ATE109796T1 - Gewebeinhibitor für metalloproteasen (timp-2). - Google Patents
Gewebeinhibitor für metalloproteasen (timp-2).Info
- Publication number
- ATE109796T1 ATE109796T1 AT90870075T AT90870075T ATE109796T1 AT E109796 T1 ATE109796 T1 AT E109796T1 AT 90870075 T AT90870075 T AT 90870075T AT 90870075 T AT90870075 T AT 90870075T AT E109796 T1 ATE109796 T1 AT E109796T1
- Authority
- AT
- Austria
- Prior art keywords
- follows
- tissue inhibitor
- collagenase
- amino acid
- timp
- Prior art date
Links
- 102000005741 Metalloproteases Human genes 0.000 title abstract 2
- 108010006035 Metalloproteases Proteins 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 102000005354 Tissue Inhibitor of Metalloproteinase-2 Human genes 0.000 title 1
- 108010031372 Tissue Inhibitor of Metalloproteinase-2 Proteins 0.000 title 1
- 102000029816 Collagenase Human genes 0.000 abstract 2
- 108060005980 Collagenase Proteins 0.000 abstract 2
- 229960002424 collagenase Drugs 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000029087 digestion Effects 0.000 abstract 1
- 229940088598 enzyme Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35804389A | 1989-05-26 | 1989-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE109796T1 true ATE109796T1 (de) | 1994-08-15 |
Family
ID=23408062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90870075T ATE109796T1 (de) | 1989-05-26 | 1990-05-21 | Gewebeinhibitor für metalloproteasen (timp-2). |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0404750B1 (de) |
| AT (1) | ATE109796T1 (de) |
| DE (1) | DE69011433T2 (de) |
| DK (1) | DK0404750T3 (de) |
| ES (1) | ES2060134T3 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0464147B1 (de) * | 1989-03-21 | 2002-06-26 | THE UNITED STATES OF AMERICA as represented by the Secretary UNITED STATES DEPARTMENT OF COMMERCE | Matrizenmetalloproteinase-inhibitor-peptide |
| JP2877509B2 (ja) * | 1989-05-19 | 1999-03-31 | アムジエン・インコーポレーテツド | メタロプロテイナーゼ阻害剤 |
| US5714465A (en) | 1989-05-19 | 1998-02-03 | Amgen Inc. | Method of inhibiting tumor cell dissemination with a metalloproteinase inhibitor |
| US6022948A (en) * | 1996-09-17 | 2000-02-08 | Washington University | Method of cell surface activation and inhibition |
| NZ500656A (en) * | 1997-05-12 | 2001-11-30 | Tno | Vector containing a nucleic acid insertion expressing a hybrid polypeptide with a protease inhibitor domain and a receptor binding domain |
| WO2001042438A2 (en) * | 1999-12-13 | 2001-06-14 | Regents Of The University Of Minnesota | Leukolysin/mmp25/mt6-mmp |
| US7247704B2 (en) | 2000-12-18 | 2007-07-24 | Arriva Pharmaceuticals, Inc. | Multifunctional protease inhibitors and their use in treatment of disease |
| KR101363455B1 (ko) * | 2011-09-09 | 2014-02-21 | (주)케어젠 | 매트릭스 메탈로프로테아제 활성 억제 펩타이드 및 이의 용도 |
-
1990
- 1990-05-21 DE DE69011433T patent/DE69011433T2/de not_active Expired - Fee Related
- 1990-05-21 ES ES90870075T patent/ES2060134T3/es not_active Expired - Lifetime
- 1990-05-21 EP EP90870075A patent/EP0404750B1/de not_active Expired - Lifetime
- 1990-05-21 DK DK90870075.0T patent/DK0404750T3/da active
- 1990-05-21 AT AT90870075T patent/ATE109796T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2060134T3 (es) | 1994-11-16 |
| DK0404750T3 (da) | 1994-10-03 |
| EP0404750B1 (de) | 1994-08-10 |
| EP0404750A1 (de) | 1990-12-27 |
| DE69011433T2 (de) | 1995-04-06 |
| DE69011433D1 (de) | 1994-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |