ATE7853T1 - Oberflaechenaktive zusammensetzungen fuer die lunge. - Google Patents

Oberflaechenaktive zusammensetzungen fuer die lunge.

Info

Publication number
ATE7853T1
ATE7853T1 AT81108298T AT81108298T ATE7853T1 AT E7853 T1 ATE7853 T1 AT E7853T1 AT 81108298 T AT81108298 T AT 81108298T AT 81108298 T AT81108298 T AT 81108298T AT E7853 T1 ATE7853 T1 AT E7853T1
Authority
AT
Austria
Prior art keywords
surfactant composition
synthetic
lung
fatty alcohol
surface active
Prior art date
Application number
AT81108298T
Other languages
German (de)
English (en)
Inventor
John Allen Clements
Original Assignee
The Regents Of The University Of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of California filed Critical The Regents Of The University Of California
Application granted granted Critical
Publication of ATE7853T1 publication Critical patent/ATE7853T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Dental Preparations (AREA)
AT81108298T 1980-10-24 1981-10-14 Oberflaechenaktive zusammensetzungen fuer die lunge. ATE7853T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/200,216 US4312860A (en) 1980-10-24 1980-10-24 Lung surfactant compositions
EP81108298A EP0050793B1 (en) 1980-10-24 1981-10-14 Lung surfactant compositions

Publications (1)

Publication Number Publication Date
ATE7853T1 true ATE7853T1 (de) 1984-06-15

Family

ID=22740789

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81108298T ATE7853T1 (de) 1980-10-24 1981-10-14 Oberflaechenaktive zusammensetzungen fuer die lunge.

Country Status (9)

Country Link
US (1) US4312860A (https=)
EP (1) EP0050793B1 (https=)
JP (1) JPS5799524A (https=)
AT (1) ATE7853T1 (https=)
BG (1) BG60737B2 (https=)
CA (1) CA1184503A (https=)
CS (1) CS384991A3 (https=)
DE (2) DE19375071I2 (https=)
NL (1) NL930059I2 (https=)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3229179C2 (de) * 1982-08-05 1986-04-17 A. Nattermann & Cie GmbH, 5000 Köln Lungensurfactant
JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
US5840527A (en) * 1984-12-11 1998-11-24 Byk Gulden Lomberg Chemische Fabrik Gmbh Recombinant alveolar surfactant protein
US5169761A (en) * 1984-12-11 1992-12-08 California Biotechnology Inc. Dna encoding and expression systems for alveolar surfactant proteins
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
US4659805A (en) * 1984-12-11 1987-04-21 California Biotechnology, Inc. Recombinant alveolar surfactant protein
JPS63500175A (ja) * 1985-05-22 1988-01-21 リポソ−ム　テクノロジ−，インコ−ポレイテツド リポソ−ム吸入法および吸入システム
US5110806A (en) * 1985-06-26 1992-05-05 The Regents Of The University Of California Lung surfactant compositions
US4826821A (en) * 1985-06-26 1989-05-02 The Regents Of The University Of California Lung surfactant compositions
FR2586587B1 (fr) * 1985-08-30 1987-10-23 Adir Nouveaux surfactants artificiels, leur preparation et les compositions pharmaceutiques qui les contiennent.
US4812314A (en) * 1986-02-24 1989-03-14 Yissum Research & Dev. Co. Of The Hebrew Univ. Of Jerusalem And Hadassah Medical Organization Lipid replacement therapy
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
US5032585A (en) * 1987-02-17 1991-07-16 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy
IT1203873B (it) * 1987-04-08 1989-02-23 Chiesi Farma Spa Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e
US4861756A (en) * 1988-03-08 1989-08-29 Merrell Dow Pharmaceuticals Inc. Synthetic pulmonary surfactant
US5207220A (en) * 1989-12-12 1993-05-04 Burroughs Wellcome Co. Method for administering pharmaceuticals, including liquid surfactant, to the lungs
US5614216A (en) * 1990-10-17 1997-03-25 The Liposome Company, Inc. Synthetic lung surfactant
GB9120005D0 (en) * 1991-09-19 1991-11-06 Wellcome Found Method of administering phospholipid dispersions
US6235308B1 (en) 1994-06-10 2001-05-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method of treating hypertension
US5622715A (en) * 1994-06-10 1997-04-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method of improving renal function
US5698537A (en) * 1996-06-18 1997-12-16 Clarion Pharmaceuticals Inc. Method of lowering the viscosity of mucus
US5883084A (en) * 1998-06-08 1999-03-16 Clarion Pharmaceuticals Inc. Treatment of respiratory diseases utilizing α-tocopheryl-phosphocholine
US6180142B1 (en) * 1998-08-21 2001-01-30 The Regents Of The University Of California Reduction of surfactant inactivation in pulmonary surfactant therapy
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6630126B2 (en) * 2000-03-13 2003-10-07 Medi-Physics, Inc. Diagnostic procedures using direct injection of gaseous hyperpolarized 129Xe and associated systems and products
GB0026239D0 (en) * 2000-10-26 2000-12-13 Britannia Pharmaceuticals Ltd Surface active lipids in treatment of wet lung
US8029815B2 (en) * 2004-04-28 2011-10-04 Elford Howard L Methods for treating or preventing restenosis and other vascular proliferative disorders
US7638493B2 (en) * 2004-04-29 2009-12-29 Sannamu Lee Artificial pulmonary surfactant compositions and use of the same
US8551534B2 (en) 2007-10-10 2013-10-08 Parion Sciences, Inc. Inhaled hypertonic saline delivered by a heated nasal cannula
US8778383B2 (en) 2011-06-07 2014-07-15 Parion Sciences, Inc. Methods of treatment
US8945605B2 (en) 2011-06-07 2015-02-03 Parion Sciences, Inc. Aerosol delivery systems, compositions and methods
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
MX2014014648A (es) 2012-05-29 2015-09-04 Parion Sciences Inc Aminoamidas tipo dendrimero que poseen actividad bloqueadora del canal de sodio para el tratamiento de ojo reseco y otras enfermedades mucosas.
SG10201708931XA (en) 2012-12-17 2017-12-28 Parion Sciences Inc Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration
ES2674665T3 (es) 2012-12-17 2018-07-03 Parion Sciences, Inc. Compuestos de 3,5-diamino-6-cloro-N-(N-(4-fenilbutilo)carbamimidoilo)-pirazina-2-carboxamida
RU2018138195A (ru) 2012-12-17 2018-12-18 Пэрион Сайенсиз, Инк. Соединения 3,5-диамино-6-хлор-n-(n-(4- фенилбутил)карбамимидоил)пиразин-2-карбоксамида
US11219843B2 (en) * 2019-07-08 2022-01-11 Nik Paya Karen Pharmed Extraction of animal-derived pulmonary surfactants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE388023C (de) * 1922-02-14 1924-01-07 Chem Fab Verfahren zur Herstellung von waesserigen Lezithinemulsionen
US3577446A (en) * 1968-09-09 1971-05-04 American Home Prod Phosphatidylalkanolamine derivatives
DE2629135A1 (de) * 1976-06-29 1978-01-12 Nattermann A & Cie Neue phospholipid-derivate von prostaglandinen und verfahren zu ihrer herstellung
DE2900300A1 (de) * 1979-01-05 1980-07-17 Lebrecht Von Dr Klitzing Verfahren einer prophylaxe zur vermeidung des atemnotsyndroms bei fruehgeborenen und bei der schocklunge

Also Published As

Publication number Publication date
JPH0343252B2 (https=) 1991-07-01
EP0050793B1 (en) 1984-06-13
BG60737B2 (bg) 1996-01-31
NL930059I1 (nl) 1993-09-01
JPS5799524A (en) 1982-06-21
DE19375071I2 (de) 2006-05-04
NL930059I2 (nl) 1994-01-03
CA1184503A (en) 1985-03-26
CS384991A3 (en) 1992-10-14
EP0050793A1 (en) 1982-05-05
DE3164207D1 (en) 1984-07-19
US4312860A (en) 1982-01-26

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