ATE79474T1 - Verfahren zum in vitro-nachweis und bestimmung unbekannter pathogene oder genetischer einheiten. - Google Patents
Verfahren zum in vitro-nachweis und bestimmung unbekannter pathogene oder genetischer einheiten.Info
- Publication number
- ATE79474T1 ATE79474T1 AT85902921T AT85902921T ATE79474T1 AT E79474 T1 ATE79474 T1 AT E79474T1 AT 85902921 T AT85902921 T AT 85902921T AT 85902921 T AT85902921 T AT 85902921T AT E79474 T1 ATE79474 T1 AT E79474T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- unknown pathogens
- detection
- determination
- identification
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000001514 detection method Methods 0.000 title abstract 3
- 230000002068 genetic effect Effects 0.000 title abstract 3
- 244000052769 pathogen Species 0.000 title abstract 3
- 238000000338 in vitro Methods 0.000 title 1
- 239000000523 sample Substances 0.000 abstract 3
- 238000009396 hybridization Methods 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 230000009089 cytolysis Effects 0.000 abstract 1
- 230000002934 lysing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/06—Lysis of microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1017—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by filtration, e.g. using filters, frits, membranes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Mycology (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/619,286 US4652517A (en) | 1984-06-11 | 1984-06-11 | Methods for the in vitro detection and identification of unknown pathogens or genetic entities |
| PCT/US1985/001050 WO1986000139A1 (en) | 1984-06-11 | 1985-06-06 | Methods for the in vitro detection and identification of unknown pathogens or genetic entities |
| EP85902921A EP0188450B1 (de) | 1984-06-11 | 1985-06-06 | Verfahren zum in vitro-nachweis und bestimmung unbekannter pathogene oder genetischer einheiten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE79474T1 true ATE79474T1 (de) | 1992-08-15 |
Family
ID=24481252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85902921T ATE79474T1 (de) | 1984-06-11 | 1985-06-06 | Verfahren zum in vitro-nachweis und bestimmung unbekannter pathogene oder genetischer einheiten. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4652517A (de) |
| EP (1) | EP0188450B1 (de) |
| JP (1) | JPS61502376A (de) |
| AT (1) | ATE79474T1 (de) |
| AU (1) | AU594925B2 (de) |
| WO (1) | WO1986000139A1 (de) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5288611A (en) * | 1983-01-10 | 1994-02-22 | Gen-Probe Incorporated | Method for detecting, identifying, and quantitating organisms and viruses |
| US4806631A (en) * | 1985-09-30 | 1989-02-21 | Miles Inc. | Immobilization of nucleic acids on solvolyzed nylon supports |
| US4806546A (en) * | 1985-09-30 | 1989-02-21 | Miles Inc. | Immobilization of nucleic acids on derivatized nylon supports |
| US4888278A (en) * | 1985-10-22 | 1989-12-19 | University Of Massachusetts Medical Center | In-situ hybridization to detect nucleic acid sequences in morphologically intact cells |
| US5985549A (en) * | 1985-10-22 | 1999-11-16 | University Of Massachusetts | Non-isotopic in-situ hybridization method for detection of nucleic acids |
| EP0261955A3 (de) * | 1986-09-26 | 1989-06-07 | E.I. Du Pont De Nemours And Company | Verfahren zur Immobilisierung von DNS |
| US7138516B1 (en) | 1986-11-24 | 2006-11-21 | Gen-Probe Incorporated | Oligonucleotide probes for the detection and/or quantitation of non-viral organisms |
| US7087742B1 (en) | 1986-11-24 | 2006-08-08 | Gen-Probe Incorporated | Oligonucleotide probes for the detection and/or quantitation of non-viral organisms |
| US4977251A (en) * | 1987-01-30 | 1990-12-11 | University Of Illinois Board Of Trustees | DNA probes for identification of bacteroides species |
| ES2054797T3 (es) * | 1987-03-02 | 1994-08-16 | Gen Probe Inc | Soportes policationicos para purificar, separar e hibridar acidos nucleicos. |
| US5599667A (en) * | 1987-03-02 | 1997-02-04 | Gen-Probe Incorporated | Polycationic supports and nucleic acid purification separation and hybridization |
| IL85948A0 (en) * | 1987-04-08 | 1988-09-30 | Cambridge Bioscience Corp | Method and kit for detecting bacteria or fungi |
| AU1701488A (en) * | 1987-04-08 | 1988-11-04 | Invitron Corporation | Detection and identification of dna and/or rna in protein-containing samples |
| EP0311388B1 (de) * | 1987-10-06 | 1995-02-22 | Ortho Diagnostic Systems Inc. | Schnelles Verfahren zur Identifizierung einer spezifischen Sequenz von Nukleinsäure |
| US5294533A (en) * | 1988-07-05 | 1994-03-15 | Baylor College Of Medicine | Antisense oligonucleotide antibiotics complementary to the macromolecular synthesis operon, methods of treating bacterial infections and methods for identification of bacteria |
| GR1002090B (en) * | 1988-09-30 | 1995-12-28 | Ortho Diagnostic Systems Inc | A rapid method for identifying a specific nucleic acid sequence |
| US6242184B1 (en) | 1988-10-18 | 2001-06-05 | University Of Massachusetts | In-situ hybridization of single-copy and multiple-copy nucleic acid sequences |
| US7172863B1 (en) | 1988-12-09 | 2007-02-06 | Gen-Probe Incorporated | Nucleic acid probes and methods for detecting Neisseria gonorrhoeae |
| DE69031318D1 (de) * | 1989-03-17 | 1997-10-02 | Abbott Lab | Verfahren und Vorrichtung zur Hybridisierung von Nukleinsäure mit verbesserter Reaktionskinetik |
| DE3919393A1 (de) * | 1989-06-14 | 1990-12-20 | Hoechst Ag | Verfahren zur stabilisierung von auf festphasen immobilisierten biologisch aktiven substanzen |
| US5106730A (en) * | 1989-07-24 | 1992-04-21 | Microprobe Corporation | Lactam-containing compositions and methods useful for the hybridization of nucleic acids |
| US5700636A (en) * | 1990-10-19 | 1997-12-23 | Becton Dickinson And Company | Methods for selectively detecting microorganisms associated with vaginal infections in complex biological samples |
| ATE161893T1 (de) * | 1990-10-19 | 1998-01-15 | Microprobe Corp | Verfahren und pharmazeutische sätze zum aufspüren von mikroorganismen assoziiert mit vaginalinfektionen |
| IL102486A (en) * | 1991-10-04 | 1997-11-20 | Orgenics Ltd | Method and apparatus for detection of nucleic acid sequences with a nucleic acid probe |
| US5350695A (en) * | 1991-12-05 | 1994-09-27 | Miles Inc. | Methods for the identification and characterization of reticulocytes in whole blood |
| US5284771A (en) * | 1991-12-05 | 1994-02-08 | Miles Inc. | Reagent compositions and their use in sphering cells |
| DE4212555A1 (de) * | 1992-04-15 | 1993-10-21 | Boehringer Mannheim Gmbh | Verfahren zum Nachweis von Nukleinsäuren |
| EP1329518B1 (de) * | 1992-07-07 | 2006-11-22 | Fuso Pharmaceutical Industries Ltd. | Sonde zur Diagnose einer ansteckenden Krankheit verursacht durch Staphylococcus aureus |
| US6045996A (en) * | 1993-10-26 | 2000-04-04 | Affymetrix, Inc. | Hybridization assays on oligonucleotide arrays |
| US5658749A (en) * | 1994-04-05 | 1997-08-19 | Corning Clinical Laboratories, Inc. | Method for processing mycobacteria |
| GB9425138D0 (en) | 1994-12-12 | 1995-02-08 | Dynal As | Isolation of nucleic acid |
| ES2110916B1 (es) * | 1996-05-24 | 1998-10-01 | Ivia | Procedimiento de preparacion de dianas para la reaccion en cadena de la polimerasa (pcr). |
| US5985593A (en) * | 1996-10-11 | 1999-11-16 | Integrated Research Technology, L.L.C. | Compositions and methods for enzymatic decontamination |
| US6289229B1 (en) | 1998-01-20 | 2001-09-11 | Scimed Life Systems, Inc. | Readable probe array for in vivo use |
| GB2338236B (en) | 1998-06-13 | 2003-04-09 | Aea Technology Plc | Microbiological cell processing |
| WO2000034521A1 (en) * | 1998-12-08 | 2000-06-15 | Boston Probes, Inc. | Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices |
| DE19956820A1 (de) * | 1999-11-25 | 2001-05-31 | Roche Diagnostics Gmbh | Spezies-spezifischer Nachweis von Nukleinsäuren mittels eines Analyseelementes |
| DE10137342A1 (de) * | 2001-07-31 | 2003-03-06 | Infineon Technologies Ag | Biosensor und Verfahren zum Erfassen von makromolekularen Biopolymeren mittels mindestens einer Einheit zum Immobilisieren von makromolekularen Biopolymeren |
| US20040180445A1 (en) * | 2003-03-12 | 2004-09-16 | Domanico Michael J. | Methods and compositions for purification of nucleic acid from a host cell |
| US7150995B2 (en) * | 2004-01-16 | 2006-12-19 | Metrika, Inc. | Methods and systems for point of care bodily fluid analysis |
| KR101194112B1 (ko) * | 2004-06-07 | 2012-10-24 | 덴카 세이켄 가부시키가이샤 | 크로마토그래피식 검출 장치, 검사법 및 이것을 응용한키트 |
| US7883855B2 (en) * | 2006-07-21 | 2011-02-08 | Abbott Laboratories | Immunosuppressant drug extraction reagent for immunoassays |
| WO2008082984A2 (en) * | 2006-12-29 | 2008-07-10 | Abbott Laboratories | Non-denaturing lysis reagent for use with capture-in-solution immunoassay |
| JP4968611B2 (ja) * | 2006-12-29 | 2012-07-04 | アボット・ラボラトリーズ | 免疫抑制剤の改善された測定法 |
| US7914999B2 (en) * | 2006-12-29 | 2011-03-29 | Abbott Laboratories | Non-denaturing lysis reagent |
| JP5450092B2 (ja) | 2006-12-29 | 2014-03-26 | アボット・ラボラトリーズ | 全血中の分子または薬物の検出のための診断検査 |
| JP5592357B2 (ja) | 2008-05-27 | 2014-09-17 | ダコ・デンマーク・エー/エス | 新規なハイブリダイゼーションバッファーを用いた染色体異常の検出のための組成物及び方法 |
| US9388456B2 (en) | 2009-02-26 | 2016-07-12 | Dako Denmark A/S | Compositions and methods for performing a stringent wash step in hybridization applications |
| EP2333105A1 (de) | 2009-12-08 | 2011-06-15 | Koninklijke Philips Electronics N.V. | Selektive Lyse von Zellen |
| US10662465B2 (en) * | 2011-09-30 | 2020-05-26 | Agilent Technologies, Inc. | Hybridization compositions and methods using formamide |
| EP2768974B1 (de) | 2011-10-21 | 2017-07-19 | Dako Denmark A/S | Hybridisierungszusammensetzungen und -verfahren |
| WO2014018195A1 (en) * | 2012-06-21 | 2014-01-30 | Monsanto Technology Llc | Lysis buffer and methods for extraction of dna from plant material |
| EP3074539B1 (de) | 2014-06-13 | 2018-01-10 | Q-Linea AB | Verfahren für den nachweis und die charakterisierung eines mikroorganismus |
| GB201507026D0 (en) | 2015-04-24 | 2015-06-10 | Linea Ab Q | Medical sample transportation container |
| GB2554767A (en) | 2016-04-21 | 2018-04-11 | Q Linea Ab | Detecting and characterising a microorganism |
| US10428370B2 (en) | 2016-09-15 | 2019-10-01 | Sun Genomics, Inc. | Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample |
| US11959125B2 (en) | 2016-09-15 | 2024-04-16 | Sun Genomics, Inc. | Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4358535A (en) * | 1980-12-08 | 1982-11-09 | Board Of Regents Of The University Of Washington | Specific DNA probes in diagnostic microbiology |
| US4407942A (en) * | 1981-01-29 | 1983-10-04 | Atomic Energy Of Canada Limited | Fluorescent detection of DNA damage |
| US4689295A (en) * | 1983-01-20 | 1987-08-25 | Integrated Genetics, Inc. | Test for Salmonella |
| GB8332525D0 (en) * | 1983-12-06 | 1984-01-11 | Secr Defence | Conformable fascine |
-
1984
- 1984-06-11 US US06/619,286 patent/US4652517A/en not_active Expired - Fee Related
-
1985
- 1985-06-06 AU AU44313/85A patent/AU594925B2/en not_active Ceased
- 1985-06-06 WO PCT/US1985/001050 patent/WO1986000139A1/en not_active Ceased
- 1985-06-06 AT AT85902921T patent/ATE79474T1/de active
- 1985-06-06 EP EP85902921A patent/EP0188450B1/de not_active Expired - Lifetime
- 1985-06-06 JP JP60502509A patent/JPS61502376A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS61502376A (ja) | 1986-10-23 |
| WO1986000139A1 (en) | 1986-01-03 |
| EP0188450A4 (de) | 1989-02-02 |
| US4652517A (en) | 1987-03-24 |
| AU4431385A (en) | 1986-01-10 |
| JPH0430279B2 (de) | 1992-05-21 |
| EP0188450B1 (de) | 1992-08-12 |
| AU594925B2 (en) | 1990-03-22 |
| EP0188450A1 (de) | 1986-07-30 |
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