ATE495192T1 - Mit voluminösen oder lipophilen gruppen modifizierte cyctotoxische peptide - Google Patents
Mit voluminösen oder lipophilen gruppen modifizierte cyctotoxische peptideInfo
- Publication number
- ATE495192T1 ATE495192T1 AT99941773T AT99941773T ATE495192T1 AT E495192 T1 ATE495192 T1 AT E495192T1 AT 99941773 T AT99941773 T AT 99941773T AT 99941773 T AT99941773 T AT 99941773T AT E495192 T1 ATE495192 T1 AT E495192T1
- Authority
- AT
- Austria
- Prior art keywords
- cyctotoxic
- voluminous
- lipophilic groups
- peptides modified
- well
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9818938.4A GB9818938D0 (en) | 1998-08-28 | 1998-08-28 | Bioactive peptides |
PCT/GB1999/002850 WO2000012541A2 (en) | 1998-08-28 | 1999-08-31 | Cytotoxic peptides modified by bulky or lipophilic moieties |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE495192T1 true ATE495192T1 (de) | 2011-01-15 |
Family
ID=10838089
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99941773T ATE495192T1 (de) | 1998-08-28 | 1999-08-31 | Mit voluminösen oder lipophilen gruppen modifizierte cyctotoxische peptide |
AT99941774T ATE513847T1 (de) | 1998-08-28 | 1999-08-31 | Bioaktive peptide |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99941774T ATE513847T1 (de) | 1998-08-28 | 1999-08-31 | Bioaktive peptide |
Country Status (12)
Country | Link |
---|---|
US (3) | US6890902B2 (de) |
EP (2) | EP1109827B1 (de) |
JP (1) | JP5475937B2 (de) |
AT (2) | ATE495192T1 (de) |
AU (2) | AU5526899A (de) |
CA (2) | CA2341037C (de) |
DE (1) | DE69943130D1 (de) |
DK (1) | DK1109831T3 (de) |
ES (1) | ES2359616T3 (de) |
GB (1) | GB9818938D0 (de) |
NO (1) | NO333073B1 (de) |
WO (2) | WO2000012541A2 (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9818938D0 (en) | 1998-08-28 | 1998-10-21 | Alpharma As | Bioactive peptides |
GB0605685D0 (en) * | 2006-03-21 | 2006-05-03 | Lytix Biopharma As | Inhibition of tumour growth |
US8283315B2 (en) | 1998-08-28 | 2012-10-09 | Lytix Biopharma As | Inhibition of tumour growth |
US6399570B1 (en) * | 1999-02-05 | 2002-06-04 | Agennix, Inc. | Antimicrobial/endotoxin neutralizing polypeptide |
GB0005702D0 (en) * | 2000-03-09 | 2000-05-03 | Alpharma As | Method |
GB0005703D0 (en) | 2000-03-09 | 2000-05-03 | Alpharma As | Compounds |
KR20020080731A (ko) * | 2001-04-17 | 2002-10-26 | 주식회사 이지바이오 시스템 | 락토페리신 유전자 및 이를 도입한 락토페리신 발현용형질전환체 |
KR100454595B1 (ko) * | 2001-11-30 | 2004-10-28 | 주식회사 이지바이오 시스템 | 락토페리신 유전자 및 이를 도입한 형질전환 대장균 |
SE0200598D0 (sv) * | 2002-02-27 | 2002-02-27 | A & Science Invest Ab | Pharmaceutical composition and method for treatment or prevention of vascular disease or states of tissue hypoperfusion with hypoxic and/or ischemic consequences |
US20040082504A1 (en) | 2002-05-10 | 2004-04-29 | Atul Varadhachary | Intratumorally administered lactoferrin in the treatment of malignant neoplasms and other hyperproliferative diseases |
AU2003247826B2 (en) * | 2002-06-28 | 2008-04-24 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Tryptophan as a functional replacement for ADP-ribose-arginine in recombinant proteins |
NO20031818D0 (no) * | 2003-04-23 | 2003-04-23 | Uni I Tromsoe | Fremgangsmåte av bioaktiv peptid forberedelse |
US8105615B2 (en) * | 2003-06-06 | 2012-01-31 | Agennix Incorporated | Lactoferrin as an adjuvant in cancer vaccines |
US7419667B2 (en) * | 2004-03-19 | 2008-09-02 | Morinaga Milk Industry Co. Ltd. | Drug for cancer therapy |
KR20070056042A (ko) * | 2004-06-17 | 2007-05-31 | 맨카인드 코포레이션 | 에피토프 유사체 |
