ATE554397T1 - Verfahren zur stabilisierung von alpha-thrombin in einer thrombinhaltigen lösung - Google Patents
Verfahren zur stabilisierung von alpha-thrombin in einer thrombinhaltigen lösungInfo
- Publication number
- ATE554397T1 ATE554397T1 AT07849800T AT07849800T ATE554397T1 AT E554397 T1 ATE554397 T1 AT E554397T1 AT 07849800 T AT07849800 T AT 07849800T AT 07849800 T AT07849800 T AT 07849800T AT E554397 T1 ATE554397 T1 AT E554397T1
- Authority
- AT
- Austria
- Prior art keywords
- thrombin
- solution containing
- solution
- stabilizing
- stabilizing alpha
- Prior art date
Links
- 229960004072 thrombin Drugs 0.000 title abstract 9
- 108090000190 Thrombin Proteins 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- 230000000087 stabilizing effect Effects 0.000 title abstract 3
- 108010049003 Fibrinogen Proteins 0.000 abstract 1
- 102000008946 Fibrinogen Human genes 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 229940012952 fibrinogen Drugs 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006344121 | 2006-12-21 | ||
| PCT/JP2007/001367 WO2008075455A1 (ja) | 2006-12-21 | 2007-12-06 | トロンビン含有溶液中のα－トロンビンの安定化方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE554397T1 true ATE554397T1 (de) | 2012-05-15 |
Family
ID=39536094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07849800T ATE554397T1 (de) | 2006-12-21 | 2007-12-06 | Verfahren zur stabilisierung von alpha-thrombin in einer thrombinhaltigen lösung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8580532B2 (de) |
| EP (1) | EP2096440B1 (de) |
| JP (1) | JP5121725B2 (de) |
| CN (1) | CN101558310B (de) |
| AT (1) | ATE554397T1 (de) |
| ES (1) | ES2382758T3 (de) |
| WO (1) | WO2008075455A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10046081B2 (en) | 2008-04-11 | 2018-08-14 | The Henry M Jackson Foundation For The Advancement Of Military Medicine, Inc. | Electrospun dextran fibers and devices formed therefrom |
| US20160193381A1 (en) * | 2015-01-06 | 2016-07-07 | St. Teresa Medical, Inc. | Hemostatic products |
| EP3280444B1 (de) * | 2015-04-10 | 2024-05-08 | Adimab, LLC | Verfahren zur reinigung heterodimerer multispezifischer antikörper aus elterlichen homodimeren antikörperarten |
| CA3004734A1 (en) | 2015-11-12 | 2017-06-18 | St. Teresa Medical, Inc. | A method of sealing a durotomy |
| CN106337044B (zh) * | 2016-09-30 | 2018-08-31 | 迈克生物股份有限公司 | 凝血酶溶液 |
| CN106350501B (zh) * | 2016-09-30 | 2018-06-01 | 迈克生物股份有限公司 | 凝血酶溶液的稳定剂 |
| CN106350499B (zh) * | 2016-09-30 | 2018-07-10 | 迈克生物股份有限公司 | 凝血酶溶液的稳定剂 |
| CN106350500B (zh) * | 2016-09-30 | 2018-02-23 | 迈克生物股份有限公司 | 凝血酶溶液 |
| CN106480007B (zh) * | 2016-09-30 | 2018-02-23 | 迈克生物股份有限公司 | 凝血酶溶液的稳定剂 |
| JP6889535B2 (ja) * | 2016-10-05 | 2021-06-18 | デンカ株式会社 | 赤血球の凝集方法及び分離方法並びに赤血球凝集用試薬 |
| CN107942063A (zh) * | 2016-10-13 | 2018-04-20 | 北京众驰伟业科技发展有限公司 | 一种血浆纤维蛋白原的检测试剂、其检测方法及应用 |
| CN106645751B (zh) * | 2016-12-27 | 2018-08-03 | 北京赛科希德科技股份有限公司 | 一种纤维蛋白原含量检测试剂盒 |
| US10953128B2 (en) | 2017-11-02 | 2021-03-23 | St. Teresa Medical, Inc. | Fibrin sealant products |
| CN112578130A (zh) * | 2019-09-30 | 2021-03-30 | 积水医疗科技(苏州)有限公司 | 凝血酶溶液、试剂盒、凝血酶的稳定化方法、检测试剂以及凝血酶时间的测定方法 |
| CN118010469B (zh) * | 2024-04-08 | 2024-07-02 | 中国人民解放军军事科学院军事医学研究院 | 一种纤维蛋白原浓度定量检测稀释液及其制备方法与应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4696812A (en) * | 1985-10-28 | 1987-09-29 | Warner-Lambert Company | Thrombin preparations |
| JPS6440433A (en) | 1987-08-05 | 1989-02-10 | Green Cross Corp | Aqueous liquid composition of thrombin |
| DE60032001T2 (de) * | 1999-09-27 | 2007-05-31 | Sysmex Corp. | Verfahren zur stabilisierung von thrombin |
| DE10012732A1 (de) * | 2000-03-18 | 2001-09-20 | Aventis Behring Gmbh | Thrombin-Zubereitungen und Verfahren zu ihrer Herstellung |
| JP2004191367A (ja) | 2002-11-28 | 2004-07-08 | Sysmex Corp | トロンビン試薬及び検査試薬キット |
| ES2397234T3 (es) * | 2007-06-15 | 2013-03-05 | Zymogenetics, Inc. | Composiciones estabilizadas de trombina |
| AU2008296206A1 (en) * | 2007-09-05 | 2009-03-12 | Zymogenetics, Inc. | Mass spectrometry-based quantitative assay for determining abundance of molecular species in a composition |
-
2007
- 2007-12-06 AT AT07849800T patent/ATE554397T1/de active
- 2007-12-06 ES ES07849800T patent/ES2382758T3/es active Active
- 2007-12-06 WO PCT/JP2007/001367 patent/WO2008075455A1/ja not_active Ceased
- 2007-12-06 JP JP2008550039A patent/JP5121725B2/ja active Active
- 2007-12-06 CN CN200780046549.2A patent/CN101558310B/zh active Active
- 2007-12-06 US US12/519,191 patent/US8580532B2/en active Active
- 2007-12-06 EP EP07849800A patent/EP2096440B1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP5121725B2 (ja) | 2013-01-16 |
| CN101558310A (zh) | 2009-10-14 |
| EP2096440A4 (de) | 2010-03-24 |
| US8580532B2 (en) | 2013-11-12 |
| WO2008075455A1 (ja) | 2008-06-26 |
| JPWO2008075455A1 (ja) | 2010-04-08 |
| EP2096440A1 (de) | 2009-09-02 |
| EP2096440B1 (de) | 2012-04-18 |
| US20100047834A1 (en) | 2010-02-25 |
| ES2382758T3 (es) | 2012-06-13 |
| CN101558310B (zh) | 2013-05-08 |
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