ATE490275T1 - Antikörper gegen interleukin-22 und verwendungen dafür - Google Patents
Antikörper gegen interleukin-22 und verwendungen dafürInfo
- Publication number
- ATE490275T1 ATE490275T1 AT04756337T AT04756337T ATE490275T1 AT E490275 T1 ATE490275 T1 AT E490275T1 AT 04756337 T AT04756337 T AT 04756337T AT 04756337 T AT04756337 T AT 04756337T AT E490275 T1 ATE490275 T1 AT E490275T1
- Authority
- AT
- Austria
- Prior art keywords
- antibodies
- interleukin
- disclosed
- associated immune
- disorders
- Prior art date
Links
- 102100030703 Interleukin-22 Human genes 0.000 title abstract 4
- 108010074109 interleukin-22 Proteins 0.000 title abstract 4
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 101001010626 Homo sapiens Interleukin-22 Proteins 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48065203P | 2003-06-23 | 2003-06-23 | |
| PCT/US2004/020833 WO2005000897A2 (en) | 2003-06-23 | 2004-06-22 | Antibodies against interleukin-22 and uses therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE490275T1 true ATE490275T1 (de) | 2010-12-15 |
Family
ID=33551931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04756337T ATE490275T1 (de) | 2003-06-23 | 2004-06-22 | Antikörper gegen interleukin-22 und verwendungen dafür |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1644415B1 (de) |
| JP (2) | JP2007537132A (de) |
| KR (1) | KR20060022289A (de) |
| CN (1) | CN1839157A (de) |
| AT (1) | ATE490275T1 (de) |
| AU (1) | AU2004252169A1 (de) |
| BR (1) | BRPI0411784A (de) |
| CA (1) | CA2530386A1 (de) |
| CR (1) | CR8211A (de) |
| DE (1) | DE602004030341D1 (de) |
| EC (1) | ECSP066297A (de) |
| ES (1) | ES2354693T3 (de) |
| IL (1) | IL172646A0 (de) |
| MX (1) | MXPA05013881A (de) |
| NI (1) | NI200500230A (de) |
| NO (1) | NO20060189L (de) |
| RU (1) | RU2006101702A (de) |
| WO (1) | WO2005000897A2 (de) |
| ZA (1) | ZA200600608B (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1076703E (pt) | 1998-05-15 | 2007-10-10 | Genentech Inc | ''utilizações terapêuticas de polipéptido homólogos de il-17'' |
| US7771719B1 (en) | 2000-01-11 | 2010-08-10 | Genentech, Inc. | Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E |
| US7718397B2 (en) | 2000-03-21 | 2010-05-18 | Genentech, Inc. | Nucleic acids encoding receptor for IL-17 homologous polypeptides and uses thereof |
| US20030096969A1 (en) | 2000-06-02 | 2003-05-22 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| MX341074B (es) | 2003-07-08 | 2016-08-05 | Genentech Inc | Polipeptidos heterologos il-17 a/f y usos terapeuticos de los mismos. |
| JP4833850B2 (ja) | 2003-11-21 | 2011-12-07 | ユセベ ファルマ ソシエテ アノニム | Il−17活性阻害による多発性硬化症を治療するための方法 |
| SI1915397T1 (sl) | 2005-08-19 | 2015-05-29 | Wyeth Llc | Antagonistična protitelesa proti GDF-8 in uporabe pri zdravljenju ALS in drugih obolenj, povezanih z GDF-8 |
| CA2628703C (en) | 2005-11-30 | 2019-10-29 | Abbott Laboratories | Anti-a.beta. globulomer antibodies, antigen-binding moieties thereof, corresponding hybridomas, nucleic acids, vectors, host cells, methods of producing said antibodies, compositions comprising said antibodies, uses of said antibodies and methods of using said antibodies |
| DK1976877T4 (en) | 2005-11-30 | 2017-01-16 | Abbvie Inc | Monoclonal antibodies to amyloid beta protein and uses thereof |