US8034762B2 (en) * | 2004-09-02 | 2011-10-11 | Cognosci, Inc. | Treatment of subarachnoid hemorrhage with Apo E analogs |
US7183381B2 (en) * | 2004-10-26 | 2007-02-27 | Agennix, Inc. | Composition of lactoferrin related peptides and uses thereof |
CA2587727A1 (en) * | 2004-11-19 | 2006-05-26 | Jagat Rakesh Kanwar | Methods of immune or haematological enhancement, inhibiting tumour formation or growth, and treating or preventing cancer |
DE102005051366A1 (de) * | 2005-10-25 | 2007-04-26 | Degussa Gmbh | Drug Delivery Systeme |
WO2007055578A1 (en) * | 2005-11-11 | 2007-05-18 | Leids Universitair Medisch Centrum | Cyclic antimicrobial peptides derived from lactoferrin |
US20100061932A1 (en) | 2005-12-30 | 2010-03-11 | Evonik Roehm Gmbh | Peptides useful as cell-penetrating peptides |
ES2321358B1 (es) * | 2006-04-05 | 2010-03-05 | Consejo Susperior De Investigaciones Cientificas | Uso de peptidos derivados de la lactoferrina para preparar formulaciones inhibidoras de la enzima conversora de angiotensina i. |
EP2010561A4 (de) * | 2006-04-27 | 2010-03-24 | Singapore Health Services Pte | Antimikrobielle peptide |
WO2008006125A1 (en) | 2006-07-10 | 2008-01-17 | Österreichische Akademie der Wissenschaften | Antimicrobial peptides |
GB0821616D0 (en) * | 2008-11-26 | 2008-12-31 | Lytix Biopharma As | Compounds |
EP2754450A1 (de) | 2013-01-11 | 2014-07-16 | Österreichische Akademie der Wissenschaften | Aus Lactoferricin abgeleitete Peptide |
GB201401877D0 (en) * | 2014-02-04 | 2014-03-19 | Univ Tromsoe | Peptides |
CN106794218A (zh) * | 2014-10-08 | 2017-05-31 | 学校法人庆应义塾 | 白细胞的细胞外诱捕网形成抑制剂 |
ITUB20153058A1 (it) * | 2015-08-11 | 2017-02-11 | Farmagens Health Care S R L Roma | ?frammento di lattoferrina per uso come agente antibatterico ed antivirale? |
US11213512B2 (en) | 2016-06-21 | 2022-01-04 | The Curators Of The University Of Missouri | Bis-amino acid based compound and use thereof |
US11174288B2 (en) | 2016-12-06 | 2021-11-16 | Northeastern University | Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria |
AU2018312110B2 (en) | 2017-08-04 | 2023-03-16 | Bioventures, Llc | Linear lipopeptide paenipeptins and methods of using the same |
US11236138B2 (en) * | 2020-01-14 | 2022-02-01 | Renorigin Innovation Institute Co., Ltd. | Peptide, method and composition for melanin polymerization and hair darkening |
CN115073352A (zh) * | 2022-06-28 | 2022-09-20 | 吉尔多肽生物制药(大连市)有限公司 | 一种2,5,7-三叔丁基色氨酸的合成方法 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5141581A (en) * | 1972-10-08 | 1992-08-25 | Markham Harold A | Implants with a cover which resists formation of firm spherical encapsulation |
US4476116A (en) * | 1982-12-10 | 1984-10-09 | Syntex (U.S.A.) Inc. | Polypeptides/chelating agent nasal compositions having enhanced peptide absorption |
US5073542A (en) | 1989-06-07 | 1991-12-17 | Magainin Sciences Inc. | CPF peptide compositions and their use in inhibiting growth of target cells or a virus |
DK167813B1 (da) * | 1989-12-07 | 1993-12-20 | Carlbiotech Ltd As | Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat |
US5141851A (en) * | 1990-04-18 | 1992-08-25 | Board Of Regents, The University Of Texas System | Isolated farnesyl protein transferase enzyme |
JP2818056B2 (ja) * | 1990-09-07 | 1998-10-30 | 森永乳業株式会社 | 抗菌性ペプチドおよび抗菌剤 |
DE69220397T2 (de) * | 1991-03-13 | 1997-10-02 | Morinaga Milk Industry Co Ltd | Antimikrobielles Peptid und antimikrobieller Wirkstoff |
CA2111214A1 (en) * | 1991-06-12 | 1992-12-23 | W. Lee Maloy | Composition and treatment with biologically active peptides having c-terminal substitutions |
US5547939A (en) * | 1991-06-14 | 1996-08-20 | The Regents Of The University Of California | Broad spectrum antimicrobial compounds and methods of use |
US5631228A (en) * | 1991-11-01 | 1997-05-20 | Periodontix, Inc. | Anti-fungal and anti-bacterial histatin-based peptides |
US5646119A (en) * | 1991-11-01 | 1997-07-08 | Periodontix, Inc. | D-amino acid histatin-based peptides as anti-fungal and anti-bacterial agents |
CA2128612C (en) | 1992-01-23 | 1999-06-15 | Mamoru Tomita | Antimicrobial agents and method for treating products therewith |
AU674525B2 (en) * | 1992-06-01 | 1997-01-02 | Magainin Pharmaceuticals, Inc. | Biologically active peptides having N-terminal substitutions |
CA2140002A1 (en) * | 1992-07-13 | 1994-01-20 | Jay Stout | A chemical method for selective modification of the n- and/or c-terminal amino acid .alpha.-carbon reactive group of a recombinant polypeptide or a portion thereof |
US5593866A (en) | 1992-08-21 | 1997-01-14 | The University Of British Columbia | Cationic peptides and method for production |
JPH08507749A (ja) | 1992-12-03 | 1996-08-20 | マガイニン ファーマシューティカルズ,インク. | 皮膚悪性疾患の生物学的活性を有するペプチドによる治療 |
JP3312946B2 (ja) * | 1993-03-04 | 2002-08-12 | 雪印乳業株式会社 | ウイルス感染・増殖抑制剤 |
US5789542A (en) * | 1994-04-22 | 1998-08-04 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Amphipathic peptides |
EP0920331A1 (de) * | 1996-08-12 | 1999-06-09 | A+ Science Invest AB | Behandlung und verhütung von infektionen, entzündungen und/oder tumoren mit hilfe von lactoferrin und /oder lactoferricin |
CN1228123A (zh) * | 1996-08-14 | 1999-09-08 | 诺瓦提斯公司 | 对植物病原真菌有抑制活性的肽 |
US6503881B2 (en) * | 1996-08-21 | 2003-01-07 | Micrologix Biotech Inc. | Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics |
WO1998040091A1 (en) * | 1997-03-13 | 1998-09-17 | The Research Foundation Of State University Of New York | Microbicidal peptides and methods of use |
GB9818938D0 (en) | 1998-08-28 | 1998-10-21 | Alpharma As | Bioactive peptides |
-
1998
- 1998-08-28 GB GBGB9818938.4A patent/GB9818938D0/en not_active Ceased
-
1999
- 1999-08-31 AT AT99941773T patent/ATE495192T1/de active
- 1999-08-31 DK DK99941773.6T patent/DK1109831T3/da active
- 1999-08-31 EP EP99941774A patent/EP1109827B1/de not_active Expired - Lifetime
- 1999-08-31 CA CA2341037A patent/CA2341037C/en not_active Expired - Fee Related
- 1999-08-31 CA CA002340326A patent/CA2340326A1/en not_active Abandoned
- 1999-08-31 WO PCT/GB1999/002850 patent/WO2000012541A2/en active IP Right Grant
- 1999-08-31 AU AU55268/99A patent/AU5526899A/en not_active Abandoned
- 1999-08-31 AU AU55267/99A patent/AU772176B2/en not_active Ceased
- 1999-08-31 JP JP2000567559A patent/JP5475937B2/ja not_active Expired - Fee Related
- 1999-08-31 ES ES99941773T patent/ES2359616T3/es not_active Expired - Lifetime
- 1999-08-31 AT AT99941774T patent/ATE513847T1/de not_active IP Right Cessation
- 1999-08-31 DE DE69943130T patent/DE69943130D1/de not_active Expired - Lifetime
- 1999-08-31 EP EP99941773A patent/EP1109831B1/de not_active Expired - Lifetime
- 1999-08-31 WO PCT/GB1999/002851 patent/WO2000012542A2/en active Application Filing
-
2001
- 2001-02-27 US US09/798,869 patent/US6890902B2/en not_active Expired - Fee Related
- 2001-02-27 NO NO20010995A patent/NO333073B1/no not_active IP Right Cessation
- 2001-02-27 US US09/798,026 patent/US7439228B2/en not_active Expired - Fee Related
