ATE71372T1 - Benzothiazol-derivat und es als aktiven bestandteil enthaltendes antirheumatisches mittel. - Google Patents

Benzothiazol-derivat und es als aktiven bestandteil enthaltendes antirheumatisches mittel.

Info

Publication number
ATE71372T1
ATE71372T1 AT88112722T AT88112722T ATE71372T1 AT E71372 T1 ATE71372 T1 AT E71372T1 AT 88112722 T AT88112722 T AT 88112722T AT 88112722 T AT88112722 T AT 88112722T AT E71372 T1 ATE71372 T1 AT E71372T1
Authority
AT
Austria
Prior art keywords
active ingredient
agent containing
benzothiazole derivative
rheumatic agent
benzothiazole
Prior art date
Application number
AT88112722T
Other languages
German (de)
English (en)
Inventor
Atsushi Imamura
Noriyuki Hori
Tadayuki Saito
Noriyasu Nishimura
Masami Ohashi
Kohichiro Yoshino
Original Assignee
Kanebo Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanebo Ltd filed Critical Kanebo Ltd
Application granted granted Critical
Publication of ATE71372T1 publication Critical patent/ATE71372T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AT88112722T 1987-08-07 1988-08-04 Benzothiazol-derivat und es als aktiven bestandteil enthaltendes antirheumatisches mittel. ATE71372T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP62198669A JPH0670025B2 (ja) 1987-08-07 1987-08-07 ベンゾチアゾ−ル誘導体および該化合物を有効成分とする抗リウマチ剤
EP88112722A EP0306708B1 (en) 1987-08-07 1988-08-04 Novel benzothiazole and antirheumatic agent comprising it as an active ingredient

Publications (1)

Publication Number Publication Date
ATE71372T1 true ATE71372T1 (de) 1992-01-15

Family

ID=16395075

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88112722T ATE71372T1 (de) 1987-08-07 1988-08-04 Benzothiazol-derivat und es als aktiven bestandteil enthaltendes antirheumatisches mittel.

Country Status (8)

