AU1879792A - 4-aryl-3-(heteroarylureido)quinoline derivatives - Google Patents

4-aryl-3-(heteroarylureido)quinoline derivatives

Info

Publication number
AU1879792A
AU1879792A AU18797/92A AU1879792A AU1879792A AU 1879792 A AU1879792 A AU 1879792A AU 18797/92 A AU18797/92 A AU 18797/92A AU 1879792 A AU1879792 A AU 1879792A AU 1879792 A AU1879792 A AU 1879792A
Authority
AU
Australia
Prior art keywords
ureido
chlorophenyl
bis
quinoline
methylthio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU18797/92A
Other languages
English (en)
Inventor
Ernest S Hamanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of AU1879792A publication Critical patent/AU1879792A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
AU18797/92A 1991-04-26 1992-03-16 4-aryl-3-(heteroarylureido)quinoline derivatives Abandoned AU1879792A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69232391A 1991-04-26 1991-04-26
US692323 1991-04-26

Publications (1)

Publication Number Publication Date
AU1879792A true AU1879792A (en) 1992-12-21

Family

ID=24780107

Family Applications (1)

Application Number Title Priority Date Filing Date
AU18797/92A Abandoned AU1879792A (en) 1991-04-26 1992-03-16 4-aryl-3-(heteroarylureido)quinoline derivatives

Country Status (20)

Country Link
EP (1) EP0590094A1 (es)
JP (1) JPH0776215B2 (es)
CN (1) CN1066068A (es)
AU (1) AU1879792A (es)
BR (1) BR9205939A (es)
CA (1) CA2108014A1 (es)
CZ (1) CZ395592A3 (es)
DE (1) DE9290049U1 (es)
FI (1) FI934710A0 (es)
HU (1) HUT65748A (es)
IE (1) IE921330A1 (es)
IL (1) IL101627A0 (es)
MX (1) MX9201916A (es)
NO (1) NO933837L (es)
NZ (1) NZ242493A (es)
PT (1) PT100426A (es)
TW (1) TW197436B (es)
WO (1) WO1992019614A1 (es)
YU (1) YU44592A (es)
ZA (1) ZA922976B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0623112T3 (da) * 1992-01-23 1999-08-30 Pfizer 4-phenyl-3-(heteroarylureido)-1,2-dihydro-2-oxoquinolinderivater som antihypercholesterolæmiske og antiatherosclerotiske mi
US5565472A (en) * 1992-12-21 1996-10-15 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
NZ264063A (en) * 1993-08-13 1995-11-27 Nihon Nohyaku Co Ltd N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions
US5843957A (en) * 1995-05-19 1998-12-01 Sumitomo Pharmaceuticals Company, Ltd. Naphthyridine derivatives
KR100399798B1 (ko) * 1995-05-31 2004-05-31 스미또모 세이야꾸 가부시키가이샤 신규나프티리딘유도체
CN1245500A (zh) * 1996-11-26 2000-02-23 住友制药株式会社 新型萘啶衍生物
US6300500B1 (en) 1998-02-25 2001-10-09 Sumitomo Pharmaceuticals Company, Limited Preparation of pyridone derivatives using phthalimido containing starting material
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
KR20070001922A (ko) * 2003-12-12 2007-01-04 와이어쓰 심장혈관질환 치료에 유용한 퀴놀린
CN103601677B (zh) * 2013-11-19 2015-11-18 清华大学 制备2-烷硫基喹啉衍生物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
MX22406A (es) * 1989-09-15 1994-01-31 Pfizer Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat).
TW205037B (es) * 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
CZ395592A3 (en) 1994-02-16
FI934710A (fi) 1993-10-25
JPH06501025A (ja) 1994-01-27
CN1066068A (zh) 1992-11-11
JPH0776215B2 (ja) 1995-08-16
YU44592A (sh) 1994-12-28
BR9205939A (pt) 1994-09-27
MX9201916A (es) 1992-11-01
DE9290049U1 (de) 1994-01-05
NO933837L (no) 1993-10-25
IE921330A1 (en) 1992-11-04
HUT65748A (en) 1994-07-28
HU9303025D0 (en) 1994-01-28
EP0590094A1 (en) 1994-04-06
CA2108014A1 (en) 1992-10-27
FI934710A0 (fi) 1993-10-25
PT100426A (pt) 1993-08-31
TW197436B (es) 1993-01-01
WO1992019614A1 (en) 1992-11-12
ZA922976B (en) 1993-10-25
NZ242493A (en) 1994-08-26
IL101627A0 (en) 1992-12-30

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