ATE521629T1 - Matrixmetalloproteinase-11-impfstoff - Google Patents

Matrixmetalloproteinase-11-impfstoff

Info

Publication number
ATE521629T1
ATE521629T1 AT06792355T AT06792355T ATE521629T1 AT E521629 T1 ATE521629 T1 AT E521629T1 AT 06792355 T AT06792355 T AT 06792355T AT 06792355 T AT06792355 T AT 06792355T AT E521629 T1 ATE521629 T1 AT E521629T1
Authority
AT
Austria
Prior art keywords
mmp
compositions
terminus
linked
immunoenhancing element
Prior art date
Application number
AT06792355T
Other languages
German (de)
English (en)
Inventor
Luigi Aurisicchio
Monica Nicola La
Gennaro Ciliberto
Domenico Lazzaro
Federica Mori
Daniela Peruzzi
Original Assignee
Angeletti P Ist Richerche Bio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeletti P Ist Richerche Bio filed Critical Angeletti P Ist Richerche Bio
Application granted granted Critical
Publication of ATE521629T1 publication Critical patent/ATE521629T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6402Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
    • C12N9/6405Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
    • C12N9/6416Metalloendopeptidases (3.4.24)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT06792355T 2005-10-07 2006-10-03 Matrixmetalloproteinase-11-impfstoff ATE521629T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72449805P 2005-10-07 2005-10-07
PCT/EP2006/009536 WO2007042169A2 (en) 2005-10-07 2006-10-03 Matrix metalloproteinase 11 vaccine

Publications (1)

Publication Number Publication Date
ATE521629T1 true ATE521629T1 (de) 2011-09-15

Family

ID=37451271

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06792355T ATE521629T1 (de) 2005-10-07 2006-10-03 Matrixmetalloproteinase-11-impfstoff

Country Status (9)

Country Link
US (2) US8106176B2 (https=)
EP (1) EP1934246B8 (https=)
JP (1) JP5361386B2 (https=)
CN (1) CN101365715B (https=)
AT (1) ATE521629T1 (https=)
AU (1) AU2006301582B2 (https=)
CA (1) CA2623531C (https=)
ES (1) ES2370040T3 (https=)
WO (1) WO2007042169A2 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8216997B2 (en) 2008-08-14 2012-07-10 Acceleron Pharma, Inc. Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
TW201803586A (zh) 2008-08-14 2018-02-01 艾瑟勒朗法瑪公司 使用gdf阱以增加紅血球水平
EP2568044B1 (en) * 2008-09-29 2015-04-08 The Trustees of The University of Pennsylvania Tumor vascular marker-targeted vaccines
KR20120049214A (ko) 2009-06-08 2012-05-16 악셀레론 파마 인코포레이티드 발열성 지방세포를 증가시키는 방법
AU2010282361B2 (en) * 2009-08-13 2015-03-19 Acceleron Pharma Inc. Combined use of GDF traps and erythropoietin receptor activators to increase red blood cell levels
CN107028886A (zh) 2009-11-04 2017-08-11 不列颠哥伦比亚大学 含有核酸的脂质粒子及相关的方法
WO2013059922A1 (en) 2011-10-25 2013-05-02 The University Of British Columbia Limit size lipid nanoparticles and related methods
CN105143456A (zh) 2013-03-15 2015-12-09 不列颠哥伦比亚大学 用于转染的脂质纳米粒子和相关方法
LT3388075T (lt) 2015-03-27 2023-11-10 Immatics Biotechnologies Gmbh Nauji peptidai ir peptidų deriniai, skirti naudoti imunoterapijai prieš įvairius navikus (seq id 25 - mrax5-003)
GB201505305D0 (en) 2015-03-27 2015-05-13 Immatics Biotechnologies Gmbh Novel Peptides and combination of peptides for use in immunotherapy against various tumors
CN110418648B (zh) * 2017-02-22 2023-09-08 丁恩雨 一种编码人GM-CSF与多串连表位融合的mRNA癌症疫苗
US20220362402A1 (en) * 2019-10-08 2022-11-17 Exhaura, Ltd. Compositions and methods for ocular therapy
US20240199725A1 (en) 2021-04-16 2024-06-20 Korea University Research And Business Foundation Human antibody targeting covid-19 virus
GB202117583D0 (en) * 2021-12-06 2022-01-19 Cambridge Entpr Ltd Protein expression
CN116590263A (zh) * 2023-07-02 2023-08-15 广州庆毅生物医药科技有限公司 一种重组蛋白、单克隆抗体及其检测试剂盒和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78775A (en) * 1985-05-15 1992-06-21 Biotech Australia Pty Ltd Oral vaccines
GB9112553D0 (en) 1991-06-11 1991-07-31 Wellcome Found Fusion proteins
US5786464C1 (en) 1994-09-19 2012-04-24 Gen Hospital Corp Overexpression of mammalian and viral proteins
NZ332954A (en) * 1996-05-23 2000-07-28 Xoma Corp Use of BPI protein products to treat humans with hemorrhage due to trauma
US6114148C1 (en) * 1996-09-20 2012-05-01 Gen Hospital Corp High level expression of proteins
BR0010077A (pt) 1999-04-26 2002-01-15 K U Leuven Res & Dev Universit Gene sintético para expressão de uma proteìna retroviral ativa em eucariotas
CA2385172A1 (en) * 1999-10-08 2001-04-19 Active Biotech Ab Ab5 toxin b subunit mutants with altered chemical conjugation characteristics
GB9930768D0 (en) * 1999-12-29 2000-02-16 Pfizer Ltd Composition
JP2004508064A (ja) 2000-09-15 2004-03-18 メルク エンド カムパニー インコーポレーテッド コドン最適化hiv1−gag、pol、nefおよび修飾体を発現する増強された第1世代アデノウイルスワクチン
US20040110152A1 (en) 2002-12-10 2004-06-10 Isis Pharmaceuticals Inc. Modulation of matrix metalloproteinase 11 expression
GB0321615D0 (en) * 2003-09-15 2003-10-15 Glaxo Group Ltd Improvements in vaccination
EA012066B1 (ru) * 2003-10-10 2009-08-28 Паудерджект Вэксинс, Инк. Способ, вызывающий т-клеточный ответ
CA2555013C (en) * 2004-02-11 2013-10-15 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Carcinoembryonic antigen fusions and uses thereof

Also Published As

Publication number Publication date
ES2370040T3 (es) 2011-12-12
EP1934246A2 (en) 2008-06-25
JP5361386B2 (ja) 2013-12-04
CN101365715B (zh) 2013-03-27
AU2006301582B2 (en) 2011-10-13
WO2007042169A3 (en) 2007-05-31
US8106176B2 (en) 2012-01-31
US20120177679A1 (en) 2012-07-12
US8492522B2 (en) 2013-07-23
CA2623531C (en) 2013-12-10
CA2623531A1 (en) 2007-04-19
JP2009509553A (ja) 2009-03-12
CN101365715A (zh) 2009-02-11
EP1934246B8 (en) 2012-02-08
US20090155298A1 (en) 2009-06-18
EP1934246B1 (en) 2011-08-24
WO2007042169A2 (en) 2007-04-19
AU2006301582A1 (en) 2007-04-19

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