CA2642453A1 - Methoxypolyethylene glycol thioester chelate and uses thereof - Google Patents

Methoxypolyethylene glycol thioester chelate and uses thereof Download PDF

Info

Publication number
CA2642453A1
CA2642453A1 CA002642453A CA2642453A CA2642453A1 CA 2642453 A1 CA2642453 A1 CA 2642453A1 CA 002642453 A CA002642453 A CA 002642453A CA 2642453 A CA2642453 A CA 2642453A CA 2642453 A1 CA2642453 A1 CA 2642453A1
Authority
CA
Canada
Prior art keywords
compound
pharmaceutically acceptable
patient
formula
free radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002642453A
Other languages
English (en)
French (fr)
Inventor
Karl A. Schellenberg
Frank A. Lattanzio
James Shaeffer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eastern Virginia Medical School
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2642453A1 publication Critical patent/CA2642453A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/20—Esters of monothiocarboxylic acids
    • C07C327/28—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Steroid Compounds (AREA)
CA002642453A 2006-02-14 2007-02-14 Methoxypolyethylene glycol thioester chelate and uses thereof Abandoned CA2642453A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77287406P 2006-02-14 2006-02-14
US60/772,874 2006-02-14
PCT/US2007/003682 WO2007095178A2 (en) 2006-02-14 2007-02-14 Methoxypolyethylene glycol thioester chelate and uses thereof

Publications (1)

Publication Number Publication Date
CA2642453A1 true CA2642453A1 (en) 2007-08-23

Family

ID=38372058

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002642453A Abandoned CA2642453A1 (en) 2006-02-14 2007-02-14 Methoxypolyethylene glycol thioester chelate and uses thereof

Country Status (8)

Country Link
US (3) US8008347B2 (enExample)
EP (2) EP2428234A1 (enExample)
JP (2) JP5138612B2 (enExample)
CN (1) CN101394844A (enExample)
AT (1) ATE552833T1 (enExample)
AU (1) AU2007215211B2 (enExample)
CA (1) CA2642453A1 (enExample)
WO (1) WO2007095178A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5138612B2 (ja) * 2006-02-14 2013-02-06 イースタン バージニア メディカル スクール メトキシポリエチレングリコールチオエステルキレートおよびその使用
JP2010100615A (ja) * 2008-09-25 2010-05-06 Santen Pharmaceut Co Ltd ポリアルキレングリコールを有効成分として含有する網膜疾患の予防又は治療剤
TWI568453B (zh) * 2011-11-22 2017-02-01 原創生醫股份有限公司 具有螯合型複合微胞之藥物載體及其應用
JP6086576B2 (ja) * 2012-04-24 2017-03-01 公立大学法人首都大学東京 抗酸化剤
WO2018236221A2 (en) * 2017-06-03 2018-12-27 Can Holding B.V. Neurodegenerative peptide deposit dissolution

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352751A (en) * 1979-09-10 1982-10-05 Analytical Radiation Corporation Species-linked diamine triacetic acids and their chelates
JP2722250B2 (ja) 1989-05-30 1998-03-04 興和株式会社 新規なジアミン化合物及びこれを含有する脳機能障害改善剤
JPH0680964A (ja) * 1991-12-27 1994-03-22 Sogo Yatsukou Kk 活性酸素消去剤
EP0955044B1 (en) * 1995-06-26 2005-11-16 Chelator LLC Method of inhibiting bacterial or fungal growth using a complexing agent
AU7454796A (en) 1995-10-20 1997-05-07 Eastern Virginia Medical School Chelate derivatives as protectors against tissue injury
US6020373A (en) * 1995-10-20 2000-02-01 Eastern Virginia Medical School Chelate derivatives as protectors against tissue injury
WO2004058289A1 (en) * 2002-12-20 2004-07-15 Chakshu Research, Inc. Ophthalmic formulation for the prevention and treatment of ocular conditions
JP5138612B2 (ja) * 2006-02-14 2013-02-06 イースタン バージニア メディカル スクール メトキシポリエチレングリコールチオエステルキレートおよびその使用

Also Published As

Publication number Publication date
EP1986631A2 (en) 2008-11-05
EP1986631A4 (en) 2010-10-27
AU2007215211B2 (en) 2010-08-26
AU2007215211A1 (en) 2007-08-23
WO2007095178A3 (en) 2008-04-17
US7388028B2 (en) 2008-06-17
EP2428234A1 (en) 2012-03-14
WO2007095178A2 (en) 2007-08-23
US20090306205A1 (en) 2009-12-10
US20080039524A1 (en) 2008-02-14
US8796336B2 (en) 2014-08-05
JP2012031173A (ja) 2012-02-16
JP2009527474A (ja) 2009-07-30
ATE552833T1 (de) 2012-04-15
US8008347B2 (en) 2011-08-30
CN101394844A (zh) 2009-03-25
JP5138612B2 (ja) 2013-02-06
EP1986631B1 (en) 2012-04-11
US20120016030A1 (en) 2012-01-19

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20151216