ATE533473T1 - Neue klasse von surfuctantähnlichen materialien mit vitamin-e-tpgs und wasserlöslichem polymer - Google Patents
Neue klasse von surfuctantähnlichen materialien mit vitamin-e-tpgs und wasserlöslichem polymerInfo
- Publication number
- ATE533473T1 ATE533473T1 AT05813897T AT05813897T ATE533473T1 AT E533473 T1 ATE533473 T1 AT E533473T1 AT 05813897 T AT05813897 T AT 05813897T AT 05813897 T AT05813897 T AT 05813897T AT E533473 T1 ATE533473 T1 AT E533473T1
- Authority
- AT
- Austria
- Prior art keywords
- surfuct
- tpgs
- vitamin
- materials
- water soluble
- Prior art date
Links
- 239000000463 material Substances 0.000 title abstract 2
- AOBORMOPSGHCAX-UHFFFAOYSA-N Tocophersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-UHFFFAOYSA-N 0.000 title 1
- 229920003169 water-soluble polymer Polymers 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61271604P | 2004-09-24 | 2004-09-24 | |
| PCT/US2005/033324 WO2006036614A2 (en) | 2004-09-24 | 2005-09-16 | A new class of surfactant-like materials comprising vitamin e tpgs and a water soluble polymer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE533473T1 true ATE533473T1 (de) | 2011-12-15 |
Family
ID=36119387
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05813897T ATE533473T1 (de) | 2004-09-24 | 2005-09-16 | Neue klasse von surfuctantähnlichen materialien mit vitamin-e-tpgs und wasserlöslichem polymer |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20060068007A1 (enExample) |
| EP (1) | EP1799194B1 (enExample) |
| JP (1) | JP4977611B2 (enExample) |
| AT (1) | ATE533473T1 (enExample) |
| CA (1) | CA2578356C (enExample) |
| WO (1) | WO2006036614A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20090094815A (ko) * | 2006-11-09 | 2009-09-08 | 애보트 게엠베하 운트 콤파니 카게 | 티로신 키나아제 억제제의 경구 투여를 위한 약제 투여형 |
| US20100016449A1 (en) * | 2006-12-21 | 2010-01-21 | Boehringer Ingelheim International Gmbh | Formulations with Improved Bioavailability |
| WO2008093358A2 (en) * | 2007-01-29 | 2008-08-07 | Sun Pharmaceutical Industries Limited | Aqueous topical solution containing olopatadine |
| JP5668476B2 (ja) | 2007-10-08 | 2015-02-12 | オーリニア・ファーマシューティカルズ・インコーポレイテッドAurinia Pharmaceuticals Inc. | カルシニューリン阻害剤またはmTOR阻害剤を含む眼科用組成物 |
| JP5222550B2 (ja) * | 2007-12-27 | 2013-06-26 | 財團法人工業技術研究院 | 徐放性組成物およびその製造方法 |
| US9161943B2 (en) | 2007-12-31 | 2015-10-20 | Industrial Technology Research Institute | Sustained release composition and manufacturing method thereof |
| AR071375A1 (es) | 2008-04-22 | 2010-06-16 | Solvay Pharm Gmbh | Formulaciones para ingredientes farmaceuticos activos de permeabilidad deficiente, proceso de preparacion y producto |
| UY32099A (es) * | 2008-09-11 | 2010-04-30 | Enanta Pharm Inc | Inhibidores macrocíclicos de serina proteasas de hepatitis c |
| AR075180A1 (es) * | 2009-01-29 | 2011-03-16 | Novartis Ag | Formulaciones orales solidas de una pirido-pirimidinona |
| MX338355B (es) | 2009-06-09 | 2016-04-13 | Aurinia Pharmaceuticals Inc | Sistemas de suministro de farmaco topico para uso oftalmico. |
| WO2010150144A2 (en) | 2009-06-25 | 2010-12-29 | Wockhardt Research Centre | Low dose pharmaceutical compositions of celecoxib |
| CN103118681B (zh) * | 2010-03-10 | 2015-02-18 | 艾伯维巴哈马有限公司 | 固体组合物 |
| JP2014502620A (ja) | 2010-12-30 | 2014-02-03 | エナンタ ファーマシューティカルズ インコーポレイテッド | 大環状c型肝炎セリンプロテアーゼ阻害剤 |
| WO2012092411A2 (en) | 2010-12-30 | 2012-07-05 | Enanta Pharmaceuticals, Inc. | Phenanthridine macrocyclic hepatitis c serine protease inhibitors |
| US10201584B1 (en) | 2011-05-17 | 2019-02-12 | Abbvie Inc. | Compositions and methods for treating HCV |
| ITRM20120331A1 (it) | 2012-07-12 | 2014-01-13 | Guidotti & C Spa Labor | Composizioni pediatriche orali liquide contenenti nepadutant. |
| EP2900219B1 (en) * | 2012-09-27 | 2016-07-06 | Basf Se | A storage-stable dust-free homogeneous particulate formulation comprising at least one water-soluble vitamin e-derivative and at least one hydrophilic polymer |
