ATE551073T1 - Markierte hgf-bindende peptide für bildgebung - Google Patents
Markierte hgf-bindende peptide für bildgebungInfo
- Publication number
- ATE551073T1 ATE551073T1 AT08750628T AT08750628T ATE551073T1 AT E551073 T1 ATE551073 T1 AT E551073T1 AT 08750628 T AT08750628 T AT 08750628T AT 08750628 T AT08750628 T AT 08750628T AT E551073 T1 ATE551073 T1 AT E551073T1
- Authority
- AT
- Austria
- Prior art keywords
- imaging
- binding peptides
- labelled
- monitoring
- vivo
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 238000003384 imaging method Methods 0.000 title abstract 2
- 206010009944 Colon cancer Diseases 0.000 abstract 2
- 208000001333 Colorectal Neoplasms Diseases 0.000 abstract 2
- 238000012544 monitoring process Methods 0.000 abstract 2
- 206010061818 Disease progression Diseases 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 230000005750 disease progression Effects 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000011503 in vivo imaging Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 238000012634 optical imaging Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000006853 reporter group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0056—Peptides, proteins, polyamino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4842—Monitoring progression or stage of a disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Solid State Image Pick-Up Elements (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0709441A GB0709441D0 (en) | 2007-05-16 | 2007-05-16 | Peptide imaging agents |
| GB0715682A GB0715682D0 (en) | 2007-08-13 | 2007-08-13 | Peptide imaging agents |
| PCT/GB2008/001696 WO2008139207A2 (en) | 2007-05-16 | 2008-05-16 | Labelled hgf binding peptides for imaging |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE551073T1 true ATE551073T1 (de) | 2012-04-15 |
Family
ID=39743846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08750628T ATE551073T1 (de) | 2007-05-16 | 2008-05-16 | Markierte hgf-bindende peptide für bildgebung |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8529874B2 (enExample) |
| EP (1) | EP2146749B1 (enExample) |
| JP (1) | JP2010526859A (enExample) |
| KR (2) | KR20150017387A (enExample) |
| CN (1) | CN101848734B (enExample) |
| AT (1) | ATE551073T1 (enExample) |
| AU (1) | AU2008249821B2 (enExample) |
| BR (1) | BRPI0811210B1 (enExample) |
| CA (1) | CA2685553C (enExample) |
| ES (1) | ES2385066T3 (enExample) |
| IL (1) | IL201778A0 (enExample) |
| MX (1) | MX2009012386A (enExample) |
| NZ (1) | NZ581160A (enExample) |
| PL (1) | PL2146749T3 (enExample) |
| RU (2) | RU2473361C9 (enExample) |
| WO (1) | WO2008139207A2 (enExample) |
| ZA (1) | ZA200908016B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008139206A2 (en) * | 2007-05-16 | 2008-11-20 | Ge Healthcare As | Optical imaging agents |
| GB0718967D0 (en) * | 2007-09-28 | 2007-11-07 | Ge Healthcare Ltd | Peptide imaging agents |
| GB0918321D0 (en) | 2009-10-20 | 2009-12-02 | Ge Healthcare As | Cyclic peptide synthesis |
| GB201010878D0 (en) | 2010-06-29 | 2010-08-11 | Ge Healthcare As | Dye compositiion and dye syntheses |
| US20130095040A1 (en) * | 2010-06-29 | 2013-04-18 | Ge Healthcare As | Dye compositions and dye syntheses |
| GB201013808D0 (en) * | 2010-08-18 | 2010-09-29 | Ge Healthcare Ltd | Peptide radiotracer compositions |
| EP2625281A2 (en) * | 2010-10-06 | 2013-08-14 | EMD Millipore Corporation | Cyanine compounds, conjugates and method of use |
| RU2013140291A (ru) | 2011-03-01 | 2015-04-10 | ДжиИ ХЕЛТКЕР ЛИМИТЕД | Меченые радиоактивной меткой аналоги октреотата в качестве рет-индикаторов |
| GB201103696D0 (en) | 2011-03-04 | 2011-04-20 | Ge Healthcare Ltd | Technetium labelled peptides |
| DE102011118029A1 (de) | 2011-06-20 | 2012-12-20 | Universität Leipzig | Modifizierte antibiotische Peptide mit variabler systemischer Freisetzung |
| GB201116733D0 (en) | 2011-09-28 | 2011-11-09 | Ge Healthcare As | Peptide margin imaging agents |
| GB201116862D0 (en) | 2011-09-30 | 2011-11-09 | Ge Healthcare As | Infusion imaging method |
| GB201121914D0 (en) | 2011-12-20 | 2012-02-01 | Ge Healthcare Ltd | Method for patient selection |
| WO2014152718A1 (en) * | 2013-03-15 | 2014-09-25 | Arizona Board Of Regents, For And On Behalf Of Arizona State University | Saccharide conjugates |
| GB201314936D0 (en) | 2013-08-21 | 2013-10-02 | Ge Healthcare Ltd | Radiolabelling method |
| GB201322456D0 (en) | 2013-12-18 | 2014-02-05 | Ge Healthcare Ltd | Radiotracer compositions and methods |
| CN105111773B (zh) * | 2015-08-19 | 2017-06-27 | 大连理工大学 | 一类氨基菁类荧光染料及其制备方法和应用 |
| GB201804835D0 (en) * | 2018-03-26 | 2018-05-09 | Ge Healthcare As | Formulation and method of preparation |
| CN112129736B (zh) * | 2020-09-22 | 2022-08-02 | 四川大学华西医院 | 粘蛋白和循环肿瘤细胞的均相可视化/荧光poct检测方法 |
| WO2022258455A1 (en) * | 2021-06-07 | 2022-12-15 | Surgvision Gmbh | Stable liquid phantom for near-infrared fluorescence verification |
| TW202404643A (zh) | 2022-04-20 | 2024-02-01 | 大陸商同宜醫藥（蘇州）有限公司 | 化合物及用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7615646B2 (en) * | 2002-05-10 | 2009-11-10 | Carnegie Mellon University | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups |
| GB0223249D0 (en) * | 2002-10-08 | 2002-11-13 | Amersham Plc | Improved imaging agents |
| WO2004075032A2 (en) * | 2003-02-19 | 2004-09-02 | Sicel Technologies Inc. | In vivo fluorescence sensors, systems, and related methods operating in conjunction with fluorescent analytes |
| SI2949658T1 (sl) * | 2003-03-03 | 2018-10-30 | Dyax Corp. | Peptidi, ki specifično vežejo HGF receptor (cMet) in njihove uporabe |
| NO20034350D0 (no) * | 2003-09-29 | 2003-09-29 | Amersham Health As | Optisk avbilding av kolorektal kreft |
| ATE522580T1 (de) * | 2003-10-31 | 2011-09-15 | Ge Healthcare Ltd | Cyaninfarbstoffe als markieragenzien |
| US7785566B2 (en) | 2003-11-06 | 2010-08-31 | Ge Healthcare, Inc. | Pharmaceutical compounds |
| NO20035682D0 (no) | 2003-12-18 | 2003-12-18 | Amersham Health As | Optisk avbildning av ösofagkreft og Barretts ösofag |
| EP1833512A1 (en) * | 2005-01-06 | 2007-09-19 | GE Healthcare AS | Optical imaging |
| US8053415B2 (en) * | 2005-01-21 | 2011-11-08 | Washington University In St. Louis | Compounds having RD targeting motifs |
| GB0502277D0 (en) | 2005-02-04 | 2005-03-09 | Amersham Plc | Novel imaging agents |
| ATE502048T1 (de) | 2005-04-22 | 2011-04-15 | Univ Washington | Fluoreszentes chlorotoxinkonjugat und verfahren zur intraoperativen sichtbarmachung von krebs |
| NO20053354D0 (no) | 2005-07-11 | 2005-07-11 | Amersham Health As | Optical imaging contrast agent. |
-
2008
- 2008-05-16 WO PCT/GB2008/001696 patent/WO2008139207A2/en not_active Ceased
- 2008-05-16 EP EP08750628A patent/EP2146749B1/en active Active
- 2008-05-16 AT AT08750628T patent/ATE551073T1/de active
- 2008-05-16 RU RU2009140475/10A patent/RU2473361C9/ru active
- 2008-05-16 JP JP2010507982A patent/JP2010526859A/ja active Pending
- 2008-05-16 CN CN2008800242291A patent/CN101848734B/zh not_active Expired - Fee Related
- 2008-05-16 RU RU2009140478/15A patent/RU2475266C2/ru not_active IP Right Cessation
- 2008-05-16 ES ES08750628T patent/ES2385066T3/es active Active
- 2008-05-16 AU AU2008249821A patent/AU2008249821B2/en not_active Expired - Fee Related
- 2008-05-16 US US12/600,265 patent/US8529874B2/en not_active Expired - Fee Related
- 2008-05-16 KR KR1020157002055A patent/KR20150017387A/ko not_active Ceased
- 2008-05-16 CA CA2685553A patent/CA2685553C/en active Active
- 2008-05-16 NZ NZ581160A patent/NZ581160A/en not_active IP Right Cessation
- 2008-05-16 MX MX2009012386A patent/MX2009012386A/es active IP Right Grant
- 2008-05-16 BR BRPI0811210-0A patent/BRPI0811210B1/pt not_active IP Right Cessation
- 2008-05-16 PL PL08750628T patent/PL2146749T3/pl unknown
- 2008-05-16 KR KR1020097023746A patent/KR101578225B1/ko not_active Expired - Fee Related
-
2009
- 2009-10-27 IL IL201778A patent/IL201778A0/en unknown
- 2009-11-13 ZA ZA2009/08016A patent/ZA200908016B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2685553C (en) | 2017-03-28 |
| ES2385066T3 (es) | 2012-07-17 |
| PL2146749T3 (pl) | 2012-09-28 |
| US20100150843A1 (en) | 2010-06-17 |
| AU2008249821A1 (en) | 2008-11-20 |
| BRPI0811210A2 (pt) | 2014-11-11 |
| EP2146749A2 (en) | 2010-01-27 |
| RU2009140478A (ru) | 2011-06-27 |
| NZ581160A (en) | 2012-05-25 |
| KR101578225B1 (ko) | 2015-12-17 |
| KR20100016543A (ko) | 2010-02-12 |
| CN101848734A (zh) | 2010-09-29 |
| WO2008139207A3 (en) | 2009-02-26 |
| RU2009140475A (ru) | 2011-06-27 |
| MX2009012386A (es) | 2009-12-03 |
| CA2685553A1 (en) | 2008-11-20 |
| AU2008249821B2 (en) | 2013-08-22 |
| ZA200908016B (en) | 2012-04-25 |
| IL201778A0 (en) | 2010-06-16 |
| RU2473361C9 (ru) | 2013-06-20 |
| WO2008139207A2 (en) | 2008-11-20 |
| BRPI0811210B1 (pt) | 2021-11-09 |
| RU2475266C2 (ru) | 2013-02-20 |
| KR20150017387A (ko) | 2015-02-16 |
| US8529874B2 (en) | 2013-09-10 |
| RU2473361C2 (ru) | 2013-01-27 |
| EP2146749B1 (en) | 2012-03-28 |
| JP2010526859A (ja) | 2010-08-05 |
| CN101848734B (zh) | 2013-08-28 |
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