ATE50594T1 - Verfahren zur reinigung des tollwutvirus. - Google Patents

Verfahren zur reinigung des tollwutvirus.

Info

Publication number
ATE50594T1
ATE50594T1 AT85110047T AT85110047T ATE50594T1 AT E50594 T1 ATE50594 T1 AT E50594T1 AT 85110047 T AT85110047 T AT 85110047T AT 85110047 T AT85110047 T AT 85110047T AT E50594 T1 ATE50594 T1 AT E50594T1
Authority
AT
Austria
Prior art keywords
rabies virus
cleaning
procedure
rabies
chromatography
Prior art date
Application number
AT85110047T
Other languages
German (de)
English (en)
Inventor
Kuniaki Sakamoto
Kunio Ohkuma
Tetsuo Kawahara
Mitsuo Sakoh
Original Assignee
Chemo Sero Therapeut Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeut Res Inst filed Critical Chemo Sero Therapeut Res Inst
Application granted granted Critical
Publication of ATE50594T1 publication Critical patent/ATE50594T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/205—Rhabdoviridae, e.g. rabies virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20111—Lyssavirus, e.g. rabies virus
    • C12N2760/20151—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Filtering Of Dispersed Particles In Gases (AREA)
  • Activated Sludge Processes (AREA)
  • Detergent Compositions (AREA)
AT85110047T 1984-08-10 1985-08-09 Verfahren zur reinigung des tollwutvirus. ATE50594T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59168226A JPS6147187A (ja) 1984-08-10 1984-08-10 狂犬病ウイルスの精製方法
EP85110047A EP0171771B1 (en) 1984-08-10 1985-08-09 A method for purification of rabies virus

Publications (1)

Publication Number Publication Date
ATE50594T1 true ATE50594T1 (de) 1990-03-15

Family

ID=15864114

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85110047T ATE50594T1 (de) 1984-08-10 1985-08-09 Verfahren zur reinigung des tollwutvirus.

Country Status (7)

Country Link
US (1) US4725547A (esLanguage)
EP (1) EP0171771B1 (esLanguage)
JP (1) JPS6147187A (esLanguage)
KR (1) KR920009734B1 (esLanguage)
AT (1) ATE50594T1 (esLanguage)
CA (1) CA1251398A (esLanguage)
DE (1) DE3576172D1 (esLanguage)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5447859A (en) * 1993-07-16 1995-09-05 Viagene Method for the purification or removal of retroviruses using sulfated cellulose
US7732129B1 (en) * 1998-12-01 2010-06-08 Crucell Holland B.V. Method for the production and purification of adenoviral vectors
ATE348155T1 (de) * 1996-11-20 2007-01-15 Introgen Therapeutics Inc Ein verbessertes verfahren zur produktion und reinigung von adenoviralen vektoren
US6689600B1 (en) 1998-11-16 2004-02-10 Introgen Therapeutics, Inc. Formulation of adenovirus for gene therapy
JP2002142770A (ja) 2000-11-08 2002-05-21 Dnavec Research Inc 循環系への遺伝子送達用パラミクソウイルスベクター
PL354822A1 (en) * 2002-06-30 2004-01-12 Instytut Immunologii i Terapii Doświadczalnej PANwe Wrocławiu Method of receiving purified bacteriophage preparations and new applications of polysaccharide or its esterificated derivative
WO2004112707A2 (en) * 2003-06-18 2004-12-29 Onyx Pharmaceuticals, Inc. Method for purifying virus
CN1902312B (zh) 2003-11-04 2011-02-23 株式会社载体研究所 制备导入了基因的树突细胞的方法
JP2008518632A (ja) * 2004-11-03 2008-06-05 イントロゲン セラピューティックス， インコーポレイテッド アデノウイルスベクターの製造および精製のための新規方法
EP1916298B1 (en) 2005-06-14 2011-12-28 Dnavec Corporation Methods for producing monoclonal antibodies
US20100167341A1 (en) 2006-01-17 2010-07-01 Dnavec Corporation Novel protein expression system
CA2658266A1 (en) 2006-07-13 2008-01-17 Dnavec Corporation Non-replicating paramyxoviridae virus vector
WO2008136438A1 (ja) 2007-04-27 2008-11-13 Kyushu University, National University Corporation 遺伝子治療用ウイルスベクター
FR2944292B1 (fr) * 2009-04-08 2013-08-23 Sanofi Pasteur Procede de purification du virus rabique
WO2011130119A2 (en) 2010-04-14 2011-10-20 Millipore Corporation Methods of producing high titer, high purity virus stocks and methods of use thereof
DE102013017014B4 (de) 2013-10-14 2017-03-30 Sartorius Stedim Biotech Gmbh Sulfatierte Cellulosehydrat-Membran, Verfahren zur ihrer Herstellung und Verwendung der Membran als Adsorptionsmembran für die Virenaufreinigung
ES2975182T3 (es) 2017-03-06 2024-07-03 Guangzhou Realbenefitspot Pharmaceutical Co Ltd Métodos de producción y caracterización de vacunas víricas y composición de vacuna vírica
EP3420076B1 (en) * 2017-03-06 2024-02-21 Guangzhou Realbenefitspot Pharmaceutical Co., Ltd. Methods of producing and characterizing virus vaccine and virus vaccine composition
CN108993456B (zh) * 2018-07-26 2021-02-26 武汉汇研生物科技股份有限公司 一种狂犬病毒吸附层析介质及其制备方法
CN113607838A (zh) * 2021-07-29 2021-11-05 长春卓谊生物股份有限公司 一种β-丙內酯残留量检测方法及其应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL131092C (esLanguage) *
US3105012A (en) * 1961-10-19 1963-09-24 Parke Davis & Co Antigen products and means for producing the same
SE356735B (esLanguage) * 1970-12-02 1973-06-04 Svenska Cellulosa Ab
US3973000A (en) * 1972-02-04 1976-08-03 Eli Lilly And Company Process for purified rabies vaccine
US3842062A (en) * 1972-09-27 1974-10-15 Du Pont Water-soluble complexes of protein and anionic polyelectrolytes such as sodium carboxymethyl cellulose
US3920625A (en) * 1973-06-19 1975-11-18 Kabi Ab Isolation of coagulation factors from biological material using cross linked sulfated, sulfonated carbohydrates
US4160018A (en) * 1973-06-25 1979-07-03 Bjorklund Knut B Stabilized cancer associated polypeptide antigen and preparation thereof
IL49752A (en) * 1975-07-09 1979-07-25 Kabi Ab Compositions having affinity for hepatitis virus and method for hepatitis virus removal or concentration
SE420977B (sv) * 1976-03-18 1981-11-16 Kabi Ab Forfarande for rening och isolering av hepatitvirus for vaccinframstellning
DE2616407C3 (de) * 1976-04-14 1980-02-21 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Tollwut-Impfstoffs
GB1596653A (en) * 1977-01-26 1981-08-26 Gist Brocades Nv Vaccine
US4181713A (en) * 1978-10-30 1980-01-01 Merck & Co., Inc. Isolation of HBs Ag
CH638985A5 (de) * 1979-04-10 1983-10-31 Schweiz Serum & Impfinst Verfahren zur herstellung eines tollwutimpfstoffes und danach erhaltener impfstoff.
JPS57136528A (en) * 1981-02-09 1982-08-23 Hayashibara Biochem Lab Inc Preparation of viral vaccine
US4434093A (en) * 1982-07-26 1984-02-28 Ortho Diagnostic Systems Inc. Methods for preparation of HBs Ag free gamma globulins
US4515714A (en) * 1983-03-09 1985-05-07 Juridicial Foundation, The Chemo-Semo-Sero-Therapeutic Research Institute Method for purification of hepatitis B virus surface antigen

Also Published As

Publication number Publication date
CA1251398A (en) 1989-03-21
DE3576172D1 (de) 1990-04-05
JPS6230753B2 (esLanguage) 1987-07-03
EP0171771A3 (en) 1988-01-07
EP0171771A2 (en) 1986-02-19
JPS6147187A (ja) 1986-03-07
EP0171771B1 (en) 1990-02-28
KR920009734B1 (ko) 1992-10-22
US4725547A (en) 1988-02-16
KR870001836A (ko) 1987-03-28

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties