DK171989B1
(da)
*
|
1987-08-04 |
1997-09-08 |
Takeda Chemical Industries Ltd |
Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler
|
SE8804629D0
(sv)
*
|
1988-12-22 |
1988-12-22 |
Ab Haessle |
New therapeutically active compounds
|
CA2053527C
(en)
|
1990-10-17 |
2002-03-12 |
Takashi Sohda |
Pyridine derivatives, their production and use
|
ES2026761A6
(es)
*
|
1990-10-31 |
1992-05-01 |
Genesis Para La Investigacion |
Procedimiento de obtencion del omeprazol.
|
WO1993006097A1
(en)
*
|
1991-09-20 |
1993-04-01 |
Merck & Co., Inc. |
Novel process for the preparation of anti-ulcer agents
|
EP0649305A1
(de)
*
|
1992-07-08 |
1995-04-26 |
Monsanto Company |
Benzimidazolen zur erleichterung der magengeschwuere bei schweinen
|
ES2060541B1
(es)
*
|
1993-02-26 |
1995-11-16 |
Vinas Lab |
Nuevo procedimiento para la sintesis de un derivado de 2-(2-piridilmetilsufinil) bencimidazol, y nuevos productos intermedios obtenidos con el mismo.
|
ES2063705B1
(es)
*
|
1993-06-14 |
1995-07-16 |
S A L V A T Lab Sa |
Intermedio para la sintesis de lansoprazol y su procedimiento de obtencion.
|
US5374730A
(en)
|
1993-11-04 |
1994-12-20 |
Torcan Chemical Ltd. |
Preparation of omeprazole and lansoprazole
|
TW385306B
(en)
*
|
1996-11-14 |
2000-03-21 |
Takeda Chemical Industries Ltd |
Method for producing crystals of benzimidazole derivatives
|
US6437139B1
(en)
|
1997-05-06 |
2002-08-20 |
Pdi-Research Laboratories, Inc. |
Synthesis of pharmaceutically useful pyridine derivatives
|
CA2204580A1
(en)
*
|
1997-05-06 |
1998-11-06 |
Michel Zoghbi |
Synthesis of pharmaceutically useful pyridine derivatives
|
KR100458170B1
(ko)
*
|
1997-05-26 |
2005-05-03 |
동아제약주식회사 |
2-[3-메톡시-4-(2,2,2-트리플로로에톡시)2-피리딜]메틸설피닐-1h-벤즈이미다졸의신규제조방법
|
US6096340A
(en)
*
|
1997-11-14 |
2000-08-01 |
Andrx Pharmaceuticals, Inc. |
Omeprazole formulation
|
US6174548B1
(en)
|
1998-08-28 |
2001-01-16 |
Andrx Pharmaceuticals, Inc. |
Omeprazole formulation
|
US6303787B1
(en)
*
|
1998-05-27 |
2001-10-16 |
Natco Pharma Limited |
Intermediates and an improved process for the preparation of Omeprazole employing the said intermediates
|
US6191148B1
(en)
|
1998-08-11 |
2001-02-20 |
Merck & Co., Inc. |
Omerazole process and compositions thereof
|
US6166213A
(en)
*
|
1998-08-11 |
2000-12-26 |
Merck & Co., Inc. |
Omeprazole process and compositions thereof
|
US6733778B1
(en)
|
1999-08-27 |
2004-05-11 |
Andrx Pharmaceuticals, Inc. |
Omeprazole formulation
|
TWI275587B
(en)
|
1999-06-17 |
2007-03-11 |
Takeda Chemical Industries Ltd |
A crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
|
PL333847A1
(en)
*
|
1999-06-18 |
2001-01-02 |
Inst Farmaceutyczny |
Crystalline forms of lansoprozole and method of obtaining lansoprazole in pharmacologically advanthageous crystalline form
|
US6555139B2
(en)
|
1999-06-28 |
2003-04-29 |
Wockhardt Europe Limited |
Preparation of micron-size pharmaceutical particles by microfluidization
|
US6608092B1
(en)
*
|
1999-06-30 |
2003-08-19 |
Takeda Chemical Industries, Ltd. |
Crystals of benzimidazole compounds
|
US6245913B1
(en)
|
1999-06-30 |
2001-06-12 |
Wockhardt Europe Limited |
Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
|
US6262086B1
(en)
|
1999-08-26 |
2001-07-17 |
Robert R. Whittle |
Pharmaceutical unit dosage form
|
US6262085B1
(en)
|
1999-08-26 |
2001-07-17 |
Robert R. Whittle |
Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
|
US6326384B1
(en)
|
1999-08-26 |
2001-12-04 |
Robert R. Whittle |
Dry blend pharmaceutical unit dosage form
|
US6268385B1
(en)
|
1999-08-26 |
2001-07-31 |
Robert R. Whittle |
Dry blend pharmaceutical formulations
|
US6316020B1
(en)
|
1999-08-26 |
2001-11-13 |
Robert R. Whittle |
Pharmaceutical formulations
|
US6312712B1
(en)
|
1999-08-26 |
2001-11-06 |
Robert R. Whittle |
Method of improving bioavailability
|
US6312723B1
(en)
|
1999-08-26 |
2001-11-06 |
Robert R. Whittle |
Pharmaceutical unit dosage form
|
US6369087B1
(en)
|
1999-08-26 |
2002-04-09 |
Robert R. Whittle |
Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
|
US6780880B1
(en)
|
1999-08-26 |
2004-08-24 |
Robert R. Whittle |
FT-Raman spectroscopic measurement
|
KR100362947B1
(ko)
*
|
1999-09-21 |
2002-11-30 |
주식회사 대웅 |
설폭시드 화합물의 제조방법
|
DE19951960C2
(de)
*
|
1999-10-28 |
2002-06-27 |
Gruenenthal Gmbh |
Verfahren zur Herstellung als Ulkustherapeutika geeigneter Benzimidazol-Derivate
|
DK1293507T3
(da)
*
|
2000-05-15 |
2007-12-27 |
Takeda Pharmaceutical |
Fremgangsmåde til fremstilling af krystaller
|
AU2002218506A1
(en)
*
|
2000-12-01 |
2002-06-11 |
Takeda Chemical Industries Ltd. |
Process for the crystallization of (r)- or (s)-lansoprazole
|
WO2002062786A1
(en)
|
2001-02-02 |
2002-08-15 |
Teva Pharmaceutical Industries Ltd. |
Processes for the production of substituted 2-(2-pyridylmethyl) sulfinyl-1h-benzimidazoles
|
KR100430575B1
(ko)
*
|
2001-02-21 |
2004-05-10 |
주식회사 씨트리 |
란소프라졸 및 그 중간체의 제조방법
|
KR100783020B1
(ko)
*
|
2001-03-23 |
2007-12-07 |
동아제약주식회사 |
2-메틸클로라이드 피리딘 유도체 및 이를 이용한 벤즈이미다졸 유도체의 제조 방법
|
US20040248941A1
(en)
*
|
2001-09-25 |
2004-12-09 |
Keiji Kamiyama |
Benzimidazone compound, process for producing the same, and use thereof
|
WO2003082857A2
(en)
*
|
2002-03-27 |
2003-10-09 |
Teva Pharmaceutical Industries Ltd. |
Lansoprazole polymorphs and processes for preparation thereof
|
KR100873419B1
(ko)
*
|
2002-06-18 |
2008-12-11 |
페어차일드코리아반도체 주식회사 |
높은 항복 전압, 낮은 온 저항 및 작은 스위칭 손실을갖는 전력용 반도체 소자
|
EP1467987A1
(de)
*
|
2002-07-26 |
2004-10-20 |
Teva Pharmaceutical Industries Ltd. |
Herstellung von lansoprazol und derivaten
|
DE60316791T2
(de)
*
|
2002-08-21 |
2008-07-24 |
Teva Pharmaceutical Industries Ltd. |
Verfahren zur aufreinigung von lanzoprazol
|
EP1837335A1
(de)
*
|
2002-08-21 |
2007-09-26 |
Teva Pharmaceutical Industries Ltd |
Verfahren zur Reinigung von Lansoprazol
|
EP2596791B1
(de)
*
|
2002-10-16 |
2015-04-01 |
Takeda Pharmaceutical Company Limited |
Stabile, feste Präparate
|
EP1465890B1
(de)
*
|
2002-11-18 |
2007-04-04 |
