ATE510833T1 - Verfahren zur herstellung von hochreinem almotriptan - Google Patents

Verfahren zur herstellung von hochreinem almotriptan

Info

Publication number
ATE510833T1
ATE510833T1 AT08773241T AT08773241T ATE510833T1 AT E510833 T1 ATE510833 T1 AT E510833T1 AT 08773241 T AT08773241 T AT 08773241T AT 08773241 T AT08773241 T AT 08773241T AT E510833 T1 ATE510833 T1 AT E510833T1
Authority
AT
Austria
Prior art keywords
almotriptan
pyrrolidinylsulfonylmethyl
formula
salt
high purity
Prior art date
Application number
AT08773241T
Other languages
English (en)
Inventor
Ludek Ridvan
Petr Hruby
Jan Stach
Stanislav Radl
Michal Voslar
Hana Brusova
Lucie Krumbholcova
Monika Zatopkova
Original Assignee
Zentiva Ks
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentiva Ks filed Critical Zentiva Ks
Application granted granted Critical
Publication of ATE510833T1 publication Critical patent/ATE510833T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT08773241T 2007-06-13 2008-06-13 Verfahren zur herstellung von hochreinem almotriptan ATE510833T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ20070408A CZ302424B6 (cs) 2007-06-13 2007-06-13 Zpusob prípravy almotriptanu o vysoké cistote
PCT/CZ2008/000067 WO2008151584A1 (en) 2007-06-13 2008-06-13 Method for the preparation of high purity almotriptan

Publications (1)

Publication Number Publication Date
ATE510833T1 true ATE510833T1 (de) 2011-06-15

Family

ID=39816937

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08773241T ATE510833T1 (de) 2007-06-13 2008-06-13 Verfahren zur herstellung von hochreinem almotriptan

Country Status (6)

Country Link
EP (1) EP2158197B1 (de)
AT (1) ATE510833T1 (de)
CZ (1) CZ302424B6 (de)
EA (1) EA016759B1 (de)
PL (1) PL2158197T3 (de)
WO (1) WO2008151584A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010113183A2 (en) * 2009-04-03 2010-10-07 Msn Laboratories Limited Process for the preparation of 1-[[[3-[2-(dimethylamino)ethyl]-1h-indol-5-yl]methyl]sulfonyl] pyrrolidine and its pharmaceutically acceptable salts
CN102775391B (zh) * 2011-05-12 2015-05-20 上海医药工业研究院 制备抗偏头痛药物阿莫曲坦的方法
CN102775392B (zh) * 2011-05-12 2015-11-18 上海医药工业研究院 N-保护-3，5-二取代吲哚衍生物及其制备方法和应用
CN103724252A (zh) * 2012-10-12 2014-04-16 苏州四同医药科技有限公司 一种阿莫曲坦的制备方法
CN106478484B (zh) * 2016-08-31 2017-11-10 重庆华森制药股份有限公司 一种制备阿莫曲坦关键中间体的方法
HRP20220797T1 (hr) * 2019-11-07 2022-10-14 Small Pharma Ltd Spojevi
US11773062B2 (en) 2021-03-22 2023-10-03 Small Pharma Ltd Deuterated compounds
US11697638B2 (en) 2021-09-08 2023-07-11 Small Pharma Ltd 5-methoxy-N,N-dimethyltryptamine crystalline forms

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9216009D0 (en) * 1992-07-28 1992-09-09 Almirall Lab New indol derivatives
WO2006129190A1 (en) * 2005-06-03 2006-12-07 Glenmark Pharmaceuticals Limited Process for the preparation of almotriptan
EP1907377B1 (de) * 2005-07-25 2013-04-24 Matrix Laboratories Ltd Verfahren zur herstellung von almotriptan
US7619220B2 (en) * 2005-11-30 2009-11-17 Jeol Ltd. Method of measuring aberrations and correcting aberrations using Ronchigram and electron microscope

Also Published As

Publication number Publication date
EA200901626A1 (ru) 2010-06-30
PL2158197T3 (pl) 2011-10-31
EA016759B1 (ru) 2012-07-30
CZ302424B6 (cs) 2011-05-11
CZ2007408A3 (cs) 2008-12-29
EP2158197A1 (de) 2010-03-03
EP2158197B1 (de) 2011-05-25
WO2008151584A1 (en) 2008-12-18

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Legal Events

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