ATE540947T1 - Neue tricyclische angiotensin-ii-agonisten - Google Patents

Neue tricyclische angiotensin-ii-agonisten

Info

Publication number
ATE540947T1
ATE540947T1 AT06726719T AT06726719T ATE540947T1 AT E540947 T1 ATE540947 T1 AT E540947T1 AT 06726719 T AT06726719 T AT 06726719T AT 06726719 T AT06726719 T AT 06726719T AT E540947 T1 ATE540947 T1 AT E540947T1
Authority
AT
Austria
Prior art keywords
agonists
new tricyclic
angiotensin
compounds
tricyclic angiotensin
Prior art date
Application number
AT06726719T
Other languages
German (de)
English (en)
Inventor
Mathias Alterman
Xiongyu Wu
A Hallberg
Original Assignee
Vicore Pharma Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vicore Pharma Ab filed Critical Vicore Pharma Ab
Application granted granted Critical
Publication of ATE540947T1 publication Critical patent/ATE540947T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/08—Vasodilators for multiple indications
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/12—Antihypertensives

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  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nutrition Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
AT06726719T 2005-04-12 2006-04-12 Neue tricyclische angiotensin-ii-agonisten ATE540947T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67025105P 2005-04-12 2005-04-12
PCT/GB2006/001319 WO2006109048A1 (en) 2005-04-12 2006-04-12 New tricyclic angiotensin ii agonists

Publications (1)

Publication Number Publication Date
ATE540947T1 true ATE540947T1 (de) 2012-01-15

Family

ID=36616540

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06726719T ATE540947T1 (de) 2005-04-12 2006-04-12 Neue tricyclische angiotensin-ii-agonisten

Country Status (12)

Country Link
US (1) US8080571B2 (https=)
EP (1) EP1869023B1 (https=)
JP (2) JP5202301B2 (https=)
KR (1) KR101429484B1 (https=)
CN (1) CN101193886B (https=)
AT (1) ATE540947T1 (https=)
AU (1) AU2006235698B2 (https=)
CA (1) CA2604797C (https=)
DK (1) DK1869023T3 (https=)
ES (1) ES2395194T3 (https=)
MX (1) MX2007012634A (https=)
WO (1) WO2006109048A1 (https=)

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AU2006235698B2 (en) * 2005-04-12 2012-03-29 Vicore Pharma Ab New tricyclic angiotensin II agonists
TW200840566A (en) * 2006-12-22 2008-10-16 Esteve Labor Dr Heterocyclyl-substituted-ethylamino-phenyl derivatives, their preparation and use as medicaments
EP1935886A1 (en) * 2006-12-22 2008-06-25 Laboratorios del Dr. Esteve S.A. Heterocyclyl-substituted-ethylamino-phenyl derivatives, their preparation and use as medicaments
EP2832357A1 (en) 2013-07-29 2015-02-04 Charité - Universitätsmedizin Berlin Selective AT2 receptor agonists for use in treatment of cachexia
EP3820498A1 (en) 2018-06-14 2021-05-19 University College Cork-National University of Ireland Cork Peptide for disease treatment
GB201913603D0 (en) 2019-09-20 2019-11-06 Vicore Pharma Ab New compounds
KR20230004501A (ko) * 2020-03-19 2023-01-06 바이코어 파마 아베 안지오텐신 ⅱ와 관련된 질병, 장애, 또는 병태의 치료 및/또는 예방에 유용한 신규 화합물
GB202007122D0 (en) * 2020-05-14 2020-07-01 Vicore Pharma Ab New process
GB202013721D0 (en) * 2020-09-01 2020-10-14 Vicore Pharma Ab New compounds
CA3247073A1 (en) * 2022-04-06 2025-02-03 Wuhan Humanwell Innovative Drug Research and Development Center Limited Company AT2R AGONIST
CN116355025B (zh) * 2023-04-03 2025-03-28 天津医科大学 一种HO-1i-Pt(IV)配合物和自组装纳米粒的制备方法及其在肿瘤药物中的应用
CN119504723A (zh) * 2023-08-25 2025-02-25 武汉人福创新药物研发中心有限公司 作为at2r激动剂的噻吩磺酰基氨基甲酸酯
TW202508554A (zh) * 2023-08-25 2025-03-01 大陸商武漢人福創新藥物研發中心有限公司 一種作為ａｔ２ｒ促效劑的噻吩磺醯基氨基甲酸酯及其用途
WO2025146172A1 (zh) * 2024-01-03 2025-07-10 武汉人福创新药物研发中心有限公司 一种并环类化合物作为at2r激动剂
WO2025252142A1 (zh) * 2024-06-07 2025-12-11 江苏柯菲平医药股份有限公司 一种血管紧张素ii型2受体激动剂及其用途

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JP4385113B2 (ja) * 2002-09-18 2009-12-16 株式会社ポーラファルマ 新規ビフェニルイミダゾピリジン誘導体及びそれを有効成分とする医薬
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AU2003286251A1 (en) 2002-11-21 2004-06-15 Vicore Pharma Ab New bicyclic angiotensin ii agonists
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AU2006235698B2 (en) * 2005-04-12 2012-03-29 Vicore Pharma Ab New tricyclic angiotensin II agonists

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MX2007012634A (es) 2008-01-11
ES2395194T3 (es) 2013-02-11
JP2013040208A (ja) 2013-02-28
JP2008535898A (ja) 2008-09-04
JP5718301B2 (ja) 2015-05-13
US8080571B2 (en) 2011-12-20
EP1869023A1 (en) 2007-12-26
KR101429484B1 (ko) 2014-08-13
AU2006235698B2 (en) 2012-03-29
DK1869023T3 (da) 2012-04-10
EP1869023B1 (en) 2012-01-11
CN101193886B (zh) 2014-08-27
WO2006109048A1 (en) 2006-10-19
AU2006235698A1 (en) 2006-10-19
CN101193886A (zh) 2008-06-04
CA2604797C (en) 2013-05-28
CA2604797A1 (en) 2006-10-19
JP5202301B2 (ja) 2013-06-05
US20090042931A1 (en) 2009-02-12
KR20080009275A (ko) 2008-01-28

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