ATE96664T1 - Nicht-beta-oxidierbare fettsaeure-analoge, die die blutkonzentration von cholesterin und triglyceriden bei saeugetieren senken. - Google Patents
Nicht-beta-oxidierbare fettsaeure-analoge, die die blutkonzentration von cholesterin und triglyceriden bei saeugetieren senken.Info
- Publication number
- ATE96664T1 ATE96664T1 AT89305478T AT89305478T ATE96664T1 AT E96664 T1 ATE96664 T1 AT E96664T1 AT 89305478 T AT89305478 T AT 89305478T AT 89305478 T AT89305478 T AT 89305478T AT E96664 T1 ATE96664 T1 AT E96664T1
- Authority
- AT
- Austria
- Prior art keywords
- triglycerides
- cholesterol
- mammals
- beta
- fatty acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888813012A GB8813012D0 (en) | 1988-06-02 | 1988-06-02 | Non-b-oxidizable fatty acid analogues to reduce concentration of cholesterol & triglycerides in blood of mammals |
EP89305478A EP0345038B1 (de) | 1988-06-02 | 1989-05-31 | Nicht-beta-oxidierbare Fettsäure-Analoge, die die Blutkonzentration von Cholesterin und Triglyceriden bei Säugetieren senken |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE96664T1 true ATE96664T1 (de) | 1993-11-15 |
Family
ID=10637920
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT89305478T ATE96664T1 (de) | 1988-06-02 | 1989-05-31 | Nicht-beta-oxidierbare fettsaeure-analoge, die die blutkonzentration von cholesterin und triglyceriden bei saeugetieren senken. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5093365A (de) |
EP (1) | EP0345038B1 (de) |
AT (1) | ATE96664T1 (de) |
CA (1) | CA1329550C (de) |
DE (1) | DE68910386T2 (de) |
DK (1) | DK267689A (de) |
ES (1) | ES2059749T3 (de) |
GB (1) | GB8813012D0 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100463709B1 (ko) * | 1994-10-13 | 2005-08-04 | 위민스 앤드 칠드런스 호스피털 애드레이드 | 변형된불포화지방산 |
NO952796D0 (no) * | 1995-07-14 | 1995-07-14 | Rolf Berge | Fettsyre analoger med ikkeoksyderbart B-sete, fremstilling og anvendelse i krapeutiske preparater |
AU7240398A (en) * | 1998-05-08 | 1999-11-29 | Rolf Berge | Use of non-beta-oxidizable fatty acid analogues for treatment of syndrome-x conditions |
US20020074691A1 (en) * | 1999-09-14 | 2002-06-20 | Robert M Mortellite | High speed method of making plastic film and nonwoven laminates |
AUPQ291499A0 (en) * | 1999-09-17 | 1999-10-07 | Women's And Children's Hospital Adelaide | Novel nitro and sulphur containing compounds |
NO328803B1 (no) | 2000-03-03 | 2010-05-18 | Thia Medica | Nye fettsyreanaloger |
US6982251B2 (en) * | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
EP1911462A3 (de) | 2001-01-26 | 2011-11-30 | Schering Corporation | Zusammensetzungen enthaltend einen Sterolabsorptionshemmer |
JP2004521894A (ja) * | 2001-01-26 | 2004-07-22 | シェーリング コーポレイション | 胆汁酸金属イオン封鎖剤およびステロール吸収阻害剤の併用および血管適応症の治療 |
CA2434488A1 (en) * | 2001-01-26 | 2002-08-01 | Harry R. Davis | Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications |
WO2002058696A2 (en) * | 2001-01-26 | 2002-08-01 | Schering Corporation | The use of substituted azetidinone compounds for the treatment of sitosterolemia |
US7071181B2 (en) * | 2001-01-26 | 2006-07-04 | Schering Corporation | Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors |
DK1353694T3 (da) * | 2001-01-26 | 2008-03-25 | Schering Corp | Kombinationer af ezetimibe med aspirin til behandling af vaskulære tilstande |
AU2002247019C1 (en) * | 2001-01-26 | 2017-05-11 | Organon Llc | Combinations of peroxisome proliferator-activated receptor (PPAR) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications |
EP1541175A3 (de) * | 2001-01-26 | 2006-04-12 | Schering Corporation | Kombinationen von einem Hemmer der Sterol-Absorption und einem kardiovaskular Agent zur Behandlung von kardiovaskulären Indikationen |
US20060287254A1 (en) * | 2001-01-26 | 2006-12-21 | Schering Corporation | Use of substituted azetidinone compounds for the treatment of sitosterolemia |
ATE345792T1 (de) * | 2001-05-25 | 2006-12-15 | Schering Corp | Verwendung von mit azetidinon substituierten derivaten bei der behandlung der alzheimer- krankheit |
FR2828487B1 (fr) * | 2001-08-09 | 2005-05-27 | Genfit S A | Nouveaux composes derives d'acides gras, preparation et utilisations |
HUP0401501A3 (en) * | 2001-09-21 | 2012-02-28 | Schering Corp | Treating or preventing vascular inflammation using pharmaceutical compositions containing sterol absorption inhibitor(s) |
US7056906B2 (en) * | 2001-09-21 | 2006-06-06 | Schering Corporation | Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women |
US20030119808A1 (en) * | 2001-09-21 | 2003-06-26 | Schering Corporation | Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects |
US7053080B2 (en) * | 2001-09-21 | 2006-05-30 | Schering Corporation | Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors |
WO2003026643A2 (en) * | 2001-09-21 | 2003-04-03 | Schering Corporation | Treatment of xanthoma with azetidinone derivatives as sterol absorption inhibitors |
CA2490121C (en) * | 2002-06-20 | 2013-01-08 | Ic Vec Limited | Modified phospholipids |
US20040067267A1 (en) * | 2002-10-08 | 2004-04-08 | Murthy Pothapragada Suryanarayana | Process for preparation of cholesterol lowering compositions from garlic |
MXPA05004810A (es) * | 2002-11-06 | 2005-07-22 | Schering Corp | Inhibidores de la absorcion del colesterol para el tratamiento de la desmielinizacion. |
US7459442B2 (en) * | 2003-03-07 | 2008-12-02 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
EP1601669B1 (de) * | 2003-03-07 | 2008-12-24 | Schering Corporation | Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia |
US7192944B2 (en) | 2003-03-07 | 2007-03-20 | Schering Corp. | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
ES2311806T3 (es) * | 2003-03-07 | 2009-02-16 | Schering Corporation | Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
WO2005046797A2 (en) * | 2003-11-05 | 2005-05-26 | Schering Corporation | Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions |
EP1718602A4 (de) * | 2004-01-30 | 2007-12-12 | Peplin Biolipids Pty Ltd | Therapeutische und trägermoleküle |
MX2007000816A (es) * | 2004-07-19 | 2007-06-05 | Thia Medica As | Composicion que comprende material de proteina y compuestos que comprenden entidades de acido graso no oxidable. |
US20130156720A1 (en) | 2010-08-27 | 2013-06-20 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
AU2014229506B2 (en) | 2013-03-11 | 2017-04-13 | Nobesita As | Natural lipids containing non-oxidizable fatty acids |
EP2983658B1 (de) | 2013-03-11 | 2024-05-01 | Sciadonics, Inc. | Lipidzusammensetzungen mit bioaktiven fettsäuren |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2208533A1 (de) * | 1972-02-23 | 1973-09-27 | Kolmar Laboratories | Neue alkylthioaether |
NL7405744A (en) * | 1974-04-29 | 1975-10-31 | Dow Chemical Co | Butylphenyl-thioalkane carboxylic acids - as hypocholesterolaemics and antilipaemics from corresp. thiophenols and haloalkane carboxylic acids |
DE2515146A1 (de) * | 1975-04-08 | 1976-10-21 | Bayer Ag | Carbonsaeureamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
DE2856683A1 (de) * | 1978-12-29 | 1980-07-17 | Nattermann A & Cie | Entzuendungshemmende und antiatherosklerotisch wirkende arzneimittel |
CH661207A5 (en) * | 1980-06-30 | 1987-07-15 | Hoerrmann Wilhelm | Pharmaceutical composition containing long-chain aldehydes or carboxylic acids |
-
1988
- 1988-06-02 GB GB888813012A patent/GB8813012D0/en active Pending
-
1989
- 1989-05-31 AT AT89305478T patent/ATE96664T1/de not_active IP Right Cessation
- 1989-05-31 DE DE68910386T patent/DE68910386T2/de not_active Expired - Lifetime
- 1989-05-31 EP EP89305478A patent/EP0345038B1/de not_active Expired - Lifetime
- 1989-05-31 ES ES89305478T patent/ES2059749T3/es not_active Expired - Lifetime
- 1989-06-01 CA CA000601425A patent/CA1329550C/en not_active Expired - Lifetime
- 1989-06-01 DK DK267689A patent/DK267689A/da not_active Application Discontinuation
- 1989-06-02 US US07/360,870 patent/US5093365A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5093365A (en) | 1992-03-03 |
EP0345038A2 (de) | 1989-12-06 |
ES2059749T3 (es) | 1994-11-16 |
DK267689A (da) | 1989-12-03 |
EP0345038B1 (de) | 1993-11-03 |
CA1329550C (en) | 1994-05-17 |
DE68910386D1 (de) | 1993-12-09 |
EP0345038A3 (de) | 1991-06-12 |
DE68910386T2 (de) | 1994-06-09 |
GB8813012D0 (en) | 1988-07-06 |
DK267689D0 (da) | 1989-06-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |