ATE522202T1 - Verfahren zur herstellung von sprühgetrockneten formulierungen von tmc125 - Google Patents

Verfahren zur herstellung von sprühgetrockneten formulierungen von tmc125

Info

Publication number
ATE522202T1
ATE522202T1 AT07729974T AT07729974T ATE522202T1 AT E522202 T1 ATE522202 T1 AT E522202T1 AT 07729974 T AT07729974 T AT 07729974T AT 07729974 T AT07729974 T AT 07729974T AT E522202 T1 ATE522202 T1 AT E522202T1
Authority
AT
Austria
Prior art keywords
tmc125
spray dried
dried formulations
producing spray
producing
Prior art date
Application number
AT07729974T
Other languages
English (en)
Inventor
Filip Rene Irene Kiekens
Jody Firmin Marceline Voorspoels
Lieven Elvire Colette Baert
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37179187&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE522202(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Application granted granted Critical
Publication of ATE522202T1 publication Critical patent/ATE522202T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT07729974T 2006-06-06 2007-06-06 Verfahren zur herstellung von sprühgetrockneten formulierungen von tmc125 ATE522202T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06115029 2006-06-06
PCT/EP2007/055607 WO2007141308A1 (en) 2006-06-06 2007-06-06 Process for preparing spray dried formulations of tmc125

Publications (1)

Publication Number Publication Date
ATE522202T1 true ATE522202T1 (de) 2011-09-15

Family

ID=37179187

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07729974T ATE522202T1 (de) 2006-06-06 2007-06-06 Verfahren zur herstellung von sprühgetrockneten formulierungen von tmc125

Country Status (27)

Country Link
US (2) US20090197903A1 (de)
EP (1) EP2029110B1 (de)
JP (1) JP5089685B2 (de)
KR (1) KR101179905B1 (de)
CN (1) CN101453989B (de)
AT (1) ATE522202T1 (de)
AU (1) AU2007255418C1 (de)
BR (1) BRPI0712346B8 (de)
CA (1) CA2651665C (de)
CY (1) CY1112154T1 (de)
DK (1) DK2029110T3 (de)
EC (1) ECSP088938A (de)
ES (1) ES2372983T3 (de)
HK (1) HK1129579A1 (de)
HR (1) HRP20110883T1 (de)
IL (1) IL195710A (de)
ME (1) ME01305B (de)
MX (1) MX2008015686A (de)
NO (1) NO343652B1 (de)
NZ (1) NZ572702A (de)
PL (1) PL2029110T3 (de)
PT (1) PT2029110E (de)
RS (1) RS52053B (de)
RU (1) RU2406502C2 (de)
SI (1) SI2029110T1 (de)
WO (1) WO2007141308A1 (de)
ZA (1) ZA200810345B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR065720A1 (es) 2007-03-14 2009-06-24 Tibotec Pharm Ltd Polvos para reconstitucion que comprenden rilpivirina dispersos en ciertos polimeros. uso. proceso.
US9050326B2 (en) 2008-04-02 2015-06-09 Astellas Pharma Inc. Amido derivatives-contained pharmaceutical composition
EP2306980A2 (de) * 2008-06-30 2011-04-13 Tibotec Pharmaceuticals Rekonstitutionspulver
WO2013109354A2 (en) * 2011-12-07 2013-07-25 Texas Southern University Etravirine formulations and uses thereof
CN104684545B (zh) * 2012-09-27 2018-04-03 巴斯夫欧洲公司 包含至少一种水溶性维生素e衍生物和至少一种亲水聚合物的储存稳定的无粉尘均质颗粒状配制剂
JP2021523976A (ja) * 2018-05-11 2021-09-09 サムヤン コーポレイション 固体分散体、その製造方法、それを用いる鎖延長ポリウレタン及びそれを含むエポキシ樹脂組成物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2920956B2 (ja) * 1989-10-06 1999-07-19 藤沢薬品工業株式会社 ニルバジピン含有持続性錠剤
US6395303B1 (en) 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
JPH107558A (ja) * 1996-06-19 1998-01-13 Eisai Co Ltd 溶解性改善製剤
HU230394B1 (hu) 1998-11-10 2016-04-28 Janssen Pharmaceutica N.V. HIV-vírus szaporodását gátló pirimidin-származékok
ATE400252T1 (de) * 1999-02-10 2008-07-15 Pfizer Prod Inc Pharmazeutische feste dispersionen
BRPI0014271B1 (pt) * 1999-09-24 2021-06-22 Janssen Pharmaceutica N.V. Partícula consistindo em uma dispersão de sólidos, uso da dita partícula, dispersão de sólidos, forma de dosagem farmacêutica, bem como processos de preparação de dita partícula, dispersão e forma de dosagem
DE19945982A1 (de) 1999-09-24 2001-03-29 Knoll Ag Geschwindigkeitsbestimmte Partikel
US6531158B1 (en) * 2000-08-09 2003-03-11 Impax Laboratories, Inc. Drug delivery system for enhanced bioavailability of hydrophobic active ingredients
KR100758045B1 (ko) * 2002-02-01 2007-09-11 화이자 프로덕츠 인크. 압력 노즐을 이용하여 균질한 분무 건조된 비결정질 고체약물 분산제를 제조하는 방법
AU2002350719A1 (en) * 2002-11-29 2004-06-23 Janssen Pharmaceutica N.V. Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
AU2003298010A1 (en) * 2002-12-19 2004-07-29 Pharmacia Corporation Non-hygroscopic formulation comprising a hydroscopic drug
US20060172010A1 (en) * 2003-07-17 2006-08-03 Gael Lamoureux Process for preparing particles containing an antiviral
CA2547404A1 (en) * 2003-12-09 2005-06-23 Pfizer Inc. Compositions comprising an hiv protease inhibitor

Also Published As

Publication number Publication date
ME01305B (me) 2012-04-30
AU2007255418A1 (en) 2007-12-13
EP2029110A1 (de) 2009-03-04
NO343652B1 (no) 2019-04-29
MX2008015686A (es) 2009-01-12
PT2029110E (pt) 2011-11-23
BRPI0712346B8 (pt) 2021-05-25
US20120208834A1 (en) 2012-08-16
RS52053B (en) 2012-04-30
IL195710A (en) 2014-02-27
NZ572702A (en) 2011-09-30
US9603803B2 (en) 2017-03-28
US20090197903A1 (en) 2009-08-06
JP5089685B2 (ja) 2012-12-05
KR101179905B1 (ko) 2012-09-07
EP2029110B1 (de) 2011-08-31
CY1112154T1 (el) 2015-12-09
CN101453989B (zh) 2012-06-13
CA2651665C (en) 2010-04-27
KR20090024131A (ko) 2009-03-06
HK1129579A1 (en) 2009-12-04
IL195710A0 (en) 2009-09-01
SI2029110T1 (sl) 2012-01-31
NO20090061L (no) 2009-01-06
HRP20110883T1 (hr) 2012-01-31
CA2651665A1 (en) 2007-12-13
DK2029110T3 (da) 2011-12-19
JP2009539804A (ja) 2009-11-19
ZA200810345B (en) 2012-05-30
ES2372983T3 (es) 2012-01-30
PL2029110T3 (pl) 2012-03-30
AU2007255418B2 (en) 2010-12-23
AU2007255418C1 (en) 2011-08-18
CN101453989A (zh) 2009-06-10
BRPI0712346A2 (pt) 2012-07-17
WO2007141308A1 (en) 2007-12-13
RU2406502C2 (ru) 2010-12-20
BRPI0712346B1 (pt) 2020-09-29
RU2008152411A (ru) 2010-07-20
ECSP088938A (es) 2009-01-30

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