ATE308982T1 - Aromatisches guanylhydrazon zur behandlung resistenter viraler infektionen - Google Patents

Aromatisches guanylhydrazon zur behandlung resistenter viraler infektionen

Info

Publication number
ATE308982T1
ATE308982T1 AT01911580T AT01911580T ATE308982T1 AT E308982 T1 ATE308982 T1 AT E308982T1 AT 01911580 T AT01911580 T AT 01911580T AT 01911580 T AT01911580 T AT 01911580T AT E308982 T1 ATE308982 T1 AT E308982T1
Authority
AT
Austria
Prior art keywords
aromatic
treatment
infections
diseases
prophylaxis
Prior art date
Application number
AT01911580T
Other languages
English (en)
Inventor
Dorian Bevec
Joachim Hauber
Sabine Obert
Gyorgy Keri
Laszlo Orfi
Istvan Szekely
Axel Choidas
Gerald Bacher
Original Assignee
Dorian Bevec
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dorian Bevec filed Critical Dorian Bevec
Application granted granted Critical
Publication of ATE308982T1 publication Critical patent/ATE308982T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01911580T 2000-02-02 2001-02-02 Aromatisches guanylhydrazon zur behandlung resistenter viraler infektionen ATE308982T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17979500P 2000-02-02 2000-02-02
EP00102050 2000-02-02
PCT/EP2001/001126 WO2001056553A2 (en) 2000-02-02 2001-02-02 Pharmaceutically active aromatic guanylhydrazones

Publications (1)

Publication Number Publication Date
ATE308982T1 true ATE308982T1 (de) 2005-11-15

Family

ID=26070491

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01911580T ATE308982T1 (de) 2000-02-02 2001-02-02 Aromatisches guanylhydrazon zur behandlung resistenter viraler infektionen

Country Status (7)

Country Link
US (2) US20030203969A1 (de)
EP (1) EP1255541B1 (de)
AT (1) ATE308982T1 (de)
AU (1) AU2001240578A1 (de)
DE (1) DE60114772T2 (de)
ES (1) ES2250363T3 (de)
WO (1) WO2001056553A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001269092A1 (en) * 2000-06-27 2002-01-08 Axxima Pharmaceuticals Ag Inhibitors of hepatitis b virus infection
WO2003006426A1 (en) * 2001-07-13 2003-01-23 Axxima Pharmaceuticals Ag Aromatic guanylhydrazones as effective compounds against neurodiseases
US7001924B2 (en) 2001-09-21 2006-02-21 Message Pharmaceuticals Inhibitors of RNase P proteins as antibacterial compounds
JP2005511608A (ja) 2001-11-07 2005-04-28 エフ．ホフマン−ラ　ロシュ　アーゲー アミノピリミジン類及び−ピリジン類
EP1389480A1 (de) * 2002-08-14 2004-02-18 Mondobiotech Interferon SA Therapeutische Anwendung von Guanylhydrazone zur Hemmung von CD83 abhängige Verfahren und Reifung der dendritischen Zellen
EP1413300A1 (de) * 2002-10-26 2004-04-28 Mondobiotech SA Pyrimidinium-Guanidiniminoethylphenyl-Guanidinoalkyl-Amine und Guanidiniminoethylphenyl-Guanidinoalkylamine als pharmazeutische Wirkstoffe
DK1583542T3 (da) * 2003-01-14 2008-09-22 Gilead Sciences Inc Sammensætninger og fremgangsmåder til antiviral kombinationsterapi
US20070269420A1 (en) * 2003-11-24 2007-11-22 Chunduru Srinivas K Compounds, Compositions and Methods for Treatment and Prophylaxis of Hepatitis C Viral Infections and Associated Diseases
US7244765B2 (en) 2004-06-25 2007-07-17 Cytokine Pharmasciences, Inc Guanylhydrazone salts, compositions, processes of making and methods of using
BRPI0514452A8 (pt) * 2004-08-17 2018-02-06 Cytokine Pharmasciences Inc Composições, métodos de fabricação e uso de compostos de guanilhidrazona
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
TWI375560B (en) * 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
DE102006028371A1 (de) * 2006-06-19 2007-12-20 Rheinische Friedrich-Wilhelms Universität Mittel gegen Malaria
US20100104536A1 (en) * 2007-03-20 2010-04-29 Indravadan Ambalal Modi P38 inhibitors
CA2690410C (en) 2007-06-12 2015-09-29 Provid Pharmaceuticals, Inc. Kinase inhibitors, compositions thereof, and methods of use therewith
RU2477271C2 (ru) * 2011-01-12 2013-03-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Кабардино-Балкарский государственный университет им. Х.М. Бербекова" (КБГУ) Моно- и дикетимины на основе 4,4'-диацетилдифенилоксида и гуанидина и способ их получения
JP6218229B2 (ja) 2011-12-28 2017-10-25 京都府公立大学法人 角膜内皮細胞の培養正常化
US10813920B2 (en) 2013-11-14 2020-10-27 The Doshisha Drug for treating corneal endothelium by promoting cell proliferation or inhibiting cell damage
CN110331110B (zh) * 2019-07-26 2021-07-13 中南民族大学 一种利用废糖蜜和细菌高效还原水中六价铬并回收铬的方法
WO2023230431A1 (en) * 2022-05-23 2023-11-30 Glaxo Wellcome Uk Limited Inhibitors of deoxyhypusine synthase for the treatment and prevention of respiratory virus infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US573684A (en) * 1896-12-22 Alexander hill motes
US5599984A (en) * 1994-01-21 1997-02-04 The Picower Institute For Medical Research Guanylhydrazones and their use to treat inflammatory conditions
US6008255A (en) * 1994-01-21 1999-12-28 The Picower Institute For Medical Research Guanylhydrazones and their use to treat inflammatory conditions
DE69739734D1 (de) * 1996-11-15 2010-02-25 Cytokine Pharmasciences Inc Guanylhydrazone die nützlich sind zur behandlung von mit t-zellen verbundenen krankheiten

Also Published As

Publication number Publication date
EP1255541B1 (de) 2005-11-09
AU2001240578A1 (en) 2001-08-14
WO2001056553A3 (en) 2002-03-28
DE60114772T2 (de) 2006-07-20
EP1255541A2 (de) 2002-11-13
DE60114772D1 (de) 2005-12-15
US20050171176A1 (en) 2005-08-04
US20030203969A1 (en) 2003-10-30
ES2250363T3 (es) 2006-04-16
WO2001056553A2 (en) 2001-08-09

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