ATE503003T1 - Verfahren zur herstellung rekombinanter polypeptide - Google Patents
Verfahren zur herstellung rekombinanter polypeptideInfo
- Publication number
- ATE503003T1 ATE503003T1 AT04764305T AT04764305T ATE503003T1 AT E503003 T1 ATE503003 T1 AT E503003T1 AT 04764305 T AT04764305 T AT 04764305T AT 04764305 T AT04764305 T AT 04764305T AT E503003 T1 ATE503003 T1 AT E503003T1
- Authority
- AT
- Austria
- Prior art keywords
- recombinant polypeptides
- producing recombinant
- relates
- periplasm
- polypeptide
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 210000001322 periplasm Anatomy 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000011143 downstream manufacturing Methods 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0319601.1A GB0319601D0 (en) | 2003-08-20 | 2003-08-20 | Production process |
| PCT/EP2004/009321 WO2005019466A2 (en) | 2003-08-20 | 2004-08-19 | Process for the preparation of recombinant polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE503003T1 true ATE503003T1 (de) | 2011-04-15 |
Family
ID=28460018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04764305T ATE503003T1 (de) | 2003-08-20 | 2004-08-19 | Verfahren zur herstellung rekombinanter polypeptide |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8426168B2 (de) |
| EP (2) | EP2302068B2 (de) |
| JP (1) | JP4750030B2 (de) |
| AT (1) | ATE503003T1 (de) |
| DE (1) | DE602004031955D1 (de) |
| GB (1) | GB0319601D0 (de) |
| PL (2) | PL1658376T3 (de) |
| SI (2) | SI1658376T1 (de) |
| WO (1) | WO2005019466A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0425534D0 (en) * | 2004-11-19 | 2004-12-22 | Celltech R&D Ltd | Process for obtaining antibodies |
| BRPI0609675A2 (pt) * | 2005-05-12 | 2011-10-18 | Ajinomoto Kk | método para produzir uma proteìna |
| GB201001791D0 (en) | 2010-02-03 | 2010-03-24 | Ucb Pharma Sa | Process for obtaining antibodies |
| GB201106225D0 (en) * | 2011-04-13 | 2011-05-25 | Glaxosmithkline Biolog Sa | Fermentation process |
| RU2746407C1 (ru) | 2012-02-23 | 2021-04-13 | Стейдж Селл Терапеутикс Гмбх | Хроматографическое выделение клеток и других сложных биологических материалов |
| WO2014102265A1 (en) | 2012-12-27 | 2014-07-03 | Glycovaxyn Ag | Methods and compositions relating to crm197 |
| BR112017013394B1 (pt) | 2014-12-22 | 2024-02-06 | Ucb Biopharma Sprl | Método para fabricar proteína de interesse |
| JP7194020B2 (ja) | 2015-10-22 | 2022-12-21 | ジュノ セラピューティクス ゲーエムベーハー | 細胞の培養方法ならびにそのためのキットおよび装置 |
| US11248238B2 (en) | 2015-10-22 | 2022-02-15 | Juno Therapeutics Gmbh | Methods, kits, agents and apparatuses for transduction |
| JP7339160B2 (ja) | 2017-04-27 | 2023-09-05 | ジュノ セラピューティクス ゲーエムベーハー | オリゴマー粒子試薬およびその使用方法 |
| EP3874024A1 (de) | 2018-10-31 | 2021-09-08 | Juno Therapeutics GmbH | Verfahren zur selektion und stimulation von zellen und vorrichtung dafür |
| CN111996225A (zh) * | 2020-09-18 | 2020-11-27 | 深圳科兴药业有限公司 | 一种利用微生物生产高活性重组人干扰素α2b的发酵方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4315852A (en) | 1980-11-26 | 1982-02-16 | Schering Corporation | Extraction of interferon from bacteria |
| ATE78515T1 (de) * | 1984-10-05 | 1992-08-15 | Genentech Inc | Dna, zellkulturen und verfahren zur sekretion von heterologen proteinen und periplasmische proteinrueckgewinnung. |
| US4680262A (en) | 1984-10-05 | 1987-07-14 | Genentech, Inc. | Periplasmic protein recovery |
| DE3511011A1 (de) | 1985-03-27 | 1986-10-02 | Hoechst Ag, 6230 Frankfurt | Verfahren zur isolierung und reinigung von (alpha)-interferonen |
