ATE99176T1 - Transdermales arzneimittelabgabesytem auf der grundlage eines multipolymers. - Google Patents

Transdermales arzneimittelabgabesytem auf der grundlage eines multipolymers.

Info

Publication number
ATE99176T1
ATE99176T1 AT89903629T AT89903629T ATE99176T1 AT E99176 T1 ATE99176 T1 AT E99176T1 AT 89903629 T AT89903629 T AT 89903629T AT 89903629 T AT89903629 T AT 89903629T AT E99176 T1 ATE99176 T1 AT E99176T1
Authority
AT
Austria
Prior art keywords
multipolymer
drug
dermal
polymer
delivery system
Prior art date
Application number
AT89903629T
Other languages
English (en)
Inventor
Steven Sablotsky
John M Questel
Dorothy J Leeson
Original Assignee
Noven Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noven Pharma filed Critical Noven Pharma
Application granted granted Critical
Publication of ATE99176T1 publication Critical patent/ATE99176T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive bandages or dressings
    • A61F13/0276Apparatus or processes for manufacturing adhesive dressings or bandages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7076Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/58Adhesives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B26HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26FPERFORATING; PUNCHING; CUTTING-OUT; STAMPING-OUT; SEVERING BY MEANS OTHER THAN CUTTING
    • B26F1/00Perforating; Punching; Cutting-out; Stamping-out; Apparatus therefor
    • B26F1/38Cutting-out; Stamping-out
    • B26F1/384Cutting-out; Stamping-out using rotating drums

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Botany (AREA)
  • Manufacturing & Machinery (AREA)
  • Vascular Medicine (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
AT89903629T 1988-03-04 1989-02-21 Transdermales arzneimittelabgabesytem auf der grundlage eines multipolymers. ATE99176T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/164,482 US4814168A (en) 1988-03-04 1988-03-04 Transdermal multipolymer drug delivery system
PCT/US1989/000678 WO1989007950A1 (en) 1988-03-04 1989-02-21 Transdermal multipolymer drug delivery system

Publications (1)

Publication Number Publication Date
ATE99176T1 true ATE99176T1 (de) 1994-01-15

Family

ID=22594693

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89903629T ATE99176T1 (de) 1988-03-04 1989-02-21 Transdermales arzneimittelabgabesytem auf der grundlage eines multipolymers.

Country Status (11)

