ATE77748T1 - Solubilisierung wasserabweisender verbindungen mittels lysophospholipid. - Google Patents

Solubilisierung wasserabweisender verbindungen mittels lysophospholipid.

Info

Publication number
ATE77748T1
ATE77748T1 AT87901210T AT87901210T ATE77748T1 AT E77748 T1 ATE77748 T1 AT E77748T1 AT 87901210 T AT87901210 T AT 87901210T AT 87901210 T AT87901210 T AT 87901210T AT E77748 T1 ATE77748 T1 AT E77748T1
Authority
AT
Austria
Prior art keywords
lysophospholipid
solubilization
water
repellent compounds
composition
Prior art date
Application number
AT87901210T
Other languages
English (en)
Inventor
Colin P S Tilcock
Pieter R Cullis
Michael J Hope
Andrew S Janoff
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Application granted granted Critical
Publication of ATE77748T1 publication Critical patent/ATE77748T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials Applied To Surfaces To Minimize Adherence Of Mist Or Water (AREA)
AT87901210T 1986-01-22 1987-01-22 Solubilisierung wasserabweisender verbindungen mittels lysophospholipid. ATE77748T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/821,366 US4923854A (en) 1986-01-22 1986-01-22 Solubilization of hydrophobic materials using lysophospholipid
PCT/US1987/000143 WO1987004347A1 (en) 1986-01-22 1987-01-22 Solubilization of hydrophobic materials using lysophospholipid
EP87901210A EP0256090B1 (de) 1986-01-22 1987-01-22 Solubilisierung wasserabweisender verbindungen mittels lysophospholipid

Publications (1)

Publication Number Publication Date
ATE77748T1 true ATE77748T1 (de) 1992-07-15

Family

ID=25233191

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87901210T ATE77748T1 (de) 1986-01-22 1987-01-22 Solubilisierung wasserabweisender verbindungen mittels lysophospholipid.

Country Status (7)

Country Link
US (1) US4923854A (de)
EP (1) EP0256090B1 (de)
JP (2) JP2543114B2 (de)
AT (1) ATE77748T1 (de)
CA (1) CA1303990C (de)
DE (1) DE3780100T2 (de)
WO (1) WO1987004347A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
EP0355331A3 (de) * 1988-07-01 1991-08-14 G.D. Searle & Co. Poly(aminoalkyl)aminocarbonylaminoacylaminodiolaminosäure als antihypertensive Agenzien
FI893212L (fi) * 1988-07-01 1990-01-02 Searle & Co Antihypertensiva aminoalkylaminokarbo- nylaminodiolaminsyraderivat.
US5234912A (en) * 1989-02-14 1993-08-10 Incyte Pharmaceuticals, Inc. Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof
DK0458894T3 (da) * 1989-02-17 1996-10-07 Liposome Co Inc Lipidexcipiens til nasal afgivelse og topisk påføring
JPH02273536A (ja) * 1989-04-13 1990-11-08 Yakult Honsha Co Ltd 界面活性剤およびその製造法
GB2237143A (en) * 1989-09-15 1991-04-24 Philips Electronic Associated Two-terminal non-linear devices and their fabrication
US6165997A (en) * 1997-11-20 2000-12-26 Statens Serum Institut Phospholipids having antimicrobial activity with or without the presence of antimicrobials
KR100472297B1 (ko) * 2001-09-27 2005-03-07 주식회사 두산 리소인지질의 수용성 조성물

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2009343C3 (de) * 1970-02-27 1980-10-23 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen Verwendung von Lysolecithinen als immunologische Adjuvantien
FR2374910A1 (fr) * 1976-10-23 1978-07-21 Choay Sa Preparation a base d'heparine, comprenant des liposomes, procede pour l'obtenir et medicaments contenant de telles preparations
JPS54117034A (en) * 1978-02-28 1979-09-11 Nippon Shoji Kk Treating agent for consciousness and perception motion disorder
GB2046092B (en) * 1979-03-05 1983-11-02 Toyama Chemical Co Ltd Pharmaceutical composition containing a lysophospholid and a phospholipid
JPS57179114A (en) * 1981-04-25 1982-11-04 Green Cross Corp:The Acetylsalicylic acid liposome preparation
DE3374837D1 (en) * 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
US4485054A (en) * 1982-10-04 1984-11-27 Lipoderm Pharmaceuticals Limited Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
JPS59163315A (ja) * 1983-03-09 1984-09-14 Mitsui Pharmaceut Inc カルモフ−ル含有リポソ−ム
US4588578A (en) * 1983-08-08 1986-05-13 The Liposome Company, Inc. Lipid vesicles prepared in a monophase
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
EP0153955A1 (de) * 1983-09-06 1985-09-11 Health Research, Inc. Verfahren zum verabreichen von liposomen zum herabsetzen der toxizität eines antitumor-arzneimittels

Also Published As

Publication number Publication date
EP0256090A1 (de) 1988-02-24
JP2533755B2 (ja) 1996-09-11
WO1987004347A1 (en) 1987-07-30
EP0256090A4 (de) 1988-04-06
EP0256090B1 (de) 1992-07-01
DE3780100T2 (de) 1992-12-24
JPH0899907A (ja) 1996-04-16
JPS63502433A (ja) 1988-09-14
JP2543114B2 (ja) 1996-10-16
DE3780100D1 (de) 1992-08-06
US4923854A (en) 1990-05-08
CA1303990C (en) 1992-06-23

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ATE77748T1 (de) Solubilisierung wasserabweisender verbindungen mittels lysophospholipid.
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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee