CY1111778T1 - Παραγωγα θειοξανθενιου ως μοναδικοι αντιμολυσματικοι παραγοντες για χρηση στην αντιμετωπιση των μολυσματικων ασθενειων - Google Patents

Παραγωγα θειοξανθενιου ως μοναδικοι αντιμολυσματικοι παραγοντες για χρηση στην αντιμετωπιση των μολυσματικων ασθενειων

Info

Publication number
CY1111778T1
CY1111778T1 CY20111100800T CY111100800T CY1111778T1 CY 1111778 T1 CY1111778 T1 CY 1111778T1 CY 20111100800 T CY20111100800 T CY 20111100800T CY 111100800 T CY111100800 T CY 111100800T CY 1111778 T1 CY1111778 T1 CY 1111778T1
Authority
CY
Cyprus
Prior art keywords
derivatives
treatment
diseases
pollutical
thioxanthenium
Prior art date
Application number
CY20111100800T
Other languages
English (en)
Inventor
Birgit Kjælgaard Giwercman
Original Assignee
Bkg Pharma Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bkg Pharma Aps filed Critical Bkg Pharma Aps
Publication of CY1111778T1 publication Critical patent/CY1111778T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Dairy Products (AREA)

Abstract

Η παρούσα εφεύρεση απευθύνεται στη χρήση ορισμένων παραγώγων θειοξανθενίου και παραγώγων φαινοθειαζίνης ως αντιμολυσματικών παραγόντων, ειδικότερα, για την αντιμετώπιση των μολυσματικών ασθενειών. Η εφεύρεση περαιτέρω αναφέρεται σε συνθέσεις που περιλαμβάνουν τους εν λόγω αντιμολυσματικούς παράγοντες.
CY20111100800T 2007-01-05 2011-08-22 Παραγωγα θειοξανθενιου ως μοναδικοι αντιμολυσματικοι παραγοντες για χρηση στην αντιμετωπιση των μολυσματικων ασθενειων CY1111778T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/DK2007/000006 WO2008080398A1 (en) 2007-01-05 2007-01-05 Anti - infective agents such as phenothiazine and thioxanthene derivates to treat infectious diseases
EP08700129A EP2114406B1 (en) 2007-01-05 2008-01-07 Thioxanthene derivates as sole anti-infective agents for use in the treatment of infectious diseases

Publications (1)

Publication Number Publication Date
CY1111778T1 true CY1111778T1 (el) 2015-10-07

Family

ID=37914358

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100800T CY1111778T1 (el) 2007-01-05 2011-08-22 Παραγωγα θειοξανθενιου ως μοναδικοι αντιμολυσματικοι παραγοντες για χρηση στην αντιμετωπιση των μολυσματικων ασθενειων

Country Status (18)

Country Link
US (1) US20100113430A1 (el)
EP (2) EP2301545A1 (el)
JP (2) JP5399921B2 (el)
CN (1) CN101594869B (el)
AT (1) ATE510540T1 (el)
AU (1) AU2008203743B2 (el)
CA (1) CA2673809C (el)
CY (1) CY1111778T1 (el)
DK (1) DK2114406T3 (el)
EA (1) EA016886B1 (el)
ES (1) ES2367151T3 (el)
HK (1) HK1139309A1 (el)
HR (1) HRP20110607T1 (el)
MX (1) MX2009007235A (el)
NZ (1) NZ577821A (el)
PL (1) PL2114406T3 (el)
PT (1) PT2114406E (el)
WO (2) WO2008080398A1 (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2009007235A (es) * 2007-01-05 2009-10-16 Bkg Pharma Aps "derivados de tioxanteno utiles para el tratamiento de enfermedades infecciosas.".
EP2246349A1 (en) * 2009-04-20 2010-11-03 BKG Pharma ApS Treatment of infectious diseases
CN103172591B (zh) * 2013-03-13 2014-07-30 陕西科技大学 含吩噻嗪基的Schiff碱类化合物及其制备方法和应用
CN103709122B (zh) * 2013-11-29 2016-05-25 四川大学 用于治疗的抗肿瘤和抗真菌化合物
RU2019101646A (ru) * 2016-06-23 2020-07-23 Биоимикс Аб Противоинфекционные гетероциклические соединения и варианты их применения
CN112353805A (zh) * 2020-11-17 2021-02-12 北京化工大学 氟哌噻吨在治疗和预防柯萨奇病毒感染中的应用

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE578983A (el) 1958-05-29
DE1210890B (de) 1960-03-07 1966-02-17 Smith & Kline & French Lab Verfahren zur Herstellung von Trifluormethyl-xanthen- oder thioxanthenderivaten
GB1453828A (en) * 1972-12-08 1976-10-27 Kefalas As Fluoro-substituted thiaxanthene derivatives
US4407800A (en) * 1981-11-02 1983-10-04 University Of Virginia Alumni Patents Foundation Protozoacidal activity of phenothiazines
AU625071B2 (en) * 1988-04-20 1992-07-02 Merrell Dow Pharmaceuticals Inc. N-alkylamino derivatives of aromatic, tricyclic compounds in the treatment of drug-resistant protozoal infections
US20020151543A1 (en) * 1998-05-28 2002-10-17 Sepracor Inc. Compositions and methods employing R (-) fluoxetine and other active ingredients
FR2813792B1 (fr) * 2000-09-12 2003-03-14 Inst Necker Moyens pour la regulation des defenses immunitaires
US6569853B1 (en) 2000-11-06 2003-05-27 Combinatorx, Incorporated Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders
AU2002325192B2 (en) 2001-07-06 2008-05-22 Veloxis Pharmaceuticals, Inc. Controlled agglomeration
US20030229082A1 (en) * 2002-01-16 2003-12-11 The Regents Of The University Of California Inhibition of RNA function
US20060193788A1 (en) * 2002-11-26 2006-08-31 Hale Ron L Acute treatment of headache with phenothiazine antipsychotics
AU2003205543A1 (en) 2003-01-14 2004-08-10 Lifecycle Pharma A/S Dry dispersions
US7429660B2 (en) * 2003-08-13 2008-09-30 Kudos Pharmaceuticals Limited ATM inhibitors
CN1976723B (zh) * 2004-04-30 2010-12-29 Bkg制药有限公司 制备治疗或预防感染性疾病的药物的用途
WO2006094207A2 (en) * 2005-03-03 2006-09-08 St. Jude Children's Research Hospital Substituted phenoxazines and acridones as inhibitors of akt
MX2009007235A (es) * 2007-01-05 2009-10-16 Bkg Pharma Aps "derivados de tioxanteno utiles para el tratamiento de enfermedades infecciosas.".
EP2246349A1 (en) * 2009-04-20 2010-11-03 BKG Pharma ApS Treatment of infectious diseases

Also Published As

Publication number Publication date
JP5399921B2 (ja) 2014-01-29
ATE510540T1 (de) 2011-06-15
JP2013173752A (ja) 2013-09-05
JP2010514814A (ja) 2010-05-06
CA2673809A1 (en) 2008-07-10
EP2114406A1 (en) 2009-11-11
NZ577821A (en) 2012-07-27
EP2114406B1 (en) 2011-05-25
PT2114406E (pt) 2011-08-25
WO2008080408A1 (en) 2008-07-10
HK1139309A1 (en) 2010-09-17
US20100113430A1 (en) 2010-05-06
EA200970663A1 (ru) 2009-12-30
AU2008203743B2 (en) 2012-07-12
AU2008203743A1 (en) 2008-07-10
EA016886B1 (ru) 2012-08-30
WO2008080398A1 (en) 2008-07-10
CN101594869B (zh) 2013-08-07
MX2009007235A (es) 2009-10-16
HRP20110607T1 (hr) 2011-09-30
DK2114406T3 (da) 2011-09-12
EP2301545A1 (en) 2011-03-30
PL2114406T3 (pl) 2011-10-31
CN101594869A (zh) 2009-12-02
ES2367151T3 (es) 2011-10-28
CA2673809C (en) 2013-08-13

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