Country Link
US (1) US4814168A (de)
EP (1) EP0418248B1 (de)
JP (1) JP2659837B2 (de)
KR (1) KR950013461B1 (de)
AT (1) ATE99176T1 (de)
AU (1) AU606840B2 (de)
CA (1) CA1338660C (de)
DE (1) DE68911920T2 (de)
DK (1) DK174994B1 (de)
FI (1) FI104618B (de)
WO (1) WO1989007950A1 (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993004677A1 (fr) * 1991-08-30 1993-03-18 Hisamitsu Pharmaceutical Co., Inc. Sparadrap analgesique anti-inflammatoire
US5560922A (en) * 1986-05-30 1996-10-01 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process
JPH0696529B2 (ja) * 1987-03-31 1994-11-30 積水化学工業株式会社 ニトログリセリン貼付剤およびその製造方法
US5300291A (en) * 1988-03-04 1994-04-05 Noven Pharmaceuticals, Inc. Method and device for the release of drugs to the skin
US5656286A (en) 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5474783A (en) * 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US4994267A (en) * 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
JPH0725669B2 (ja) * 1988-12-23 1995-03-22 日東電工株式会社 経皮投与用医薬製剤
US5147916A (en) * 1990-02-21 1992-09-15 Dow Corning Corporation Hot-melt silicone pressure sensitive adhesive composition and related methods and articles
DK0474647T3 (da) * 1990-03-28 1997-08-18 Noven Pharma Fremgangsmåde og indretning til frigivelse af lægemidler til huden
DE69115471T2 (de) * 1990-03-30 1996-05-02 Alza Corp., Palo Alto, Calif. Gerät zur iontophoretischen verabreichung von medikamenten
US5383848A (en) * 1990-04-12 1995-01-24 Gensia, Inc. Iontophoretic administration of drugs
US5162410A (en) * 1990-04-13 1992-11-10 Dow Corning Corporation Hot-melt silicon pressure sensitive adhesives with phenyl-containing siloxane fluid additive and related methods and articles
US5202125A (en) * 1990-12-10 1993-04-13 Theratech, Inc. Method and systems for administering nitroglycerin transdermally at enhanced transdermal fluxes
CA2109956C (en) * 1991-06-10 1998-05-05 Dieter Beutner Nitroglycerine plaster and process for making it
US5705185A (en) * 1991-09-25 1998-01-06 Beta Pharmaceuticals Co. Transdermal delivery of estradiol and process for manufacturing said device
US5352456A (en) * 1991-10-10 1994-10-04 Cygnus Therapeutic Systems Device for administering drug transdermally which provides an initial pulse of drug
US5496819A (en) * 1991-11-15 1996-03-05 Ss Pharmaceutical Co., Ltd. Antiphlogistic-analgesic plaster comprising triacetin and piroxicam
DE4226753A1 (de) * 1992-08-13 1994-02-17 Basf Ag Wirkstoffe enthaltende Zubereitungen in Form fester Teilchen
DE4230588C1 (de) * 1992-09-12 1993-10-07 Lohmann Therapie Syst Lts Dexpanthenol-haltiges Pflaster zur transdermalen Applikation von Steroidhormonen und Verfahren zu seiner Herstellung
GB2273044B (en) * 1992-12-02 1997-04-09 Pacific Chem Co Ltd Medicinal patches for percutaneous administration
US5427585A (en) * 1993-03-29 1995-06-27 Bettinger; David S. On-demand iontophoretic system
US5762952A (en) * 1993-04-27 1998-06-09 Hercon Laboratories Corporation Transdermal delivery of active drugs
BR9401951A (pt) * 1994-05-11 1995-12-05 Alba Quimica Ind E Com Ltda Adesivo de contato à base de água
US5498417A (en) * 1994-05-12 1996-03-12 Coating Sciences, Inc. Transdermal delivery of appetite suppressant drug
NZ309980A (en) * 1995-06-07 2001-06-29 Noven Pharma Transdermal composition containing a blend of one or more polymers, one or more drugs that has a low molecular weight and is liquid at room temperature
US6572879B1 (en) * 1995-06-07 2003-06-03 Alza Corporation Formulations for transdermal delivery of pergolide
US6316022B1 (en) * 1995-06-07 2001-11-13 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
DE19650471A1 (de) * 1996-12-05 1998-06-10 Beiersdorf Ag Wirkstoffhaltige Pflaster
US5948433A (en) * 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
GB9720470D0 (en) 1997-09-25 1997-11-26 Ethical Pharmaceuticals South Inhibition of crystallization in transdermal devices
EP1105110B1 (de) * 1998-08-20 2006-10-25 3M Innovative Properties Company Sprühverband und wirkstoffabgabesystem
CA2358448C (en) 1998-12-30 2009-02-10 Dexcel Ltd. Dispersible concentrate for the delivery of cyclosporin
US6337086B1 (en) 1999-02-06 2002-01-08 Dow Corning Corporation Pressure sensitive adhesive compositions for transdermal drug delivery devices
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
US6905016B2 (en) 2000-03-14 2005-06-14 Noven Pharmaceuticals, Inc. Packaging system for transdermal drug delivery systems
KR100940245B1 (ko) * 2000-09-19 2010-02-04 내쇼날 스타치 앤드 케미칼 인베스트멘트 홀딩 코포레이션 경피 약물 전달 시스템에 유용한 비반응성 접착제
US7988991B2 (en) * 2001-03-07 2011-08-02 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch
DE10118282A1 (de) * 2001-04-12 2002-12-05 Lohmann Therapie Syst Lts Haftkleber auf Basis von Ethylen-Vinylacetat-Copolymeren und Klebharzen, für medizinische Verwendungszwecke
US20040131873A1 (en) * 2003-01-08 2004-07-08 Jiangbo Ouyang Pressure sensitive adhesive composition containing ethylene/vinyl ester functional copolymers having high ethylene content
JP2005325165A (ja) * 2004-05-12 2005-11-24 Three M Innovative Properties Co 100℃以下の温度で溶融塗布可能なヨウ素含有ホットメルト粘着剤および該粘着剤を用いた医療用粘着シート製品
US20060127463A1 (en) * 2004-12-15 2006-06-15 Nugara Peter N Composite structure including a low vinyl acetate layer
US20090214643A1 (en) * 2005-07-19 2009-08-27 Franklin Amie E Improved pharmacokinetic profile of beta-adrenergic inverse agonists for the treatment of pulmonary airway diseases
RU2008138595A (ru) * 2006-02-27 2010-04-10 Ноувен Фамэсьютикэлз, Инк. (US) Гибкая ограниченная система для трансдермального введения скополамина, способ ее изготовления и способ трансдермальной доставки скополамина с ее помощью
US20070287727A1 (en) * 2006-06-08 2007-12-13 Jacob Hiller Anti-Nicotine Treatment
US20080226698A1 (en) * 2007-03-16 2008-09-18 Mylan Technologies, Inc. Amorphous drug transdermal systems, manufacturing methods, and stabilization
US20090048296A1 (en) * 2007-08-17 2009-02-19 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
US8231906B2 (en) 2008-07-10 2012-07-31 Noven Pharmaceuticals, Inc. Transdermal estrogen device and delivery
US8119694B2 (en) * 2008-08-15 2012-02-21 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
AU2009302853B2 (en) * 2008-10-06 2014-09-11 Mylan Technologies, Inc. Amorphous rotigotine transdermal system
DE102011114411A1 (de) * 2011-09-26 2013-03-28 Lts Lohmann Therapie-Systeme Ag Pflaster mit einstellbarer Okklusion
FR2984906B1 (fr) * 2011-12-26 2014-02-28 Bostik Sa Composition de colle pelable
TW201431570A (zh) 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀(Rotigotine)之多天式貼片
US20140288481A1 (en) * 2013-03-15 2014-09-25 G. Chad MORGAN Transdermal patch with non-water soluble adhesive and anesthetic
JP6726096B2 (ja) 2013-07-03 2020-07-22 エルテーエス ローマン テラピー−システメ アーゲー 電子部品を有する経皮治療システム
CA2948219C (en) 2014-05-20 2023-04-04 Lts Lohmann Therapie-Systeme Ag Method for adjusting the release of active agent in a transdermal delivery system
EP3145502B1 (de) 2014-05-20 2022-07-06 LTS Lohmann Therapie-Systeme AG Transdermales abgabesystem mit rotigotin
ES2954087T3 (es) 2014-05-20 2023-11-20 Lts Lohmann Therapie Systeme Ag Sistema de administración transdérmica que incluye un mediador de interfase
FR3021973B1 (fr) * 2014-06-05 2016-07-01 Bostik Sa Composition de colle pelable
US10406116B2 (en) 2015-02-06 2019-09-10 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
HK1248265B (en) 2015-02-06 2020-04-03 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
KR102033243B1 (ko) * 2017-07-31 2019-10-17 이민희 아로마테라피 기능성 발열팩 및 그 제조방법
MX2021012933A (es) * 2019-04-24 2021-12-15 Medrx Co Ltd Parche que contiene lidocaina.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144317A (en) * 1975-05-30 1979-03-13 Alza Corporation Device consisting of copolymer having acetoxy groups for delivering drugs
JPS56133381A (en) * 1980-03-25 1981-10-19 Nippon Kayaku Co Ltd Pressure-sensitive adhesive tape or sheet containing nitroglycerin
JPS6059207B2 (ja) * 1981-03-13 1985-12-24 日東電工株式会社 複合製剤の製法
JPS57181020A (en) * 1981-04-30 1982-11-08 Kao Corp Poultice base composition
JPS57209217A (en) * 1981-06-17 1982-12-22 Nitto Electric Ind Co Ltd Medicament preparation
GB2105990B (en) * 1981-08-27 1985-06-19 Nitto Electric Ind Co Adhesive skin patches
JPS615012A (ja) * 1984-06-11 1986-01-10 Dai Ichi Seiyaku Co Ltd 貼付剤
US4704282A (en) * 1984-06-29 1987-11-03 Alza Corporation Transdermal therapeutic system having improved delivery characteristics
US4725439A (en) * 1984-06-29 1988-02-16 Alza Corporation Transdermal drug delivery device
ATE95430T1 (de) * 1984-12-22 1993-10-15 Sanol Arznei Schwarz Gmbh Wirkstoffpflaster.
EP0223524B1 (de) * 1985-11-08 1991-10-23 Nitto Denko Corporation Verwendung von Heftpflastern für die Haut und perkutanen Präparaten
US4743249A (en) * 1986-02-14 1988-05-10 Ciba-Geigy Corp. Dermal and transdermal patches having a discontinuous pattern adhesive layer
FR2612785A1 (fr) * 1987-03-25 1988-09-30 Lhd Lab Hygiene Dietetique Dispositif auto-adhesif d'administration d'un principe actif par voie percutanee

Also Published As

Publication number Publication date
DE68911920D1 (de) 1994-02-10
AU3284789A (en) 1989-09-22
EP0418248B1 (de) 1993-12-29
KR900700141A (ko) 1990-08-11
FI104618B (fi) 2000-03-15
HK1006285A1 (en) 1999-02-19
KR950013461B1 (ko) 1995-11-08
JP2659837B2 (ja) 1997-09-30
FI904358A0 (fi) 1990-09-04
EP0418248A1 (de) 1991-03-27
DE68911920T2 (de) 1994-07-07
AU606840B2 (en) 1991-02-14
JPH03503283A (ja) 1991-07-25
DK549489A (da) 1989-11-29
DK549489D0 (da) 1989-11-03
DK174994B1 (da) 2004-04-13
US4814168A (en) 1989-03-21
CA1338660C (en) 1996-10-22
WO1989007950A1 (en) 1989-09-08

Similar Documents

Publication Publication Date Title
ATE99176T1 (de) Transdermales arzneimittelabgabesytem auf der grundlage eines multipolymers.
DE69019175D1 (de) Transdermales Arzneimittelabgabesystem auf der Grundlage eines Acrylmultipolymers.
US4865848A (en) Skin permeation enhancer compositions using sucrose esters
US4940586A (en) Skin permeation enhancer compositions using sucrose esters
US4900555A (en) Skin permeation enhancer compositions using sucrose esters
US4746515A (en) Skin permeation enhancer compositions using glycerol monolaurate
JP2588180B2 (ja) 皮膚浸透ニトログリセリン投薬系
NO883591L (no) Dermal administrasjonsform.
KR900701242A (ko) 에스트라디올의 경피전달용 조성물
DK0429039T3 (da) Anvendelse af en opiat-antagonist til fremstilling af en farmaceutisk sammensætning, der skal indgives transdermalt, samt organ til transdermal afgivelse
ATE42901T1 (de) Haftendes arzneimittelpraeparat fuer perkutane absorption.
DK0488137T3 (da) Præparat til transdermal medikamentadministrering
MY106628A (en) Estrogen-containing active substance plaster
FI920960A0 (fi) Fast matrissystem foer transdermal dosering av laekemedelsaemnen.
NL970007I1 (nl) Transdermaal oestradiotoedieningssysteem.
IL106512A (en) Plaster for the transdermal application of steroid hormones and process for the preparation thereof
DE3789288D1 (de) Basische, wirkstoffdurchlässige haftklebende Polymermasse, Verfahren zu ihrer Herstellung und ihre Verwendung.
PL319259A1 (en) Scopolamine containing plaster
JPH01299217A (ja) 硬膏剤
KR910009259A (ko) 천식 또는 특정 피부 질환의 치료를 위한 피리미돈 유도체 및 동족체
NO952908L (no) Nitroglycerolholdig plaster, fremgangsmåte for fremstilling, samt anvendelse av plasteret
JP3218473B2 (ja) 角質軟化硬膏剤
JPH10316825A (ja) 粘着性組成物
JPS5942314A (ja) 外用部材

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time