ATE99314T1 - Verfahren zur herstellung von zweizaehnigen liganden. - Google Patents
Verfahren zur herstellung von zweizaehnigen liganden.Info
- Publication number
- ATE99314T1 ATE99314T1 AT88910206T AT88910206T ATE99314T1 AT E99314 T1 ATE99314 T1 AT E99314T1 AT 88910206 T AT88910206 T AT 88910206T AT 88910206 T AT88910206 T AT 88910206T AT E99314 T1 ATE99314 T1 AT E99314T1
- Authority
- AT
- Austria
- Prior art keywords
- independently selected
- cycloaliphatic
- aryl
- alkyl
- carbons
- Prior art date
Links
- 239000003446 ligand Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 2
- 125000002178 anthracenyl group Chemical group C1(=CC=CC2=CC3=CC=CC=C3C=C12)* 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- -1 e.g. Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000001624 naphthyl group Chemical group 0.000 abstract 2
- 125000005561 phenanthryl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 239000000376 reactant Substances 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000002816 nickel compounds Chemical class 0.000 abstract 1
- 239000003880 polar aprotic solvent Substances 0.000 abstract 1
- 238000006479 redox reaction Methods 0.000 abstract 1
- 150000003460 sulfonic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5027—Polyphosphines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/505—Preparation; Separation; Purification; Stabilisation
- C07F9/5063—Preparation; Separation; Purification; Stabilisation from compounds having the structure P-H or P-Heteroatom, in which one or more of such bonds are converted into P-C bonds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/118,573 US4879008A (en) | 1987-11-09 | 1987-11-09 | Preparation of bidentate ligands |
| EP88910206A EP0386105B1 (de) | 1987-11-09 | 1988-10-31 | Verfahren zur herstellung von zweizähnigen liganden |
| PCT/US1988/003852 WO1989004315A2 (en) | 1987-11-09 | 1988-10-31 | A process for the preparation of bidentate ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE99314T1 true ATE99314T1 (de) | 1994-01-15 |
Family
ID=22379435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88910206T ATE99314T1 (de) | 1987-11-09 | 1988-10-31 | Verfahren zur herstellung von zweizaehnigen liganden. |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US4879008A (de) |
| EP (1) | EP0386105B1 (de) |
| JP (1) | JP2801237B2 (de) |
| KR (2) | KR960002272B1 (de) |
| AT (1) | ATE99314T1 (de) |
| CA (1) | CA1326241C (de) |
| DE (1) | DE3886766T2 (de) |
| WO (1) | WO1989004315A2 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2005504C (en) * | 1988-12-22 | 1995-10-24 | Eastman Chemical Company | Preparation of bidentate ligands |
| JPH0733392B2 (ja) * | 1989-06-16 | 1995-04-12 | 高砂香料工業株式会社 | 2,2’―ビス〔ジー(m―トリル)ホスフィノ〕―1,1’―ビナフチル |
| DE4020184A1 (de) * | 1990-06-25 | 1992-01-02 | Hoechst Ag | Teilfluorierte biphenyle, verfahren zu ihrer herstellung und ihre verwendung |
| JPH0474192A (ja) * | 1990-07-12 | 1992-03-09 | Takasago Internatl Corp | 2,2′―ビス(ジシクロペンチルホスフィノ)―1,1′―ビナフチル及びこれれを配位子とする遷移金属錯体 |
| DE59309570D1 (de) * | 1992-01-31 | 1999-06-17 | Hoffmann La Roche | Diphosphinliganden |
| DE4433294A1 (de) * | 1993-11-13 | 1995-05-18 | Hoechst Ag | Verfahren zur Herstellung von Bis-(diaryl-alkyl)-phoshinen und neue Verbindungen aus dieser Stoffgruppe |
| US5399771A (en) * | 1994-06-01 | 1995-03-21 | Merck & Co., Inc. | Process of synthesizing binaphthyl derivatives |
| JP3789508B2 (ja) * | 1995-03-14 | 2006-06-28 | 高砂香料工業株式会社 | 光学活性非対称ジホスフィン及び該化合物の存在下にて光学活性体を得る方法 |
| US6333435B1 (en) | 1995-05-18 | 2001-12-25 | Merck & Co., Inc. | Process of synthesizing binaphthyl derivatives |
| EP0871621A4 (de) * | 1995-10-13 | 1999-10-13 | Penn State Res Found | Asymmetrische synthese die durch übergangsmetallkomplexe mit neuen liganden katalysiert wird |
| JP3441605B2 (ja) * | 1996-10-30 | 2003-09-02 | 高砂香料工業株式会社 | 新規光学活性ジホスフィン及び該化合物より得られる遷移金属錯体及び該錯体の存在下にて光学活性体を得る方法 |
| US5874628A (en) * | 1997-03-26 | 1999-02-23 | Monsanto Company | Method for preparation of tertiary phosphines via nickel-catalyzed cross coupling |
| US6162929A (en) * | 1997-12-23 | 2000-12-19 | Hoffmann-La Roche Inc. | Process for the manufacture of bisphosphine oxide and bisphosphonate compounds |
| GB9805348D0 (en) * | 1998-03-16 | 1998-05-06 | Ici Plc | Compound |
| US20020131972A1 (en) * | 1998-05-21 | 2002-09-19 | Daniel Sem | Multi-partite ligands and methods of identifying and using same |
| US7653490B2 (en) | 2001-09-10 | 2010-01-26 | Triad Liquidating Company LLC | Nuclear magnetic resonance assembly of chemical entities |