| EP1954719A2 (de) * | 2005-12-02 | 2008-08-13 | Genentech Inc. | Zusammensetzungen und verfahren zur behandlung von krankheiten und leiden in zusammenhang mit zytokin-signalisierung sowie unter verwendung an il-22 und il-22r bindender antikörper |
| AU2013200914B2 (en) * | 2005-12-02 | 2016-01-14 | Genentech, Inc. | Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to IL-22 and IL-22R |
| AU2007214426A1 (en) * | 2006-02-16 | 2007-08-23 | Nascent Biologics, Inc. | Methods for improving immune function and methods for prevention or treatment of disease in a mammalian subject |
| TWI417301B (zh) | 2006-02-21 | 2013-12-01 | Wyeth Corp | 對抗人類介白素-22(il-22)之抗體及其用途 |
| TW200744634A (en) * | 2006-02-21 | 2007-12-16 | Wyeth Corp | Methods of using antibodies against human IL-22 |
| US20080031882A1 (en) * | 2006-06-19 | 2008-02-07 | Liang Spencer C | Methods of modulating IL-22 and IL-17 |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| WO2008104386A2 (en) | 2007-02-27 | 2008-09-04 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
| WO2008150885A1 (en) * | 2007-05-29 | 2008-12-11 | Board Of Regents, The University Of Texas System | Modulation of the th-17 cell mediated immune responses |
| CN101225110B (zh) * | 2007-10-23 | 2010-10-20 | 中国人民解放军军事医学科学院基础医学研究所 | 人白细胞介素-22突变体及其构建方法和应用 |
| WO2009062102A2 (en) * | 2007-11-07 | 2009-05-14 | Genentech, Inc. | Compositions and methods for treatment of microbial disorders |
| WO2009117640A2 (en) * | 2008-03-21 | 2009-09-24 | Wyeth | Antibodies against interleukin-10 like cytokines and uses therefor |
| NZ588674A (en) | 2008-05-05 | 2013-02-22 | Novimmune Sa | Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof |
| SG175276A1 (en) | 2009-05-05 | 2011-11-28 | Novimmune Sa | Anti-il-17f antibodies and methods of use thereof |
| CN104744591B (zh) | 2010-04-15 | 2022-09-27 | Abbvie德国有限责任两合公司 | β淀粉样蛋白结合蛋白 |
| WO2012024187A1 (en) | 2010-08-14 | 2012-02-23 | Abbott Laboratories | Amyloid-beta binding proteins |
| CN110544517A (zh) | 2011-05-10 | 2019-12-06 | 雀巢产品有限公司 | 用于个体化治疗管理的疾病活动性表征方法 |
| RS57393B1 (sr) | 2013-03-15 | 2018-09-28 | Hoffmann La Roche | Il-22 polipeptiidi i il-22 fuzioni proteini i metode za njihovu upotrebu |
| JP2020513574A (ja) * | 2016-11-24 | 2020-05-14 | ヒュベット バイオ, インコーポレイテッドHuvet Bio, Inc. | 疾患の診断用組成物 |
| EP3585411B1 (de) * | 2017-02-21 | 2025-05-28 | The Regents Of The University Of Michigan | Il-22bp-zusammensetzungen und verfahren zur behandlung von krankheiten damit |
| AU2018277256A1 (en) | 2017-05-31 | 2020-01-30 | Prometheus Biosciences, Inc. | Methods for assessing mucosal healing in Crohn's disease patients |
| KR102536314B1 (ko) * | 2018-05-23 | 2023-05-25 | 주식회사 휴벳바이오 | 질환의 진단용 조성물 |
| KR20210019464A (ko) * | 2018-06-05 | 2021-02-22 | 바이오아트라, 인코퍼레이티드 | 항 il-22 항체, 항체 단편, 이의 면역접합체 및 이의 용도 |
| EP4083058A3 (de) * | 2018-11-07 | 2023-01-11 | Applied Molecular Transport Inc. | Verabreichungskonstrukte für die transzytose und zugehörige verfahren |
| WO2022122652A1 (en) | 2020-12-07 | 2022-06-16 | UCB Biopharma SRL | Antibodies against interleukin-22 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002016611A2 (en) * | 2000-08-24 | 2002-02-28 | Genentech, Inc. | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
