ATE82961T1 - Indochinon-verbindungen. - Google Patents

Indochinon-verbindungen.

Info

Publication number
ATE82961T1
ATE82961T1 AT87902608T AT87902608T ATE82961T1 AT E82961 T1 ATE82961 T1 AT E82961T1 AT 87902608 T AT87902608 T AT 87902608T AT 87902608 T AT87902608 T AT 87902608T AT E82961 T1 ATE82961 T1 AT E82961T1
Authority
AT
Austria
Prior art keywords
group
substituted
hydrogen
alkyl group
alkyl
Prior art date
Application number
AT87902608T
Other languages
English (en)
Inventor
Willem Nico Speckamp
Everardus Arnoldus Oostveen
Original Assignee
Willem Nico Speckamp
Everardus Arnoldus Oostveen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868609369A external-priority patent/GB8609369D0/en
Priority claimed from GB868615383A external-priority patent/GB8615383D0/en
Priority claimed from GB868629049A external-priority patent/GB8629049D0/en
Application filed by Willem Nico Speckamp, Everardus Arnoldus Oostveen filed Critical Willem Nico Speckamp
Application granted granted Critical
Publication of ATE82961T1 publication Critical patent/ATE82961T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
AT87902608T 1986-04-17 1987-04-15 Indochinon-verbindungen. ATE82961T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB868609369A GB8609369D0 (en) 1986-04-17 1986-04-17 Indoloquinone compounds
GB868615383A GB8615383D0 (en) 1986-06-24 1986-06-24 Pathways to bioactive indoletype compounds
GB868629049A GB8629049D0 (en) 1986-12-04 1986-12-04 Indoloquinone compounds
EP87902608A EP0302874B1 (de) 1986-04-17 1987-04-15 Indochinon-verbindungen
PCT/GB1987/000253 WO1987006227A2 (en) 1986-04-17 1987-04-15 Indoloquinone compounds

Publications (1)

Publication Number Publication Date
ATE82961T1 true ATE82961T1 (de) 1992-12-15

Family

ID=27262993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87902608T ATE82961T1 (de) 1986-04-17 1987-04-15 Indochinon-verbindungen.

Country Status (8)

Country Link
US (1) US5079257A (de)
EP (1) EP0302874B1 (de)
JP (1) JPH0819095B2 (de)
AT (1) ATE82961T1 (de)
AU (1) AU615877B2 (de)
DE (1) DE3782938T2 (de)
DK (1) DK171079B1 (de)
WO (1) WO1987006227A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH678726A5 (de) * 1989-01-12 1991-10-31 Vni Khim Farmatsevtichesky I I
JPH0616628A (ja) * 1992-04-07 1994-01-25 Kyowa Hakko Kogyo Co Ltd インドール誘導体
AU1166097A (en) * 1995-12-21 1997-07-17 British Technology Group Limited Indoloquinone derivatives as bioreductive agents
EP1864660B1 (de) * 2001-11-01 2010-12-29 Spectrum Pharmaceuticals, Inc. Medizinische Zusammensetzungen zur intravesikalen Behandlung von Blasenkrebs
US8563592B2 (en) 2001-11-01 2013-10-22 Spectrum Pharmaceuticals, Inc. Bladder cancer treatment and methods
CA2516078C (en) * 2003-02-28 2014-04-29 Oxigene, Inc. Catechol compositions and use thereof
AU2006230582A1 (en) * 2005-03-31 2006-10-05 Spectrum Pharmaceuticals, Inc. Indoloquinone tumor radiation sensitization
WO2014062856A1 (en) 2012-10-16 2014-04-24 Halozyme, Inc. Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3206471A (en) * 1963-10-11 1965-09-14 American Cyanamid Co Novel substituted 3-(alpha-alkoxycarbonyloxy-lower alkyl)-and 3-(alpha-phenoxycarbonyloxy-lower alkyl)-4, 7-indoloquinones and novel methods of preparing the same
US3265698A (en) * 1964-08-07 1966-08-09 American Cyanamid Co Novel substituted 3-(alpha-carbamoyloxy-lower alkyl)-4, 7-indoloquinones

Also Published As

Publication number Publication date
AU615877B2 (en) 1991-10-17
DK659887A (da) 1988-02-15
WO1987006227A2 (en) 1987-10-22
DE3782938T2 (de) 1993-10-21
US5079257A (en) 1992-01-07
AU7236187A (en) 1987-11-09
DK171079B1 (da) 1996-05-28
JPH01502906A (ja) 1989-10-05
EP0302874B1 (de) 1992-12-02
EP0302874A1 (de) 1989-02-15
DK659887D0 (da) 1987-12-16
JPH0819095B2 (ja) 1996-02-28
WO1987006227A3 (en) 1988-01-28
DE3782938D1 (de) 1993-01-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee