ATE82283T1 - Herstellung von 2-(2-pyridylmethylsulfinyl)benzimidazol-verbindungen. - Google Patents

Herstellung von 2-(2-pyridylmethylsulfinyl)benzimidazol-verbindungen.

Info

Publication number
ATE82283T1
ATE82283T1 AT88307191T AT88307191T ATE82283T1 AT E82283 T1 ATE82283 T1 AT E82283T1 AT 88307191 T AT88307191 T AT 88307191T AT 88307191 T AT88307191 T AT 88307191T AT E82283 T1 ATE82283 T1 AT E82283T1
Authority
AT
Austria
Prior art keywords
pyridylmethylsulfinyl
benzimidazole compounds
preparation
compounds
benzimidazole
Prior art date
Application number
AT88307191T
Other languages
English (en)
Inventor
Masayasu Kato
Yoshio Toyoshima
Norio Iwano
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16330618&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE82283(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE82283T1 publication Critical patent/ATE82283T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT88307191T 1987-08-04 1988-08-03 Herstellung von 2-(2-pyridylmethylsulfinyl)benzimidazol-verbindungen. ATE82283T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19480987 1987-08-04
EP88307191A EP0302720B1 (de) 1987-08-04 1988-08-03 Herstellung von 2-(2-Pyridylmethylsulfinyl)-benzimidazol-Verbindungen

Publications (1)

Publication Number Publication Date
ATE82283T1 true ATE82283T1 (de) 1992-11-15

Family

ID=16330618

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88307191T ATE82283T1 (de) 1987-08-04 1988-08-03 Herstellung von 2-(2-pyridylmethylsulfinyl)benzimidazol-verbindungen.

Country Status (11)

Country Link
US (1) US5578732A (de)
EP (1) EP0302720B1 (de)
KR (1) KR960000047B1 (de)
AT (1) ATE82283T1 (de)
CA (1) CA1263119A (de)
DE (1) DE3875848T2 (de)
DK (1) DK171989B1 (de)
ES (1) ES2052728T3 (de)
GR (1) GR3006974T3 (de)
HU (1) HU199828B (de)
IE (1) IE61717B1 (de)

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* Cited by examiner, † Cited by third party
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US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
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US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
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KR100430575B1 (ko) * 2001-02-21 2004-05-10 주식회사 씨트리 란소프라졸 및 그 중간체의 제조방법
KR100783020B1 (ko) * 2001-03-23 2007-12-07 동아제약주식회사 2-메틸클로라이드 피리딘 유도체 및 이를 이용한 벤즈이미다졸 유도체의 제조 방법
EP1437352A4 (de) * 2001-09-25 2004-12-08 Takeda Chemical Industries Ltd Benzimidazolverbindung, verfahren zu deren herstellung und deren verwendung
CN1681802A (zh) * 2002-03-27 2005-10-12 特瓦制药工业有限公司 兰索拉唑多晶型和其制备方法
KR100873419B1 (ko) * 2002-06-18 2008-12-11 페어차일드코리아반도체 주식회사 높은 항복 전압, 낮은 온 저항 및 작은 스위칭 손실을갖는 전력용 반도체 소자
WO2004011455A1 (en) * 2002-07-26 2004-02-05 Teva Pharmaceutical Industries Ltd. Preparation of lansoprazole and related compounds
EP1837335A1 (de) * 2002-08-21 2007-09-26 Teva Pharmaceutical Industries Ltd Verfahren zur Reinigung von Lansoprazol
DE60316791T2 (de) * 2002-08-21 2008-07-24 Teva Pharmaceutical Industries Ltd. Verfahren zur aufreinigung von lanzoprazol
AU2003273000A1 (en) * 2002-10-16 2004-05-04 Takeda Pharmaceutical Company Limited Stable solid preparations
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JP2006516574A (ja) * 2003-02-05 2006-07-06 テバ ファーマシューティカル インダストリーズ リミティド ランソプラゾール安定化方法
FR2852956B1 (fr) * 2003-03-28 2006-08-04 Negma Gild Procede de preparation enantioselective de derives de sulfoxydes
CA2520157A1 (fr) * 2003-03-28 2004-10-14 Sidem Pharma Procede de preparation enantioselective de derives de sulfoxydes
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KR100758600B1 (ko) * 2006-01-05 2007-09-13 주식회사 대웅제약 란소프라졸 결정형 ａ의 제조방법
US8129536B2 (en) * 2006-09-22 2012-03-06 Orchid Chemicals & Pharmaceuticals Limited Method for the purification of lansoprazole
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WO2009066309A2 (en) * 2007-07-12 2009-05-28 Cadila Healthcare Limited Process for preparation of omeprazole
EP2203068A4 (de) 2007-10-12 2012-08-22 Takeda Pharmaceuticals Usa Inc Verfahren zur behandlung von magen-darm-erkrankungen unabhängig von der nahrungsaufnahme
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ES2343935B1 (es) * 2008-12-29 2011-04-28 Laboratorios Viñas S.A. Intermedios utiles para la obtencion de 2-(2-piridinilmetilsulfinil)-1h-benzimidazoles y procedimientos correspondientes.
KR20100101405A (ko) * 2009-03-09 2010-09-17 한미홀딩스 주식회사 비결정형의 (+)-란소프라졸 제조방법 및 이에 사용되는 (+)-란소프라졸 알코올레이트
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CN102180865B (zh) * 2011-03-17 2013-01-16 浙江工业大学 一种兰索拉唑的合成方法
US9119769B2 (en) 2011-12-30 2015-09-01 The Curators Of The University Of Missouri Method for transforming pharmaceutical crystal forms
WO2013108068A1 (en) 2012-01-21 2013-07-25 Jubilant Life Sciences Limited Process for the preparation of 2-pyridinylmethylsulfinyl benzimidazoles, their analogs and optically active enantiomers
CN103724325B (zh) * 2013-12-10 2016-04-13 南京工业大学 制备亚磺酰基-1-氢-苯并咪唑衍生物的方法
CN104019635B (zh) * 2014-06-19 2015-05-27 上海慈瑞医药科技有限公司 一种兰索拉唑原料药化合物及其干燥工艺
CN116891458A (zh) * 2023-06-19 2023-10-17 南京唯创远医药科技有限公司 一种艾普拉唑的制备方法

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SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
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JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
DK171989B1 (da) * 1987-08-04 1997-09-08 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler

Also Published As

Publication number Publication date
DK428188D0 (da) 1988-08-01
CA1263119A (en) 1989-11-21
IE61717B1 (en) 1994-11-30
KR890003738A (ko) 1989-04-17
DE3875848T2 (de) 1993-03-25
HU199828B (en) 1990-03-28
GR3006974T3 (de) 1993-06-30
EP0302720A1 (de) 1989-02-08
HUT49346A (en) 1989-09-28
IE882376L (en) 1989-02-04
KR960000047B1 (ko) 1996-01-03
DE3875848D1 (de) 1992-12-17
ES2052728T3 (es) 1994-07-16
US5578732A (en) 1996-11-26
DK171989B1 (da) 1997-09-08
DK428188A (da) 1989-02-05
EP0302720B1 (de) 1992-11-11

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