ATE52027T1 - Formulierungen mit verzoegerter freisetzung. - Google Patents

Formulierungen mit verzoegerter freisetzung.

Info

Publication number
ATE52027T1
ATE52027T1 AT87108199T AT87108199T ATE52027T1 AT E52027 T1 ATE52027 T1 AT E52027T1 AT 87108199 T AT87108199 T AT 87108199T AT 87108199 T AT87108199 T AT 87108199T AT E52027 T1 ATE52027 T1 AT E52027T1
Authority
AT
Austria
Prior art keywords
release formulations
delayed release
administered
core
produced
Prior art date
Application number
AT87108199T
Other languages
English (en)
Inventor
Reginald Phillips
Krishnayya Bikkina
Sadath U Kahn
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE52027T1 publication Critical patent/ATE52027T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Furan Compounds (AREA)
AT87108199T 1986-06-06 1987-06-05 Formulierungen mit verzoegerter freisetzung. ATE52027T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/871,643 US4816264A (en) 1986-06-06 1986-06-06 Sustained release formulations
EP87108199A EP0248447B1 (de) 1986-06-06 1987-06-05 Formulierungen mit verzögerter Freisetzung

Publications (1)

Publication Number Publication Date
ATE52027T1 true ATE52027T1 (de) 1990-05-15

Family

ID=25357834

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87108199T ATE52027T1 (de) 1986-06-06 1987-06-05 Formulierungen mit verzoegerter freisetzung.

Country Status (17)

Country Link
US (1) US4816264A (de)
EP (1) EP0248447B1 (de)
JP (1) JPS6345216A (de)
KR (1) KR880000088A (de)
AT (1) ATE52027T1 (de)
AU (1) AU603803B2 (de)
CA (1) CA1307205C (de)
DE (1) DE3762309D1 (de)
DK (1) DK288987A (de)
ES (1) ES2014275B3 (de)
FI (1) FI872490A7 (de)
GR (1) GR3000439T3 (de)
NO (1) NO872381L (de)
NZ (1) NZ220410A (de)
PH (1) PH24251A (de)
PT (1) PT85019B (de)
ZA (1) ZA873475B (de)

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US5160743A (en) * 1988-04-28 1992-11-03 Alza Corporation Annealed composition for pharmaceutically acceptable drug
US5006346A (en) * 1988-04-28 1991-04-09 Alza Corporation Delivery system
FR2630913A1 (fr) * 1988-05-09 1989-11-10 Delalande Sa Comprimes de sel(s) hydrosoluble(s) de diltiazem a liberation programmee et leur procede de fabrication
US5612059A (en) * 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
IT1227899B (it) * 1988-12-23 1991-05-14 Poli Ind Chimica Spa Rivestimento totale o parziale di principi attivi farmaceutici e relative composizioni
US5030452A (en) * 1989-01-12 1991-07-09 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Dispensing devices powered by hydrogel
US5108756A (en) * 1989-01-12 1992-04-28 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
US4927639A (en) * 1989-02-02 1990-05-22 Warner-Lambert Company Modified release gemfibrozil composition
US4925676A (en) * 1989-02-02 1990-05-15 Warner-Lambert Company Extended release gemfibrozil composition
US5047258A (en) * 1989-07-14 1991-09-10 Sterling Drug Inc. Aqueous spray-coating process
US5017383A (en) * 1989-08-22 1991-05-21 Taisho Pharmaceutical Co., Ltd. Method of producing fine coated pharmaceutical preparation
US5209933A (en) * 1990-01-10 1993-05-11 Syntex (U.S.A.) Inc. Long acting calcium channel blocker composition
AT397345B (de) * 1990-04-04 1994-03-25 Chemiefaser Lenzing Ag Pharmazeutisches präparat mit verzögerter wirkstofffreisetzung auf basis von hemicellulosen
US5175003A (en) * 1990-04-06 1992-12-29 Biosytes Usa, Inc. Dual mechanism controlled release system for drug dosage forms
EP0462067A1 (de) * 1990-06-15 1991-12-18 Warner-Lambert Company Gemfibrozil-Formulierung
EP0462066A1 (de) * 1990-06-15 1991-12-18 Warner-Lambert Company Amorphes Gemfibrozil
DE69107461T2 (de) * 1990-08-07 1995-06-22 Pfizer Verwendung von interfacial polymerisierten membranen in abgabevorrichtungen.
US5102668A (en) * 1990-10-05 1992-04-07 Kingaform Technology, Inc. Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH
US5656296A (en) * 1992-04-29 1997-08-12 Warner-Lambert Company Dual control sustained release drug delivery systems and methods for preparing same
US5321012A (en) * 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
USRE39300E1 (en) 1993-01-28 2006-09-19 Virginia Commonwealth University Medical College Of Virginia Inhibiting the development of tolerance to and/or dependence on an addictive substance
DE4318375A1 (de) * 1993-05-28 1994-12-01 Rottendorf Pharma Gmbh Mischung zur Schaffung von Filmüberzügen für Tabletten od. dgl.
WO1995006462A1 (en) * 1993-08-30 1995-03-09 Warner-Lambert Company Tablet coating based on a melt-spun mixture of a saccharide and apolymer
US5637319A (en) * 1995-03-01 1997-06-10 Takada; Kanji Controlled-release preparations
US5931809A (en) 1995-07-14 1999-08-03 Depotech Corporation Epidural administration of therapeutic compounds with sustained rate of release
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
KR19980077329A (ko) * 1997-04-18 1998-11-16 이범진 이중층 약물 함유 제어방출성 제제
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
WO2000057838A2 (en) * 1999-03-29 2000-10-05 American Home Products Corporation Coating system
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
GB0002305D0 (en) * 2000-02-01 2000-03-22 Phoqus Limited Power material for electrostatic application
PT1251832E (pt) * 2000-02-04 2007-01-31 Depomed Inc Forma de dosagem constituída por invólucro-e-núcleo que conduz a uma libertação do fármaco de ordem zero
US6855721B1 (en) 2000-07-28 2005-02-15 Indevus Pharmaceuticals, Inc. Methods and compositions for alleviating stuttering
US8133501B2 (en) 2002-02-08 2012-03-13 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled drug delivery
US8685427B2 (en) * 2002-07-31 2014-04-01 Boston Scientific Scimed, Inc. Controlled drug delivery
US8920826B2 (en) * 2002-07-31 2014-12-30 Boston Scientific Scimed, Inc. Medical imaging reference devices
US20040213850A1 (en) * 2003-04-25 2004-10-28 Eleni Dokou Sustained release delivery of a thrombin inhibitor
US20060068015A1 (en) * 2003-10-10 2006-03-30 Per Holm Solid dosage form comprising a fibrate and a statin
EP1680091B1 (de) 2003-10-10 2017-05-31 Veloxis Pharmaceuticals A/S Feste dosierform mit einem fibrat
WO2005105073A1 (en) 2004-04-27 2005-11-10 Medicinova, Inc. Phenoxyalkycarboxylic acid derivatives in the treatment of inflammatory diseases
CA2576232C (en) * 2004-05-14 2009-10-27 Green Cross Corp. Neuroprotective properties of dextrorotatory morphinans
US7497627B2 (en) * 2004-06-07 2009-03-03 Honeywell International Inc. Thrust bearing
JP2007092994A (ja) * 2005-09-02 2007-04-12 Shimadzu Corp 動圧気体軸受
JP5121824B2 (ja) * 2006-06-01 2013-01-16 メルク・シャープ・アンド・ドーム・コーポレーション フェニレフリンの徐放のための薬学的組成物
CN104161736A (zh) * 2006-06-01 2014-11-26 Msd消费保健品公司 包含去氧肾上腺素的缓释药物制剂
US20070286903A1 (en) * 2006-06-13 2007-12-13 Becicka Brian T Composition and method for taste masking
US20080075766A1 (en) * 2006-09-25 2008-03-27 Shun-Por Li Multi-core dosage form having transparent outer coating
CA2766202A1 (en) * 2009-06-29 2011-01-06 Mcneil-Ppc, Inc. Pharmaceutical tablet containing a liquid filled capsule
WO2013018605A1 (ja) 2011-08-01 2013-02-07 Ntn株式会社 スラストフォイル軸受
US8962687B2 (en) 2012-12-05 2015-02-24 Medicinova, Inc. Method of treating liver disorders
JP2013119550A (ja) 2011-12-08 2013-06-17 Medicinova Inc 非アルコール性脂肪性肝疾患及び非アルコール性脂肪性肝炎の処置方法
US20150031769A1 (en) 2013-07-25 2015-01-29 Medicinova, Inc. Methods for reducing triglyceride, total cholesterol and low density lipoprotein blood levels
US20150321989A1 (en) 2014-05-08 2015-11-12 Medicinova, Inc. Method of treating idiopathic pulmonary fibrosis
US9346754B2 (en) 2014-05-08 2016-05-24 Medicinova, Inc. Method of treating advanced non-alcoholic steatohepatitis
CN106470678A (zh) 2014-06-02 2017-03-01 美迪诺亚公司 抑制或治疗纤维化的方法
CA2936741C (en) 2014-10-31 2018-11-06 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
BR112017010700A2 (pt) 2014-11-26 2018-05-08 Medicinova Inc combinação de ibudilaste e riluzol e métodos de uso da mesma
CN118593482A (zh) 2017-12-05 2024-09-06 赛诺维信制药公司 非外消旋混合物及其用途
WO2019113084A1 (en) 2017-12-05 2019-06-13 Sunovion Pharmaceuticals Inc. Crystal forms and production methods thereof
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
MX2021014774A (es) 2019-06-04 2022-02-03 Sunovion Pharmaceuticals Inc Formulaciones de liberacion modificada y usos de las mismas.
WO2022251464A1 (en) 2021-05-28 2022-12-01 Medicinova, Inc. Phenoxyalkylcarboxylic acid derivatives and their use in lowering triglyceride levels

Family Cites Families (13)

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CA1097220A (en) * 1975-10-10 1981-03-10 Aaron L. Weiss Controlled release tablet
US4014334A (en) * 1976-02-02 1977-03-29 Alza Corporation Laminated osmotic system for dispensing beneficial agent
US4008719A (en) * 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
US4252786A (en) * 1979-11-16 1981-02-24 E. R. Squibb & Sons, Inc. Controlled release tablet
US4320759A (en) * 1980-04-28 1982-03-23 Alza Corporation Dispenser with diffuser
US4309996A (en) * 1980-04-28 1982-01-12 Alza Corporation System with microporous releasing diffusor
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
JPS5867616A (ja) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd 腸溶性マイクロカプセル
US4434153A (en) * 1982-03-22 1984-02-28 Alza Corporation Drug delivery system comprising a reservoir containing a plurality of tiny pills
US4389393A (en) * 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4519801A (en) * 1982-07-12 1985-05-28 Alza Corporation Osmotic device with wall comprising cellulose ether and permeability enhancer
US4610870A (en) * 1984-10-05 1986-09-09 E. R. Squibb & Sons, Inc. Controlled release formulation
CH666405A5 (de) * 1985-06-24 1988-07-29 Ciba Geigy Ag Feste, haltbare darreichungsformen mit elastischem filmueberzug.

Also Published As

Publication number Publication date
JPS6345216A (ja) 1988-02-26
PH24251A (en) 1990-05-04
DK288987D0 (da) 1987-06-04
FI872490A0 (fi) 1987-06-03
NZ220410A (en) 1990-05-28
ZA873475B (en) 1987-11-05
KR880000088A (ko) 1988-03-23
PT85019A (en) 1987-07-01
US4816264A (en) 1989-03-28
EP0248447B1 (de) 1990-04-18
DK288987A (da) 1987-12-07
GR3000439T3 (en) 1991-06-28
FI872490L (fi) 1987-12-07
NO872381L (no) 1987-12-07
ES2014275B3 (es) 1990-07-01
EP0248447A2 (de) 1987-12-09
AU7369287A (en) 1987-12-10
PT85019B (pt) 1990-03-08
FI872490A7 (fi) 1987-12-07
CA1307205C (en) 1992-09-08
NO872381D0 (no) 1987-06-05
EP0248447A3 (en) 1988-04-13
DE3762309D1 (de) 1990-05-23
AU603803B2 (en) 1990-11-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee