AU2001294606A1 - Substituted azepino(4,5b)indoline derivatives - Google Patents

Substituted azepino(4,5b)indoline derivatives

Info

Publication number
AU2001294606A1
AU2001294606A1 AU2001294606A AU9460601A AU2001294606A1 AU 2001294606 A1 AU2001294606 A1 AU 2001294606A1 AU 2001294606 A AU2001294606 A AU 2001294606A AU 9460601 A AU9460601 A AU 9460601A AU 2001294606 A1 AU2001294606 A1 AU 2001294606A1
Authority
AU
Australia
Prior art keywords
indoline derivatives
azepino
substituted
substituted azepino
indoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001294606A
Inventor
Brad A. Acker
Michael D. Ennis
Jed F. Fisher
Kristine E. Frank
Jian-Min Fu
Eric Jon Jacobsen
William W Mc Whorter
Jeanette K. Morris
Donald Joseph Rogier Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Publication of AU2001294606A1 publication Critical patent/AU2001294606A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AU2001294606A 2000-09-20 2001-09-20 Substituted azepino(4,5b)indoline derivatives Abandoned AU2001294606A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US23437600P 2000-09-20 2000-09-20
US60234376 2000-09-20
US26604701P 2001-02-01 2001-02-01
US60266047 2001-02-01
US30196401P 2001-06-29 2001-06-29
US60301964 2001-06-29
PCT/US2001/029447 WO2002024700A2 (en) 2000-09-20 2001-09-20 SUBSTITUTED AZEPINO[4,5b]INDOLINE DERIVATIVES

Publications (1)

Publication Number Publication Date
AU2001294606A1 true AU2001294606A1 (en) 2002-04-02

Family

ID=27398561

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001294606A Abandoned AU2001294606A1 (en) 2000-09-20 2001-09-20 Substituted azepino(4,5b)indoline derivatives
AU2001292898A Abandoned AU2001292898A1 (en) 2000-09-20 2001-09-20 Substituted azepino[4,5b)indole derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2001292898A Abandoned AU2001292898A1 (en) 2000-09-20 2001-09-20 Substituted azepino[4,5b)indole derivatives

Country Status (7)

Country Link
US (4) US6586421B2 (en)
EP (2) EP1319004A2 (en)
JP (2) JP2004509894A (en)
AR (2) AR034264A1 (en)
AU (2) AU2001294606A1 (en)
PE (2) PE20020510A1 (en)
WO (2) WO2002024700A2 (en)

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JP5528699B2 (en) 2006-05-16 2014-06-25 武田薬品工業株式会社 Fused heterocyclic compounds and uses thereof
US20100209960A1 (en) * 2007-09-10 2010-08-19 Merck Sharp & Dohme Corp. Method for measuring mitochondrial membrane potential in vertebrate cells
US7816435B2 (en) * 2007-10-31 2010-10-19 Momentive Performance Materials Inc. Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom
EP2789338A3 (en) 2007-11-15 2015-01-14 Takeda Pharmaceutical Company Limited Condensed pyridine derivate and use thereof
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JP2012504137A (en) 2008-09-29 2012-02-16 アボット・ラボラトリーズ Indole derivatives and indoline derivatives and methods for their use
US9625475B2 (en) 2008-09-29 2017-04-18 Abbvie Inc. Indole and indoline derivatives and methods of use thereof
WO2010051503A1 (en) * 2008-10-31 2010-05-06 Medivation Technologies, Inc. Azepino [4, 5-b] indoles and methods of use
AR073923A1 (en) 2008-10-31 2010-12-09 Medivation Technologies Inc REQUEST (4,3-B) INDOLES CONTAINING RIGID REMAINS
US8629158B2 (en) 2009-07-01 2014-01-14 Albany Molecular Research, Inc. Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
EP2448585B1 (en) * 2009-07-01 2014-01-01 Albany Molecular Research, Inc. Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof
US8618299B2 (en) 2009-07-01 2013-12-31 Albany Molecular Research, Inc. Azinone-substituted azapolycycle MCH-1 antagonists, methods of making, and use thereof
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WO2011071136A1 (en) 2009-12-11 2011-06-16 アステラス製薬株式会社 Therapeutic agent for fibromyalgia
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WO2011103433A1 (en) * 2010-02-18 2011-08-25 Medivation Technologies, Inc. Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use
WO2011103487A1 (en) * 2010-02-18 2011-08-25 Medivation Technologies, Inc. Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use
US9040519B2 (en) 2010-02-18 2015-05-26 Medivation Technologies, Inc. Fused tetracyclic pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use
WO2011103430A1 (en) * 2010-02-19 2011-08-25 Medivation Technologies, Inc. Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use
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US9434747B2 (en) 2011-02-18 2016-09-06 Medivation Technologies, Inc. Methods of treating diabetes
US9199985B2 (en) 2011-02-18 2015-12-01 Medivation Technologies, Inc. Compounds and methods for treatment of hypertension
US20130178618A1 (en) * 2012-01-10 2013-07-11 William Allen Boulanger Novel pharmaceutical intermediates and methods for preparing the same
WO2014031167A1 (en) * 2012-08-22 2014-02-27 Medivation Technologies, Inc. Compounds and methods for treatment of hypertension
EP3525763A4 (en) 2016-10-12 2020-06-17 Intra-Cellular Therapies, Inc. Amorphous solid dispersions
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JPWO2019131902A1 (en) 2017-12-27 2020-12-10 武田薬品工業株式会社 Remedies for stress urinary incontinence and fecal incontinence
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SG11202109020QA (en) 2019-02-27 2021-09-29 Univ California N-substituted indoles and other heterocycles for treating brain disorders
WO2020176599A1 (en) 2019-02-27 2020-09-03 The Regents Of The University Of California Azepino-indoles and other heterocycles for treating brain disorders
CN111053789A (en) * 2019-11-26 2020-04-24 湖南营养树生物科技有限公司 Methods and compositions for modulating the immune system
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Also Published As

Publication number Publication date
AR035493A1 (en) 2004-06-02
AU2001292898A1 (en) 2002-04-02
JP2004509893A (en) 2004-04-02
WO2002024700A3 (en) 2002-06-13
AR034264A1 (en) 2004-02-18
WO2002024701A2 (en) 2002-03-28
US6828314B2 (en) 2004-12-07
WO2002024701A3 (en) 2002-06-13
US6583135B2 (en) 2003-06-24
US6586421B2 (en) 2003-07-01
EP1319005A2 (en) 2003-06-18
US20020107278A1 (en) 2002-08-08
US6903090B2 (en) 2005-06-07
WO2002024700A2 (en) 2002-03-28
US20030220321A1 (en) 2003-11-27
US20020077318A1 (en) 2002-06-20
EP1319004A2 (en) 2003-06-18
PE20020510A1 (en) 2002-06-12
PE20020443A1 (en) 2002-05-16
US20030225058A1 (en) 2003-12-04
JP2004509894A (en) 2004-04-02

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