| US8513468B2 (en) | 2010-12-30 | 2013-08-20 | Eastman Chemical Company | Process for removing degradation acids from hydroformylation reactions |
| CN102875598B (zh) * | 2011-07-11 | 2016-09-07 | 深圳市有为化学技术有限公司 | (二苯膦氧基)(均三甲苯基)甲酮和(苯膦氧基)双(均三甲苯基甲酮)的制备方法 |
| CN109928987B (zh) * | 2017-12-19 | 2021-12-21 | 北京颖泰嘉和生物科技有限公司 | 制备邻氯苄基氯化镁类化合物的方法 |
| CN111138461B (zh) * | 2019-12-05 | 2023-01-20 | 海利尔药业集团股份有限公司 | 一种邻氯苄氯格氏试剂的连续化制备方法 |
| CN113912646B (zh) * | 2021-11-18 | 2024-05-17 | 浙江新化化工股份有限公司 | 一种双齿膦配体的制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3239566A (en) * | 1960-07-22 | 1966-03-08 | Shell Oil Co | Hydroformylation of olefins |
| US3539622A (en) * | 1966-12-23 | 1970-11-10 | Hercules Inc | Process for producing diaryl compounds |
| US3527809A (en) * | 1967-08-03 | 1970-09-08 | Union Carbide Corp | Hydroformylation process |
| US3748350A (en) * | 1969-12-29 | 1973-07-24 | Hercules Inc | Coupling with a palladium salt |
| US3636168A (en) * | 1969-12-29 | 1972-01-18 | Hercules Inc | Preparation of polynuclear aromatic compounds |
| US4138420A (en) * | 1976-01-19 | 1979-02-06 | Celanese Corporation | Hydroformylation catalysts |
| US4193943A (en) * | 1976-01-19 | 1980-03-18 | Celanese Corporation | Hydroformylation catalysts |
| US4026957A (en) * | 1976-04-30 | 1977-05-31 | Iowa State University Research Foundation, Inc. | Symmetrical conjugated diene and polyene synthesis via vinylmercuric salts |
| US4139565A (en) * | 1977-03-31 | 1979-02-13 | Celanese Corporation | Hydroformylation using improved catalysts comprising rhodium and diphosphino ligands |
| US4152344A (en) * | 1977-08-08 | 1979-05-01 | Celanese Corporation | Phosphino-ferrocene ligands |
| US4201728A (en) * | 1977-08-19 | 1980-05-06 | Celanese Corporation | Hydroformylation catalyst and process |
| US4169861A (en) * | 1977-08-19 | 1979-10-02 | Celanese Corporation | Hydroformylation process |
| JPS5439059A (en) * | 1977-08-26 | 1979-03-24 | Nitto Riken Kogyo Kk | Production and use of novel phosphine compound |
| JPS54119407A (en) * | 1978-03-09 | 1979-09-17 | Agency Of Ind Science & Technol | Preparation of aldehydes |
| US4263466A (en) * | 1978-10-30 | 1981-04-21 | Union Carbide Corporation | Coupling of aryl and heteroaryl mono chlorides |
| US4221744A (en) * | 1978-12-01 | 1980-09-09 | Celanese Corporation | Hydroformylation process employing rhodium-based catalysts comprising ligands having electronegative substituents |
| US4326989A (en) * | 1979-09-11 | 1982-04-27 | Union Carbide Corporation | Catalyst of nickel compound and ligand in presence of a reducing metal |
| US4694109A (en) * | 1986-06-13 | 1987-09-15 | Eastman Kodak Company | Chelate ligands for low pressure hydroformylation catalyst and process employing same |
| US4760194A (en) * | 1987-02-18 | 1988-07-26 | Eastman Kodak Company | Low pressure hydroformylation catalyst employing unique ligands and process using same |
-
1987
- 1987-11-09 US US07/118,573 patent/US4879008A/en not_active Expired - Lifetime
-
1988
- 1988-10-24 CA CA000581076A patent/CA1326241C/en not_active Expired - Fee Related
- 1988-10-31 KR KR1019950704538A patent/KR960002272B1/ko not_active Expired - Fee Related
- 1988-10-31 WO PCT/US1988/003852 patent/WO1989004315A2/en not_active Ceased
- 1988-10-31 KR KR1019890701274A patent/KR960002274B1/ko not_active Expired - Fee Related
- 1988-10-31 EP EP88910206A patent/EP0386105B1/de not_active Expired - Lifetime
- 1988-10-31 DE DE3886766T patent/DE3886766T2/de not_active Expired - Lifetime
- 1988-10-31 JP JP63509391A patent/JP2801237B2/ja not_active Expired - Lifetime
- 1988-10-31 AT AT88910206T patent/ATE99314T1/de not_active IP Right Cessation
-
1989
- 1989-07-24 US US07/383,696 patent/US4956055A/en not_active Expired - Lifetime
- 1989-07-24 US US07/383,697 patent/US4954227A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE3886766D1 (de) | 1994-02-10 |
| JP2801237B2 (ja) | 1998-09-21 |
| WO1989004315A3 (en) | 1989-06-01 |
| DE3886766T2 (de) | 1994-07-28 |
| US4879008A (en) | 1989-11-07 |
| KR890701602A (ko) | 1989-12-21 |
| KR960002274B1 (ko) | 1996-02-14 |
| KR960002272B1 (ko) | 1996-02-14 |
| US4956055A (en) | 1990-09-11 |
| JPH03500881A (ja) | 1991-02-28 |
| US4954227A (en) | 1990-09-04 |
| EP0386105A1 (de) | 1990-09-12 |
| CA1326241C (en) | 1994-01-18 |
| WO1989004315A2 (en) | 1989-05-18 |
| EP0386105B1 (de) | 1993-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEIH | Change in the person of patent owner | ||
| REN | Ceased due to non-payment of the annual fee |