Teva Pharmaceutical Industries Ltd. |
Stabiles lansoprazol, enthaltend mehr als 500 ppm bis zu 3000 ppm wasser und mehr als 200 ppm bis zu 5000 ppm alkohol
|
WO2004056804A2
(en)
|
2002-12-19 |
2004-07-08 |
Teva Pharmaceutical Industries Ltd. |
Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
|
CA2515130A1
(en)
*
|
2003-02-05 |
2004-08-26 |
Teva Pharmaceutical Industries Ltd. |
Method of stabilizing lansoprazole
|
FR2852956B1
(fr)
*
|
2003-03-28 |
2006-08-04 |
Negma Gild |
Procede de preparation enantioselective de derives de sulfoxydes
|
EP1608649A2
(de)
*
|
2003-03-28 |
2005-12-28 |
Sidem Pharma SA |
Verfahren zur herstellung von enantioselektiven sulfoxid-derivaten
|
EP1615913A2
(de)
|
2003-06-10 |
2006-01-18 |
Teva Pharmaceutical Industries Limited |
Verfahren zur herstellung von (pyridinyl)methyl]sulfinyl-substituierte benzimidazoles und neue chlorierte derivate von pantoprazole
|
AU2005264864B2
(en)
|
2004-06-16 |
2011-08-11 |
Takeda Pharmaceutical Company Limited |
Multiple PPI dosage form
|
ES2441970T3
(es)
|
2004-09-13 |
2014-02-07 |
Takeda Pharmaceutical Company Limited |
Método para producir lansoprazol
|
EP1681056A1
(de)
|
2005-01-14 |
2006-07-19 |
Krka Tovarna Zdravil, D.D., Novo Mesto |
Verfahren zur Herstellung von Lansoprazol
|
KR100758600B1
(ko)
*
|
2006-01-05 |
2007-09-13 |
주식회사 대웅제약 |
란소프라졸 결정형 a의 제조방법
|
WO2008035189A1
(en)
*
|
2006-09-22 |
2008-03-27 |
Orchid Chemicals & Pharmaceuticals Limited |
A method for the purification of lansoprazole
|
EA200900985A1
(ru)
|
2007-01-31 |
2009-12-30 |
Крка, Товарна Здравил, Д. Д., Ново Место |
Способ получения оптически чистого омепразола
|
WO2009066309A2
(en)
*
|
2007-07-12 |
2009-05-28 |
Cadila Healthcare Limited |
Process for preparation of omeprazole
|
WO2009049160A1
(en)
|
2007-10-12 |
2009-04-16 |
Takeda Pharmaceuticals North America |
Methods of treating gastrointestinal disorders independent of the intake of food
|
CA2671369C
(en)
|
2008-03-10 |
2011-05-10 |
Takeda Pharmaceutical Company Limited |
Crystal of benzimidazole compound
|
ES2343935B1
(es)
*
|
2008-12-29 |
2011-04-28 |
Laboratorios Viñas S.A. |
Intermedios utiles para la obtencion de 2-(2-piridinilmetilsulfinil)-1h-benzimidazoles y procedimientos correspondientes.
|
KR20100101405A
(ko)
*
|
2009-03-09 |
2010-09-17 |
한미홀딩스 주식회사 |
비결정형의 (+)-란소프라졸 제조방법 및 이에 사용되는 (+)-란소프라졸 알코올레이트
|
WO2010134099A1
(en)
|
2009-05-21 |
2010-11-25 |
Cadila Healthcare Limited |
One pot process for preparing omeprazole and related compounds
|
CN102180865B
(zh)
*
|
2011-03-17 |
2013-01-16 |
浙江工业大学 |
一种兰索拉唑的合成方法
|
US9119769B2
(en)
|
2011-12-30 |
2015-09-01 |
The Curators Of The University Of Missouri |
Method for transforming pharmaceutical crystal forms
|
CN104203938A
(zh)
|
2012-01-21 |
2014-12-10 |
朱比兰特生命科学有限公司 |
用于制备2-吡啶基甲基亚硫酰基苯并咪唑、它们的类似物和光学活性对映体的方法
|
CN103724325B
(zh)
*
|
2013-12-10 |
2016-04-13 |
南京工业大学 |
制备亚磺酰基-1-氢-苯并咪唑衍生物的方法
|
CN104019635B
(zh)
*
|
2014-06-19 |
2015-05-27 |
上海慈瑞医药科技有限公司 |
一种兰索拉唑原料药化合物及其干燥工艺
|