DE3876817D1 - Anwendung des humanblut-koagulationsfaktors-xiii zur behandlung von colitis gravis. - Google Patents

Anwendung des humanblut-koagulationsfaktors-xiii zur behandlung von colitis gravis.

Info

Publication number
DE3876817D1
DE3876817D1 DE8888101669T DE3876817T DE3876817D1 DE 3876817 D1 DE3876817 D1 DE 3876817D1 DE 8888101669 T DE8888101669 T DE 8888101669T DE 3876817 T DE3876817 T DE 3876817T DE 3876817 D1 DE3876817 D1 DE 3876817D1
Authority
DE
Germany
Prior art keywords
treatment
factor xiii
blood coagulation
human blood
coagulation factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE8888101669T
Other languages
English (en)
Other versions
DE3876817T2 (de
Inventor
Mikio Urabe
Satoshi Tanaka
Kenichiro Tsumura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis KK
Original Assignee
Hoechst Japan Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12192122&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3876817(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoechst Japan Ltd filed Critical Hoechst Japan Ltd
Application granted granted Critical
Publication of DE3876817D1 publication Critical patent/DE3876817D1/de
Publication of DE3876817T2 publication Critical patent/DE3876817T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
DE8888101669T 1987-02-09 1988-02-05 Anwendung des humanblut-koagulationsfaktors-xiii zur behandlung von colitis gravis. Revoked DE3876817T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62026387A JPS63196520A (ja) 1987-02-09 1987-02-09 潰瘍性大腸炎治療剤

Publications (2)

Publication Number Publication Date
DE3876817D1 true DE3876817D1 (de) 1993-02-04
DE3876817T2 DE3876817T2 (de) 1993-05-19

Family

ID=12192122

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888101669T Revoked DE3876817T2 (de) 1987-02-09 1988-02-05 Anwendung des humanblut-koagulationsfaktors-xiii zur behandlung von colitis gravis.

Country Status (16)

Country Link
US (1) US5378687A (de)
EP (1) EP0278416B1 (de)
JP (1) JPS63196520A (de)
KR (1) KR960014789B1 (de)
AT (1) ATE83665T1 (de)
AU (1) AU615428B2 (de)
CA (1) CA1322161C (de)
DE (1) DE3876817T2 (de)
DK (1) DK63488A (de)
ES (1) ES2052614T3 (de)
GR (1) GR3007331T3 (de)
HU (1) HU200277B (de)
IE (1) IE61713B1 (de)
IL (1) IL85346A (de)
PT (1) PT86721B (de)
ZA (1) ZA88852B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3829524A1 (de) * 1988-08-31 1990-03-01 Behringwerke Ag Verwendung von transglutaminasen als immunsuppressiva
US5612456A (en) * 1988-11-14 1997-03-18 Zymogenetics, Inc. Factor XIII compositions
JPH03240738A (ja) * 1990-02-20 1991-10-28 Hoechst Japan Ltd 糖尿病性壊疽治療剤
ATE171071T1 (de) * 1991-12-31 1998-10-15 Zymogenetics Inc Verfahren und zusammensetzungen zur verminderung von blutverlust
EP0726956A1 (de) * 1991-12-31 1996-08-21 Zymogenetics, Inc. Neuartige humane transglutaminasen
ES2303561T3 (es) * 2001-10-09 2008-08-16 Zymogenetics, Inc. Metodo para inhibir la formacion de seromas utilizando el factor xiii.
US20060104946A1 (en) * 2002-08-23 2006-05-18 Zymogenetics, Inc. Method for treating inflammatory bowel disease
WO2006056575A1 (en) 2004-11-23 2006-06-01 Zymogenetics, Inc. Purification of recombinant human factor xiii
US20140286927A1 (en) * 2012-06-19 2014-09-25 Peter Edward Smith Method for the treatment of ulcerative colitis in patients refractory to steroid therapy using leached ligand fibrin stabilizing composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6029687B2 (ja) * 1978-11-07 1985-07-12 株式会社ミドリ十字 ヒト胎盤由来血液凝固第１０３因子の濃縮液の製造方法

Also Published As

Publication number Publication date
HU200277B (en) 1990-05-28
JPH0437049B2 (de) 1992-06-18
DE3876817T2 (de) 1993-05-19
GR3007331T3 (de) 1993-07-30
IE61713B1 (en) 1994-11-30
HUT47221A (en) 1989-02-28
AU615428B2 (en) 1991-10-03
DK63488D0 (da) 1988-02-08
AU1138288A (en) 1988-08-11
US5378687A (en) 1995-01-03
PT86721A (pt) 1988-03-01
ATE83665T1 (de) 1993-01-15
IL85346A0 (en) 1988-07-31
DK63488A (da) 1988-08-10
JPS63196520A (ja) 1988-08-15
CA1322161C (en) 1993-09-14
EP0278416A3 (en) 1990-07-11
KR880009661A (ko) 1988-10-04
EP0278416B1 (de) 1992-12-23
IL85346A (en) 1992-07-15
ES2052614T3 (es) 1994-07-16
IE880334L (en) 1988-08-09
EP0278416A2 (de) 1988-08-17
ZA88852B (en) 1988-11-30
KR960014789B1 (en) 1996-10-19
PT86721B (pt) 1992-05-29

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation