ATE88753T1 - Acylaminosaeure-racemase, herstellung und verwendung. - Google Patents

Acylaminosaeure-racemase, herstellung und verwendung.

Info

Publication number
ATE88753T1
ATE88753T1 AT88113315T AT88113315T ATE88753T1 AT E88753 T1 ATE88753 T1 AT E88753T1 AT 88113315 T AT88113315 T AT 88113315T AT 88113315 T AT88113315 T AT 88113315T AT E88753 T1 ATE88753 T1 AT E88753T1
Authority
AT
Austria
Prior art keywords
racemase
alpha
optically active
acid
acylaminosacid
Prior art date
Application number
AT88113315T
Other languages
English (en)
Inventor
Takeshi Takahashi
Kazunori Hatano
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE88753T1 publication Critical patent/ATE88753T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3153—Streptokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Adornments (AREA)
AT88113315T 1987-08-21 1988-08-17 Acylaminosaeure-racemase, herstellung und verwendung. ATE88753T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20848487 1987-08-21
EP88113315A EP0304021B1 (de) 1987-08-21 1988-08-17 Acylaminosäure-Racemase, Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ATE88753T1 true ATE88753T1 (de) 1993-05-15

Family

ID=16556926

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88113315T ATE88753T1 (de) 1987-08-21 1988-08-17 Acylaminosaeure-racemase, herstellung und verwendung.

Country Status (8)

Country Link
US (1) US4981799A (de)
EP (1) EP0304021B1 (de)
KR (1) KR970000185B1 (de)
CN (1) CN1034183C (de)
AT (1) ATE88753T1 (de)
DE (1) DE3880585T2 (de)
DK (1) DK462488A (de)
HU (1) HU204558B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0414914B1 (de) * 1989-02-28 1994-05-11 Suntory Limited Trehalostatin und seine herstellung
US5525501A (en) * 1990-09-14 1996-06-11 Takeda Chemical Industries, Ltd. DNA Fragment encoding acylamino acid racemase
CA2038202A1 (en) * 1990-09-14 1992-03-15 Masaharu Tokuyama Dna and use thereof
DE69124459T3 (de) * 1990-11-02 2001-05-31 Novartis Ag, Basel Zyklosporine
US5206162A (en) * 1991-10-17 1993-04-27 National Science Council Of Republic Of China Process for making D-aminoacylase
US5194383A (en) * 1991-11-21 1993-03-16 National Science Council Of Republic Of China Process for making L-aminoacylase
US5252216A (en) * 1992-03-24 1993-10-12 Smithkline Beecham Corporation Protein purification
JP3333969B2 (ja) * 1992-10-08 2002-10-15 株式会社林原生物化学研究所 Ｄ−ケトヘキソース・３−エピメラーゼとその製造方法並びに用途
PT868526E (pt) * 1995-12-20 2002-12-31 Aventis Pharma Inc Processo para a preparacao de n-acetil-(l)-4-cianofenilalanina ac-(l)-phe(4-cn)-oh e n-acetil-(l)-p-amidinofenilalanina-ciclo-hexilglicina-beta-(3-n-metilpiridinio)-alanina ac-(l)-paph-chg-palme(3)-nh2
CN1062604C (zh) * 1998-04-27 2001-02-28 湖北省八峰药化股份有限公司 氨基酰化水解酶拆分混旋蛋氨酸制左旋蛋氨酸的方法
EP1121446A1 (de) * 1998-10-20 2001-08-08 Chirotech Technology Limited Aminoacylase und seiner verwendung zur herstellung von d-aminosäuren
DE19935268A1 (de) 1999-07-27 2001-02-08 Degussa N-Acetylaminosäureracemase
US6664083B2 (en) 2000-03-01 2003-12-16 Daichel Chemical Industries, Ltd. Methods for racemizing N-acylamino acids and producing optically active amino acids
DE10050123A1 (de) * 2000-10-11 2002-04-25 Degussa Verfahren zur Herstellung von Aminosäuren
DE10050124A1 (de) * 2000-10-11 2002-04-25 Degussa Verwendung der Acetylaminosäureracemase aus Amycolatopsis orientalis Racemisierung von Carbamoylaminosäuren
CN101200513A (zh) 2006-12-12 2008-06-18 中国石油天然气股份有限公司 一种柔性聚合物颗粒及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1417060A (en) * 1972-10-19 1975-12-10 Ajinomoto Kk Racemization of optically active n-acyl amino acids
DE3435095C2 (de) * 1984-09-25 1986-07-24 Degussa Ag, 6000 Frankfurt Verfahren zur Racemisierung von N-Acetyl-D(L)-α-aminocarbonsäuren
JPS6255097A (ja) * 1985-09-04 1987-03-10 Nitto Chem Ind Co Ltd Ｌ−アミノ酸の製造法
DE3712539A1 (de) * 1986-07-24 1988-02-11 Ruetgerswerke Ag Verfahren zur mikrobiellen herstellung von l-alpha-aminosaeuren

Also Published As

Publication number Publication date
KR890003948A (ko) 1989-04-19
HU204558B (en) 1992-01-28
US4981799A (en) 1991-01-01
DK462488A (da) 1989-02-22
CN1035320A (zh) 1989-09-06
KR970000185B1 (ko) 1997-01-06
CN1034183C (zh) 1997-03-05
EP0304021A3 (en) 1990-06-20
EP0304021A2 (de) 1989-02-22
EP0304021B1 (de) 1993-04-28
DK462488D0 (da) 1988-08-18
DE3880585D1 (de) 1993-06-03
DE3880585T2 (de) 1993-08-12
HUT47317A (en) 1989-02-28

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