ATE88890T1 - D-cycloserin und d-alanin enthaltende mischung zur verbesserung des gedaechtnisses und des lernvermoegens oder zur behandlung von kognitiven und psychotischen erkrankungen. - Google Patents

D-cycloserin und d-alanin enthaltende mischung zur verbesserung des gedaechtnisses und des lernvermoegens oder zur behandlung von kognitiven und psychotischen erkrankungen.

Info

Publication number
ATE88890T1
ATE88890T1 AT90104875T AT90104875T ATE88890T1 AT E88890 T1 ATE88890 T1 AT E88890T1 AT 90104875 T AT90104875 T AT 90104875T AT 90104875 T AT90104875 T AT 90104875T AT E88890 T1 ATE88890 T1 AT E88890T1
Authority
AT
Austria
Prior art keywords
learning
cycloserin
mixture containing
improve memory
treat cognitive
Prior art date
Application number
AT90104875T
Other languages
German (de)
English (en)
Inventor
Alexis A Cordi
Michael R Jans
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of ATE88890T1 publication Critical patent/ATE88890T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
AT90104875T 1989-03-15 1990-03-15 D-cycloserin und d-alanin enthaltende mischung zur verbesserung des gedaechtnisses und des lernvermoegens oder zur behandlung von kognitiven und psychotischen erkrankungen. ATE88890T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32427989A 1989-03-15 1989-03-15
US07/473,241 US5061721A (en) 1989-03-15 1990-02-06 Composition containing d-cycloserine and d-alanine for memory and learning enhancement or treatment of a cognitive or psychotic disorder

Publications (1)

Publication Number Publication Date
ATE88890T1 true ATE88890T1 (de) 1993-05-15

Family

ID=26984373

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90104875T ATE88890T1 (de) 1989-03-15 1990-03-15 D-cycloserin und d-alanin enthaltende mischung zur verbesserung des gedaechtnisses und des lernvermoegens oder zur behandlung von kognitiven und psychotischen erkrankungen.

Country Status (17)

Country Link
US (1) US5061721A (cg-RX-API-DMAC7.html)
EP (1) EP0387867B1 (cg-RX-API-DMAC7.html)
JP (1) JP2963720B2 (cg-RX-API-DMAC7.html)
KR (1) KR900013961A (cg-RX-API-DMAC7.html)
AT (1) ATE88890T1 (cg-RX-API-DMAC7.html)
AU (1) AU624917B2 (cg-RX-API-DMAC7.html)
CA (1) CA2010635C (cg-RX-API-DMAC7.html)
DE (1) DE69001503T2 (cg-RX-API-DMAC7.html)
DK (1) DK0387867T3 (cg-RX-API-DMAC7.html)
ES (1) ES2055197T3 (cg-RX-API-DMAC7.html)
FI (1) FI901289A7 (cg-RX-API-DMAC7.html)
GR (1) GR3008225T3 (cg-RX-API-DMAC7.html)
IE (1) IE64130B1 (cg-RX-API-DMAC7.html)
IL (1) IL93562A (cg-RX-API-DMAC7.html)
NO (1) NO901198L (cg-RX-API-DMAC7.html)
NZ (1) NZ232809A (cg-RX-API-DMAC7.html)
PT (1) PT93424B (cg-RX-API-DMAC7.html)