| US6939545B2 (en) * | 1999-04-28 | 2005-09-06 | Genetics Institute, Llc | Composition and method for treating inflammatory disorders |
| US20030170823A1 (en) * | 1999-12-23 | 2003-09-11 | Presnell Scott R. | Novel cytokine ZCYTO18 |
| EP1806404B1 (de) * | 2000-07-27 | 2010-08-18 | Wyeth LLC | Verwendung von IL-10 Rezeptor beta antagonistische Antikörper zur Hemmung einer IL-TIF/IL-21 Induktion von Akutphasen-Proteine |
| WO2002068476A2 (en) * | 2001-02-23 | 2002-09-06 | Genetics Institute, Llc | Composition comprising il-22 inhibitors and use thereof for treating inflammatory disorders |
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2004
- 2004-06-22 AT AT04756337T patent/ATE490275T1/de not_active IP Right Cessation
- 2004-06-22 CN CNA2004800237577A patent/CN1839157A/zh not_active Withdrawn
- 2004-06-22 RU RU2006101702/13A patent/RU2006101702A/ru not_active Application Discontinuation
- 2004-06-22 BR BRPI0411784-0A patent/BRPI0411784A/pt not_active IP Right Cessation
- 2004-06-22 ES ES04756337T patent/ES2354693T3/es not_active Expired - Lifetime
- 2004-06-22 AU AU2004252169A patent/AU2004252169A1/en not_active Withdrawn
- 2004-06-22 CA CA002530386A patent/CA2530386A1/en not_active Abandoned
- 2004-06-22 KR KR1020057024826A patent/KR20060022289A/ko not_active Withdrawn
- 2004-06-22 WO PCT/US2004/020833 patent/WO2005000897A2/en not_active Ceased
- 2004-06-22 MX MXPA05013881A patent/MXPA05013881A/es active IP Right Grant
- 2004-06-22 EP EP04756337A patent/EP1644415B1/de not_active Expired - Lifetime
- 2004-06-22 JP JP2006517763A patent/JP2007537132A/ja active Pending
- 2004-06-22 DE DE602004030341T patent/DE602004030341D1/de not_active Expired - Lifetime
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2005
- 2005-12-16 NI NI200500230A patent/NI200500230A/es unknown
- 2005-12-18 IL IL172646A patent/IL172646A0/en unknown
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2006
- 2006-01-12 NO NO20060189A patent/NO20060189L/no not_active Application Discontinuation
- 2006-01-20 EC EC2006006297A patent/ECSP066297A/es unknown
- 2006-01-20 ZA ZA200600608A patent/ZA200600608B/en unknown
- 2006-01-23 CR CR8211A patent/CR8211A/es not_active Application Discontinuation
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2007
- 2007-10-19 JP JP2007273219A patent/JP2008044966A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005000897A3 (en) | 2005-03-31 |
| BRPI0411784A (pt) | 2006-08-08 |
| JP2008044966A (ja) | 2008-02-28 |
| ZA200600608B (en) | 2007-05-30 |
| DE602004030341D1 (de) | 2011-01-13 |
| AU2004252169A1 (en) | 2005-01-06 |
| CA2530386A1 (en) | 2005-01-06 |
| CN1839157A (zh) | 2006-09-27 |
| RU2006101702A (ru) | 2006-09-10 |
| KR20060022289A (ko) | 2006-03-09 |
| ES2354693T3 (es) | 2011-03-17 |
| ECSP066297A (es) | 2006-07-28 |
| NI200500230A (es) | 2008-01-30 |
| IL172646A0 (en) | 2006-04-10 |
| MXPA05013881A (es) | 2008-02-13 |
| EP1644415B1 (de) | 2010-12-01 |
| WO2005000897A2 (en) | 2005-01-06 |
| JP2007537132A (ja) | 2007-12-20 |
| EP1644415A2 (de) | 2006-04-12 |
| NO20060189L (no) | 2006-03-20 |
| CR8211A (es) | 2006-04-27 |
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