AU2001258488A1 - Uridine derivatives as antibiotics - Google Patents

Uridine derivatives as antibiotics

Info

Publication number
AU2001258488A1
AU2001258488A1 AU2001258488A AU5848801A AU2001258488A1 AU 2001258488 A1 AU2001258488 A1 AU 2001258488A1 AU 2001258488 A AU2001258488 A AU 2001258488A AU 5848801 A AU5848801 A AU 5848801A AU 2001258488 A1 AU2001258488 A1 AU 2001258488A1
Authority
AU
Australia
Prior art keywords
antibiotics
uridine derivatives
uridine
derivatives
formulawhere
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001258488A
Other languages
English (en)
Inventor
Jozsef Aszodi
Stanislas Didierlaurent
Christophe Dini
Nathalie Drochon
Jean-Claude Guillot
Jidong Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of AU2001258488A1 publication Critical patent/AU2001258488A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU2001258488A 2000-05-09 2001-05-04 Uridine derivatives as antibiotics Abandoned AU2001258488A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0005858A FR2808797A1 (fr) 2000-05-09 2000-05-09 Nouveaux derives de l'uridine, leur procede de preparation et leur application comme medicaments
FR0005858 2000-05-09
PCT/FR2001/001356 WO2001085750A1 (fr) 2000-05-09 2001-05-04 Derives de l'uridine comme antibiotiques

Publications (1)

Publication Number Publication Date
AU2001258488A1 true AU2001258488A1 (en) 2001-11-20

Family

ID=8849999

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001258488A Abandoned AU2001258488A1 (en) 2000-05-09 2001-05-04 Uridine derivatives as antibiotics

Country Status (12)

Country Link
US (1) US6875752B2 (de)
EP (1) EP1284984B1 (de)
JP (1) JP4994557B2 (de)
CN (1) CN1191264C (de)
AT (1) ATE344272T1 (de)
AU (1) AU2001258488A1 (de)
CA (1) CA2408453A1 (de)
DE (1) DE60124245T2 (de)
FR (1) FR2808797A1 (de)
IL (1) IL152614A0 (de)
MX (1) MXPA02010961A (de)
WO (1) WO2001085750A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070112774A (ko) * 2005-03-04 2007-11-27 다브르 파마 리미티드 베타―아노머가 많은２１데옥시，２１，２１－디플루오로－ｄ－리보푸라노실뉴클레오시드의 제조를 위한 중간체 및 제조 방법
EA201190178A1 (ru) * 2009-03-20 2012-06-29 Алиос Биофарма, Инк. Замещённые нуклеозидные и нуклеотидные аналоги
CN103209987B (zh) 2010-09-22 2017-06-06 艾丽奥斯生物制药有限公司 取代的核苷酸类似物
AU2012358804B2 (en) 2011-12-22 2018-04-19 Alios Biopharma, Inc. Substituted phosphorothioate nucleotide analogs
WO2013142124A1 (en) 2012-03-21 2013-09-26 Vertex Pharmaceuticals Incorporated Solid forms of a thiophosphoramidate nucleotide prodrug
US9012427B2 (en) 2012-03-22 2015-04-21 Alios Biopharma, Inc. Pharmaceutical combinations comprising a thionucleotide analog
BR112020000196A2 (pt) 2017-07-07 2020-07-07 Epicentrx, Inc. composições para administração parenteral de agentes terapêuticos
WO2019140158A1 (en) * 2018-01-12 2019-07-18 California Institute Of Technology Glycosyltransferase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02306992A (ja) * 1989-05-20 1990-12-20 Rikagaku Kenkyusho 抗生物質ｒｋ―１０６１ｇ及びｒｋ―１０６１ｈ並びにその製造法
GB9004407D0 (en) * 1990-02-27 1990-04-25 Fujisawa Pharmaceutical Co New uronic acid derivatives,a process for their production and a pharmaceutical composition containing the same
DE69735099T2 (de) * 1996-04-26 2006-11-02 Daiichi Pharmaceutical Co., Ltd. Antibiotika rk-1061 und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
CA2408453A1 (fr) 2001-11-15
ATE344272T1 (de) 2006-11-15
FR2808797A1 (fr) 2001-11-16
JP4994557B2 (ja) 2012-08-08
IL152614A0 (en) 2003-06-24
CN1191264C (zh) 2005-03-02
US6875752B2 (en) 2005-04-05
JP2003532736A (ja) 2003-11-05
DE60124245D1 (de) 2006-12-14
EP1284984A1 (de) 2003-02-26
DE60124245T2 (de) 2007-05-31
EP1284984B1 (de) 2006-11-02
MXPA02010961A (es) 2003-03-27
WO2001085750A1 (fr) 2001-11-15
US20030130227A1 (en) 2003-07-10
CN1427846A (zh) 2003-07-02

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application