ATE62408T1 - Arzneimittel mit langsamer wirkstofffreisetzung. - Google Patents

Arzneimittel mit langsamer wirkstofffreisetzung.

Info

Publication number
ATE62408T1
ATE62408T1 AT86113193T AT86113193T ATE62408T1 AT E62408 T1 ATE62408 T1 AT E62408T1 AT 86113193 T AT86113193 T AT 86113193T AT 86113193 T AT86113193 T AT 86113193T AT E62408 T1 ATE62408 T1 AT E62408T1
Authority
AT
Austria
Prior art keywords
tryptophan
pharmaceutical composition
fumaric acid
slow
release
Prior art date
Application number
AT86113193T
Other languages
English (en)
Inventor
Yoshimitsu Iida
Shuji Sumida
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE62408T1 publication Critical patent/ATE62408T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT86113193T 1985-09-26 1986-09-25 Arzneimittel mit langsamer wirkstofffreisetzung. ATE62408T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21327785 1985-09-26

Publications (1)

Publication Number Publication Date
ATE62408T1 true ATE62408T1 (de) 1991-04-15

Family

ID=16636441

Family Applications (2)

Application Number Title Priority Date Filing Date
AT86113193T ATE62408T1 (de) 1985-09-26 1986-09-25 Arzneimittel mit langsamer wirkstofffreisetzung.
AT90107877T ATE108647T1 (de) 1985-09-26 1986-09-25 Arzneimittel mit langsamer wirkstofffreisetzung.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT90107877T ATE108647T1 (de) 1985-09-26 1986-09-25 Arzneimittel mit langsamer wirkstofffreisetzung.

Country Status (15)

Country Link
US (1) US5188840A (de)
EP (2) EP0218148B1 (de)
JP (1) JPH0772142B2 (de)
KR (1) KR950010145B1 (de)
AT (2) ATE62408T1 (de)
AU (1) AU587281B2 (de)
CA (1) CA1282327C (de)
DE (2) DE3678661D1 (de)
DK (2) DK166478B1 (de)
ES (1) ES2001993A6 (de)
FI (1) FI86146C (de)
HK (1) HK65393A (de)
IE (2) IE81099B1 (de)
NO (1) NO175763C (de)
SG (1) SG64993G (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE8429928U1 (de) * 1984-10-11 1986-02-13 Sträter, Fritz, 5882 Meinerzhagen Konzepthalter zur Anwendung an Schreib-, Zeichen-, Bildschirmarbeitsplätzen und dgl.
KR940000232B1 (ko) * 1986-01-17 1994-01-12 쥬우가이세이야꾸 가부시끼가이샤 니코란딜 제제의 안정화 방법
US5057317A (en) * 1987-03-24 1991-10-15 Chugai Seiyaku Kabushiki Kaisha Slow-release pharmaceutical agent
CA1323833C (en) * 1987-04-28 1993-11-02 Yatindra M. Joshi Pharmaceutical compositions in the form of beadlets and method
SE509029C2 (sv) * 1988-08-16 1998-11-30 Ss Pharmaceutical Co Långtidsverkande diklofenak-natriumpreparat
IT1256022B (it) * 1992-06-08 1995-11-20 Preparazioni farmaceutiche stabili di nicorandil
IT1255522B (it) * 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
US6183778B1 (en) 1993-09-21 2001-02-06 Jagotec Ag Pharmaceutical tablet capable of liberating one or more drugs at different release rates
US5602180A (en) * 1995-03-31 1997-02-11 World Health Group Method of administering EDTA complexes
SG80553A1 (en) * 1995-07-20 2001-05-22 Tanabe Seiyaku Co Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
FR2742659B1 (fr) * 1995-12-22 1998-03-13 Pf Medicament Procede de fabrication de minispheres matricielles a liberation prolongee
WO1999017751A1 (en) * 1997-10-03 1999-04-15 Smithkline Beecham Corporation Controlled release solid dosage forms of lithium carbonate
DE69919155T2 (de) * 1998-05-15 2005-08-04 Chugai Seiyaku K.K. Formulierungen zur mehrfachfreisetzung
US7604820B1 (en) * 1999-08-09 2009-10-20 Dainippon Sumitomo Pharma Co., Ltd. Solid preparation containing chitosan powder and process for producing the same
JP3893058B2 (ja) 1999-09-30 2007-03-14 ペンウェスト ファーマシューティカルズ カンパニー 高度に可溶性の薬物のための徐放性マトリックス系
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
WO2002069977A1 (en) 2001-03-01 2002-09-12 Hollis-Eden Pharmaceuticals, Inc. Use of certain steroids for treatment of blood cell deficiencies
US6720356B2 (en) * 2001-04-20 2004-04-13 Spencer Feldman Magnesium di-potassium EDTA complex and method of administration
US7323192B2 (en) * 2001-09-28 2008-01-29 Mcneil-Ppc, Inc. Immediate release tablet
WO2003026625A1 (en) 2001-09-28 2003-04-03 Mcneil-Ppc, Inc. Modified release dosage forms
US7838026B2 (en) 2001-09-28 2010-11-23 Mcneil-Ppc, Inc. Burst-release polymer composition and dosage forms comprising the same
US7122143B2 (en) 2001-09-28 2006-10-17 Mcneil-Ppc, Inc. Methods for manufacturing dosage forms
US6837696B2 (en) * 2001-09-28 2005-01-04 Mcneil-Ppc, Inc. Apparatus for manufacturing dosage forms
US20060013875A1 (en) * 2002-05-29 2006-01-19 Impax Laboratories, Inc. Combination immediate release controlled release levodopa/carbidopa dosage forms
US20030224045A1 (en) * 2002-05-29 2003-12-04 Chien-Hsuan Han Combination immediate release sustained release levodopa/carbidopa dosage forms
US20040166159A1 (en) * 2002-05-29 2004-08-26 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain an aromatic amino acid decarboxylase inhibitor and levodopa
US7094427B2 (en) * 2002-05-29 2006-08-22 Impax Laboratories, Inc. Combination immediate release controlled release levodopa/carbidopa dosage forms
US20090035260A1 (en) * 2002-07-29 2009-02-05 Therapicon Srl Enhanced nasal composition of active peptide
US7807197B2 (en) * 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
US20040228918A1 (en) * 2003-01-02 2004-11-18 Chih-Ming Chen Granule modulating hydrogel system
ITMI20040235A1 (it) * 2004-02-13 2004-05-13 Therapicon Srl Preparazione farmaceutica per il cavo orale
DE102004039196B4 (de) 2004-08-12 2008-07-31 Dr.Kamprad Kg Neue Formulierung für L-Tryptophan
AU2005330504B2 (en) 2004-09-29 2010-10-28 Harbor Biosciences, Inc. Steroid analogs and characterization and treatment methods
US8673352B2 (en) * 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
EP2836233A1 (de) 2012-04-13 2015-02-18 Nanoscape AG Formulierung mit verzögerter freisetzung
US10098845B2 (en) 2013-10-07 2018-10-16 Impax Laboratories, Llc Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
US10987313B2 (en) 2013-10-07 2021-04-27 Impax Laboratories, Llc Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
US11986449B2 (en) 2020-12-22 2024-05-21 Amneal Pharmaceuticals Llc Levodopa dosing regimen
CN117618376B (zh) * 2023-12-11 2024-08-13 江苏诺和必拓新药研发有限公司 一种尼可地尔膜控缓释片及其制备方法

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES300432A1 (es) * 1963-06-04 1964-11-16 Abbott Lab Procedimiento para producir una composición analgésica
US3577491A (en) * 1968-01-02 1971-05-04 Miles Lab Tableting
US3849558A (en) * 1969-06-03 1974-11-19 Sumitomo Chemical Co Pharmaceutical compositions having controlled gastro-intestinal absorption
US3608063A (en) * 1969-08-15 1971-09-21 Gilbert S Banker Molecular drug entrapment process and compositions
BE759520A (fr) * 1969-11-28 1971-04-30 Aspro Nicholas Ltd Compositions d'aspirine
US3903255A (en) * 1971-05-17 1975-09-02 Rohm & Haas Effervescent potassium chloride tablet
JPS5115094B2 (de) * 1972-11-01 1976-05-14
US3993999A (en) * 1975-05-16 1976-11-23 Texas Instruments Incorporated Amplitude modulation scanning antenna system
US4021546A (en) * 1976-03-08 1977-05-03 Interx Research Corporation Pro-drug forms of digoxin and method of preparing and using same
DE2656227C2 (de) * 1976-12-11 1985-07-04 Bayer Ag, 5090 Leverkusen Basisch alkylierte Diphenyldisulfid-2,2'-biscarbonsäureamide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
GB1576376A (en) * 1977-03-30 1980-10-08 Benzon As Alfred Multiple-unit drug dose
US4180559A (en) * 1978-01-05 1979-12-25 Richardson-Merrell Inc. Coated 1-(2-chlorodibenzo[b,f]oxepin-10-yl)-4-methylpiperazine compositions
DE2841170A1 (de) * 1978-09-21 1980-04-03 Pharmazeutische Praeparate Apo Hypnotikum
US4342764A (en) * 1979-05-29 1982-08-03 Ciba-Geigy Corporation Guanidine compounds, pharmaceutical compositions and use
US4406896A (en) * 1979-12-20 1983-09-27 Merck & Co., Inc. Adjuvants for rectal delivery of drug substances
DE3011327A1 (de) * 1980-03-24 1981-10-01 Basf Ag, 6700 Ludwigshafen 1-aroyl-2-phenylamino-2-imidazoline, ihre herstellung und verwendung
ZA823333B (de) * 1981-04-24 1983-11-14
IT1198386B (it) * 1982-07-06 1988-12-21 Lepetit Spa Un prodotto a rilascio protratto contenente il suloctidile
US4704284A (en) * 1982-08-12 1987-11-03 Pfizer Inc. Long-acting matrix tablet formulations
US4503031A (en) * 1982-12-17 1985-03-05 Glassman Jacob A Super-fast-starting-sustained release tablet
HU191542B (en) * 1983-04-08 1987-03-30 Boehringer Ingelheim Ltd Process for production of pastiles containing dipyridamel independent from ph with regulated output of the active substance
PH18946A (en) * 1983-04-21 1985-11-14 Elan Corp Plc Controlled absorption pharmaceutical composition
DE3315797A1 (de) * 1983-04-30 1984-10-31 Beiersdorf Ag, 2000 Hamburg Substituierte phenyl-2-(1h)-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
US4530920A (en) * 1983-11-07 1985-07-23 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH agonist
JPH0653658B2 (ja) * 1984-12-17 1994-07-20 中外製薬株式会社 安定な錠剤の製造法
FR2588559B1 (fr) * 1985-10-11 1988-03-11 Bp Chimie Sa Procede de polymerisation ou de copolymerisation d'alpha-olefines en presence d'un systeme catalytique ziegler-natta ameliore

Also Published As

Publication number Publication date
NO175763B (no) 1994-08-29
EP0386801A3 (en) 1990-11-07
CA1282327C (en) 1991-04-02
DK455286A (da) 1987-03-27
IE66255B1 (en) 1995-12-27
SG64993G (en) 1993-08-06
EP0386801B1 (de) 1994-07-20
IE81099B1 (en) 2000-03-08
DK455286D0 (da) 1986-09-24
AU587281B2 (en) 1989-08-10
DK170110B1 (da) 1995-05-29
DE3689983T2 (de) 1995-02-23
FI863889A0 (fi) 1986-09-26
AU6273086A (en) 1987-04-02
FI863889A (fi) 1987-03-27
DK108192A (da) 1992-08-31
DK166478B1 (da) 1993-06-01
DE3689983D1 (de) 1994-08-25
ATE108647T1 (de) 1994-08-15
FI86146B (fi) 1992-04-15
DK108192D0 (da) 1992-08-31
ES2001993A6 (es) 1988-07-01
NO863796L (no) 1987-03-27
EP0386801A2 (de) 1990-09-12
KR950010145B1 (ko) 1995-09-11
IE862468L (en) 1987-03-26
JPS62149630A (ja) 1987-07-03
DE3678661D1 (de) 1991-05-16
HK65393A (en) 1993-07-16
JPH0772142B2 (ja) 1995-08-02
FI86146C (fi) 1992-07-27
NO175763C (no) 1994-12-07
KR870002838A (ko) 1987-04-13
IE940953L (en) 1987-03-26
EP0218148B1 (de) 1991-04-10
NO863796D0 (no) 1986-09-24
EP0218148A1 (de) 1987-04-15
US5188840A (en) 1993-02-23

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time