AU2001240578A1 - Pharmaceutically active aromatic guanylhydrazones - Google Patents

Pharmaceutically active aromatic guanylhydrazones

Info

Publication number
AU2001240578A1
AU2001240578A1 AU2001240578A AU4057801A AU2001240578A1 AU 2001240578 A1 AU2001240578 A1 AU 2001240578A1 AU 2001240578 A AU2001240578 A AU 2001240578A AU 4057801 A AU4057801 A AU 4057801A AU 2001240578 A1 AU2001240578 A1 AU 2001240578A1
Authority
AU
Australia
Prior art keywords
infections
aromatic
diseases
pharmaceutically active
prophylaxis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001240578A
Other languages
English (en)
Inventor
Gerald Bacher
Dorian Bevec
Axel Choidas
Joachim Hauber
Gyorgy Keri
Sabine Obert
Laszlo Ow"Rfi
Istvan Szekely
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Axxima Pharmaceuticals AG
Original Assignee
Axxima Pharmaceuticals AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axxima Pharmaceuticals AG filed Critical Axxima Pharmaceuticals AG
Publication of AU2001240578A1 publication Critical patent/AU2001240578A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2001240578A 2000-02-02 2001-02-02 Pharmaceutically active aromatic guanylhydrazones Abandoned AU2001240578A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17979500P 2000-02-02 2000-02-02
US60179795 2000-02-02
EP00102050 2000-02-02
EP00102050 2000-02-02
PCT/EP2001/001126 WO2001056553A2 (fr) 2000-02-02 2001-02-02 Guanylhydrazones aromatiques, actives sur le plan pharmacologique

Publications (1)

Publication Number Publication Date
AU2001240578A1 true AU2001240578A1 (en) 2001-08-14

Family

ID=26070491

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001240578A Abandoned AU2001240578A1 (en) 2000-02-02 2001-02-02 Pharmaceutically active aromatic guanylhydrazones

Country Status (7)

Country Link
US (2) US20030203969A1 (fr)
EP (1) EP1255541B1 (fr)
AT (1) ATE308982T1 (fr)
AU (1) AU2001240578A1 (fr)
DE (1) DE60114772T2 (fr)
ES (1) ES2250363T3 (fr)
WO (1) WO2001056553A2 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001269092A1 (en) * 2000-06-27 2002-01-08 Axxima Pharmaceuticals Ag Inhibitors of hepatitis b virus infection
WO2003006426A1 (fr) * 2001-07-13 2003-01-23 Axxima Pharmaceuticals Ag Guanylhydrazones aromatiques utilises comme composes efficaces contre les maladies nerveuses
US7001924B2 (en) 2001-09-21 2006-02-21 Message Pharmaceuticals Inhibitors of RNase P proteins as antibacterial compounds
JP2005511608A (ja) 2001-11-07 2005-04-28 エフ．ホフマン−ラ　ロシュ　アーゲー アミノピリミジン類及び−ピリジン類
EP1389480A1 (fr) * 2002-08-14 2004-02-18 Mondobiotech Interferon SA Utilisation thérapeutique de guanylhydrazones pour l'inhibition des procédés dépendant du CD83 et de la maturation des cellules dendritiques
EP1413300A1 (fr) * 2002-10-26 2004-04-28 Mondobiotech SA Pyrimidinium-Guanidiniminoethylphenyl-guanidinoalkyl-amines et guanidiniminoethylphenyl-guanidinoalkylamines comme substances thérapeutiques actives
DK1583542T3 (da) * 2003-01-14 2008-09-22 Gilead Sciences Inc Sammensætninger og fremgangsmåder til antiviral kombinationsterapi
US20070269420A1 (en) * 2003-11-24 2007-11-22 Chunduru Srinivas K Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases
US7244765B2 (en) 2004-06-25 2007-07-17 Cytokine Pharmasciences, Inc Guanylhydrazone salts, compositions, processes of making and methods of using
BRPI0514452A8 (pt) * 2004-08-17 2018-02-06 Cytokine Pharmasciences Inc Composições, métodos de fabricação e uso de compostos de guanilhidrazona
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
TWI375560B (en) * 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
DE102006028371A1 (de) * 2006-06-19 2007-12-20 Rheinische Friedrich-Wilhelms Universität Mittel gegen Malaria
US20100104536A1 (en) * 2007-03-20 2010-04-29 Indravadan Ambalal Modi P38 inhibitors
CA2690410C (fr) 2007-06-12 2015-09-29 Provid Pharmaceuticals, Inc. Inhibiteurs de kinases, leurs compositions et procedes d'utilisation
RU2477271C2 (ru) * 2011-01-12 2013-03-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Кабардино-Балкарский государственный университет им. Х.М. Бербекова" (КБГУ) Моно- и дикетимины на основе 4,4'-диацетилдифенилоксида и гуанидина и способ их получения
JP6218229B2 (ja) 2011-12-28 2017-10-25 京都府公立大学法人 角膜内皮細胞の培養正常化
US10813920B2 (en) 2013-11-14 2020-10-27 The Doshisha Drug for treating corneal endothelium by promoting cell proliferation or inhibiting cell damage
CN110331110B (zh) * 2019-07-26 2021-07-13 中南民族大学 一种利用废糖蜜和细菌高效还原水中六价铬并回收铬的方法
WO2023230431A1 (fr) * 2022-05-23 2023-11-30 Glaxo Wellcome Uk Limited Inhibiteurs de désoxyhypusine synthase pour le traitement et la prévention d'infections par le virus respiratoire

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US573684A (en) * 1896-12-22 Alexander hill motes
US5599984A (en) * 1994-01-21 1997-02-04 The Picower Institute For Medical Research Guanylhydrazones and their use to treat inflammatory conditions
US6008255A (en) * 1994-01-21 1999-12-28 The Picower Institute For Medical Research Guanylhydrazones and their use to treat inflammatory conditions
DE69739734D1 (de) * 1996-11-15 2010-02-25 Cytokine Pharmasciences Inc Guanylhydrazone die nützlich sind zur behandlung von mit t-zellen verbundenen krankheiten

Also Published As

Publication number Publication date
EP1255541B1 (fr) 2005-11-09
WO2001056553A3 (fr) 2002-03-28
DE60114772T2 (de) 2006-07-20
EP1255541A2 (fr) 2002-11-13
DE60114772D1 (de) 2005-12-15
ATE308982T1 (de) 2005-11-15
US20050171176A1 (en) 2005-08-04
US20030203969A1 (en) 2003-10-30
ES2250363T3 (es) 2006-04-16
WO2001056553A2 (fr) 2001-08-09

Similar Documents

Publication Publication Date Title
AU2001240578A1 (en) Pharmaceutically active aromatic guanylhydrazones
BRPI0307267B8 (pt) uso de compostos inibidores de beta-lactamases e composições farmacêuticas para terapia antibacteriana
BR0213522A (pt) Composto, composição farmacêutica, métodos de inibir a hiv integrase e para prevenir ou tratar a infecção pelo hiv ou para prevenir, tratar ou retardar o inìcio da aids em um paciente, e, combinação útil para tratar ou prevenir a infecção pelo hiv ou para prevenir, tratar ou retardar o inìcio da aids
UA94901C2 (ru) Антибактериальные производные пиперидина
GEP20053429B (en) 3-Aminoquinazolin-2,4-Dione, Pharmaceutical Composition Containing Them and Use Thereof as Antibacterial Agents
BG103945A (en) Derivatives of 4&#34;-substituted-9-deoxo-9a-aza-9a-homoerythromycin a
TW200738702A (en) HIV reverse transcriptase inhibitors
TW200722081A (en) New therapeutic combinations for the treatment or prevention of depression
BG108498A (en) New derivatives of oxazolidinones as antibacterial agents
BR0012253A (pt) Derivado de 1-metilcarbapenem, composição farmacêutica para a prevenção ou tratamento de infecções bacterianas, uso de uma forma cristalina de derivado de 1-metilcarbapenem, e, método para a prevenção ou tratamento de infecções bacterianas
HUP0004282A2 (hu) 2-Halogén-6-0-szubsztituált ketolidszármazékok
GEP20084437B (en) Novel lincomycin derivatives possessing antimicrobial activity
WO2007149366B1 (fr) Amélioration prolongée d&#39;une fonction rénale comprenant une administration peu fréquente d&#39;un aa1ra
WO2003089446A3 (fr) Derives de 5-o-mycaminosyltylonide substitues en 23-o
BRPI0409881A (pt) compostos, composições farmacêuticas, método para o tratamento ou profilaxia de doenças, e, usos de compostos e de um ou mais compostos em combinação com outros compostos farmacologicamente ativos
NO20074167L (no) Peptidiske forbindelser
CA2380455A1 (fr) 9a-azalides a activite antibacterienne
SE0000303D0 (sv) Novel compounds
PT1411956E (pt) Utilizacao de polissacaridos sobre-sulfatados como inibidores de vih
MXPA04005033A (es) Composicion farmaceutica que comprende una combinacion de metformina y acido 4-oxobutanoico y el uso de la misma para el tratamiento contra diabetes.
WO2005072204A3 (fr) Derives d&#39;azalide 8a 6,11-3c-bicyclique
CA2247232A1 (fr) Composition microbienne
WO2009077485A3 (fr) 1(2)h-tétrazol-5-yl-phényl-oxazolidinones comme agents antibactériens
MXPA05007724A (es) Agentes antibacterianos.
YU30602A (sh) Primena 2-amino-3,4-dihidro-hinazolina za proizvodnju leka za lečenje ili profilaksu bolesti koje su prouzrokovane ishemičnim stanjima