-
2008
- 2008-07-02 US US12/217,160 patent/US8143211B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NO20010995L (no) | 2001-04-27 |
DK1109831T3 (da) | 2011-04-18 |
US20030022821A1 (en) | 2003-01-30 |
EP1109831B1 (de) | 2011-01-12 |
ES2359616T3 (es) | 2011-05-25 |
US8143211B2 (en) | 2012-03-27 |
EP1109831A2 (de) | 2001-06-27 |
WO2000012542A2 (en) | 2000-03-09 |
JP2002523517A (ja) | 2002-07-30 |
EP1109827A2 (de) | 2001-06-27 |
US7439228B2 (en) | 2008-10-21 |
DE69943130D1 (de) | 2011-02-24 |
AU5526799A (en) | 2000-03-21 |
NO333073B1 (no) | 2013-02-25 |
CA2340326A1 (en) | 2000-03-09 |
AU772176B2 (en) | 2004-04-08 |
WO2000012541A2 (en) | 2000-03-09 |
CA2341037A1 (en) | 2000-03-09 |
US6890902B2 (en) | 2005-05-10 |
JP5475937B2 (ja) | 2014-04-16 |
ATE513847T1 (de) | 2011-07-15 |
EP1109827B1 (de) | 2011-06-22 |
AU5526899A (en) | 2000-03-21 |
WO2000012541A3 (en) | 2000-06-08 |
NO20010995D0 (no) | 2001-02-27 |
GB9818938D0 (en) | 1998-10-21 |
US20080287346A1 (en) | 2008-11-20 |
CA2341037C (en) | 2013-11-05 |
US20030148936A1 (en) | 2003-08-07 |
WO2000012542A3 (en) | 2000-06-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE495192T1 (de) | Mit voluminösen oder lipophilen gruppen modifizierte cyctotoxische peptide | |
ES2103857T3 (es) | Peptidos ciclicos y su uso. | |
ES2163444T3 (es) | Composiciones y metodos para la administracion oral de farmacos. | |
MX172600B (es) | , "procedimiento para la produccion de una proteina biologicamente activa | |
PL344599A1 (en) | Novel cyclosporins | |
IL127352A (en) | Pyridyl alkene- and pyridyl alkine-acid amides and pharmaceutical compositions containing them | |
MY121908A (en) | 3-amidopyrazole derivatives, process for preparing these and pharmaceutical compositions containing them. | |
HUP0100928A2 (hu) | Humán inzulin B láncának részletét tartalmazó peptidanalógok, ezeket tartalmazó gyógyászati készítmények és alkalmazásuk | |
BR9807076B1 (pt) | "uso de acetato de glatirâmero para a fabricação de medicamento para o tratamento de esclerose múltipla e composição farmacêutica" | |
AR013079A1 (es) | Derivados sustituidos de tetrahidrofurano-3-onas, de tetrahidropirano-3- onas y tetrahidrotiofen-3-onas, un procedimiento para su preparacion unacomposicion farmaceutica de un medicamento util como inhibidores de proteasas e intermediarios | |
DE69900756D1 (de) | Verwendung von hmg proteinen zur herstellung von arzneimitteln mit zytotoxischer wirkung | |
FR2647677B1 (fr) | Nouvelles micro-proteines, procede de preparation et application a titre de medicaments de ces nouvelles micro-proteines | |
MX9302327A (es) | Aminoacidos ciclicos novedosos y derivados de los mismos. | |
HK1040237A1 (en) | Fused polycyclic amino acids as pharmaceutical agents. | |
ATE169922T1 (de) | Desoxyazaphospholipid-derivate mit inhibierender aktivität auf phospholipase | |
FR2766489B1 (fr) | Derives de streptogramines, leur preparation et les compositions qui les contiennent | |
AR018328A1 (es) | Forma cristalina de la 1s-[1 alfa(2s*,3r*), 9 alfa-]-6,10-dioxo-n-(2-etoxi-5-oxo-tetrahidro-3-furanil)-9-[[(1-isoquinolil)carbonil]amino]octahidro-6-h-piridazino[1,2-a][1,2] diazepina-1-carboxamida, su procedimiento de preparacion , su aplicacion en la preparacion de un medicamento, y las composicio | |
DE69808287T2 (de) | Pharmazeutische zusammensetzungen von cinchonin dihydrochlorid |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1109831 Country of ref document: EP |