AU2001254788A1 - Diagnosis of diseases associated with gene regulation - Google Patents
Diagnosis of diseases associated with gene regulationInfo
- Publication number
- AU2001254788A1 AU2001254788A1 AU2001254788A AU5478801A AU2001254788A1 AU 2001254788 A1 AU2001254788 A1 AU 2001254788A1 AU 2001254788 A AU2001254788 A AU 2001254788A AU 5478801 A AU5478801 A AU 5478801A AU 2001254788 A1 AU2001254788 A1 AU 2001254788A1
- Authority
- AU
- Australia
- Prior art keywords
- dna
- recited
- sequences
- genes
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10019058A DE10019058A1 (de) | 2000-04-06 | 2000-04-06 | Detektion von Variationen des DNA-Methylierungsprofils |
DE10019058.8 | 2000-04-06 | ||
DE10019173 | 2000-04-07 | ||
DE10019173.6 | 2000-04-07 | ||
DE10032529A DE10032529A1 (de) | 2000-06-30 | 2000-06-30 | Diagnose von bedeutenden genetischen Parametern innerhalb des Major Histocompatibility Complex (MHC) |
DE10032529.7 | 2000-06-30 | ||
DE10043826 | 2000-09-01 | ||
DE10043826.1 | 2000-09-01 | ||
PCT/EP2001/003968 WO2001077375A2 (fr) | 2000-04-06 | 2001-04-06 | Diagnostic de maladies associees a la regulation genetique |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001254788A1 true AU2001254788A1 (en) | 2001-10-23 |
Family
ID=27437807
Family Applications (9)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001275663A Abandoned AU2001275663A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with DNA replication by assessing DNA methylation |
AU7633001A Pending AU7633001A (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with apoptosis |
AU2001276330A Ceased AU2001276330B2 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with apoptosis |
AU2001289600A Abandoned AU2001289600A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated dna transcription by means of assessing the methylation status of genes associated with dna transcription |
AU2001254794A Abandoned AU2001254794A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with dna adducts |
AU2001278420A Abandoned AU2001278420A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with dna repair |
AU2001254788A Abandoned AU2001254788A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with gene regulation |
AU2001276331A Abandoned AU2001276331A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with metastasis |
AU2001277487A Abandoned AU2001277487A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with metabolism |
Family Applications Before (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001275663A Abandoned AU2001275663A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with DNA replication by assessing DNA methylation |
AU7633001A Pending AU7633001A (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with apoptosis |
AU2001276330A Ceased AU2001276330B2 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with apoptosis |
AU2001289600A Abandoned AU2001289600A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated dna transcription by means of assessing the methylation status of genes associated with dna transcription |
AU2001254794A Abandoned AU2001254794A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with dna adducts |
AU2001278420A Abandoned AU2001278420A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with dna repair |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001276331A Abandoned AU2001276331A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with metastasis |
AU2001277487A Abandoned AU2001277487A1 (en) | 2000-04-06 | 2001-04-06 | Diagnosis of diseases associated with metabolism |
Country Status (7)
Country | Link |
---|---|
US (7) | US20030148326A1 (fr) |
EP (9) | EP1278893A2 (fr) |
JP (3) | JP2003534780A (fr) |
AT (1) | ATE353975T1 (fr) |
AU (9) | AU2001275663A1 (fr) |
DE (1) | DE60126593T2 (fr) |
WO (8) | WO2001076451A2 (fr) |
Families Citing this family (79)
Publication number | Priority date | Publication date | Assignee | Title |
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US6780982B2 (en) * | 1996-07-12 | 2004-08-24 | Third Wave Technologies, Inc. | Charge tags and the separation of nucleic acid molecules |
US6818404B2 (en) | 1997-10-23 | 2004-11-16 | Exact Sciences Corporation | Methods for detecting hypermethylated nucleic acid in heterogeneous biological samples |
US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
US7955794B2 (en) | 2000-09-21 | 2011-06-07 | Illumina, Inc. | Multiplex nucleic acid reactions |
US8076063B2 (en) | 2000-02-07 | 2011-12-13 | Illumina, Inc. | Multiplexed methylation detection methods |
EP1278893A2 (fr) | 2000-04-06 | 2003-01-29 | Epigenomics AG | Diagnostic de maladies associees a la replication de l'adn |
WO2001093902A2 (fr) * | 2000-06-07 | 2001-12-13 | Biosynexus Incorporated | Molecules hybrides arn/adn immunostimulatrices |
US20040023230A1 (en) * | 2000-06-30 | 2004-02-05 | Alexander Olek | Method and nucleic acids for pharmacogenomic methylation analysis |
AUPR142500A0 (en) * | 2000-11-13 | 2000-12-07 | Human Genetic Signatures Pty Ltd | A peptide nucleic acid-based assay for the detection of specific nucleic acid sequences |
DE10128508A1 (de) | 2001-06-14 | 2003-02-06 | Epigenomics Ag | Verfahren und Nukleinsäuren für die Differenzierung von Prostata-Tumoren |
US7432050B2 (en) | 2001-10-05 | 2008-10-07 | Case Western Reserve University | Methods and compositions for detecting colon cancers |
JP2003144172A (ja) * | 2001-11-16 | 2003-05-20 | Nisshinbo Ind Inc | メチル化検出用オリゴヌクレオチド固定化基板 |
US20110151438A9 (en) * | 2001-11-19 | 2011-06-23 | Affymetrix, Inc. | Methods of Analysis of Methylation |
DE10161625A1 (de) * | 2001-12-14 | 2003-07-10 | Epigenomics Ag | Verfahren und Nukleinsäuren für die Analyse einer Lungenzell-Zellteilungsstörung |
WO2003076593A2 (fr) | 2002-03-07 | 2003-09-18 | The Johns Hopkins University School Of Medicine | Depistage genomique pour genes lies au cancer rendus epigenetiquement silencieux |
EP1344832A1 (fr) * | 2002-03-15 | 2003-09-17 | Epigenomics AG | Procédé et acides nucléiques pour l'analyse de méthylation dans le gène de melastatin |
AU2003225983A1 (en) * | 2002-03-25 | 2003-10-13 | St. Jude Children's Research Hospital | Cpg retrieval of dna from formalin-fixed pathology specimen for promoter methylation analysis |
EP1551221A4 (fr) * | 2002-07-03 | 2007-08-01 | Coley Pharm Group Inc | Compositions d'acide nucleique destinees a stimuler les reponses immunitaires |
US20040053880A1 (en) | 2002-07-03 | 2004-03-18 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
US7807803B2 (en) | 2002-07-03 | 2010-10-05 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
EP1554407B1 (fr) * | 2002-10-01 | 2009-07-29 | Epigenomics AG | Procede en vue du traitement de troubles de la proliferation de celllules mammaires |
US20060094016A1 (en) * | 2002-12-02 | 2006-05-04 | Niall Gormley | Determination of methylation of nucleic acid sequences |
DE10304219B3 (de) * | 2003-01-30 | 2004-08-19 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungsmustern mit hoher Sensitivität |
WO2004070062A2 (fr) * | 2003-02-04 | 2004-08-19 | Wyeth | Compositions et techniques de diagnostic et de traitement de cancers |
US20050009059A1 (en) * | 2003-05-07 | 2005-01-13 | Affymetrix, Inc. | Analysis of methylation status using oligonucleotide arrays |
US7799525B2 (en) | 2003-06-17 | 2010-09-21 | Human Genetic Signatures Pty Ltd. | Methods for genome amplification |
US8415100B2 (en) | 2003-08-14 | 2013-04-09 | Case Western Reserve University | Methods and compositions for detecting gastrointestinal and other cancers |
EP1660683B1 (fr) * | 2003-08-14 | 2017-04-19 | Case Western Reserve University | Procedes et compositions pour le depistage de cancers du colon |
DE10338308B4 (de) | 2003-08-15 | 2006-10-19 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungen in DNA |
ATE419394T1 (de) | 2003-09-04 | 2009-01-15 | Human Genetic Signatures Pty | Nukleinsäurenachweistest |
EP1689885B1 (fr) * | 2003-10-20 | 2012-10-17 | St Vincent's Hospital Sydney Limited | Evaluation de la prédisposition de cancer par la détermination quantitative de la méthylation dans des cellules normales d'hommes sains |
EP3269826B1 (fr) * | 2003-12-01 | 2020-03-11 | Epigenomics AG | Procédés et acides nucléiques pour l'analyse d'expression de gènes associés au développement des troubles de prolifération cellulaire de la prostate |
EP1561821B1 (fr) | 2003-12-11 | 2011-02-16 | Epigenomics AG | Marqueurs pour le pronostic de la réponse à la thérapie et/ou de la survie chez les patients du cancer du sein |
EP1568786A3 (fr) * | 2004-02-13 | 2007-08-29 | Affymetrix, Inc. (A US Entity) | Analyse de la méthylation utilisant des matrices d'acides nucléiques |
US8168777B2 (en) | 2004-04-29 | 2012-05-01 | Human Genetic Signatures Pty. Ltd. | Bisulphite reagent treatment of nucleic acid |
CN101056883B (zh) | 2004-09-10 | 2012-10-10 | 人类遗传标记控股有限公司 | 包括含有嵌入性假核苷酸(ipn)的嵌入性核酸(ina)的扩增阻断剂 |
KR20060026595A (ko) | 2004-09-21 | 2006-03-24 | (주)지노믹트리 | 제한효소와 dna 칩을 이용한 프로모터의 메틸화 검출방법 |
KR100617649B1 (ko) * | 2004-09-24 | 2006-09-04 | (주)지노믹트리 | 대장암 특이적 발현감소 유전자의 메틸화된 프로모터를 함유하는 암 진단용 조성물 및 그 용도 |
CA2589668C (fr) | 2004-12-03 | 2014-09-02 | Human Genetic Signatures Pty Ltd | Procedes de simplification d'acides nucleiques microbiens par modification chimique de cytosines |
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WO2008096146A1 (fr) | 2007-02-07 | 2008-08-14 | Solexa Limited | Préparation de matrices pour l'analyse de méthylation |
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CN111217900A (zh) * | 2018-11-27 | 2020-06-02 | 上海交通大学 | 一种血管新生的转录调控因子及其用途 |
SG11202107670TA (en) | 2019-01-18 | 2021-08-30 | Univ California | Dna methylation measurement for mammals based on conserved loci |
JP2022552400A (ja) | 2019-10-14 | 2022-12-15 | ジェンキュリクス インク | 特定の遺伝子のcpgメチル化変化を利用した肝癌診断用組成物およびその使用 |
KR102637032B1 (ko) | 2020-01-28 | 2024-02-15 | 주식회사 젠큐릭스 | 특정 유전자의 CpG 메틸화 변화를 이용한 방광암 진단용 조성물 및 이의 용도 |
WO2021206467A1 (fr) | 2020-04-08 | 2021-10-14 | 주식회사 젠큐릭스 | Composition pour diagnostiquer un cancer colorectal, un cancer rectal ou un adénome colorectal à l'aide d'un changement de méthylation cpg du gène glrb, et son utilisation |
CN111500702B (zh) * | 2020-04-26 | 2021-04-20 | 江苏大学附属医院 | RPN1基因cg00843506位点甲基化在诊断哮喘中的用途 |
WO2023175019A1 (fr) | 2022-03-15 | 2023-09-21 | Genknowme S.A. | Procédé pour déterminer la différence entre l'âge biologique et l'âge chronologique d'un sujet |
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2001
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