ATE552833T1 - Methoxypolyethylenglykol-thioester-chelat und dessen verwendung - Google Patents
Methoxypolyethylenglykol-thioester-chelat und dessen verwendungInfo
- Publication number
- ATE552833T1 ATE552833T1 AT07750513T AT07750513T ATE552833T1 AT E552833 T1 ATE552833 T1 AT E552833T1 AT 07750513 T AT07750513 T AT 07750513T AT 07750513 T AT07750513 T AT 07750513T AT E552833 T1 ATE552833 T1 AT E552833T1
- Authority
- AT
- Austria
- Prior art keywords
- methoxypolyethylene glycol
- chelate
- glycol thioester
- mpdte
- patient
- Prior art date
Links
- -1 GLYCOL THIOESTER Chemical class 0.000 title abstract 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 title abstract 2
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 title abstract 2
- 239000013522 chelant Substances 0.000 title 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 abstract 1
- 230000030833 cell death Effects 0.000 abstract 1
- 230000004410 intraocular pressure Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960003330 pentetic acid Drugs 0.000 abstract 1
- 230000002207 retinal effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/28—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77287406P | 2006-02-14 | 2006-02-14 | |
| PCT/US2007/003682 WO2007095178A2 (en) | 2006-02-14 | 2007-02-14 | Methoxypolyethylene glycol thioester chelate and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE552833T1 true ATE552833T1 (de) | 2012-04-15 |
Family
ID=38372058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07750513T ATE552833T1 (de) | 2006-02-14 | 2007-02-14 | Methoxypolyethylenglykol-thioester-chelat und dessen verwendung |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US8008347B2 (enExample) |
| EP (2) | EP2428234A1 (enExample) |
| JP (2) | JP5138612B2 (enExample) |
| CN (1) | CN101394844A (enExample) |
| AT (1) | ATE552833T1 (enExample) |
| AU (1) | AU2007215211B2 (enExample) |
| CA (1) | CA2642453A1 (enExample) |
| WO (1) | WO2007095178A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5138612B2 (ja) * | 2006-02-14 | 2013-02-06 | イースタン バージニア メディカル スクール | メトキシポリエチレングリコールチオエステルキレートおよびその使用 |
| JP2010100615A (ja) * | 2008-09-25 | 2010-05-06 | Santen Pharmaceut Co Ltd | ポリアルキレングリコールを有効成分として含有する網膜疾患の予防又は治療剤 |
| TWI568453B (zh) * | 2011-11-22 | 2017-02-01 | 原創生醫股份有限公司 | 具有螯合型複合微胞之藥物載體及其應用 |
| JP6086576B2 (ja) * | 2012-04-24 | 2017-03-01 | 公立大学法人首都大学東京 | 抗酸化剤 |
| WO2018236221A2 (en) * | 2017-06-03 | 2018-12-27 | Can Holding B.V. | Neurodegenerative peptide deposit dissolution |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4352751A (en) * | 1979-09-10 | 1982-10-05 | Analytical Radiation Corporation | Species-linked diamine triacetic acids and their chelates |
| JP2722250B2 (ja) | 1989-05-30 | 1998-03-04 | 興和株式会社 | 新規なジアミン化合物及びこれを含有する脳機能障害改善剤 |
| JPH0680964A (ja) * | 1991-12-27 | 1994-03-22 | Sogo Yatsukou Kk | 活性酸素消去剤 |
| EP0955044B1 (en) * | 1995-06-26 | 2005-11-16 | Chelator LLC | Method of inhibiting bacterial or fungal growth using a complexing agent |
| AU7454796A (en) | 1995-10-20 | 1997-05-07 | Eastern Virginia Medical School | Chelate derivatives as protectors against tissue injury |
| US6020373A (en) * | 1995-10-20 | 2000-02-01 | Eastern Virginia Medical School | Chelate derivatives as protectors against tissue injury |
| WO2004058289A1 (en) * | 2002-12-20 | 2004-07-15 | Chakshu Research, Inc. | Ophthalmic formulation for the prevention and treatment of ocular conditions |
| JP5138612B2 (ja) * | 2006-02-14 | 2013-02-06 | イースタン バージニア メディカル スクール | メトキシポリエチレングリコールチオエステルキレートおよびその使用 |
-
2007
- 2007-02-14 JP JP2008555298A patent/JP5138612B2/ja not_active Expired - Fee Related
- 2007-02-14 AU AU2007215211A patent/AU2007215211B2/en not_active Ceased
- 2007-02-14 CN CNA200780007327XA patent/CN101394844A/zh active Pending
- 2007-02-14 US US12/279,521 patent/US8008347B2/en not_active Expired - Fee Related
- 2007-02-14 EP EP11181006A patent/EP2428234A1/en not_active Withdrawn
- 2007-02-14 EP EP07750513A patent/EP1986631B1/en not_active Not-in-force
- 2007-02-14 CA CA002642453A patent/CA2642453A1/en not_active Abandoned
- 2007-02-14 WO PCT/US2007/003682 patent/WO2007095178A2/en not_active Ceased
- 2007-02-14 AT AT07750513T patent/ATE552833T1/de active
- 2007-02-14 US US11/705,759 patent/US7388028B2/en not_active Expired - Fee Related
-
2011
- 2011-07-22 US US13/188,914 patent/US8796336B2/en not_active Expired - Fee Related
- 2011-08-16 JP JP2011177877A patent/JP2012031173A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1986631A2 (en) | 2008-11-05 |
| CA2642453A1 (en) | 2007-08-23 |
| EP1986631A4 (en) | 2010-10-27 |
| AU2007215211B2 (en) | 2010-08-26 |
| AU2007215211A1 (en) | 2007-08-23 |
| WO2007095178A3 (en) | 2008-04-17 |
| US7388028B2 (en) | 2008-06-17 |
| EP2428234A1 (en) | 2012-03-14 |
| WO2007095178A2 (en) | 2007-08-23 |
| US20090306205A1 (en) | 2009-12-10 |
| US20080039524A1 (en) | 2008-02-14 |
| US8796336B2 (en) | 2014-08-05 |
| JP2012031173A (ja) | 2012-02-16 |
| JP2009527474A (ja) | 2009-07-30 |
| US8008347B2 (en) | 2011-08-30 |
| CN101394844A (zh) | 2009-03-25 |
| JP5138612B2 (ja) | 2013-02-06 |
| EP1986631B1 (en) | 2012-04-11 |
| US20120016030A1 (en) | 2012-01-19 |
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