ATE78167T1 - Heilmittel fuer wunden. - Google Patents

Heilmittel fuer wunden.

Info

Publication number
ATE78167T1
ATE78167T1 AT85905980T AT85905980T ATE78167T1 AT E78167 T1 ATE78167 T1 AT E78167T1 AT 85905980 T AT85905980 T AT 85905980T AT 85905980 T AT85905980 T AT 85905980T AT E78167 T1 ATE78167 T1 AT E78167T1
Authority
AT
Austria
Prior art keywords
wounds
cells
substance
remedies
capillary
Prior art date
Application number
AT85905980T
Other languages
English (en)
Inventor
David R Knighton
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Application granted granted Critical
Publication of ATE78167T1 publication Critical patent/ATE78167T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0033—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/64—Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Inorganic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Eye Examination Apparatus (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
AT85905980T 1984-11-29 1985-11-08 Heilmittel fuer wunden. ATE78167T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US67647184A 1984-11-29 1984-11-29
US78620685A 1985-10-10 1985-10-10
EP85905980A EP0202298B1 (de) 1984-11-29 1985-11-08 Heilmittel für wunden
PCT/US1985/002205 WO1986003122A1 (en) 1984-11-29 1985-11-08 Wound healing agents

Publications (1)

Publication Number Publication Date
ATE78167T1 true ATE78167T1 (de) 1992-08-15

Family

ID=27101561

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85905980T ATE78167T1 (de) 1984-11-29 1985-11-08 Heilmittel fuer wunden.

Country Status (16)

Country Link
EP (2) EP0202298B1 (de)
AT (1) ATE78167T1 (de)
AU (1) AU596954B2 (de)
CA (1) CA1261259A (de)
CH (1) CH673774A5 (de)
DE (2) DE3586355T2 (de)
DK (1) DK165169C (de)
FI (1) FI85219C (de)
GB (1) GB2248777B (de)
HU (1) HUT42329A (de)
IE (1) IE57894B1 (de)
IL (1) IL77096A (de)
NL (1) NL8520384A (de)
NO (1) NO170194C (de)
SE (1) SE8603228L (de)
WO (1) WO1986003122A1 (de)

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US5187263A (en) * 1984-10-12 1993-02-16 Zymogenetics, Inc. Expression of biologically active PDGE analogs in eucaryotic cells
EP0487116B1 (de) * 1984-10-12 1999-12-29 ZymoGenetics, Inc. Von Blutplättchen abstammende biologisch aktive Analoga eines Wachstumsfaktors in eukaryotischen Zellen
US5498600A (en) * 1984-10-12 1996-03-12 Zymogenetics, Inc. Biologically active mosaic proteins
US5045633A (en) * 1985-02-25 1991-09-03 Zymogenetics, Inc. Expression of biologically active PDGF analogs in eucaryotic cells
IL84911A (en) * 1987-12-22 1993-04-04 Yissum Res Dev Co Processes for the preparation of collagen products, and pharmaceutical compositions containing the same
US5814602A (en) * 1988-03-17 1998-09-29 Novo Nordisk A/S Heparin-binding proteins
US4900541A (en) * 1988-05-06 1990-02-13 Govier William C Sunscreen composition
IT1217938B (it) * 1988-06-28 1990-03-30 Girolamo Sirchia Procedimento per la preparazione e la conservazione di concentrati eritrocitari e piastrinici
IL95641A0 (en) * 1989-09-15 1991-06-30 Curative Tech Inc Preparation of a platelet releasate product
US5599558A (en) * 1989-09-15 1997-02-04 Curative Technologies, Inc. Selecting amounts of platelet releasate for efficacious treatment of tissue
US6197325B1 (en) * 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US7189410B1 (en) 1990-11-27 2007-03-13 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6559119B1 (en) 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
US6117425A (en) * 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
DE69132918T2 (de) * 1990-11-27 2002-10-31 American National Red Cross, Washington Gewebeabdeckung und wachstumsfaktor enthaltende verbindungen zur förderung beschleunigter wundheilung
US5171579A (en) * 1991-10-11 1992-12-15 Genetics Institute, Inc. Formulations of blood clot-polymer matrix for delivery of osteogenic proteins
IL105529A0 (en) * 1992-05-01 1993-08-18 Amgen Inc Collagen-containing sponges as drug delivery for proteins
FR2691911B1 (fr) * 1992-06-05 1994-11-25 Delmas Olivier Dispositif permettant l'obtention d'un surnageant de thrombocytes activés, procédé mettant en Óoeuvre le dispositif et surnageant obtenu.
FR2696095B1 (fr) * 1992-09-30 1994-11-25 Inoteb Colle biologique à base de protéines coagulables par la thrombine, enrichie en facteurs plaquettaires, sa préparation et son application.
EP0637450A3 (de) * 1993-08-04 1995-04-05 Collagen Corp Verfahren und Zusammensetzung zur Wiederbelebung von Nerbgewebe.
WO1995015763A1 (en) * 1993-12-08 1995-06-15 Universite De Montreal Process for the preparation of serum and platelet growth factors extract
US5733545A (en) * 1995-03-03 1998-03-31 Quantic Biomedical Partners Platelet glue wound sealant
CZ365097A3 (cs) * 1995-05-24 1998-02-18 Cellfactors Plc. Činidla pro diferenciaci buněk
WO1996039208A1 (en) * 1995-06-06 1996-12-12 Quantic Biomedical Partners Device and method for concentrating plasma
US5834418A (en) * 1996-03-20 1998-11-10 Theratechnologies, Inc. Process for the preparation of platelet growth factors extract
US6102926A (en) 1996-12-02 2000-08-15 Angiotrax, Inc. Apparatus for percutaneously performing myocardial revascularization having means for sensing tissue parameters and methods of use
US6120520A (en) * 1997-05-27 2000-09-19 Angiotrax, Inc. Apparatus and methods for stimulating revascularization and/or tissue growth
US6051008A (en) 1996-12-02 2000-04-18 Angiotrax, Inc. Apparatus having stabilization members for percutaneously performing surgery and methods of use
US6117444A (en) * 1997-04-10 2000-09-12 Brigham & Women's Hospital Polyethylene glycol/microfibrillar collagen composite serves as a resorbable hemostatic agent
AT407484B (de) 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
US6762336B1 (en) 1998-01-19 2004-07-13 The American National Red Cross Hemostatic sandwich bandage
US6524568B2 (en) 1998-06-22 2003-02-25 Cytomedix, Inc. Enriched platelet wound healant
NZ509122A (en) * 1998-06-22 2003-09-26 Cytomedix Inc Wound healant comprising activated growth from platelets and ascorbic acid
US6432119B1 (en) 1999-03-17 2002-08-13 Angiotrax, Inc. Apparatus and methods for performing percutaneous myocardial revascularization and stimulating angiogenesis using autologous materials
US8293530B2 (en) 2006-10-17 2012-10-23 Carnegie Mellon University Method and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
US8529956B2 (en) 2002-03-18 2013-09-10 Carnell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
RU2308954C2 (ru) * 2002-05-09 2007-10-27 Медиджинез Фармацевтическая композиция для лечения ран, содержащая плазму или сыворотку крови
AU2003270401B2 (en) 2002-09-10 2008-03-13 American National Red Cross Hemostatic dressing
DE112004002847T5 (de) * 2004-05-05 2007-04-05 Synthes Gmbh Verwendung von Blutplättchen oder blutblättchenreichem Plasma (PRP)
US8529961B2 (en) 2006-10-17 2013-09-10 Carmell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
US20090075891A1 (en) 2007-08-06 2009-03-19 Macphee Martin Methods and dressings for sealing internal injuries
WO2020112963A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
US20200224164A1 (en) 2018-11-30 2020-07-16 Cellphire, Inc. Platelets as delivery agents
IL322149A (en) 2019-05-03 2025-09-01 Cellphire Inc Materials and methods for manufacturing blood products
IL290586B1 (en) 2019-08-16 2025-08-01 Cellphire Inc Thrombosomes as an antiplatelet agent reversal agent
CA3170196A1 (en) 2020-02-04 2021-08-12 Cellphire, Inc. Anti-fibrinolytic loaded platelets
TWI787761B (zh) * 2020-03-20 2022-12-21 台灣粒線體應用技術股份有限公司 粒線體用於促進傷口修復及/或傷口癒合之用途
US20220273724A1 (en) 2021-02-17 2022-09-01 Cellphire Inc. Freeze-dried platelet derivative compositions for treating antiplatelet induced coagulopathy
CN114831770A (zh) * 2022-05-20 2022-08-02 上海浦灵生物科技有限公司 一种肺动脉高压非人灵长类动物模型及其构建方法

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GB1195061A (en) * 1966-05-27 1970-06-17 Fmc Corp Coated Structures and Methods of Forming Them.
FR2472385A1 (fr) * 1979-12-27 1981-07-03 Sederma Sa Nouveaux extraits biologiques utilisables en cosmetologie, et procedes d'obtention de ces extraits
FR2533438B2 (fr) * 1979-12-27 1986-03-07 Sederma Sarl Utilisation en cosmetologie des facteurs de croissance et d'extraits biologiques contenant ceux-ci
DE3110560A1 (de) * 1981-03-18 1982-10-14 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen "angiotropine der leukozyten und des entzuendungsgewebes: eine neue klasse natuerlicher chemotropischer mitogene fuer das richtungswachstum von blutgefaessen und zur neovaskularisierung von geweben"
US4479896A (en) * 1981-12-11 1984-10-30 Antoniades Harry N Method for extraction localization and direct recovery of platelet derived growth factor
US4444760A (en) * 1983-06-17 1984-04-24 Merck & Co., Inc. Purification and characterization of a protein fibroblast growth factor

Also Published As

Publication number Publication date
WO1986003122A1 (en) 1986-06-05
EP0202298A4 (de) 1988-07-04
DE3586355T2 (de) 1993-01-14
DK357386A (da) 1986-07-28
IE852810L (en) 1986-05-29
SE8603228D0 (sv) 1986-07-25
EP0383363A2 (de) 1990-08-22
NO170194B (no) 1992-06-15
AU5094985A (en) 1986-06-18
NO862964D0 (no) 1986-07-23
NO862964L (no) 1986-07-23
FI863087A0 (fi) 1986-07-28
DE3586355D1 (de) 1992-08-20
FI85219B (fi) 1991-12-13
EP0383363A3 (de) 1990-10-03
DK165169C (da) 1993-03-01
AU596954B2 (en) 1990-05-24
DK357386D0 (da) 1986-07-28
CA1261259A (en) 1989-09-26
HUT42329A (en) 1987-07-28
CH673774A5 (de) 1990-04-12
EP0202298A1 (de) 1986-11-26
FI85219C (fi) 1992-03-25
GB2248777B (en) 1993-06-30
IE57894B1 (en) 1993-05-05
NL8520384A (nl) 1986-10-01
FI863087L (fi) 1986-07-28
DE3590594T1 (de) 1987-01-29
IL77096A (en) 1993-01-31
GB8617658D0 (en) 1986-08-28
NO170194C (no) 1992-09-23
DK165169B (da) 1992-10-19
EP0202298B1 (de) 1992-07-15
SE8603228L (sv) 1986-07-25
GB2248777A (en) 1992-04-22

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee