HU HU0700039A patent/HUP0700039A2/hu unknown
- 2001-05-17 CA CA002408961A patent/CA2408961A1/en not_active Abandoned
- 2001-05-17 HU HU0700038A patent/HUP0700038A2/hu unknown
- 2001-05-17 RU RU2002133868/15A patent/RU2273476C2/ru not_active IP Right Cessation
- 2001-05-17 AU AU2001264680A patent/AU2001264680B2/en not_active Ceased
- 2001-05-17 CN CNB018130100A patent/CN1273123C/zh not_active Expired - Fee Related
- 2001-05-17 IL IL15289201A patent/IL152892A0/xx unknown
- 2001-05-17 RU RU2002133869/14A patent/RU2272620C2/ru not_active IP Right Cessation
- 2001-05-17 WO PCT/US2001/015927 patent/WO2001087296A1/en not_active Ceased
- 2001-05-17 EP EP01935616A patent/EP1307186A4/en not_active Withdrawn
- 2001-05-17 JP JP2001583765A patent/JP2003533479A/ja active Pending
- 2001-05-17 AU AU2001263217A patent/AU2001263217A1/en not_active Abandoned
- 2001-05-17 JP JP2001583763A patent/JP2003533478A/ja active Pending
- 2001-05-17 WO PCT/US2001/015916 patent/WO2001087295A1/en not_active Ceased
- 2001-05-17 EP EP01939128A patent/EP1307188B1/en not_active Expired - Lifetime
- 2001-05-17 IL IL15289101A patent/IL152891A0/xx unknown
- 2001-05-17 WO PCT/US2001/016150 patent/WO2001087297A1/en not_active Ceased
- 2001-05-17 AU AU2001261695A patent/AU2001261695B2/en not_active Ceased
- 2001-05-17 AT AT01939128T patent/ATE406156T1/de not_active IP Right Cessation
- 2001-05-17 US US10/276,819 patent/US6914072B2/en not_active Expired - Fee Related
- 2001-05-17 NZ NZ523029A patent/NZ523029A/en unknown
- 2001-05-17 AU AU6169501A patent/AU6169501A/xx active Pending
- 2001-05-17 CA CA002409005A patent/CA2409005A1/en not_active Abandoned
- 2001-05-17 NZ NZ523028A patent/NZ523028A/en unknown
- 2001-05-17 CN CNB018129161A patent/CN1227007C/zh not_active Expired - Fee Related
- 2001-05-17 DE DE60135557T patent/DE60135557D1/de not_active Expired - Fee Related
- 2001-05-17 AU AU6468001A patent/AU6468001A/xx active Pending
-
2002
- 2002-11-17 IL IL152892A patent/IL152892A/en not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |