ATE508795T1 - Vorrichtung und verfahren zur erkennung von dna- beschädigung - Google Patents
Vorrichtung und verfahren zur erkennung von dna- beschädigungInfo
- Publication number
- ATE508795T1 ATE508795T1 AT08857721T AT08857721T ATE508795T1 AT E508795 T1 ATE508795 T1 AT E508795T1 AT 08857721 T AT08857721 T AT 08857721T AT 08857721 T AT08857721 T AT 08857721T AT E508795 T1 ATE508795 T1 AT E508795T1
- Authority
- AT
- Austria
- Prior art keywords
- dna damage
- well
- electrode pairs
- detecting dna
- assays
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44773—Multi-stage electrophoresis, e.g. two-dimensional electrophoresis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0829—Multi-well plates; Microtitration plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
- B01L2400/0421—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Clinical Laboratory Science (AREA)
- Hematology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0723725.8A GB0723725D0 (en) | 2007-12-05 | 2007-12-05 | Apparatus and method for detecting dna damage |
PCT/EP2008/066895 WO2009071665A1 (en) | 2007-12-05 | 2008-12-05 | Apparatus and method for detecting dna damage |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE508795T1 true ATE508795T1 (de) | 2011-05-15 |
Family
ID=38982976
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08857721T ATE508795T1 (de) | 2007-12-05 | 2008-12-05 | Vorrichtung und verfahren zur erkennung von dna- beschädigung |
Country Status (9)
Country | Link |
---|---|
US (2) | US20120058467A1 (de) |
EP (1) | EP2234724B1 (de) |
JP (1) | JP5599718B2 (de) |
CN (1) | CN101939106B (de) |
AT (1) | ATE508795T1 (de) |
AU (1) | AU2008333180A1 (de) |
CA (1) | CA2707662A1 (de) |
GB (1) | GB0723725D0 (de) |
WO (1) | WO2009071665A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101788527B (zh) * | 2010-03-09 | 2013-01-23 | 浙江大学 | 用于单细胞凝胶电泳试验的成套装置 |
US9128046B2 (en) * | 2011-10-31 | 2015-09-08 | Cellomics, Inc. | Slide holder assembly for comet assay |
EP2918667B1 (de) * | 2012-12-12 | 2017-11-01 | National University Corporation Toyohashi University of Technology | Fremdstoffeinführungsvorrichtung und verfahren zur herstellung von zellen mit integrierten fremdstoffen |
KR20140123243A (ko) * | 2013-04-12 | 2014-10-22 | 주식회사 나노엔텍 | 단일세포 전기영동측정칩, 칩 홀딩유닛 및 단일세포 전기영동처리장치 |
DE102013212811A1 (de) | 2013-07-01 | 2015-01-08 | Leica Microsystems Cms Gmbh | Lasermikrodissektionssystem und Untersuchungsverfahren für nukleinsäurehaltige Proben |
CN106029904A (zh) | 2013-11-17 | 2016-10-12 | 宽腾矽公司 | 用于探测、检测和分析分子的具有外部光源的集成装置 |
CN103952302B (zh) * | 2014-04-15 | 2016-02-17 | 同济大学 | 一种用于单细胞胶电泳实验的新型基片 |
US11513076B2 (en) | 2016-06-15 | 2022-11-29 | Ludwig-Maximilians-Universität München | Single molecule detection or quantification using DNA nanotechnology |
CN107576713B (zh) * | 2017-07-12 | 2019-09-27 | 浙江省农业科学院 | 一种检测蚯蚓体腔细胞dna损伤的方法及其运用 |
BR112020000826A2 (pt) * | 2017-07-24 | 2020-07-21 | Quantum-Si Incorporated | instrumento bio-optoeletrônico maciçamente paralelo portátil |
EP3508841A1 (de) * | 2018-01-08 | 2019-07-10 | 4D Lifetec AG | Einzelzellengelelektrophorese |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4473452A (en) * | 1982-11-18 | 1984-09-25 | The Trustees Of Columbia University In The City Of New York | Electrophoresis using alternating transverse electric fields |
US5137817A (en) * | 1990-10-05 | 1992-08-11 | Amoco Corporation | Apparatus and method for electroporation |
EP0950184A1 (de) * | 1996-06-27 | 1999-10-20 | Cellstat Technologies, Inc. | Verfahren und vorrichtung zum sieben mit hohem durchsatz |
EP0947249A1 (de) * | 1998-03-18 | 1999-10-06 | Corning Incorporated | Extrudierte Matrixplatte mit hoher Dichte |
US6969449B2 (en) * | 2000-07-10 | 2005-11-29 | Vertex Pharmaceuticals (San Diego) Llc | Multi-well plate and electrode assemblies for ion channel assays |
DE60143064D1 (de) * | 2000-07-10 | 2010-10-21 | Vertex Pharma San Diego Llc | Ionenkanal-Assayverfahren |
KR20020012915A (ko) * | 2000-08-09 | 2002-02-20 | 유상옥,송운한 | 자외선에 대한 피부보호용 도화추출물-함유 조성물 |
US20050009004A1 (en) * | 2002-05-04 | 2005-01-13 | Jia Xu | Apparatus including ion transport detecting structures and methods of use |
WO2003052375A2 (en) * | 2001-08-06 | 2003-06-26 | Vanderbilt University | Device and methods for monitoring the status of at least one cell |
JP2003210155A (ja) * | 2002-01-21 | 2003-07-29 | Hitachi Plant Eng & Constr Co Ltd | コメットアッセイ解析装置 |
JP3896458B2 (ja) * | 2002-09-17 | 2007-03-22 | 独立行政法人放射線医学総合研究所 | 試料の搭載方法 |
JP2004108972A (ja) * | 2002-09-19 | 2004-04-08 | Hitachi Plant Eng & Constr Co Ltd | 液体の有害性診断方法 |
US20050000811A1 (en) * | 2003-05-06 | 2005-01-06 | Janos Luka | Electrophoretically enhanced methods |
US7169609B2 (en) * | 2004-03-31 | 2007-01-30 | Vertex Pharmaceutcals, Inc. | Multiwell plate assembly for use in high throughput assays |
DE102004042729B4 (de) * | 2004-09-03 | 2018-02-01 | Robert Bosch Gmbh | Bio-Chip mit einem Elektrodenarray auf einem Substrat |
DE102004046364A1 (de) * | 2004-09-24 | 2006-03-30 | Intox Gmbh | Verfahren zur Bestimmung von DNA- Schäden und Vielkammer-Behälter |
JP4355832B2 (ja) * | 2005-07-14 | 2009-11-04 | パナソニックエコシステムズ株式会社 | コメットアッセイ解析方法およびコメットアッセイ画像解析装置およびコメットアッセイ解析装置 |
WO2007103116A2 (en) * | 2006-03-02 | 2007-09-13 | Laboratory Corporation Of America Holdings | Methods and systems for evaluating health risk factors by measurement of dna damage and dna repair |
-
2007
- 2007-12-05 GB GBGB0723725.8A patent/GB0723725D0/en not_active Ceased
-
2008
- 2008-12-05 US US12/746,169 patent/US20120058467A1/en not_active Abandoned
- 2008-12-05 WO PCT/EP2008/066895 patent/WO2009071665A1/en active Application Filing
- 2008-12-05 AT AT08857721T patent/ATE508795T1/de not_active IP Right Cessation
- 2008-12-05 CA CA2707662A patent/CA2707662A1/en not_active Abandoned
- 2008-12-05 EP EP08857721A patent/EP2234724B1/de not_active Not-in-force
- 2008-12-05 JP JP2010536472A patent/JP5599718B2/ja not_active Expired - Fee Related
- 2008-12-05 AU AU2008333180A patent/AU2008333180A1/en not_active Abandoned
- 2008-12-05 CN CN200880126456.5A patent/CN101939106B/zh not_active Expired - Fee Related
-
2013
- 2013-02-28 US US13/780,035 patent/US20130177903A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20120058467A1 (en) | 2012-03-08 |
EP2234724B1 (de) | 2011-05-11 |
CN101939106B (zh) | 2014-09-24 |
US20130177903A1 (en) | 2013-07-11 |
CA2707662A1 (en) | 2009-06-11 |
JP2011507492A (ja) | 2011-03-10 |
CN101939106A (zh) | 2011-01-05 |
AU2008333180A1 (en) | 2009-06-11 |
EP2234724A1 (de) | 2010-10-06 |
WO2009071665A1 (en) | 2009-06-11 |
GB0723725D0 (en) | 2008-01-16 |
AU2008333180A8 (en) | 2010-08-19 |
JP5599718B2 (ja) | 2014-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |