ATE539170T1 - Abschätzung und verringerung des risikos von graft-versus-host-reaktion - Google Patents
Abschätzung und verringerung des risikos von graft-versus-host-reaktionInfo
- Publication number
- ATE539170T1 ATE539170T1 AT07719640T AT07719640T ATE539170T1 AT E539170 T1 ATE539170 T1 AT E539170T1 AT 07719640 T AT07719640 T AT 07719640T AT 07719640 T AT07719640 T AT 07719640T AT E539170 T1 ATE539170 T1 AT E539170T1
- Authority
- AT
- Austria
- Prior art keywords
- assessing
- versus host
- graft versus
- risk
- reducing
- Prior art date
Links
- 208000024908 graft versus host disease Diseases 0.000 title abstract 3
- 208000009329 Graft vs Host Disease Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000011223 gene expression profiling Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
- G01N2800/245—Transplantation related diseases, e.g. graft versus host disease
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74576106P | 2006-04-27 | 2006-04-27 | |
| PCT/CA2007/000714 WO2007124578A1 (en) | 2006-04-27 | 2007-04-27 | Assessment and reduction of risk of graft-versus-host disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE539170T1 true ATE539170T1 (de) | 2012-01-15 |
Family
ID=38655008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07719640T ATE539170T1 (de) | 2006-04-27 | 2007-04-27 | Abschätzung und verringerung des risikos von graft-versus-host-reaktion |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US7763425B2 (de) |
| EP (1) | EP2021534B1 (de) |
| JP (1) | JP5171812B2 (de) |
| AT (1) | ATE539170T1 (de) |
| CA (1) | CA2650507A1 (de) |
| WO (1) | WO2007124578A1 (de) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2553551C (en) | 2004-01-21 | 2020-12-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for determining a graft tolerant phenotype in a subject |
| USRE46843E1 (en) | 2005-03-14 | 2018-05-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for evaluating graft survival in a solid organ transplant recipient |
| EP2604703B1 (de) | 2005-03-14 | 2017-02-01 | The Board of Trustees of the Leland Stanford Junior University | Verfahren zur Bewertung der Haltbarkeit eines Pfropfs im Körper eines Empfängers fester Organtransplantate |
| WO2009075811A1 (en) * | 2007-12-07 | 2009-06-18 | Tufts Medical Center, Inc. | Compositions and methods for immortalizing cells and screening for anti-cancer agents |
| BRPI0907440A2 (pt) * | 2008-01-22 | 2016-11-01 | Veridex Llc | estadiamento molecular de câncer de cólon em estágio ii e iii prognóstico |
| WO2010021696A1 (en) | 2008-08-18 | 2010-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for determining a graft tolerant phenotype in a subject |
| ES2492498T3 (es) | 2009-01-15 | 2014-09-09 | The Board Of Trustees Of The Leland Stanford Junior University | Panel de biomarcadores para el diagnóstico y la predicción de rechazo de injerto |
| US20120077689A1 (en) * | 2009-02-17 | 2012-03-29 | Sarwal Minnie M | Compartment-Specific Non-HLA Targets for Diagnosis and Prediction of Graft Outcome |
| GB0917457D0 (en) * | 2009-10-06 | 2009-11-18 | Glaxosmithkline Biolog Sa | Method |
| US9290813B2 (en) | 2009-12-02 | 2016-03-22 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarkers for determining an allograft tolerant phenotype |
| IT1397083B1 (it) * | 2009-12-04 | 2012-12-28 | Biouniversa Srl | Marcatore biochimico serico |
| CA2794255C (en) | 2010-03-25 | 2020-01-14 | The Board Of Trustees Of The Leland Stanford Junior University | Protein and gene biomarkers for rejection of organ transplants |
| US20120277999A1 (en) * | 2010-10-29 | 2012-11-01 | Pbd Biodiagnostics, Llc | Methods, kits and arrays for screening for, predicting and identifying donors for hematopoietic cell transplantation, and predicting risk of hematopoietic cell transplant (hct) to induce graft vs. host disease (gvhd) |
| KR20130132904A (ko) * | 2010-12-06 | 2013-12-05 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 인간 모노클로날 항체 |
| US8440797B2 (en) | 2010-12-06 | 2013-05-14 | Dainippon Sumitomo Pharma Co., Ltd. | Human monoclonal antibody |
| GB201021149D0 (en) * | 2010-12-14 | 2011-01-26 | Georg August Uni Gottingen Stiftung Offentlichen Rechts | Use of a skin explant assay for mRNA expression analysis for the identification of new genes and drug targets associated with graft versus host disease |
| WO2012139051A2 (en) | 2011-04-06 | 2012-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Autoantibody biomarkers for iga nephropathy |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| EP3269802B1 (de) * | 2011-09-30 | 2019-10-23 | Bluebird Bio, Inc. | Verbindungen zur verbesserten viralen transduktion |
| JP5904801B2 (ja) * | 2012-01-17 | 2016-04-20 | シスメックス株式会社 | 制御性ｔ細胞への分化誘導能の予測方法及びその方法に用いられるバイオマーカー、並びにそれらの利用 |
| CN104736724A (zh) * | 2012-10-05 | 2015-06-24 | 日立化成株式会社 | 尿液外泌小体mRNA和使用其检测糖尿病型肾病的方法 |
| JP6297676B2 (ja) | 2013-05-06 | 2018-03-20 | 日立化成株式会社 | 標的分子を捕捉するためのデバイス及び方法 |
| US20160169890A1 (en) * | 2013-05-20 | 2016-06-16 | The Trustees Of Columbia University In The City Of New York | Tracking donor-reactive tcr as a biomarker in transplantation |
| US10726941B2 (en) | 2014-05-07 | 2020-07-28 | Pirche Ag | Methods and systems for predicting alloreactivity in transplantation |
| US10266895B2 (en) | 2014-11-05 | 2019-04-23 | Hitachi Chemical Company Ltd. | Exosomes and microvesicles in intestinal luminal fluids and stool and use of same for the assessment of inflammatory bowel disease |
| US10370719B2 (en) | 2014-11-12 | 2019-08-06 | Hitachi Chemical Co., Ltd. | Method and device for diagnosing organ injury |
| US9563744B1 (en) * | 2014-12-03 | 2017-02-07 | Biodesix, Inc. | Method of predicting development and severity of graft-versus-host disease |
| CN104878099B (zh) * | 2015-05-15 | 2018-02-16 | 西北农林科技大学 | 山羊atbf1基因单核苷酸多态性的检测方法及其应用 |
| US11028443B2 (en) | 2015-08-31 | 2021-06-08 | Showa Denko Materials Co., Ltd. | Molecular methods for assessing urothelial disease |
| ES2992295T3 (es) | 2016-02-12 | 2024-12-11 | Bluebird Bio Inc | Composiciones potenciadoras de Vcn y métodos de uso de las mismas |
| PL3589754T3 (pl) | 2017-03-01 | 2023-10-09 | F. Hoffmann-La Roche Ag | Sposoby diagnostyczne i terapeutyczne w chorobach nowotworowych |
| AU2018301716B2 (en) * | 2017-07-14 | 2024-06-13 | The Regents Of The University Of California | Novel methods of predicting transplant rejection risk |
| JPWO2020158832A1 (de) * | 2019-01-30 | 2020-08-06 | ||
| WO2020237219A1 (en) * | 2019-05-23 | 2020-11-26 | Rocket Pharmaceuticals, Ltd. | Gene therapy vectors for infantile malignant osteopetrosis |
| AU2023258039A1 (en) * | 2022-04-22 | 2024-11-21 | Spacecraft Seven, Llc | B-cell lymphoma 2–associated anthanogene 3 (bag3) gene therapy using aav vector |
| WO2024151826A1 (en) * | 2023-01-12 | 2024-07-18 | Jasper Therapeutics, Inc. | Methods for the prevention and treatment of gvhd |
| WO2025259362A1 (en) * | 2024-06-12 | 2025-12-18 | The Board Of Trustees Of The Leland Stanford Junior University | Enhancements for proximal signaling car activation |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL155450A0 (en) | 2000-10-20 | 2003-11-23 | Expression Diagnostics Inc | Leukocyte expression profiling |
| US7235358B2 (en) | 2001-06-08 | 2007-06-26 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing and monitoring transplant rejection |
| JP2005536212A (ja) * | 2002-08-22 | 2005-12-02 | ノバルティス アクチエンゲゼルシャフト | 慢性拒絶反応の診断法 |
| EP1694860A2 (de) * | 2003-12-03 | 2006-08-30 | Novartis AG | Biomarker für die transplantatabstossung |
| WO2005074540A2 (en) | 2004-01-30 | 2005-08-18 | University Of Pennsylvania | Novel predictors of transplant rejection determined by peripheral blood gene-expression profiling |
-
2007
- 2007-04-27 WO PCT/CA2007/000714 patent/WO2007124578A1/en not_active Ceased
- 2007-04-27 US US11/741,492 patent/US7763425B2/en not_active Expired - Fee Related
- 2007-04-27 AT AT07719640T patent/ATE539170T1/de active
- 2007-04-27 CA CA002650507A patent/CA2650507A1/en not_active Abandoned
- 2007-04-27 JP JP2009506882A patent/JP5171812B2/ja not_active Expired - Fee Related
- 2007-04-27 EP EP07719640A patent/EP2021534B1/de not_active Not-in-force
-
2010
- 2010-06-11 US US12/814,271 patent/US20100248254A1/en not_active Abandoned
-
2012
- 2012-11-20 US US13/682,303 patent/US9102981B2/en not_active Expired - Fee Related
-
2015
- 2015-06-30 US US14/755,956 patent/US20150337374A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2021534B1 (de) | 2011-12-28 |
| EP2021534A4 (de) | 2009-11-11 |
| US7763425B2 (en) | 2010-07-27 |
| JP2009538599A (ja) | 2009-11-12 |
| JP5171812B2 (ja) | 2013-03-27 |
| US20100248254A1 (en) | 2010-09-30 |
| US20130324427A1 (en) | 2013-12-05 |
| US9102981B2 (en) | 2015-08-11 |
| US20070264272A1 (en) | 2007-11-15 |
| EP2021534A1 (de) | 2009-02-11 |
| CA2650507A1 (en) | 2007-11-08 |
| WO2007124578A1 (en) | 2007-11-08 |
| US20150337374A1 (en) | 2015-11-26 |
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