Country Link
US (1) US4910211A (forum.php)
EP (1) EP0306708B1 (forum.php)
JP (1) JPH0670025B2 (forum.php)
KR (1) KR930009790B1 (forum.php)
AT (1) ATE71372T1 (forum.php)
DE (1) DE3867572D1 (forum.php)
ES (1) ES2039522T3 (forum.php)
GR (1) GR3004018T3 (forum.php)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5428052A (en) * 1984-09-19 1995-06-27 Centre Internationale De Recherches Dermatologiques (C.I.R.D.) Aromatic heterocyclic derivatives and their therapeutic and cosmetic use
US5260295A (en) * 1984-09-19 1993-11-09 Centre International De Recherches Dermatologiques (C.I.R.D.) Aromatic heterocyclic derivatives and their therapeutic and cosmetic use
ATE159760T1 (de) * 1988-07-08 1997-11-15 Jbl Scient Inc Herstellung und verwendung von fluoreszierenden benzothiazolderivaten
US5254692A (en) * 1990-04-06 1993-10-19 Bayer Aktiengesellschaft 2,6-dialkyl-4-(benzothiazol- or benzoxazol-7-yl)-1,4-dihydropyridines
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
PL319605A1 (en) * 1994-10-12 1997-08-18 Euro Celtique Sa Novel benzoxazoles
US5665737B1 (en) * 1994-10-12 1999-02-16 Euro Celtique Sa Substituted benzoxazoles
US6372770B1 (en) 1994-10-12 2002-04-16 Euro-Celtique, S.A. Benzoxazoles
EP0799040B1 (en) * 1994-12-13 2003-08-20 Euroceltique S.A. Trisubstituted thioxanthines
ATE247116T1 (de) * 1994-12-13 2003-08-15 Euro Celtique Sa Arylthioxanthine
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US6013659A (en) * 1998-09-04 2000-01-11 University Of Pittsburgh Methods of reducing tumor colony number using novel benzothiazole compounds
EP1345914A1 (en) * 2000-12-22 2003-09-24 AstraZeneca AB Therapeutic compounds
GB0111872D0 (en) * 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
AU2002353739A1 (en) * 2001-11-28 2003-06-10 Astrazeneca Ab Therapeutic compounds
US20080026984A1 (en) * 2002-02-04 2008-01-31 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
US7968605B2 (en) * 2002-02-04 2011-06-28 ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
RU2004126950A (ru) * 2002-02-04 2005-06-27 АЛФАМА-Инвестигасау и Дезенволвименту де Продутош Фармасеутикуш Лда. (PT) Использование выделяющих co соединений при изготовлении лекарственного средства для лечения воспалительных заболеваний
CN100338073C (zh) 2002-03-20 2007-09-19 麦它波莱克斯股份有限公司 取代的苯乙酸
GB2395432B (en) * 2002-11-20 2005-09-14 Northwick Park Inst For Medica Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
US20070207217A1 (en) * 2003-02-03 2007-09-06 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Method for treating a mammal by administration of a compound having the ability to release CO
US7199259B2 (en) * 2003-06-20 2007-04-03 Metabolex, Inc. Resolution of α-(phenoxy)phenylacetic acid derivatives
WO2005013691A1 (en) * 2003-08-04 2005-02-17 Hemocorm Limited Use of boranocarbonates for the therapeutic delivery of carbon monoxide
US7323480B2 (en) 2004-05-25 2008-01-29 Metabolex, Inc. Substituted triazoles as modulators of PPAR and methods of their preparation
US20060014785A1 (en) * 2004-05-25 2006-01-19 Metabolex, Inc. Bicyclic, substituted triazoles as modulators of ppar and methods of their preparation
EP2583678A3 (en) 2004-06-24 2013-11-13 Novartis Vaccines and Diagnostics, Inc. Small molecule immunopotentiators and assays for their detection
US7714131B2 (en) 2005-09-23 2010-05-11 Metabolex, Inc. Process for the stereoselective preparation of (−)-halofenate and derivatives thereof
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
JP5978291B2 (ja) 2011-04-19 2016-08-24 アルファーマ インコーポレイテッドＡｌｆａｍａ，Ｉｎｃ． 一酸化炭素放出分子およびその使用
ES2628634T3 (es) 2011-07-21 2017-08-03 Alfama, Inc. Moléculas liberadoras de monóxido de carbono-rutenio y usos de las mismas
CN112004798A (zh) * 2019-01-07 2020-11-27 江苏凯迪恩医药科技有限公司 一种苯甲酰胺类化合物、中间体、制备方法及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035757A1 (en) * 1969-02-25 1970-12-24 Roussel Uclaf Novel 4-carboxy-4,5,6,7-tetrahydro benzothia- - zole derivs
US3816443A (en) * 1972-02-17 1974-06-11 Merck & Co Inc 4-(benzothiazol-2-yl)fluoro phenyl-acetic acids
US3895028A (en) * 1972-09-12 1975-07-15 Tokyo Tanabe Co Alpha-(2-phenylbenzothiazol-5-yl)propionic acid
JPS59121704A (ja) * 1982-12-28 1984-07-13 三菱電線工業株式会社 耐水トリ−性電気絶縁性組成物

Also Published As

Publication number Publication date
KR890003720A (ko) 1989-04-17
KR930009790B1 (ko) 1993-10-11
US4910211A (en) 1990-03-20
JPS6442476A (en) 1989-02-14
ES2039522T3 (es) 1993-10-01
JPH0670025B2 (ja) 1994-09-07
EP0306708B1 (en) 1992-01-08
DE3867572D1 (de) 1992-02-20
GR3004018T3 (forum.php) 1993-03-31
EP0306708A1 (en) 1989-03-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee