ATE503003T1 - Verfahren zur herstellung rekombinanter polypeptide - Google Patents
Verfahren zur herstellung rekombinanter polypeptideInfo
- Publication number
- ATE503003T1 ATE503003T1 AT04764305T AT04764305T ATE503003T1 AT E503003 T1 ATE503003 T1 AT E503003T1 AT 04764305 T AT04764305 T AT 04764305T AT 04764305 T AT04764305 T AT 04764305T AT E503003 T1 ATE503003 T1 AT E503003T1
- Authority
- AT
- Austria
- Prior art keywords
- recombinant polypeptides
- producing recombinant
- relates
- periplasm
- polypeptide
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 210000001322 periplasm Anatomy 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000011143 downstream manufacturing Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0319601.1A GB0319601D0 (en) | 2003-08-20 | 2003-08-20 | Production process |
| PCT/EP2004/009321 WO2005019466A2 (en) | 2003-08-20 | 2004-08-19 | Process for the preparation of recombinant polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE503003T1 true ATE503003T1 (de) | 2011-04-15 |
Family
ID=28460018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04764305T ATE503003T1 (de) | 2003-08-20 | 2004-08-19 | Verfahren zur herstellung rekombinanter polypeptide |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8426168B2 (de) |
| EP (2) | EP2302068B2 (de) |
| JP (1) | JP4750030B2 (de) |
| AT (1) | ATE503003T1 (de) |
| DE (1) | DE602004031955D1 (de) |
| GB (1) | GB0319601D0 (de) |
| PL (2) | PL2302068T3 (de) |
| SI (2) | SI1658376T1 (de) |
| WO (1) | WO2005019466A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0425534D0 (en) | 2004-11-19 | 2004-12-22 | Celltech R&D Ltd | Process for obtaining antibodies |
| EP1882743A4 (de) * | 2005-05-12 | 2012-08-01 | Ajinomoto Kk | Proteinherstellungsverfahren |
| GB201001791D0 (en) * | 2010-02-03 | 2010-03-24 | Ucb Pharma Sa | Process for obtaining antibodies |
| GB201106225D0 (en) * | 2011-04-13 | 2011-05-25 | Glaxosmithkline Biolog Sa | Fermentation process |
| SG11201404991YA (en) | 2012-02-23 | 2014-09-26 | Stage Cell Therapeutics Gmbh | Chromatographic isolation of cells and other complex biological materials |
| CN105263527A (zh) | 2012-12-27 | 2016-01-20 | 格林考瓦因有限公司 | 与crm197有关的方法和组合物 |
| US10358460B2 (en) | 2014-12-22 | 2019-07-23 | Ucb Biopharma Sprl | Protein manufacture |
| MX395154B (es) | 2015-10-22 | 2025-03-25 | Juno Therapeutics Gmbh | Métodos, kits, agentes y aparatos para transducción. |
| MA45489A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés de culture de cellules, kits et appareil associés |
| SG11201909931PA (en) | 2017-04-27 | 2019-11-28 | Juno Therapeutics Gmbh | Oligomeric particle reagents and methods of use thereof |
| EP3874024A1 (de) | 2018-10-31 | 2021-09-08 | Juno Therapeutics GmbH | Verfahren zur selektion und stimulation von zellen und vorrichtung dafür |
| CN111996225A (zh) * | 2020-09-18 | 2020-11-27 | 深圳科兴药业有限公司 | 一种利用微生物生产高活性重组人干扰素α2b的发酵方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4315852A (en) | 1980-11-26 | 1982-02-16 | Schering Corporation | Extraction of interferon from bacteria |
| ATE78515T1 (de) * | 1984-10-05 | 1992-08-15 | Genentech Inc | Dna, zellkulturen und verfahren zur sekretion von heterologen proteinen und periplasmische proteinrueckgewinnung. |
| US4680262A (en) * | 1984-10-05 | 1987-07-14 | Genentech, Inc. | Periplasmic protein recovery |
| DE3511011A1 (de) | 1985-03-27 | 1986-10-02 | Hoechst Ag, 6230 Frankfurt | Verfahren zur isolierung und reinigung von (alpha)-interferonen |
| JP3951062B2 (ja) * | 1991-09-19 | 2007-08-01 | ジェネンテック・インコーポレーテッド | 少なくとも遊離のチオールとして存在するシステインを有する抗体フラグメントの大腸菌での発現、２官能性Ｆ（ａｂ’）２抗体の産生のための使用 |
| DE69318909T2 (de) * | 1992-09-09 | 1998-12-24 | Mitsui Chemicals, Inc., Tokio/Tokyo | Verfahren zur Herstellung von menschlichem Wachstumshormon |
| EP0626448A3 (de) * | 1993-05-26 | 1998-01-14 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Verfahren zur Herstellung und Reinigung von alpha-Interferon |
| US6337205B1 (en) * | 1998-01-06 | 2002-01-08 | Integrated Biosystems, Inc | Cryopreservation vial apparatus and methods |
| GB9808720D0 (en) * | 1998-04-23 | 1998-06-24 | Smithkline Beecham Biolog | Novel compounds |
| AU731758B2 (en) * | 1998-07-08 | 2001-04-05 | Mitsui Chemicals, Inc. | Method for secretory production of human growth hormone |
| CA2369622C (en) * | 1999-04-09 | 2011-06-14 | Universitat Zurich | Novel method for the stabilization of chimeric immunoglobulins or immunoglobulin fragments, and stabilized anti-egp-2 scfv fragment |
| KR100360594B1 (ko) * | 2000-01-19 | 2002-11-13 | 한미약품공업 주식회사 | 인간 인터페론 알파의 발현 분비벡터 및 이를 이용한인터페론 알파의 생산 방법 |
| GB0013810D0 (en) * | 2000-06-06 | 2000-07-26 | Celltech Chiroscience Ltd | Biological products |
| WO2003004599A2 (en) * | 2001-07-02 | 2003-01-16 | Insight Biopharmaceuticals Ltd. | Methods of making and using expression constructs for the expression of recombinant proteins |
| US7829323B2 (en) † | 2004-11-30 | 2010-11-09 | Merial Limited | Mixing devices for chemical lysis of cells |
| EP2459725B1 (de) † | 2009-07-27 | 2019-01-16 | The University Of Wyoming Research Corporation | Biologisch reine brennstoffverarbeitungssysteme und -verfahren |
| US20130039898A1 (en) † | 2010-02-04 | 2013-02-14 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase variants and methods of using compositions thereof |
-
2003
- 2003-08-20 GB GBGB0319601.1A patent/GB0319601D0/en not_active Ceased
-
2004
- 2004-08-19 JP JP2006523607A patent/JP4750030B2/ja not_active Expired - Fee Related
- 2004-08-19 US US10/568,329 patent/US8426168B2/en not_active Expired - Fee Related
- 2004-08-19 EP EP10009128.9A patent/EP2302068B2/de not_active Expired - Lifetime
- 2004-08-19 AT AT04764305T patent/ATE503003T1/de active
- 2004-08-19 DE DE602004031955T patent/DE602004031955D1/de not_active Expired - Lifetime
- 2004-08-19 WO PCT/EP2004/009321 patent/WO2005019466A2/en not_active Ceased
- 2004-08-19 EP EP04764305A patent/EP1658376B1/de not_active Revoked
- 2004-08-19 PL PL10009128.9T patent/PL2302068T3/pl unknown
- 2004-08-19 SI SI200431654T patent/SI1658376T1/sl unknown
- 2004-08-19 SI SI200432326A patent/SI2302068T1/sl unknown
- 2004-08-19 PL PL04764305T patent/PL1658376T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005019466A2 (en) | 2005-03-03 |
| EP1658376B1 (de) | 2011-03-23 |
| US8426168B2 (en) | 2013-04-23 |
| SI1658376T1 (sl) | 2011-06-30 |
| EP2302068B1 (de) | 2016-03-30 |
| GB0319601D0 (en) | 2003-09-24 |
| PL2302068T3 (pl) | 2016-09-30 |
| DE602004031955D1 (de) | 2011-05-05 |
| PL1658376T3 (pl) | 2011-08-31 |
| SI2302068T1 (sl) | 2016-07-29 |
| WO2005019466A3 (en) | 2005-05-06 |
| JP4750030B2 (ja) | 2011-08-17 |
| EP2302068A1 (de) | 2011-03-30 |
| EP1658376A2 (de) | 2006-05-24 |
| EP2302068B2 (de) | 2022-10-26 |
| US20060269990A1 (en) | 2006-11-30 |
| JP2007502609A (ja) | 2007-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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