ES2052614T3 - Uso de factor xiii de coagulacion de la sangre humana para el tratamiento de la colitis ulcerosa. - Google Patents

Uso de factor xiii de coagulacion de la sangre humana para el tratamiento de la colitis ulcerosa.

Info

Publication number
ES2052614T3
ES2052614T3 ES88101669T ES88101669T ES2052614T3 ES 2052614 T3 ES2052614 T3 ES 2052614T3 ES 88101669 T ES88101669 T ES 88101669T ES 88101669 T ES88101669 T ES 88101669T ES 2052614 T3 ES2052614 T3 ES 2052614T3
Authority
ES
Spain
Prior art keywords
treatment
factor xiii
human blood
coagulation
ulcerous colitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88101669T
Other languages
English (en)
Inventor
Mikio Urabe
Satoshi Tanaka
Kenichiro Tsumura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis KK
Original Assignee
Hoechst Japan Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12192122&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2052614(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoechst Japan Ltd filed Critical Hoechst Japan Ltd
Application granted granted Critical
Publication of ES2052614T3 publication Critical patent/ES2052614T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)

Abstract

SE DEMUESTRA, MEDIANTE CUATRO CASOS REPRESENTATIVOS, EL EMPLEO DEL FACTOR XIII DE COAGULACION DE LA SANGRE HUMANA PARA EL TRATAMIENTO DE LA COLITIS ULCEROSA. EL TRATAMIENTO CON EL FACTOR XIII CONDUCE A LA DESAPARICION RAPIDA Y TOTAL DE LOS PRINCIPALES SINTOMAS LA QUE MUESTRA LA ENTRADA EN REMISION DE LA ENFERMEDAD.
ES88101669T 1987-02-09 1988-02-05 Uso de factor xiii de coagulacion de la sangre humana para el tratamiento de la colitis ulcerosa. Expired - Lifetime ES2052614T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62026387A JPS63196520A (ja) 1987-02-09 1987-02-09 潰瘍性大腸炎治療剤

Publications (1)

Publication Number Publication Date
ES2052614T3 true ES2052614T3 (es) 1994-07-16

Family

ID=12192122

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88101669T Expired - Lifetime ES2052614T3 (es) 1987-02-09 1988-02-05 Uso de factor xiii de coagulacion de la sangre humana para el tratamiento de la colitis ulcerosa.

Country Status (16)

Country Link
US (1) US5378687A (es)
EP (1) EP0278416B1 (es)
JP (1) JPS63196520A (es)
KR (1) KR960014789B1 (es)
AT (1) ATE83665T1 (es)
AU (1) AU615428B2 (es)
CA (1) CA1322161C (es)
DE (1) DE3876817T2 (es)
DK (1) DK63488A (es)
ES (1) ES2052614T3 (es)
GR (1) GR3007331T3 (es)
HU (1) HU200277B (es)
IE (1) IE61713B1 (es)
IL (1) IL85346A (es)
PT (1) PT86721B (es)
ZA (1) ZA88852B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3829524A1 (de) * 1988-08-31 1990-03-01 Behringwerke Ag Verwendung von transglutaminasen als immunsuppressiva
US5612456A (en) * 1988-11-14 1997-03-18 Zymogenetics, Inc. Factor XIII compositions
JPH03240738A (ja) * 1990-02-20 1991-10-28 Hoechst Japan Ltd 糖尿病性壊疽治療剤
AU3423493A (en) * 1991-12-31 1993-07-28 Zymogenetics Inc. Methods and compositions for reducing blood loss
US5514579A (en) * 1991-12-31 1996-05-07 Zymogenetics, Inc. Human transglutaminases
AU2002360269B2 (en) 2001-10-09 2007-03-22 Zymogenetics, Inc. Method for inhibiting the formation of seromas using factor XIII
AU2003273243A1 (en) * 2002-08-23 2004-03-11 Zymogenetics, Inc. Method for treating inflammatory bowel disease
EP1817339B1 (en) 2004-11-23 2012-01-11 ZymoGenetics, Inc. Purification of recombinant human factor xiii
US20140286927A1 (en) * 2012-06-19 2014-09-25 Peter Edward Smith Method for the treatment of ulcerative colitis in patients refractory to steroid therapy using leached ligand fibrin stabilizing composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6029687B2 (ja) * 1978-11-07 1985-07-12 株式会社ミドリ十字 ヒト胎盤由来血液凝固第１０３因子の濃縮液の製造方法

Also Published As

Publication number Publication date
EP0278416A2 (en) 1988-08-17
DE3876817D1 (de) 1993-02-04
PT86721B (pt) 1992-05-29
EP0278416A3 (en) 1990-07-11
DK63488A (da) 1988-08-10
GR3007331T3 (es) 1993-07-30
IL85346A (en) 1992-07-15
IE61713B1 (en) 1994-11-30
ZA88852B (en) 1988-11-30
AU615428B2 (en) 1991-10-03
JPS63196520A (ja) 1988-08-15
IE880334L (en) 1988-08-09
PT86721A (pt) 1988-03-01
HU200277B (en) 1990-05-28
JPH0437049B2 (es) 1992-06-18
EP0278416B1 (en) 1992-12-23
IL85346A0 (en) 1988-07-31
CA1322161C (en) 1993-09-14
US5378687A (en) 1995-01-03
DK63488D0 (da) 1988-02-08
KR960014789B1 (en) 1996-10-19
DE3876817T2 (de) 1993-05-19
KR880009661A (ko) 1988-10-04
ATE83665T1 (de) 1993-01-15
AU1138288A (en) 1988-08-11
HUT47221A (en) 1989-02-28

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