| US9789063B2 (en) * | 2012-09-27 | 2017-10-17 | Basf Se | Storage-stable dust-free homogeneous particulate formulation |
| EP3089757A1 (en) | 2014-01-03 | 2016-11-09 | AbbVie Inc. | Solid antiviral dosage forms |
| US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
| CN108659214A (zh) * | 2018-05-21 | 2018-10-16 | 上海联陆实业股份有限公司 | 无溶剂合成水溶性维生素e聚乙二醇琥珀酸酯的制备方法 |
| EP4282475A3 (en) * | 2019-12-20 | 2024-02-28 | Intervet International B.V. | A pyrazole pharmaceutical composition |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9409778D0 (en) * | 1994-05-16 | 1994-07-06 | Dumex Ltd As | Compositions |
| US5558876A (en) * | 1995-03-29 | 1996-09-24 | Alcon Laboratories, Inc. | Topical ophthalmic acidic drug formulations |
| MY126358A (en) * | 1996-03-22 | 2006-09-29 | Glaxo Group Ltd | Compositions comprising vx478 and a water soluble tocopherol derivative such as vitamin e-tpgs |
| US5696101A (en) | 1996-04-16 | 1997-12-09 | Eastman Chemical Company | Oxidized cellulose and vitamin E blend for topical hemostatic applications |
| US5891469A (en) * | 1997-04-02 | 1999-04-06 | Pharmos Corporation | Solid Coprecipitates for enhanced bioavailability of lipophilic substances |
| CA2264718C (en) * | 1996-09-01 | 2006-05-30 | Pharmos Corporation | Solid coprecipitates for enhanced bioavailability of lipophilic substances |
| US5891845A (en) | 1997-11-21 | 1999-04-06 | Fuisz Technologies Ltd. | Drug delivery systems utilizing liquid crystal structures |
| US6280770B1 (en) | 1998-08-13 | 2001-08-28 | Cima Labs Inc. | Microemulsions as solid dosage forms for oral administration |
| US6331581B1 (en) * | 1998-12-24 | 2001-12-18 | Kansai Paint Co., Ltd. | Method for color matching of powder coating composition and process for the preparation thereof |
| DE19913606A1 (de) * | 1999-03-25 | 2000-09-28 | Basf Ag | Pulverförmige Solubilisationshilfsstoffe für feste pharmazeutische Darreichungsformen |
| UA74546C2 (en) * | 1999-04-06 | 2006-01-16 | Boehringer Ingelheim Ca Ltd | Macrocyclic peptides having activity relative to hepatitis c virus, a pharmaceutical composition and use of the pharmaceutical composition |
| US6608027B1 (en) | 1999-04-06 | 2003-08-19 | Boehringer Ingelheim (Canada) Ltd | Macrocyclic peptides active against the hepatitis C virus |
| US6416793B1 (en) * | 2000-07-11 | 2002-07-09 | Bioresponse, L.L.C. | Formulations and use of controlled-release indole alkaloids |
| DE10046541A1 (de) * | 2000-09-19 | 2002-03-28 | Knoll Ag | Mechanisch stabile darreichungsformen, enthaltend Ubichinone |
| ES2259079T3 (es) | 2001-01-19 | 2006-09-16 | Smithkline Beecham Corporation | Inhibidores de la actividad cinasa del receptor tie2 para tratar enfermedades angiogenicas. |
| US7172770B2 (en) | 2001-02-19 | 2007-02-06 | Board Of Regents, The University Of Texas System | Mesoporous compositions for use in drug delivery |
| AR033711A1 (es) * | 2001-05-09 | 2004-01-07 | Novartis Ag | Composiciones farmaceuticas |
| JP2003252750A (ja) * | 2002-02-26 | 2003-09-10 | ▲寛▼治 ▲高▼田 | 水溶性の難・低吸収性薬物のバイオアベイラビリティ改善技術 |
-
2005
- 2005-09-16 CA CA2578356A patent/CA2578356C/en not_active Expired - Fee Related
- 2005-09-16 US US11/228,123 patent/US20060068007A1/en not_active Abandoned
- 2005-09-16 JP JP2007533565A patent/JP4977611B2/ja not_active Expired - Fee Related
- 2005-09-16 WO PCT/US2005/033324 patent/WO2006036614A2/en not_active Ceased
- 2005-09-16 AT AT05813897T patent/ATE533473T1/de active
- 2005-09-16 EP EP05813897A patent/EP1799194B1/en not_active Revoked
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006036614A2 (en) | 2006-04-06 |
| JP4977611B2 (ja) | 2012-07-18 |
| WO2006036614A3 (en) | 2006-12-14 |
| EP1799194B1 (en) | 2011-11-16 |
| CA2578356A1 (en) | 2006-04-06 |
| JP2008514607A (ja) | 2008-05-08 |
| US20060068007A1 (en) | 2006-03-30 |
| CA2578356C (en) | 2013-05-28 |
| EP1799194A2 (en) | 2007-06-27 |
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