| WO1993006217A1 (en) | 1991-09-19 | 1993-04-01 | Genentech, Inc. | EXPRESSION IN E. COLI OF ANTIBODY FRAGMENTS HAVING AT LEAST A CYSTEINE PRESENT AS A FREE THIOL, USE FOR THE PRODUCTION OF BIFUNCTIONAL F(ab')2 ANTIBODIES |
| US5496713A (en) * | 1992-09-09 | 1996-03-05 | Mitsui Toatsu Chemicals, Inc. | Process for producing 20 kD human growth hormone |
| EP0626448A3 (de) * | 1993-05-26 | 1998-01-14 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Verfahren zur Herstellung und Reinigung von alpha-Interferon |
| US6337205B1 (en) * | 1998-01-06 | 2002-01-08 | Integrated Biosystems, Inc | Cryopreservation vial apparatus and methods |
| GB9808720D0 (en) * | 1998-04-23 | 1998-06-24 | Smithkline Beecham Biolog | Novel compounds |
| US6160089A (en) * | 1998-07-08 | 2000-12-12 | Mitsui Chemicals, Inc. | Method for secretory production of human growth hormone |
| ATE399796T1 (de) * | 1999-04-09 | 2008-07-15 | Univ Zuerich | Verfahren zur stabilisierung von chimären immunoglobulinen oder immunoglobulinfragmenten und stabilisiertes anti-egp-2-scfv-fragment |
| KR100360594B1 (ko) * | 2000-01-19 | 2002-11-13 | 한미약품공업 주식회사 | 인간 인터페론 알파의 발현 분비벡터 및 이를 이용한인터페론 알파의 생산 방법 |
| GB0013810D0 (en) | 2000-06-06 | 2000-07-26 | Celltech Chiroscience Ltd | Biological products |
| WO2003004599A2 (en) * | 2001-07-02 | 2003-01-16 | Insight Biopharmaceuticals Ltd. | Methods of making and using expression constructs for the expression of recombinant proteins |
| US7829323B2 (en) † | 2004-11-30 | 2010-11-09 | Merial Limited | Mixing devices for chemical lysis of cells |
| EP2459725B1 (de) † | 2009-07-27 | 2019-01-16 | The University Of Wyoming Research Corporation | Biologisch reine brennstoffverarbeitungssysteme und -verfahren |
| ES2582459T3 (es) † | 2010-02-04 | 2016-09-13 | Biomarin Pharmaceutical Inc. | Composiciones de variantes de fenilalanina amoníaco-liasa de procariotas y métodos de uso de sus composiciones |
-
2003
- 2003-08-20 GB GBGB0319601.1A patent/GB0319601D0/en not_active Ceased
-
2004
- 2004-08-19 SI SI200431654T patent/SI1658376T1/sl unknown
- 2004-08-19 EP EP10009128.9A patent/EP2302068B2/de not_active Expired - Lifetime
- 2004-08-19 DE DE602004031955T patent/DE602004031955D1/de not_active Expired - Lifetime
- 2004-08-19 US US10/568,329 patent/US8426168B2/en not_active Expired - Fee Related
- 2004-08-19 AT AT04764305T patent/ATE503003T1/de active
- 2004-08-19 SI SI200432326A patent/SI2302068T1/sl unknown
- 2004-08-19 JP JP2006523607A patent/JP4750030B2/ja not_active Expired - Fee Related
- 2004-08-19 WO PCT/EP2004/009321 patent/WO2005019466A2/en not_active Ceased
- 2004-08-19 PL PL04764305T patent/PL1658376T3/pl unknown
- 2004-08-19 PL PL10009128.9T patent/PL2302068T3/pl unknown
- 2004-08-19 EP EP04764305A patent/EP1658376B1/de not_active Revoked
Also Published As
| Publication number | Publication date |
|---|---|
| JP4750030B2 (ja) | 2011-08-17 |
| EP2302068A1 (de) | 2011-03-30 |
| WO2005019466A2 (en) | 2005-03-03 |
| SI2302068T1 (sl) | 2016-07-29 |
| WO2005019466A3 (en) | 2005-05-06 |
| DE602004031955D1 (de) | 2011-05-05 |
| EP1658376A2 (de) | 2006-05-24 |
| PL2302068T3 (pl) | 2016-09-30 |
| SI1658376T1 (sl) | 2011-06-30 |
| US8426168B2 (en) | 2013-04-23 |
| EP1658376B1 (de) | 2011-03-23 |
| EP2302068B1 (de) | 2016-03-30 |
| JP2007502609A (ja) | 2007-02-15 |
| PL1658376T3 (pl) | 2011-08-31 |
| GB0319601D0 (en) | 2003-09-24 |
| EP2302068B2 (de) | 2022-10-26 |
| US20060269990A1 (en) | 2006-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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