ATE485512T1 - Stabile zelllinien und verfahren zur beurteilung der aufnahme von chemikalien im magen-darm-trakt - Google Patents
Stabile zelllinien und verfahren zur beurteilung der aufnahme von chemikalien im magen-darm-traktInfo
- Publication number
- ATE485512T1 ATE485512T1 AT07867410T AT07867410T ATE485512T1 AT E485512 T1 ATE485512 T1 AT E485512T1 AT 07867410 T AT07867410 T AT 07867410T AT 07867410 T AT07867410 T AT 07867410T AT E485512 T1 ATE485512 T1 AT E485512T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- cell lines
- chemicals
- absorption
- assessing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/10—Applications; Uses in screening processes
- C12N2320/12—Applications; Uses in screening processes in functional genomics, i.e. for the determination of gene function
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Plant Pathology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85793806P | 2006-11-10 | 2006-11-10 | |
| US89266507P | 2007-03-02 | 2007-03-02 | |
| PCT/US2007/023688 WO2008060489A2 (en) | 2006-11-10 | 2007-11-09 | Stable cell lines and methods for evaluating gastrointestinal absorption of chemicals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE485512T1 true ATE485512T1 (de) | 2010-11-15 |
Family
ID=39402218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07867410T ATE485512T1 (de) | 2006-11-10 | 2007-11-09 | Stabile zelllinien und verfahren zur beurteilung der aufnahme von chemikalien im magen-darm-trakt |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US7795019B2 (de) |
| EP (1) | EP2084529B1 (de) |
| JP (3) | JP5324456B2 (de) |
| AT (1) | ATE485512T1 (de) |
| CA (1) | CA2669013C (de) |
| DE (1) | DE602007010019D1 (de) |
| DK (1) | DK2084529T3 (de) |
| PA (1) | PA8755401A1 (de) |
| SI (1) | SI2084529T1 (de) |
| WO (1) | WO2008060489A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010022151A1 (en) * | 2008-08-19 | 2010-02-25 | Absorption Systems Group Llc | Methods of transporting epithelial cell monolayers |
| EP2659404B1 (de) * | 2010-12-29 | 2018-08-08 | Sigma-Aldrich Co., LLC | Zellen mit gestörter expression von in adme und toxikologieverfahren involvierten proteinen |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU217108B (hu) | 1994-08-31 | 1999-11-29 | SOLVO Biotechnológiai Kft. | Eljárás daganatok multidrogrezisztenciáját okozó fehérje aktivitásának in vitro mennyiségi kimutatására biológiai mintákban |
| US7601494B2 (en) * | 1999-03-17 | 2009-10-13 | The University Of North Carolina At Chapel Hill | Method of screening candidate compounds for susceptibility to biliary excretion |
| US20050048468A1 (en) * | 2003-08-27 | 2005-03-03 | Bio-Rad Laboratories, Inc. | Multiconstituent liquid lgG and IgM calibrators |
| EP1723259A2 (de) * | 2004-03-12 | 2006-11-22 | The Queens University of Belfast | Krebsbehandlung und tests zur bestimmung der resistenz gegenüber einem chemotherapeutikum auf platinbasis |
| WO2006021894A2 (en) * | 2004-08-26 | 2006-03-02 | Engeneic Gene Therapy Pty Limited | Delivering functional nucleic acids to mammalian cells via bacterially derived, intact minicells |
-
2007
- 2007-11-09 DE DE602007010019T patent/DE602007010019D1/de active Active
- 2007-11-09 CA CA2669013A patent/CA2669013C/en active Active
- 2007-11-09 SI SI200730479T patent/SI2084529T1/sl unknown
- 2007-11-09 EP EP07867410A patent/EP2084529B1/de active Active
- 2007-11-09 AT AT07867410T patent/ATE485512T1/de not_active IP Right Cessation
- 2007-11-09 US US11/938,065 patent/US7795019B2/en active Active
- 2007-11-09 DK DK07867410.8T patent/DK2084529T3/da active
- 2007-11-09 JP JP2009536326A patent/JP5324456B2/ja not_active Expired - Fee Related
- 2007-11-09 WO PCT/US2007/023688 patent/WO2008060489A2/en active Search and Examination
- 2007-11-12 PA PA20078755401A patent/PA8755401A1/es unknown
-
2010
- 2010-07-26 US US12/843,706 patent/US8110398B2/en active Active
- 2010-07-26 US US12/843,536 patent/US8105828B2/en active Active
-
2012
- 2012-01-10 US US13/347,544 patent/US20120142008A1/en not_active Abandoned
-
2013
- 2013-07-17 JP JP2013148506A patent/JP2013240341A/ja active Pending
- 2013-07-17 JP JP2013148504A patent/JP2013240340A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2084529A2 (de) | 2009-08-05 |
| WO2008060489A9 (en) | 2009-06-18 |
| JP2010508849A (ja) | 2010-03-25 |
| EP2084529B1 (de) | 2010-10-20 |
| US8105828B2 (en) | 2012-01-31 |
| US20100317049A1 (en) | 2010-12-16 |
| PA8755401A1 (es) | 2009-07-23 |
| SI2084529T1 (sl) | 2011-02-28 |
| CA2669013A1 (en) | 2008-05-22 |
| DE602007010019D1 (de) | 2010-12-02 |
| JP2013240341A (ja) | 2013-12-05 |
| DK2084529T3 (da) | 2011-02-07 |
| US20100311082A1 (en) | 2010-12-09 |
| WO2008060489A2 (en) | 2008-05-22 |
| JP5324456B2 (ja) | 2013-10-23 |
| US20080124734A1 (en) | 2008-05-29 |
| WO2008060489A3 (en) | 2008-10-30 |
| JP2013240340A (ja) | 2013-12-05 |
| US20120142008A1 (en) | 2012-06-07 |
| US8110398B2 (en) | 2012-02-07 |
| CA2669013C (en) | 2015-04-14 |
| US7795019B2 (en) | 2010-09-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |