DK447587A - Oxolabdaner, deres fremstilling og anvendelse - Google Patents

Oxolabdaner, deres fremstilling og anvendelse

Info

Publication number
DK447587A
DK447587A DK447587A DK447587A DK447587A DK 447587 A DK447587 A DK 447587A DK 447587 A DK447587 A DK 447587A DK 447587 A DK447587 A DK 447587A DK 447587 A DK447587 A DK 447587A
Authority
DK
Denmark
Prior art keywords
oxolabdanes
manufacturing
medicaments
therefor
compounds
Prior art date
Application number
DK447587A
Other languages
English (en)
Other versions
DK447587D0 (da
Inventor
Nicholas Joseph Hrib
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of DK447587D0 publication Critical patent/DK447587D0/da
Publication of DK447587A publication Critical patent/DK447587A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pyrane Compounds (AREA)
DK447587A 1986-08-28 1987-08-27 Oxolabdaner, deres fremstilling og anvendelse DK447587A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/901,337 US4740522A (en) 1986-08-28 1986-08-28 Oxolabdanes useful as pharmaceuticals for reducing intraocular pressure

Publications (2)

Publication Number Publication Date
DK447587D0 DK447587D0 (da) 1987-08-27
DK447587A true DK447587A (da) 1988-02-29

Family

ID=25413969

Family Applications (1)

Application Number Title Priority Date Filing Date
DK447587A DK447587A (da) 1986-08-28 1987-08-27 Oxolabdaner, deres fremstilling og anvendelse

Country Status (9)

Country Link
US (3) US4740522A (da)
EP (1) EP0257631B1 (da)
JP (1) JPS6388175A (da)
AT (1) ATE69223T1 (da)
DE (1) DE3774367D1 (da)
DK (1) DK447587A (da)
ES (1) ES2039386T3 (da)
GR (1) GR3003638T3 (da)
PT (1) PT85602B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130332A (en) * 1986-08-28 1992-07-14 Hoechst Roussel Pharmaceuticals Inc. Oxolabdanes
US4978678A (en) * 1986-11-20 1990-12-18 Hoechst-Roussel Pharmaceuticals Inc. 12-halogenated forskolin derivatives
US5177207A (en) * 1989-01-11 1993-01-05 Hoechst-Roussel Pharmaceuticals, Inc. 7-aryl and heteroaryl ethers of desacetylforskolin
US4999351A (en) * 1989-01-11 1991-03-12 Hoechst-Roussel Pharmaceuticals, Inc. 7-aryl and heteroaryl ethers of desacetylforskolin

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557784C2 (de) * 1975-12-22 1986-04-17 Hoechst Ag, 6230 Frankfurt Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate
DE2654796A1 (de) * 1976-12-03 1978-06-08 Hoechst Ag Polyoxygenierte labdan-derivate
US4517200A (en) * 1982-12-27 1985-05-14 Schering-Plough Corporation Method for treating allergic reactions with forskolin
US4564626A (en) * 1983-04-01 1986-01-14 Schering Corporation Methods of inducing bronchodilation
US4476140A (en) * 1983-05-16 1984-10-09 Yale University Composition and method for treatment of glaucoma
WO1985003637A1 (en) * 1984-02-24 1985-08-29 Halprin Kenneth M Methods and pharmaceutical compositions for the treatment of hyperplastic diseases of the skin
DE3407514A1 (de) * 1984-03-01 1985-09-26 Hoechst Ag, 6230 Frankfurt Verwendung von polyoxygenierten labdanderivaten zur behandlung von konstriktionen der atemwege
DE3502685A1 (de) * 1985-01-26 1986-09-04 Hoechst Ag, 6230 Frankfurt Forskolin, seine analoge und derivate, verfahren zu deren herstellung mittels mikrobieller umwandlungen und die anwendung dieser verbindungen als arzneimittel
US4639446A (en) * 1984-12-14 1987-01-27 Hoechst-Roussel Pharmaceuticals Inc. Aminoacyllabdanes, pharmaceutical compositions and use
DE3581725D1 (de) * 1984-12-14 1991-03-14 Hoechst Roussel Pharma Aminoacyllabdane, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE62683T1 (de) * 1985-03-01 1991-05-15 Hoechst Roussel Pharma Labdanderivate, verfahren zu deren herstellung und deren verwendung als arzneimittel.
US4851397A (en) * 1985-03-01 1989-07-25 Hoechst-Roussel Pharmaceuticals Inc. Labdanes, pharmaceutical compositions, and their use
US4677103A (en) * 1985-03-01 1987-06-30 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
DE3527336A1 (de) * 1985-07-31 1987-02-05 Hoechst Ag Verfahren zur mikrobiellen hydroxylierung von forskolin und seinen derivaten durch neurospora crassa
IN166900B (da) * 1987-06-03 1990-08-04 Hoechst India
DE3730748A1 (de) * 1987-06-06 1988-12-22 Hoechst Ag Neue polyoxygenierte labdanderivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
EP0257631A2 (en) 1988-03-02
DK447587D0 (da) 1987-08-27
DE3774367D1 (de) 1991-12-12
US4883885A (en) 1989-11-28
US4933476A (en) 1990-06-12
PT85602A (en) 1987-09-01
PT85602B (pt) 1990-05-31
JPS6388175A (ja) 1988-04-19
EP0257631B1 (en) 1991-11-06
ES2039386T3 (es) 1993-10-01
ATE69223T1 (de) 1991-11-15
US4740522A (en) 1988-04-26
GR3003638T3 (da) 1993-03-16
EP0257631A3 (en) 1988-08-17

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