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US5523323A (en) * 1993-09-14 1996-06-04 Maccecchini; Maria-Luisa Use of partial agonists of the NMDA receptor to reduce opiate induced tolerance and dependence
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DE69614835T2 (de) * 1995-02-15 2002-04-25 Annovis, Inc. Alkylcarboxy-aminosäure modulatoren für den kainat-rezeptor
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US6277825B1 (en) 1996-07-22 2001-08-21 University Of Utah Research Foundation Use of conantokins for treating pain
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US6551993B1 (en) * 1999-08-16 2003-04-22 Thomas Jefferson University Partial agonists at the glycine modulatory site of the NMDA receptor for treating cognitive dysfunction
US6399574B1 (en) 2000-03-22 2002-06-04 University Of Utah Research Foundation Use of conantokins
US20040122090A1 (en) * 2001-12-07 2004-06-24 Lipton Stuart A. Methods for treating neuropsychiatric disorders with nmda receptor antagonists
US20050096396A1 (en) * 2002-03-28 2005-05-05 Emory University Acute pharmacologic augmentation of psychotherapy with enhancers of learning or conditioning
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CN1527813A (zh) * 2001-04-02 2004-09-08 О 作为治疗剂的抗氧化剂硝基氧和亚硝氮碳基
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US20050176826A1 (en) * 2002-03-15 2005-08-11 H. Lundbeck A/S Use of asc-1 inhibitors to treat neurological and psychiatric disorders
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US20070010573A1 (en) 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
US7244764B2 (en) 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
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WO2005065308A2 (en) 2003-12-29 2005-07-21 Jason Mcdevitt Compositions and methods to treat recurrent medical conditions
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US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
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PL1874282T3 (pl) 2005-04-06 2011-04-29 Adamas Pharmaceuticals Inc Sposoby i kompozycje do leczenia zaburzeń OUN
TW200716088A (en) 2005-04-15 2007-05-01 Neurochem Int Ltd Formulations and methods for treating amyloidosis
JP5607930B2 (ja) 2006-10-12 2014-10-15 ビーエイチアイ リミテッド パートナーシップ 3−アミノ−1−プロパンスルホン酸を送達するための方法、化合物、組成物および媒体
WO2008124814A2 (en) * 2007-04-10 2008-10-16 Mcdevitt Jason P Sublingual formulations of d-cycloserine and methods of using same
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KR101692275B1 (ko) 2010-02-11 2017-01-04 노오쓰웨스턴 유니버시티 2차 구조 안정화된 nmda 수용체 조절제 및 그의 용도
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JP5689026B2 (ja) * 2010-06-17 2015-03-25 株式会社 資生堂 水中油型乳化皮膚化粧料
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JP6419087B2 (ja) 2013-01-29 2018-11-07 アプティニックス インコーポレイテッド スピロラクタム系nmda受容体モジュレーターおよびその使用
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WO2017201285A1 (en) 2016-05-19 2017-11-23 Aptinyx Inc. Spiro-lactam nmda receptor modulators and uses thereof
KR102128675B1 (ko) 2016-05-19 2020-06-30 앱티닉스 인크. 스피로-락탐 nmda 수용체 조정제 및 그의 용도
KR102503590B1 (ko) 2016-08-01 2023-02-24 앱티닉스 인크. 스피로-락탐 nmda 수용체 조정제 및 그의 용도
SG11201900551WA (en) 2016-08-01 2019-02-27 Aptinyx Inc Spiro-lactam nmda receptor modulators and uses thereof
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Also Published As

Publication number Publication date
NO901198L (no) 1990-09-17
KR900013961A (ko) 1990-10-22
ES2055197T3 (es) 1994-08-16
AU5073490A (en) 1990-09-20
NZ232809A (en) 1992-05-26
CA2010635C (en) 2001-03-06
US5061721A (en) 1991-10-29
JPH03148221A (ja) 1991-06-25
GR3008225T3 (cg-RX-API-DMAC7.html) 1993-09-30
IE64130B1 (en) 1995-07-12
IL93562A0 (en) 1990-11-29
DE69001503D1 (de) 1993-06-09
JP2963720B2 (ja) 1999-10-18
FI901289A0 (fi) 1990-03-15
EP0387867A1 (en) 1990-09-19
AU624917B2 (en) 1992-06-25
NO901198D0 (no) 1990-03-14
IL93562A (en) 1996-01-31
PT93424A (pt) 1990-11-07
DK0387867T3 (da) 1993-06-01
IE900921L (en) 1990-09-15
DE69001503T2 (de) 1993-09-09
EP0387867B1 (en) 1993-05-05
FI901289A7 (fi) 1990-09-16
PT93424B (pt) 1996-08-30
CA2010635A1 (en) 1990-09-15

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