ATE548347T1 - Trägerampholyte mit hohem ph-wert-bereich - Google Patents
Trägerampholyte mit hohem ph-wert-bereichInfo
- Publication number
- ATE548347T1 ATE548347T1 AT05705627T AT05705627T ATE548347T1 AT E548347 T1 ATE548347 T1 AT E548347T1 AT 05705627 T AT05705627 T AT 05705627T AT 05705627 T AT05705627 T AT 05705627T AT E548347 T1 ATE548347 T1 AT E548347T1
- Authority
- AT
- Austria
- Prior art keywords
- range
- carrier ampholytes
- ampholytes
- carrier
- substances
- Prior art date
Links
- 239000000959 ampholyte mixture Substances 0.000 title abstract 2
- 229920000768 polyamine Polymers 0.000 abstract 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N guanidine group Chemical group NC(=N)N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 1
- 238000001155 isoelectric focusing Methods 0.000 abstract 1
- 229920001281 polyalkylene Polymers 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44795—Isoelectric focusing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/12—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44747—Composition of gel or of carrier mixture
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/763,405 US7022214B2 (en) | 2004-01-21 | 2004-01-21 | Carrier ampholytes of high pH range |
| PCT/US2005/001061 WO2005072121A2 (en) | 2004-01-21 | 2005-01-12 | Carrier ampholytes of high ph range |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE548347T1 true ATE548347T1 (de) | 2012-03-15 |
Family
ID=34750409
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05705627T ATE548347T1 (de) | 2004-01-21 | 2005-01-12 | Trägerampholyte mit hohem ph-wert-bereich |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7022214B2 (de) |
| EP (1) | EP1718960B1 (de) |
| AT (1) | ATE548347T1 (de) |
| DE (1) | DE05705627T1 (de) |
| WO (1) | WO2005072121A2 (de) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10209217B2 (en) | 2015-11-30 | 2019-02-19 | Intabio, Inc. | Devices and methods for sample characterization |
| US10514360B1 (en) | 2018-05-31 | 2019-12-24 | Intabio, Inc. | Software for microfluidic systems interfacing with mass spectrometry |
| US10591488B2 (en) | 2018-01-29 | 2020-03-17 | Intabio, Inc. | Devices, methods and kits for sample characterization |
| US10870113B1 (en) | 2019-08-12 | 2020-12-22 | Intabio, Inc. | Isoelectric focusing devices and fixtures |
| US12594557B2 (en) | 2019-08-12 | 2026-04-07 | Intabio, Llc | Isoelectric focusing devices and fixtures |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020142304A1 (en) * | 2001-03-09 | 2002-10-03 | Anderson Daniel G. | Uses and methods of making microarrays of polymeric biomaterials |
| WO2006138380A2 (en) | 2005-06-15 | 2006-12-28 | Massachusetts Institute Of Technology | Amine-containing lipids and uses thereof |
| EP3269395A1 (de) | 2008-11-07 | 2018-01-17 | Massachusetts Institute Of Technology | Aminoalkohol-lipoide und verwendungen davon |
| NZ619320A (en) | 2009-04-22 | 2015-08-28 | Mercator Medsystems Inc | Use of guanethidine for treating hypertension by local vascular delivery |
| EP3318248B1 (de) | 2009-12-01 | 2019-04-10 | Translate Bio, Inc. | Ausgabe von mrna zur vermehrung von proteinen und enzymen bei humangenetischen erkrankungen |
| US9193827B2 (en) | 2010-08-26 | 2015-11-24 | Massachusetts Institute Of Technology | Poly(beta-amino alcohols), their preparation, and uses thereof |
| EP2691443B1 (de) | 2011-03-28 | 2021-02-17 | Massachusetts Institute of Technology | Konjugierte lipomers und ihre verwendung |
| RU2013154295A (ru) | 2011-06-08 | 2015-07-20 | Шир Хьюман Дженетик Терапис, Инк. | КОМПОЗИЦИИ ЛИПИДНЫХ НАНОЧАСТИЦ И СПОСОБЫ ДЛЯ ДОСТАВКИ мРНК |
| AU2012325801B2 (en) | 2011-10-19 | 2016-05-12 | Mercator Medsystems, Inc. | Localized modulation of tissues and cells to enhance therapeutic effects including renal denervation |
| CA2861402C (en) * | 2012-01-30 | 2021-10-12 | Guy Casy | Stabilized aqueous antibody compositions |
| US20140374260A1 (en) * | 2012-02-07 | 2014-12-25 | Sharp Kabushiki Kaisha | Two-dimensional electrophoresis kit, method for manufacturing two-dimensional electrophoresis kit, two-dimensional electrophoresis method, and two-dimensional electrophoresis chip |
| WO2013185067A1 (en) | 2012-06-08 | 2013-12-12 | Shire Human Genetic Therapies, Inc. | Nuclease resistant polynucleotides and uses thereof |
| WO2014028487A1 (en) | 2012-08-13 | 2014-02-20 | Massachusetts Institute Of Technology | Amine-containing lipidoids and uses thereof |
| JP6586075B2 (ja) | 2013-03-14 | 2019-10-02 | トランスレイト バイオ， インコーポレイテッド | メッセンジャーｒｎａの精製方法 |
| RS57739B1 (sr) | 2013-03-14 | 2018-12-31 | Translate Bio Inc | Kompozicije cftr irnk i postupci i upotrebe u vezi sa njima |
| WO2014179562A1 (en) | 2013-05-01 | 2014-11-06 | Massachusetts Institute Of Technology | 1,3,5-triazinane-2,4,6-trione derivatives and uses thereof |
| ES3032935T3 (en) | 2013-10-22 | 2025-07-29 | Translate Bio Inc | Lipid formulations for delivery of messenger rna |
| JP6506749B2 (ja) | 2013-10-22 | 2019-04-24 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | フェニルケトン尿症のためのｍＲＮＡ療法 |
| CN106413811A (zh) | 2013-10-22 | 2017-02-15 | 夏尔人类遗传性治疗公司 | 精氨基琥珀酸合成酶缺乏症的mrna疗法 |
| US9850269B2 (en) | 2014-04-25 | 2017-12-26 | Translate Bio, Inc. | Methods for purification of messenger RNA |
| JP6557722B2 (ja) | 2014-05-30 | 2019-08-07 | シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド | 核酸の送達のための生分解性脂質 |
| KR102559979B1 (ko) | 2014-06-24 | 2023-07-25 | 샤이어 휴먼 지네틱 테라피즈 인크. | 핵산의 전달용 입체화학적으로 풍부한 조성물 |
| US9840479B2 (en) | 2014-07-02 | 2017-12-12 | Massachusetts Institute Of Technology | Polyamine-fatty acid derived lipidoids and uses thereof |
| EA201991747A1 (ru) | 2017-02-27 | 2020-06-04 | Транслейт Био, Инк. | НОВАЯ КОДОН-ОПТИМИЗИРОВАННАЯ мРНК CFTR |
| MX2019013752A (es) | 2017-05-16 | 2020-07-20 | Translate Bio Inc | Tratamiento de la fibrosis quística mediante el suministro de arnm que codifica cftr optimizado en codones. |
| KR102950141B1 (ko) | 2018-08-24 | 2026-04-07 | 트랜슬레이트 바이오 인코포레이티드 | 전령 rna의 정제 방법 |
| WO2020106946A1 (en) | 2018-11-21 | 2020-05-28 | Translate Bio, Inc. | TREATMENT OF CYSTIC FIBROSIS BY DELIVERY OF NEBULIZED mRNA ENCODING CFTR |
| EP4031662A1 (de) | 2019-09-20 | 2022-07-27 | Translate Bio, Inc. | Mrna-codierendes technisches cftr |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1114155A (en) * | 1964-08-24 | 1968-05-15 | Evans Medical Ltd | Guanidino derivatives |
| DE2137617C3 (de) | 1971-07-28 | 1979-01-04 | Grubhofer, Nikolaus, Dr., 6900 Heidelberg | Verfahren zur Herstellung wäßriger Ampholytlösungen oder deren Gemischen |
| DE2230743B2 (de) | 1972-06-23 | 1980-08-07 | Nikolaus Dr. 6900 Heidelberg Grubhofer | Verfahren zur Herstellung-wäBriger Ampholytlösungen |
| DE2656801C2 (de) | 1976-12-15 | 1983-11-17 | Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Verfahren zur Herstellung von Trägerampholyten für die isoelektrische Fokussierung von hochmolekularen amphoteren Stoffen |
| GB8713854D0 (en) | 1987-06-13 | 1987-07-15 | Kozulic B | Poly-n-acryloyl-tris(hydroxymethyl)aminomethane gels |
| US5242947A (en) * | 1988-02-10 | 1993-09-07 | New York University | Use of polyamines as ionic-channel regulating agents |
| US5173160A (en) | 1991-02-27 | 1992-12-22 | Board Of Regents, The University Of Texas System | Analysis of carrier ampholytes using immobilized ph gradients |
| US5322906A (en) | 1991-02-27 | 1994-06-21 | Board Of Regents, The University Of Texas System | Synthesis of complex polyamines for ampholyte production |
| US6072075A (en) | 1997-05-22 | 2000-06-06 | The Regents Of The University Of California | Guanidinylation reagents |
-
2004
- 2004-01-21 US US10/763,405 patent/US7022214B2/en not_active Expired - Lifetime
-
2005
- 2005-01-12 DE DE05705627T patent/DE05705627T1/de active Pending
- 2005-01-12 AT AT05705627T patent/ATE548347T1/de active
- 2005-01-12 EP EP05705627A patent/EP1718960B1/de not_active Expired - Lifetime
- 2005-01-12 WO PCT/US2005/001061 patent/WO2005072121A2/en not_active Ceased
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10209217B2 (en) | 2015-11-30 | 2019-02-19 | Intabio, Inc. | Devices and methods for sample characterization |
| US10401324B2 (en) | 2015-11-30 | 2019-09-03 | Intabio, Inc. | Devices and methods for sample characterization |
| US10591488B2 (en) | 2018-01-29 | 2020-03-17 | Intabio, Inc. | Devices, methods and kits for sample characterization |
| US10514360B1 (en) | 2018-05-31 | 2019-12-24 | Intabio, Inc. | Software for microfluidic systems interfacing with mass spectrometry |
| US10870113B1 (en) | 2019-08-12 | 2020-12-22 | Intabio, Inc. | Isoelectric focusing devices and fixtures |
| US11224875B2 (en) | 2019-08-12 | 2022-01-18 | Intabio, Llc | Isoelectric focusing devices and fixtures |
| US11285484B2 (en) | 2019-08-12 | 2022-03-29 | Intabio, Llc | Multichannel isoelectric focusing devices and high voltage power supplies |
| US12594557B2 (en) | 2019-08-12 | 2026-04-07 | Intabio, Llc | Isoelectric focusing devices and fixtures |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1718960B1 (de) | 2012-03-07 |
| DE05705627T1 (de) | 2007-05-03 |
| EP1718960A2 (de) | 2006-11-08 |
| US7022214B2 (en) | 2006-04-04 |
| WO2005072121A3 (en) | 2006-04-27 |
| EP1718960A4 (de) | 2007-10-31 |
| WO2005072121A2 (en) | 2005-08-11 |
| US20050155862A1 (en) | 2005-07-21 |
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